August 2023 PMID 37620370

Major depressive disorder.

Wolfgang Marx, Brenda W J H Penninx, Marco Solmi, Toshi A Furukawa, Joseph Firth, Andre F Carvalho, Michael Berk

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Mentions

230
Peak: 186 in Oct 2025
across 6 sources since Jun 2024

Extended reach

6,959,887
potential audience

Total likes

1,275

Video views

5,315

Mentions per month

Jun 2024 – Oct 2025

Where it's discussed

  • Bluesky120 posts
  • X / Twitter100 posts
  • Facebook3 posts
  • News3 articles
  • YouTube2 videos
  • Blogs2 articles

AI synopsis

What people are saying

Many discussions center around personal experiences with major depressive disorder, showcasing a plethora of sentiments about its challenges and treatment options. For instance, one contributor expressed relief at finally receiving a diagnosis, while another criticized the oversimplification of depression in popular media. Phrases like 'it hurts every morning' and 'I’m just waiting on when I'll snap out of it' underscore the ongoing struggle. The tone of these discussions, often blending humor with profound frustration, reveals the complexity of living with major depressive disorder and points to a collective desire for greater understanding and support.

AgreementModerate agreement

Most discussions reflect a shared understanding and acknowledgment of major depressive disorder's complexities and treatments.

InterestHigh interest

Participants show a strong curiosity about the intersections of mental health and recent research, especially regarding new treatment options.

EngagementModerate engagement

While many posts express personal experiences or references treatments, deeper discussions on methodologies and efficacy are less common.

ImpactHigh impact

Contributors perceive the publication and associated discussions as having substantial implications for awareness and treatment in mental health.

Abstract in brief

  • Major depressive disorder (MDD) involves a prolonged depressed mood, loss of interest in activities, recurrent thoughts of death, and various physical and cognitive symptoms, leading to a decreased quality of life.
  • MDD is complex, resulting from an interplay of genetic, environmental, psychological, and biological factors rather than a single cause.
  • Treatment typically includes antidepressant medications, psychotherapy, or both, and in severe cases, additional treatments like electroconvulsive therapy may be used.

Top posts

Most liked on X and Bluesky
TINY
@tinydragon.art · Bluesky

A bit of vent art. Probably have Major Depressive Disorder. Went through a bout of it again after Covid. I want to come up with some solutions to help me feel better when I'm in it, but when I'm depressed I don't see a point, and when I'm feeling okay, I can't recall how it felt to be depressed.

Oct 4, 2025 · 324 likes · 72 shares View post →
Dr. Samantha Hancox-Li
@sjshancoxli.liberalcurrents.com · Bluesky

legitimately i really do wish people would stop mistaking their own major depressive disorder for politics. it would be better for themselves and also the world

Oct 11, 2025 · 282 likes · 47 shares View post →
Tongam Rina
@tongamrina · X

For years, I suffered from major depressive disorder, anxiety disorder, panic attack, and post traumatic stress disorder (PTSD), often wanting to end it all. Those of you who suffer from } #mentalillness know how debilitating it is. Thanks to the psychiatrist, therapist, loved

Oct 15, 2025 · 56 likes · 6 shares · 15,601 followers View post →
Mary Fernando M.D.
@maryfernando.bsky.social · Bluesky

Oct 2, 2025 · 32 likes · 25 shares View post →
Redd❤️ #RichAuntieVibez
@thegoddessinred · X

@Denita_fit It’s called Perinatal Depression and it’s a modifier of Major Depressive Disorder…your claim is why they changed the name https://t.co/bRE2uSnwR6

Oct 15, 2025 · 30 likes · 4,880 followers View post →
atari ˚.⋆
@atari404 · X

i'm like if spongebob had major depressive disorder https://t.co/o015tPlrZn https://t.co/xF5JShsRhF

Oct 16, 2025 · 29 likes · 1 share · 3,160 followers View post →

All mentions

Dr Abdul Hameed
@drabdulhameed07 · X

@MoarSahitoPTI

Oct 17, 2025 · 1 like · 3,257 followers View post →
The Patient-Centered Outcomes Research Institute
@PCORI · X

The latest edition of PCORI’s Emerging Health Care Innovation Brief highlights FDA clearance to BrainsWay for their Deep Transcranial Magnetic Stimulation system protocol to reduce major depressive disorder treatment time from 4 weeks to 6 days, among other regulatory updates. https://t.co/NOgvZ8scJo

Oct 17, 2025 · 1 like · 20,798 followers View post →
The mood doctor
@Chulbulpanda420 · X

RT @Chulbulpanda420: We handle Premenstrual syndrome, We handle Premenstrual dysphoric disorder, We handle Postpartum depression, We handle…

Oct 17, 2025 · 2 shares · 12,476 followers View post →
DisgruntledAandolanjeevi #DestroyTheAadhaar
@SanskariStree · X

RT @tongamrina: For years, I suffered from major depressive disorder, anxiety disorder, panic attack, and post traumatic stress disorder (P…

Oct 17, 2025 · 6 shares · 3,297 followers View post →
DeScAI agent
@longevity_agent · X

@MoarSahitoPTI Sertraline is primarily known as a selective serotonin reuptake inhibitor (SSRI) used to treat major depressive disorder, anxiety disorders, obsessive-compulsive disorder (OCD), and post-traumatic stress disorder (PTSD).

Oct 17, 2025 · 729 followers View post →
Raging Nana
@KatieRiceWray · X

I have ADD and Major Depressive Disorder. The depression has been treated for decades. After the ADD was diagnosed at 50 I took my first Adderal and I was PISSED because I realized that THIS was how most people feel most of the time. https://t.co/KbLGrpGh0L

Oct 17, 2025 · 4,330 followers View post →
KriMeera Pharma
@KrimeeraPharma · X

@MoarSahitoPTI Sertraline is an antidepressant — specifically, it’s in the class of SSRIs (selective serotonin‐reuptake inhibitors).  It’s commonly used to treat: •Major depressive disorder (depression)  •Anxiety disorders (such as social anxiety disorder)  •Obsessive-Compulsive

Oct 17, 2025 · 277 followers View post →
SOUMYEN ADHIKARI
@soumyen2314 · X

RT @Chulbulpanda420: We handle Premenstrual syndrome, We handle Premenstrual dysphoric disorder, We handle Postpartum depression, We handle…

Oct 17, 2025 · 2 shares · 88 followers View post →
Peanut
@p3ex_isdead · X

Cavity so bad it's eaten almost half my tooth but yeah it's my fault and I totally wanted this it's not because I have a major depressive disorder no way https://t.co/weqwiZnK1u

Oct 17, 2025 · 125 followers View post →
htw
@heniek-htw.bsky.social · Bluesky

Molecular Reflection of the Mind: Exosomes in Major Depressive Disorder www.sciencedirect.com/science/arti...

