The discussions reflect high enthusiasm, with posts describing the research as 'really exciting' and 'incredible', and highlighting its potential to revolutionize aging studies. Words like 'opens new paths', 'proof of principle', and mentions of the study's role in extending lifespan indicate a strong belief in its transformative impact, supported by references to the gene Has2 and hyaluronan's benefits.
AgreementStrong agreement
The majority of discussions express strong support or excitement about the findings, emphasizing the significance of transferring longevity mechanisms across species.
InterestHigh interest
Most posts show high interest, with many calling the research 'exciting', 'incredible', or highlighting its potential for age-related health benefits.
EngagementHigh engagement
Many discussions delve into detailed analysis, referencing specific genes, mechanisms, and potential applications, indicating deep engagement.
ImpactHigh impact
Posts emphasize high impact, pointing to the research's potential to influence future anti-aging strategies, extend lifespan, and benefit human health.
Abstract in brief
The study investigates how increasing high-molecular-mass hyaluronic acid (HMMHA), a substance linked to cancer resistance and longevity in naked mole-rats, can benefit other species by using genetically modified mice that produce more of this compound.
The transgenic mice with higher HMMHA levels showed reduced cancer rates, longer lifespans, improved health, and decreased inflammation across their tissues, mimicking traits associated with longer-lived species.
These results suggest that the mechanisms for longevity in naked mole-rats can be transferred to other animals, highlighting potential paths for enhancing lifespan and healthspan through HMMHA-based treatments.]
Excited to share that our 9-year research effort has been published in @Nature. We found that the mechanisms from long-lived species can be replicated and proven functional in other species. Congrats to Gorbunova, @gladyshev_lab and @prof_horvath labs.
https://t.co/wwerem6vbG
Aug 26, 2023 · 130 likes · 29 shares · 313 followersView post →
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nature
@Nature · X
Nature research paper: Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice https://t.co/YJPvTUMpNZ
Aug 24, 2023 · 53 likes · 16 shares · 2,554,078 followersView post →
Cool paper from Vera Gorbunova and colleagues: Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice | Nature https://t.co/NaKPIpg4e4
Aug 24, 2023 · 23 likes · 8 shares · 5,098 followersView post →
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Pankaj kapahi
@kapahi_pankaj · X
Really exciting study!! Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice | Nature https://t.co/HbSYbOoxJi
Aug 24, 2023 · 21 likes · 2 shares · 2,921 followersView post →
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Agingdoc
@agingdoc1 · X
Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice
Aug 24, 2023 · 19 likes · 4 shares · 44,124 followersView post →
This video explores how metabolic signals, particularly GLP1, influence learning processes related to sensory cues and behaviors. It highlights that GLP1 receptor agonist liraglutide can restore impaired associative…
Hosts Max Jay and Gabe explore groundbreaking scientific discoveries including microplastic-decomposing microrobots, deep-sea octopus behavior, and newly uncovered ancient dance floors. Insights into environmental…
Mice with naked mole-rat gene nmrHas2 live longer, healthier lives due to increased hyaluronan levels reducing inflammation and cancer. This could open new paths for longevity research. #Longevity #Genetics #Healthspan https://t.co/nvIeHlpjTN https://t.co/pggvTyk92Q
الفئران التي تحتوي على جين الخلد العاري nmrHas2 تعيش حياة أطول وأكثر صحة بسبب زيادة مستويات الهيالورونان التي تقلل من الالتهاب والسرطان. هذا قد يفتح طرقًا جديدة لأبحاث الطول العمر. #الطول_العمر #الجينات #الصحة https://t.co/kjoxo9yMWw https://t.co/UDu0pcNFom
RT @XiaoTianPhD: Excited to share that our 9-year research effort has been published in @Nature. We found that the mechanisms from long-liv…
Nov 2, 2023 · 29 shares · 589 followersView post →
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Austin Argentieri
@austinargen · X