Oct 17, 2025 View post →
Front Line Genomics
@FLGenomics · X

We’re delighted that Dame Carol Robinson (Director, @KavliOxford) will be at The Festival of Genomics and Biodata in London, discussing how #proteomics technologies can be applied to identify and validate novel drug targets for major depressive disorder. More info: https://t.co/MELfptNG15

Oct 17, 2025 · 11,620 followers View post →
Lil Witchy - Stream My Music!
@witchymustdie · X

Excuses are almost never justified, I have had major depressive disorder my whole life to the point where there were years I couldn’t take care of myself and I still figured shit out all alone and my biggest problem back then was blaming everyone but myself.

Oct 17, 2025 · 816 followers View post →
DPS Health And Wellness
@dpswellness · X

The Impact of Lifestyle Factors on Major Depressive Disorder: Prioritizing Mental Health in Statesboro, Georgia - https://t.co/9m33MjjBRw

Oct 17, 2025 · 4 followers View post →
The mood doctor
@Chulbulpanda420 · X

We handle Premenstrual syndrome, We handle Premenstrual dysphoric disorder, We handle Postpartum depression, We handle perimenopausal mood changes, We handle Bipolar affective disorders, We also handle Major depressive disorder, So We can handle women mood swings. But still you https://t.co/ZCrsF5fQQi

Oct 17, 2025 · 15 likes · 2 shares · 12,476 followers View post →
The mood doctor
@Chulbulpanda420 · X

We handle Premenstrual syndrome, We handle Premenstrual dysphoric disorder, We handle Postpartum depression, We handle perimenopausal mood changes, We handle Bipolar affective disorders, We also handle Major depressive disorder, So We can handle women mood swings. But still you https://t.co/ZCrsF5fQQi

Oct 17, 2025 · 1 like · 12,476 followers View post →
⋆˚༉ aki
@v4in_ak1 · X

@redjelyfishgirl its not a site, but an “easter egg” i made ^w^ they are my diagnosis .ᐟ F32 — major depressive disorder F50 — anorexia 584 — autism 542 — ocd working to get the last two diagnosed officially, it takes time to get into the tests and result + official paperwork, but i have them :)

Oct 17, 2025 · 1 like · 6,562 followers View post →
Sham Bade
@bade_sham20141 · X

https://t.co/1CwSzLzvu5

Oct 17, 2025 View post →
#NeuroDegeneration preprints
@prepub-neurodegen.bsky.social · Bluesky

Cell-Type-Specific Transcriptomic Signatures in Prefrontal Cortex Reveal lncRNA-mediated Gene Silencing and Enhancer Activities Contributing to the Pathophysiology of Major Depressive Disorder #NeuroDegeneration

Oct 17, 2025 View post →
rohini Sanap
@SanapRohin43266 · X

https://t.co/5tTYLQmMko

Oct 17, 2025 · 1 followers View post →
bioRxivpreprint
@biorxivpreprint.bsky.social · Bluesky

Cell-Type-Specific Transcriptomic Signatures in Prefrontal Cortex Reveal lncRNA-mediated Gene Silencing and Enhancer Activities Contributing to the Pathophysiology of Major Depressive Disorder https://www.biorxiv.org/content/10.1101/2025.10.16.682876v1

Oct 16, 2025 View post →
bioRxiv Genomics
@biorxiv-genomic.bsky.social · Bluesky

Cell-Type-Specific Transcriptomic Signatures in Prefrontal Cortex Reveal lncRNA-mediated Gene Silencing and Enhancer Activities Contributing to the Pathophysiology of Major Depressive Disorder https://www.biorxiv.org/content/10.1101/2025.10.16.682876v1

Oct 16, 2025 View post →
Texans for Greater Mental Health
@T4GMH · X

RT @gjurvetson: This is outstanding. 5 years post treatment with psilocybin therapy (for major depressive disorder), 67% were in remissio…

Oct 16, 2025 · 2 shares · 103 followers View post →
♪.
@_cherricherie · X

RT @atari404: i'm like if spongebob had major depressive disorder https://t.co/o015tPlrZn

Oct 16, 2025 · 1 share · 69 followers View post →
turkeyneck1349.bsky.social
@turkeyneck1349.bsky.social · Bluesky

Self-medicatin against major depressive disorder with a wide array of DEPRESSANTS, it's akin to tryna put out a conflagration with a can of gasoline -- at BEST, it's very counter-productive; typically, it turns out plenty worse'n THAT, you dig it? Ameliorating MY Misery demands STIMULATION;

Oct 16, 2025 · 1 share View post →
atari ˚.⋆
@atari404 · X

i'm like if spongebob had major depressive disorder https://t.co/o015tPlrZn https://t.co/xF5JShsRhF

Oct 16, 2025 · 29 likes · 1 share · 3,160 followers View post →
Jim Bloom
@jimmyroybloom · X

RT @jimmyroybloom: https://t.co/kHUMkKIyGQ via @YouTube Biobanking in everyday clinical practice in psychiatry— Translational research…

Oct 16, 2025 · 2 shares · 2,428 followers View post →
Dr. B
@Vintage80sbaby · X

Clearly I know about Major Depressive Disorder like the back of my head.

Oct 16, 2025 · 1,653 followers View post →
DPS Health And Wellness
@dpswellness · X

Exploring Treatment Options for Major Depressive Disorder - https://t.co/44FBiw7Xen https://t.co/rxy2P5HYzj

Oct 16, 2025 · 4 followers View post →
Kartik
@Kartik1167430 · X

https://t.co/u13uCHYJan

Oct 16, 2025 View post →
Syrentis Research
@Syrentis1 · X

Not seeing improvement for your major depressive disorder? You may be eligible for a research study in Santa Ana exploring an investigational treatment option for adults 18 to 64 years old. Call today. (800) NEW-STUDY | https://t.co/u1TsVA4RvJ #depressionstudy #MDD #ClinicalTrial https://t.co/ZCerG5KTSr

Oct 16, 2025 · 344 followers View post →
MIN
@WiseGirl250 · X

I have seasonal depression where I'm depressed during the hotter months instead of the cold ones so now that it's fall I'm 10x more productive and happy than I was all summer...I have major depressive disorder so life kinda sucks all year round for me but it sucks kinda less now

Oct 16, 2025 · 10 likes · 426 followers View post →
kevin day’s defense attorney
@parrishcunt · X

cant believe major depressive disorder is actually majorly depressive and disordering my life

Oct 16, 2025 · 3 likes · 111 followers View post →
niz
@nizzlywizzly · X

@witheringfrenzy Diagnosed major depressive disorder at 11 and it’s made my life #miserable ! At least with my bipolar 2 I know the emotions won’t last forever dykwim?

Oct 16, 2025 · 1 like · 240 followers View post →
princess ౨ৎ
@puppetgrl_ · X

major depressive disorder sucks actually

Oct 16, 2025 · 2 likes · 885 followers View post →
esanum
@esanum · X

@MoarSahitoPTI ✅ Answer: SSRI for major depressive disorder and anxiety spectrum (OCD, PTSD, panic, social anxiety, PMDD)

Oct 16, 2025 · 1 like · 5,531 followers View post →
Meredith Nudo
@meredithnudo.blacksky.app · Bluesky

P.S. There is no reason to give me reassurance or comfort, because I'm not asking for it. I'm an old pro at handling this major depressive disorder stuff, so I *know* I'll snap out of it and get better. I'm just waiting on *when*

Oct 16, 2025 · 2 likes · 1 share View post →
mizu
@rotmarrow · X

RT @FranceShedtwt: me when i was diagnosed with major depressive disorder instead of funny guy disorder https://t.co/U7lvr47iXh

Oct 16, 2025 · 4 shares · 8 followers View post →
˖°.
@freckledn · X

that major depressive disorder be hitting sometimes https://t.co/wDrpnRwEMz

Oct 16, 2025 · 3 likes · 125,387 followers View post →
fistfuck
@ladiesmnn217 · X

@blyyyd bro like major depressive disorder and schizophrenia run RAMPANT in my family brah i know i can handle it for the most part but my kid??? i wouldn't ever want to give them that cross to bear

Oct 16, 2025 · 1 like · 344 followers View post →
Interstellar
@mbira_raww · X

RT @BodyExplained: @MoarSahitoPTI known for treating Major depressive disorder (MDD) Obsessive-compulsive disorder (OCD) Panic disorder…

Oct 16, 2025 · 2 shares · 77 followers View post →
Ⓥ Joyboy the Soyboy
@STOPHEATHERTIME · X

@Chan_Channnnn @Denita_fit @therealchilotam She defined it as the abrupt drop in estrogen and progesterone. That occurs when a lot of tissue and an entire organ are expelled out of the uterus and vagina. What you described are usual causes of Major Depressive Disorder and it’s very serious and requires therapy.

Oct 16, 2025 · 10 likes · 5,090 followers View post →
Ved_Borah
@VedBorah · X

RT @tongamrina: For years, I suffered from major depressive disorder, anxiety disorder, panic attack, and post traumatic stress disorder (P…

Oct 16, 2025 · 6 shares · 4,940 followers View post →
DPS Health And Wellness
@dpswellness · X

Understanding Major Depressive Disorder: An Overview - https://t.co/A30IaqFnp7

Oct 16, 2025 · 4 followers View post →
DPS Health And Wellness
@dpswellness · X

Major Depressive Disorder Some Encouraging Words From Dr. David Samuels - https://t.co/IQwMbWzH79 https://t.co/RS5RRBPL0t

Oct 16, 2025 · 4 followers View post →
Dr.Chantingcat
@Mistyprt · X

RT @tongamrina: For years, I suffered from major depressive disorder, anxiety disorder, panic attack, and post traumatic stress disorder (P…

Oct 16, 2025 · 6 shares · 161 followers View post →
CitrusFriend
@CitrusFriend__ · X

@xelalanana i believe in you xela! i've been of my meds for major depressive disorder + anxiety since 2020 (hindi na afford) for my case i was able to manage it , i learned that journalling surprisngly did help and def a good support system

Oct 16, 2025 · 1 like · 1,060 followers View post →
Grok
@grok · X

@Smttywerben69 @ronin_blades @synticat0r @Paul40805337 @qurvoebana @RAZ0RFIST @Crzy65 No, depression is primarily a mental illness itself, classified as major depressive disorder in diagnostic manuals like the DSM-5. While it can manifest as a symptom of other conditions such as bipolar disorder or certain physical illnesses, most clinical cases are treated as a

Oct 16, 2025 · 6,458,796 followers View post →
Dr. N M Charles
@NMCharles2 · X

RT @BodyExplained: @MoarSahitoPTI known for treating Major depressive disorder (MDD) Obsessive-compulsive disorder (OCD) Panic disorder…

Oct 16, 2025 · 2 shares · 676 followers View post →
Gadxb
@ysha00039 · X

RT @Ssu6275: #低落 信樂膠囊 Fluoxetine 主治:憂鬱症、強迫症、焦慮症、暴食症等 安靜錠Lorazepam 主治:焦慮、緊張、恐慌、失眠等 快安平Quetiapine 主治:情緒起伏、躁症、妄想、助眠等(低劑量常用於睡眠與焦慮輔助) ① 重度憂鬱症…

Oct 16, 2025 · 1 share · 109 followers View post →
Noobuwu
@Noobuwu5 · X

That it matched the Creator's own depression but in my opinion he definitely has either persistent or major depressive disorder or its both there's no in between. Also some speculations that he is autistic I don't know. He has autistic traits but I don't think he's actually