Pretty incredible. The authors took a known longevity mechanism (HMM-HA) from one species (naked mole rat) and over expressed it in another (mice). Improved lifespan/healthspan and decreased inflammation. Bodes well for the future of anti-aging research. https://t.co/sAGZpx8fPc
RT @XiaoTianPhD: Excited to share that our 9-year research effort has been published in @Nature. We found that the mechanisms from long-liv…
Nov 2, 2023 · 29 shares · 3,807 followersView post →
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Vanja Tepavcevic
@TepavcevicVanja · X
RT @XiaoTianPhD: Excited to share that our 9-year research effort has been published in @Nature. We found that the mechanisms from long-liv…
Nov 2, 2023 · 29 shares · 915 followersView post →
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Sarah Moyon
@NeuroSarah · X
RT @XiaoTianPhD: Excited to share that our 9-year research effort has been published in @Nature. We found that the mechanisms from long-liv…
Nov 2, 2023 · 29 shares · 686 followersView post →
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Prof Steve Horvath
@prof_horvath · X
RT @XiaoTianPhD: Excited to share that our 9-year research effort has been published in @Nature. We found that the mechanisms from long-liv…
Nov 2, 2023 · 29 shares · 7,632 followersView post →
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The Academy for Health & Lifespan Research
@ahlresearch · X
This study on high-molecular-mass hyaluronic acid found that transgenic mice with elevated levels of a specific naked mole-rat gene had reduced cancer, longer lives, and better health. Professor Vera Gorbunova played a key role.
Learn more: https://t.co/jQninZSw2Z https://t.co/W1jcq6UKvX
Oct 31, 2023 · 6 likes · 4,619 followersView post →
DB
Dr. M. Bernardo
@mbernardo321 · X
Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice https://t.co/F8JuMQr8Jo https://t.co/028bldekWk
RT @XiaoTianPhD: Excited to share that our 9-year research effort has been published in @Nature. We found that the mechanisms from long-liv…
Aug 31, 2023 · 29 shares · 7,217 followersView post →
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ToyookaLab
@LabToyooka · X
This is an interesting paper about aging, inspired by naked mole rats.
#neuroscience #aging #inflammation #lifespan #senescence
https://t.co/Yfd4a22WlS
https://t.co/pgw2k3DSrZ
RT @XiaoTianPhD: Excited to share that our 9-year research effort has been published in @Nature. We found that the mechanisms from long-liv…
Aug 29, 2023 · 29 shares · 26 followersView post →
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Science!
@IoniaScience · X
This study serves as proof of principle that unique longevity mechanisms in one species can potentially benefit others. It opens exciting possibilities for extending human lifespan.
DOI:10.1038/s41586-023-06463-0
Aug 29, 2023 · 9 likes · 72,652 followersView post →
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Ansa Cobham
@ansacobham · X
RT @kapahi_pankaj: Really exciting study!! Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice | Nature h…
Aug 28, 2023 · 2 shares · 311 followersView post →
JO
Juan Too Manny Strong Opinions
@TheMainManManny · X
RT @XiaoTianPhD: Excited to share that our 9-year research effort has been published in @Nature. We found that the mechanisms from long-liv…
Aug 28, 2023 · 29 shares · 422 followersView post →
FE
Feyza Engin
@EnginLaboratory · X
Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice | Nature https://t.co/KjqefSDzxC
Aug 28, 2023 · 9 likes · 1,773 followersView post →
BL
Ben Lerch
@BenLerch1 · X
RT @XiaoTianPhD: Excited to share that our 9-year research effort has been published in @Nature. We found that the mechanisms from long-liv…
Aug 28, 2023 · 29 shares · 555 followersView post →
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Becca Mellema- I voted!
@beccmel2 · X
RT @ISHAS_org: Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice https://t.co/AyFmZ4ViLS
RT @agingdoc1: Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice
Aug 28, 2023 · 4 shares · 6,614 followersView post →
PF
Paul Fowler
@GrumpybaldProf · X
RT @Loose_Lab_Rat: Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice https://t.co/cVO0hSX7dd
Aug 28, 2023 · 1 share · 1,207 followersView post →
KD
Kelly A. Hogan Ph.D.