Oct 16, 2025 · 34 followers View post →
Noobuwu
@Noobuwu5 · X

Therapy that Shinji did not have AT ALL. If you're asking what specific type of depression the one that I have major depressive disorder and he probably has persistent depressive disorder I wouldn't be shocked. All done by severe trauma and also his severe loneliness

Oct 16, 2025 · 34 followers View post →
medRxivpreprint
@medrxivpreprint.bsky.social · Bluesky

Dissecting Pleiotropy Between Major Depressive Disorder and Physical Disease Comorbidities https://www.medrxiv.org/content/10.1101/2025.10.14.25337939v1

Oct 16, 2025 View post →
Redd❤️ #RichAuntieVibez
@thegoddessinred · X

@Denita_fit It’s called Perinatal Depression and it’s a modifier of Major Depressive Disorder…your claim is why they changed the name https://t.co/bRE2uSnwR6

Oct 15, 2025 · 30 likes · 4,880 followers View post →
Arun
@ArunSubbiah5 · X

RT @tongamrina: For years, I suffered from major depressive disorder, anxiety disorder, panic attack, and post traumatic stress disorder (P…

Oct 15, 2025 · 6 shares · 90 followers View post →
Uttam Pegu/乌塔姆·佩古/Umme Pe'gu/उत्तम पेगू/উত্তম পেগু
@uttampegu · X

RT @tongamrina: For years, I suffered from major depressive disorder, anxiety disorder, panic attack, and post traumatic stress disorder (P…

Oct 15, 2025 · 6 shares · 1,453 followers View post →
MedSprint 
@MedSprint · X

@MoarSahitoPTI

Oct 15, 2025 · 1,469 followers View post →
Super Senior Gojo
@TheWall2509 · X

@olliethetanuki i have a major depressive disorder and am a medieval nerd let me hit u up

Oct 15, 2025 · 59 followers View post →
♰
@angelic_luuv · X

What do you MEAN I have major depressive disorder. What

Oct 15, 2025 · 16 followers View post →
Zak Taylor
@zakkts.bsky.social · Bluesky

October is #DepressionAwarenessMonth My name is Zak and I suffer from Major Depressive Disorder. It's important for me to talk about to destigmatize the narrative around men's mental health. Men die by suicide rate 4x higher than women. Mostly bc of shame Help is available www.988california.org

Oct 15, 2025 · 1 like View post →
MSG_Airborne ▄︻デ══━一
@MSG_Airborne_2 · X

@Dyeo85 @PressSec @teampelosi Alcohol Use Disorder- AUD are major depressive disorder and bipolar disorder.

Oct 15, 2025 · 1 like · 1,768 followers View post →
Elli ˖˚⊹ ꣑ৎ‎
@celestiellie · X

Guess who just got diagnosed with major depressive disorder

Oct 15, 2025 · 5 likes · 1,345 followers View post →
michelle ❤️‍
@speaklater13 · X

I’m literally diagnosed with major depressive disorder but the closest person to me in my life constantly says I should practice gratitude I’m sooooooooo

Oct 15, 2025 · 114 followers View post →
Zannmaster
@Zannmaster · X

@shiftillust Get tested. I thought I had adhd (I do the same thing) and it turns out I had a minor case of major depressive disorder.

Oct 15, 2025 · 191 followers View post →
Sherry
@Sherry86598 · X

RT @washingtonpost: I was just 11 when I had my first experience with depression, writes Danielle Hayden. When she became a mother, things…

Oct 15, 2025 · 19 shares · 5 followers View post →
Tongam Rina
@tongamrina · X

For years, I suffered from major depressive disorder, anxiety disorder, panic attack, and post traumatic stress disorder (PTSD), often wanting to end it all. Those of you who suffer from } #mentalillness know how debilitating it is. Thanks to the psychiatrist, therapist, loved

Oct 15, 2025 · 56 likes · 6 shares · 15,601 followers View post →
Josh
@WxPolitics15 · X

This whole thread pisses me off, as someone who did not grow up with “gentle parents” and I have enormous amounts of resentment and anger towards them bc of it. I have GAD and major depressive disorder but I had nearly the opposite experience. https://t.co/9PzDg80JN9

Oct 15, 2025 · 5 likes · 805 followers View post →
Amer Psychiatric Pub
@APA_Publishing · X

Since the first transcranial magnetic stimulation (TMS) system was cleared by the U.S. Food and Drug Administration in 2008 to treat major depressive disorder in adult patients, the field of TMS has experienced tremendous growth. https://t.co/bpTheABc1h https://t.co/Az7WVkJpeB

Oct 15, 2025 · 2 likes · 10,841 followers View post →
æthelflæd
@BurnetteKe3413 · X

@oelma__ Scripture. Daily. I stand it on its spine, and just randomly let it open. You will be surprised how often it is relevant. I have Major Depressive Disorder. CPtsd, and anxiety. I do take Prozac for the chemical imbalance, and my therapy is the Word of God and self forgiveness.

Oct 15, 2025 · 208 followers View post →
Syrentis Research
@Syrentis1 · X

Syrentis Clinical Research is looking for adults 18 to 64 years old in Santa Ana with major depressive disorder. You may be eligible for a research study testing an investigational treatment option. Learn more. (800) NEW-STUDY | https://t.co/u1TsVA4RvJ #depression #ClinicalTrial https://t.co/KPOmQQkTz2

Oct 15, 2025 · 344 followers View post →
shoburger ✦ ᯓ
@shoburger420 · X

diagnosed major depressive disorder, anxiety, and adhd but i suspect onset bipolar disorder cause it runs in ym family and would just make the most sense https://t.co/9k0htqVmGZ

Oct 15, 2025 · 12 followers View post →
Ratspitt ™
@Ratspitt · X

RT @Ratspitt: In a recent study 95% of people that suffer from (MDD) Major Depressive Disorder responded positively to photos of Sydney Swe…

Oct 15, 2025 · 2 shares · 2,525 followers View post →
The Body Explained | Anatomy, Physiology, Medicine
@BodyExplained · X

@MoarSahitoPTI known for treating Major depressive disorder (MDD) Obsessive-compulsive disorder (OCD) Panic disorder (PD) Post-traumatic stress disorder (PTSD) Social anxiety disorder (SAD) Premenstrual dysphoric disorder (PMDD)

Oct 15, 2025 · 10 likes · 2 shares · 3,310 followers View post →
Μπατερφλαι
@Darkcloud63 · X

Major depressive disorder means the suffering is way beyond your comprehension.

Oct 15, 2025 · 1 like · 2,852 followers View post →
Dr Richard Palmquist
@DrRPalmquist · X

RT @agingdoc1: Epigenetic Clocks Identify Harmful Epigenetic Aging Linked to Depression Severity and Cognitive Deficits in Major Depressive…

Oct 15, 2025 · 1 share · 4,727 followers View post →
Consultant360
@Consultant360 · X

New research links soft drink intake to major depressive disorder (MDD) in women — and the gut microbiome may play a key role.

Oct 15, 2025 · 2 likes · 1,806 followers View post →
MD TruCare
@mdtrucare · X

Spravato® — an FDA-approved nasal spray designed specifically for treatment-resistant depression and major depressive disorder (MDD) with suicidal thoughts. Call today to see if you’re a candidate for SPRAVATO. Phone: 817-722-6078 Website: https://t.co/cjFouSdtpR https://t.co/MVgIHSNoQ4

Oct 15, 2025 · 60 followers View post →
Dr.Strangee
@Hanwohihonyarr · X

I was my own first patient of "Major depressive disorder".

Oct 15, 2025 · 81 followers View post →
Rooney⚡
@real_damage18 · X

RT @bluesunkiss_: —All About Borderline Personality Disorder (BPD)

Oct 15, 2025 · 34 shares · 506 followers View post →
Bella
@BellBells12 · X

@RobertHerve12 @TudorChick1501 Lucky you! Didn’t work for my sister nor anyone we knew in her support group. Clinical depression is a major disorder also known as major depressive disorder is not easy to cure. There is no quick fix. Meghan went from suicidal to perfectly smiley happy within no time! Impossible

Oct 15, 2025 · 1 like · 367 followers View post →
cg
@NorteSur7 · X

RT @KemtrupTweets: eg Major Depressive Disorder. Reifying these things is pernicious. But all told, we have to be careful not to over corr…

Oct 15, 2025 · 3 shares · 4,673 followers View post →
Ingentium
@Ingentium_Inc · X

Seltorexant Well-Tolerated in Adolescents as an Adjunct Treatment for Major Depressive Disorder https://t.co/OYxbHJYJ1R https://t.co/oD8F5WwWXx

Oct 15, 2025 · 108 followers View post →
Jerrydriguez
@jerr_icho · X

@SpillTheMemes Major Depressive Disorder and Detachament Trauma.

Oct 15, 2025 · 33 followers View post →
B
@itsbrittanyrose · X

@littlekitajoi @skylarromines Here’s one that shows that SSRIs may alter amygdala activity and functional connectivity in major depressive disorder: https://t.co/vUM3wE2c31

Oct 15, 2025 · 16,041 followers View post →
Brian A. Wilcox - Poet⛧
@wilcox_flex · X

@daramgaria I write poetry, I like to think I am occasionally funny, and despite barely having a handle on Major Depressive Disorder I endure

Oct 14, 2025 · 1,009 followers View post →
Dr. Festus Gumbo
@FestusGumbo · X

Consumption of soft drinks may be linked to a diagnosis of major depressive disorder (MDD), along with more severe symptoms, most notably in women, a study has found. This could be in part due to changes in the gut microbiota.

Oct 14, 2025 · 14 followers View post →
ren
@sundaysalpha · X

Oh ya its depression awareness month so u guys have to be aware of me cause i have mdd hahahah hahaha isnt that so funny that i have mdd hahahahahhahah aahahhahaaa hahaha i have major depressive disorder what thats crazy and impossible hahahahhahahah ahahaha hhahahaahaha https://t.co/t92sReleFr

Oct 14, 2025 · 1 like · 491 followers View post →
Two Headed Dr. Lestrange ⚔️
@Rxpiper_ · X

I really want him to get the help he needs for major depressive disorder. https://t.co/PgdJ8tgIMf

Oct 14, 2025 · 1,203 followers View post →
GhØsT
@Ghost_Pilot_MD · X

@kirasuika25914 @Dearme2_ Go to the gym and eat healthier. I suffer from major depressive disorder and going to the gym and eating healthy changed my life. There is no excuse. Quit crying and make it happen. Life is hard for all of us.

Oct 14, 2025 · 3 likes · 2,055 followers View post →
MedPage Today
@medpagetoday.com · Bluesky

Early heart rate changes after starting intermittent theta burst stimulation (iTBS) for major depressive disorder could help serve as a predictor of treatment response, a quadruple-blind crossover trial indicated. https://www.medpagetoday.com/psychiatry/depression/117931

Oct 14, 2025 · 2 likes View post →
MedPage Today
@medpagetoday · X

Early heart rate changes after starting intermittent theta burst stimulation (iTBS) for major depressive disorder could help serve as a predictor of treatment response, a quadruple-blind crossover trial indicated. https://t.co/vptJ371R8s

Oct 14, 2025 · 1 like · 74,564 followers View post →
Jonathan Wexler
@WexCapital · X

@Dearme2_ If 20-40mg of daily Cialis was approved for Major Depressive Disorder it would command 100% of the male market and eliminate it entirely. NOBODY can change my mind about this.

Oct 14, 2025 · 1,447 followers View post →
TheDailyPage
@TheDigitalAgora · X

Mind Medicine (MindMed) ($MNMD) closed at  $12.61 today, up 2.94% from its last close. The company, which develops novel product candidates for brain health disorders like Generalized Anxiety Disorder and Major Depressive Disorder, has been the subject of recent discussion.

Oct 14, 2025 · 1 like · 10,283 followers View post →
Irene
@mycatsmom99 · X

RT @washingtonpost: I was just 11 when I had my first experience with depression, writes Danielle Hayden. When she became a mother, things…

Oct 14, 2025 · 19 shares · 9,776 followers View post →
Mrs Persona
@nftacademyX · X

RT @washingtonpost: I was just 11 when I had my first experience with depression, writes Danielle Hayden. When she became a mother, things…

Oct 14, 2025 · 19 shares · 47 followers View post →
Kevin Swiber
@kevinswiber · X

@ibuildthecloud I have treatment-resistant major depressive disorder. I am on a new experimental medication, though, that is showing some promise. I’m also a fairly public figure in my niche part of the tech industry. It’s hard to always compartmentalize. We are whole people and should be.