@Loose_Lab_Rat · X
Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice https://t.co/cVO0hSX7dd
Aug 28, 2023 · 4 likes · 1 share · 2,238 followersView post →
AT
Amit Tal
@Amit_D_Tal · X
RT @XiaoTianPhD: Excited to share that our 9-year research effort has been published in @Nature. We found that the mechanisms from long-liv…
Aug 28, 2023 · 29 shares · 195 followersView post →
PD
Patty Doyle
@phdoyleneuro · X
RT @XiaoTianPhD: Excited to share that our 9-year research effort has been published in @Nature. We found that the mechanisms from long-liv…
Aug 27, 2023 · 29 shares · 728 followersView post →
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Holtz
@Biorealism · X
RT @XiaoTianPhD: Excited to share that our 9-year research effort has been published in @Nature. We found that the mechanisms from long-liv…
Aug 27, 2023 · 29 shares · 8,999 followersView post →
KE
Kal-El △
@The_Kal_El_ · X
RT @XiaoTianPhD: Excited to share that our 9-year research effort has been published in @Nature. We found that the mechanisms from long-liv…
Aug 27, 2023 · 29 shares · 4,823 followersView post →
KE
Kal-El △
@The_Kal_El_ · X
RT @alfonslopeztena: Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice — By inserting hyaluronic acid from African na…
Aug 27, 2023 · 5 shares · 4,823 followersView post →
PG
Paola De Gennaro
@PaolaDeGennar10 · X
RT @XiaoTianPhD: Excited to share that our 9-year research effort has been published in @Nature. We found that the mechanisms from long-liv…
Aug 27, 2023 · 29 shares · 219 followersView post →
GL
Gomes Lab
@lab_gomes · X
RT @XiaoTianPhD: Excited to share that our 9-year research effort has been published in @Nature. We found that the mechanisms from long-liv…
Aug 27, 2023 · 29 shares · 1,866 followersView post →
SS
Sovanny Taylor (Sophie)
@sovannyruth · X
RT @XiaoTianPhD: Excited to share that our 9-year research effort has been published in @Nature. We found that the mechanisms from long-liv…
Aug 27, 2023 · 29 shares · 148 followersView post →
HP
Hsiao-Tuan Chao (赵孝端), MD PhD
@HTChaoLab · X
RT @XiaoTianPhD: Excited to share that our 9-year research effort has been published in @Nature. We found that the mechanisms from long-liv…
Aug 27, 2023 · 29 shares · 918 followersView post →
BE
Brad English
@brad_w_e · X
RT @XiaoTianPhD: Excited to share that our 9-year research effort has been published in @Nature. We found that the mechanisms from long-liv…
Aug 27, 2023 · 29 shares · 1,255 followersView post →
TL
The Phoenix Lab
@The_Phoenix_Lab · X
RT @XiaoTianPhD: Excited to share that our 9-year research effort has been published in @Nature. We found that the mechanisms from long-liv…
Aug 27, 2023 · 29 shares · 215 followersView post →
PG
Patrick Griffin
@patrick_griffN · X
RT @XiaoTianPhD: Excited to share that our 9-year research effort has been published in @Nature. We found that the mechanisms from long-liv…
Aug 27, 2023 · 29 shares · 770 followersView post →
TB
Trevor used to be from binghamton
@TrevorTowner1 · X
RT @XiaoTianPhD: Excited to share that our 9-year research effort has been published in @Nature. We found that the mechanisms from long-liv…
Aug 27, 2023 · 29 shares · 247 followersView post →
TR
Taranjit Singh Rai
@RaiLabCTRIC · X
RT @XiaoTianPhD: Excited to share that our 9-year research effort has been published in @Nature. We found that the mechanisms from long-liv…
Aug 27, 2023 · 29 shares · 542 followersView post →
BB
Bernie Buss
@BernieBuss · X
RT @XiaoTianPhD: Excited to share that our 9-year research effort has been published in @Nature. We found that the mechanisms from long-liv…