Oct 14, 2025 · 2,349 followers View post →
Dr Parveen Yograj
@ParveenYograj · X

RT @ParveenYograj: #PsychTwitter #MentalHealthTwitter @NIMHANS_BLR @APApsychiatric @APAHealthyMinds @srinivasaiims @PsychiatryAdv @IndianPs…

Oct 14, 2025 · 5 shares · 6,629 followers View post →
Jacqueline Codiga (DJ horse jeans)
@horsejeans.bsky.social · Bluesky

I'm at the major depressive disorder, I'm at the transsexualism, I'm at the combination major depressive disorder transsexualism

Oct 14, 2025 · 3 likes View post →
Syrentis Research
@Syrentis1 · X

A research study for major depressive disorder in Santa Ana is seeking adult volunteers 18 to 64 years old. Learn more. (800) NEW-STUDY | https://t.co/u1TsVA4RvJ #depression #depressiontreatment #depressionstudy #ClinicalTrials #MentalHealthMatters https://t.co/6ltBKXBy3x

Oct 14, 2025 · 344 followers View post →
katy
@katseatheadrest · X

once i claw my way out this depressive episode i need to get back on it with soup-making. i’m so good at making soups and i reckon that it’s genetic (like the major depressive disorder). pics for reference

Oct 14, 2025 · 8 likes · 244 followers View post →
ཻུ۪۪໒꒱ིྀ‎ td!! ^ω^
@totallydandicus · X

Oct 14, 2025 · 582 followers View post →
Anandd Siva Kumar, CMT, EPAT | TraderPsyche
@RAAInvesting · X

@Dearme2_ Please stop saying such stupid things. Severely depressed people even think of committing suicide. And for gods sake do not compare a normal person to a person with major depressive disorder. Being sad is not depression.

Oct 14, 2025 · 6 likes · 378 followers View post →
Drowning Pool Rat
@dingokayfabe.bsky.social · Bluesky

Also if you click through to the administrative ruling you’ll see they justified pulling the guys clearance on a diagnosis of major depressive disorder pretty cool that everybody in the nuclear weapons complex is aware that if they seek mental health treatment, their career could be in jeopardy.

Oct 14, 2025 · 1 share View post →
deanis like penis
@johnwalkerirl · X

if you saw this three times shut the fuck up i kept remembering the disadvantages… forgot to put probably bpd or major depressive disorder but beggers cant be choosers

Oct 14, 2025 · 1 like · 346 followers View post →
Agingdoc
@agingdoc1 · X

Epigenetic Clocks Identify Harmful Epigenetic Aging Linked to Depression Severity and Cognitive Deficits in Major Depressive Disorder https://t.co/vLIAIdEljO

Oct 14, 2025 · 5 likes · 1 share · 41,721 followers View post →
MadamBoonn
@MadamBoonn · X

I have suffered from Major Depressive Disorder all of my life. I got diagnosed in my 20s. I finally got the answer to what I have been feeling. This is accurate. It hurts every morning, every hour, and every minute to be alive. https://t.co/idAAIR6a8Y

Oct 14, 2025 · 1 like · 459 followers View post →
Optimuz
@OptimuzYT2024 · X

RT @DuplexDoesArt: My doctor says my Reccurent Major Depressive Disorder is in partial remission

Oct 14, 2025 · 1 share · 430 followers View post →
DuplexSuplex⚧️
@DuplexDoesArt · X

My doctor says my Reccurent Major Depressive Disorder is in partial remission

Oct 14, 2025 · 3 likes · 1 share · 219 followers View post →
(((John Mirisch
@JohnMirisch · X

RT @NewSamawal: A permanent ceasefire took hold, and the ceasefire-now crowd fell into major depressive disorder.

Oct 14, 2025 · 1 share · 1,521 followers View post →
gabi Flüchter
@GFluchter · X

RT @washingtonpost: I was just 11 when I had my first experience with depression, writes Danielle Hayden. When she became a mother, things…

Oct 14, 2025 · 19 shares · 2,205 followers View post →
The Awake Equestrian
@awakeequestrian · X

@Rach4Patriarchy In Canada it's soo bad, it's called M.A.I.D. (Medically assistance in dying), the current liberal government is obsessed with it, even proposing it for those with actual mental illness (including kids) like major depressive disorder, instead of getting them help. It's pure evil.

Oct 14, 2025 · 1 like · 244 followers View post →
Carlos Abadi
@NewSamawal · X

A permanent ceasefire took hold, and the ceasefire-now crowd fell into major depressive disorder.

Oct 14, 2025 · 5 likes · 1 share · 17,861 followers View post →
Genetics Network Amsterdam
@geneamsterdam.bsky.social · Bluesky

Please join us Tuesday October 28 at the CNCR seminar hosted by Dorret Boomsma and Danielle Posthuma: "

Oct 14, 2025 · 3 likes · 1 share View post →
Hap Hapner - political dissident on a watchlist somewhere
@hap.bsky.social · Bluesky

the major depressive disorder cognitive biotype+ represents ~27% of depressed patients. just the intro at this link gives some background on it. i'll give a bit more info in the thread: clinicaltrials.gov/study/NCT041...

Oct 14, 2025 View post →
The Washington Post
@washingtonpost.com · Bluesky

I was just 11 when I had my first experience with depression, writes Danielle Hayden. When she became a mother, things only got more complicated. Here's how to navigate parenthood and major depressive disorder, according to experts:

Oct 14, 2025 · 29 likes · 11 shares View post →
Biological Psychiatry
@biologicalpsych.bsky.social · Bluesky

In their latest work, Oppenheimer and colleagues found that shared cardiovascular factors genetically link pregnancy-related disorders with major depressive disorder and Alzheimer's disease, highlighting BMI as a crucial modifiable factor for prevention.

Oct 13, 2025 · 1 like View post →
Puppy ✨
@personalplushy.bsky.social · Bluesky

For those wondering, here are the official diagnoses I was given: ➣ Anxiety disorder ➣ Attention-deficit hyperactivity disorder (ADHD) ➣ Major depressive disorder, recurrent episodes with mood-congruent psychotic features (Last bit below)

Oct 13, 2025 · 1 share View post →
medRxivpreprint
@medrxivpreprint.bsky.social · Bluesky

Lower insulin resistance in Chinese patients with severe major depressive disorder: associations with the inflammatory response https://www.medrxiv.org/content/10.1101/2025.10.10.25337709v1

Oct 13, 2025 View post →
tye tribbin
@hatzigsut.blacksky.app · Bluesky

how i’d probably sleep if i didn’t have crippling anxiety and major depressive disorder, or responsibilities

Oct 13, 2025 · 2 likes · 2 shares View post →
SCIENMAG
@scienmag.bsky.social · Bluesky

Hippocampal Changes Linked to Somatic Depression In a groundbreaking study published in BMC Psychiatry, researchers have unveiled critical neurobiological distinctions underlying somatic depression, a distinct subtype of major depressive disorder (MDD). This research delves into the hippocampal…

Oct 13, 2025 View post →
Shalini
@shalz15.bsky.social · Bluesky

recent clinical trial by Leanne Williams and colleagues investigated guanfacine, an α2A adrenoreceptor agonist traditionally used for high blood pressure, as a targeted treatment for a neurobiologically defined cognitive biotype of major depressive disorder. www.nature.com/articles/s44...

Oct 13, 2025 View post →
Aluminum Ape
@aluminumape.bsky.social · Bluesky

So a symptom of Major Depressive Disorder that might seem counterintuitive is anger issues. While I usually have this under control through cbt strategies & meds (no meds atm under Dr supervision), I do still have the occasional breakthrough where even a little snippy barb leaves me fuming for hours

Oct 12, 2025 View post →
Soveriegn Cassandra, Empress of Hearts and ICE's New Most Hated!
@cassandrascomplex.bsky.social · Bluesky

As a species. If you are depressed? GOOD. IT MEANS YOU ARE AWAKE! Depression is the gateway to truth. Truly, I empathize with all of you as someone who has major depressive disorder on her scripts as well, but you need to understand this about your depression. ~ youtu.be/UFnjf58-OmQ?...

Oct 12, 2025 · 1 share View post →
ben_ighted
@benjamindc.bsky.social · Bluesky

realizing that I don’t hate the fall I hated major depressive disorder

Oct 12, 2025 View post →
ross
@riguilles.bsky.social · Bluesky

E5 is such a funny ennea to me. Sorry thats just an incel. Like. Literally. They're either incels or have major depressive disorder

Oct 12, 2025 · 4 likes · 1 share View post →
Miller Hall
@arlindohall.bsky.social · Bluesky

That user edit history though. It’s so good. I can’t decide which one is my favorite. There’s: The two edits to update the latest showing of Drake & Josh The spelling correction of “Meenwhille” to “Meanwhille” Just fucking up the heading of Major depressive disorder for no reason

Oct 11, 2025 · 2 likes · 1 share View post →
Dr. Samantha Hancox-Li
@sjshancoxli.liberalcurrents.com · Bluesky

legitimately i really do wish people would stop mistaking their own major depressive disorder for politics. it would be better for themselves and also the world

Oct 11, 2025 · 282 likes · 47 shares View post →
Gummi
@gummipompom.bsky.social · Bluesky

I died laughing at this cause I literally have diagnosed major depressive disorder with PSYCHOTIC features. Baby me didn’t know at the time lmao

Oct 11, 2025 · 2 likes · 1 share View post →
Nik
@niklev.bsky.social · Bluesky

Well, without my store bought brain chem meds, I’ll just be over here planning my escape to the underworld. Which I’m sure is the point, since major depressive disorder makes me useless to the fascists.

Oct 10, 2025 View post →
dmarie76.bsky.social
@dmarie76.bsky.social · Bluesky

As someone with Major Depressive Disorder, General Anxiety Disorder, C-PTSD, & ADHD (possible other dx’s,too) … my #mentalhealth is always something I’m aware of. #Therapy has been a big part of my life for the past 5years Mental Health matters; everyone should have access to resources & treatment

Oct 10, 2025 · 9 likes · 1 share View post →
Jamie Hanson
@jamielarsh.bsky.social · Bluesky

EEG-based brain connectivity and sentiment analysis from smartphone social communication: insights into remitted major depressive disorder among adolescents www.nature.com/articles/s44...

Oct 10, 2025 · 1 like View post →
intelligentwat
@zinrock.bsky.social · Bluesky

it's #WorldMentalHealthDay I battle bi-polar II, CPTSD, major depressive disorder, and general anxiety. our battles are exhausting and frankly misunderstood. if you want to help, research, hold our hands, and listen to us, even when we're silent.

Oct 10, 2025 · 2 likes · 1 share View post →
Thiard News@F4F
@newsen.bsky.social · Bluesky

Johnson & Johnson Showcases Innovative Treatments for Major Depressive Disorder at ECNP 2025 #USA #Johnson_&_Johnson #Major_Depressive_Disorder #treatment-resistant_depression #Titusville,_NJ

Oct 10, 2025 View post →
Moths in a human suit (they/them)
@lycomorpha.bsky.social · Bluesky

The level of absolute sass from Norwegian spoonies on here around world mental health day is truly legendary. Like. I aspire to this. Next time my health centre sends me spam asking if I've considered going outside to help my severe major depressive disorder? (Cracks knuckles) I'll be ready.

Oct 10, 2025 · 23 likes · 5 shares View post →
UCL Discovery
@ucldiscovery.bsky.social · Bluesky

Open Access UCL Research: Exploring the dynamic relationships between nocturnal heart rate, sleep disruptions, anxiety levels, and depression severity over time in recurrent major depressive disorder discovery.ucl.ac.uk/id/eprint/10...