Aug 27, 2023 · 29 shares · 225 followersView post →
DT
Diego Taquiri
@diego_taquiri · X
RT @XiaoTianPhD: Excited to share that our 9-year research effort has been published in @Nature. We found that the mechanisms from long-liv…
Aug 27, 2023 · 29 shares · 451 followersView post →
AT
Alex Trapp
@AlexandreTrapp · X
RT @XiaoTianPhD: Excited to share that our 9-year research effort has been published in @Nature. We found that the mechanisms from long-liv…
Aug 27, 2023 · 29 shares · 1,208 followersView post →
HL
Hongjie Li
@HongjieLi5 · X
RT @XiaoTianPhD: Excited to share that our 9-year research effort has been published in @Nature. We found that the mechanisms from long-liv…
Aug 26, 2023 · 29 shares · 1,132 followersView post →
XT
Xiao Tian
@XiaoTianPhD · X
Excited to share that our 9-year research effort has been published in @Nature. We found that the mechanisms from long-lived species can be replicated and proven functional in other species. Congrats to Gorbunova, @gladyshev_lab and @prof_horvath labs.
https://t.co/wwerem6vbG
Aug 26, 2023 · 130 likes · 29 shares · 313 followersView post →
WF
Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry · X
Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice
https://t.co/hE8flvGtpG
Transfieren con éxito de una especie a otra un gen que alarga la vida
https://t.co/JPlydmMavW
Más información:
Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice
https://t.co/BGqweKp2bB
Aug 24, 2023 · 46 shares · 383 followersView post →
RH
Rich Hilliard
@dJdU · X
RT @alfonslopeztena: Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice — By inserting hyaluronic acid from African na…
Aug 24, 2023 · 5 shares · 348 followersView post →
JL
Jose Loera
@JoseLoera · X
RT @alfonslopeztena: Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice — By inserting hyaluronic acid from African na…
Aug 24, 2023 · 5 shares · 1,128 followersView post →
AT
Alfons López Tena
@alfonslopeztena · X
Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice — By inserting hyaluronic acid from African naked mole-rat genes into common mice, their maximum lifespan extended by 12% while making them more resistant to cancer https://t.co/Rx0G44yBNl
Aug 24, 2023 · 8 likes · 5 shares · 187,156 followersView post →
SA
Saber Atualizado
@AtualizadoSaber · X
(2) REFERÊNCIA:
Zhang et al. (2023). Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice. Nature. https://t.co/ZuLGnGzl5Q
RT @CircadianClocks: Cool paper from Vera Gorbunova and colleagues: Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice…
Aug 24, 2023 · 8 shares · 2,401 followersView post →
JT
Joseph Takahashi
@CircadianClocks · X
Cool paper from Vera Gorbunova and colleagues: Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice | Nature https://t.co/NaKPIpg4e4
Aug 24, 2023 · 23 likes · 8 shares · 5,098 followersView post →
AE
Ariakas Enoreth
@Aenoreth · X
RT @kipnislab: Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice | Nature “These findings demonstrate that evolutiona…
Aug 24, 2023 · 11 shares · 1,012 followersView post →
JA
Jose P López-Atalaya
@JPLopezAtalaya · X
RT @Nature: Nature research paper: Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice https://t.co/YJPvTUMpNZ
Aug 24, 2023 · 16 shares · 981 followersView post →
む
むらさき
@selfishvector · X
Has2はそうなの?
同じようなヒアルロン酸合成酵素のHas1はガンで上昇する遺伝子で、発現多いと予後が悪いんじゃなかったっけ。。
Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice | Nature https://t.co/Wzf6yW3jfH
DOI: 10.1038/s41586-023-06463-0 The study was funded by the National Institutes of Health. New Breakthrough Paves the Way for Extending Human Lifespan ...