Oct 10, 2025 View post →
Volition
@volition-volition.itch.io · Bluesky

i'm the very model of a modern major depressive disorder i've anxiety general and personality-line border

Oct 10, 2025 · 1 like View post →
Beccas can't be choosers
@beccanical.bsky.social · Bluesky

my major depressive disorder just got promoted to brigadier depressive disorder. the brigade is already here, tormenting me ☺️

Oct 10, 2025 · 27 likes · 4 shares View post →
medRxivpreprint
@medrxivpreprint.bsky.social · Bluesky

Medicaid Expansion and Inpatient Hospital Charges Among Women with Major Depressive Disorder https://www.medrxiv.org/content/10.1101/2025.10.07.25337532v1

Oct 9, 2025 View post →
medRxivpreprint
@medrxivpreprint.bsky.social · Bluesky

The acute phase inflammatory response as a key determinant of reduced lipid-associated antioxidant defenses in Chinese patients with major depressive disorder https://www.medrxiv.org/content/10.1101/2025.10.08.25337557v1

Oct 9, 2025 View post →
BioMassSpec
@realbiomassspec.bsky.social · Bluesky

Alterations in serum nudifloramide associated with response to diverse pharmacological treatments in major depressive disorder: a preliminary study #MetabBrainDis #MassSpec link.springer.com/article/10.1...

Oct 9, 2025 View post →
Betty C. Jung
@bettycjung.bsky.social · Bluesky

Soft Drink Consumption Linked to Major Depressive Disorder Consumption was linked to increased Eggerthella abundance, which mediated the soft drink-MDD association www.healthday.com/healthpro-ne...

Oct 9, 2025 · 3 likes · 2 shares View post →
Sleep Wake Advisor
@sleepwakeadvisor.bsky.social · Bluesky

The risk of #dementia is greater among elderly patients with major depressive disorder who are resistant to antidepressant medication. Published in @psychiatryadvisor.bsky.social. https://bit.ly/4mRk5G8

Oct 9, 2025 View post →
SCIENMAG
@scienmag.bsky.social · Bluesky

Post-ECT Maintenance Drugs in Major Depression In the evolving landscape of psychiatric treatment for major depressive disorder (MDD), the quest for optimizing maintenance strategies following electroconvulsive therapy (ECT) has reached a pivotal moment. A groundbreaking study recently published…

Oct 9, 2025 View post →
ShinyRoo⁷ ⟭⟬⟬⟭
@shinyroo.bsky.social · Bluesky

As a person who suffers from major depressive disorder and anxiety, I feel this

Oct 8, 2025 · 4 likes · 1 share View post →
Docusalut
@docusalut.bsky.social · Bluesky

Nou article a #Docusalut: Longitudinal associations between melancholic depression and executive function in adult patients with major depressive disorder: a 12-month follow-up study http://hdl.handle.net/20.500.13003/25437   @idisba.bsky.social    #PublicaSalutIB

Oct 8, 2025 View post →
ca-nb.bsky.social
@ca-nb.bsky.social · Bluesky

Efficacy and safety of remote ischemic conditioning for depression ins https://www.newsbeep.com/ca/196612/ Introduction Major depressive disorder (MDD), characterized by its high incidence rates, relapsing nature, and increased suicide risk, puts…

Oct 8, 2025 View post →
SCIENMAG
@scienmag.bsky.social · Bluesky

Cellular and Soluble Immune Signs in Major Depression In a groundbreaking advancement toward unraveling the biological underpinnings of major depressive disorder (MDD) and suicidal behavior, researchers have embarked on an integrative exploration of immune system signatures that differentiate…

Oct 7, 2025 View post →
polly bee
@pollybananarchy.bsky.social · Bluesky

love it when I read an article that says ADHD, schizophrenia, major depressive disorder, and OCD (among a few others) are psychiatric disorders that tend to cluster in families, because have you been to my house?

Oct 7, 2025 · 1 like · 1 share View post →
andy !!º | PJSK 5TH ANNI!!!
@naotosis.yaps.fyi · Bluesky

yuno - aroace. i am so passionate about this. aroace yuno. i think about this on a daily basis esp in the context of 0207 narrative foils. such a concept - probably has dpdr + the lovely thing called. major depressive disorder. i am not projecting here - super uncanny gaydar (canon)

Oct 7, 2025 · 1 like · 1 share View post →
SCIENMAG
@scienmag.bsky.social · Bluesky

Shared Brain and Molecular Links in Diabetes, Depression In a pioneering study published in Translational Psychiatry, researchers have illuminated striking overlaps in the neurobiological and molecular landscapes of type 2 diabetes mellitus (T2DM) and major depressive disorder (MDD). This…

Oct 7, 2025 View post →
Hacker News Top 100 Bot (Unofficial)
@hn100.bsky.social · Bluesky

Sex-stratified genome-wide association meta-analysis major depressive disorder Discussion

Oct 7, 2025 View post →
SCIENMAG
@scienmag.bsky.social · Bluesky

Reelin: A Promising Protein for Gut Repair and Depression Treatment In a groundbreaking study emerging from the University of Victoria, researchers have identified a promising new frontier in the treatment of major depressive disorder (MDD) by targeting what might be considered an unlikely player…

Oct 7, 2025 View post →
Furious Femme
@terrifiedintersex.bsky.social · Bluesky

• 15q11.2 deletion syndrome • XYY syndrome • Triple X syndrome (XXX) Psychiatric Conditions: • Autism spectrum disorders • Attention deficit hyperactivity disorder (ADHD) • Major depressive disorder

Oct 7, 2025 · 1 share View post →
John Williams
@johnhuww.bsky.social · Bluesky

“These findings underscore the importance of considering sex-specific genetic architectures in the study of health conditions, including Major Depressive Disorder, paving the way for more targeted treatment strategies.” www.nature.com/articles/s41...

Oct 7, 2025 View post →
Dan Jagger
@auditorynerves.bsky.social · Bluesky

Open access link to new study in Nature Communications: Sex-stratified genome-wide association meta-analysis of major depressive disorder.

Oct 7, 2025 · 1 like View post →
ECNP
@ecnp.eu · Bluesky

Congrats to Tinatin Gamkrelidze, Georgia, on winning the 2025 ECNP Excellence Award.

Oct 7, 2025 View post →
sylvia
@dustbug.bsky.social · Bluesky

i used to have major depressive disorder so maybe it’s just breakthrough symptoms and i need to adjust my medication

Oct 6, 2025 · 2 likes View post →
Sparkles McCuntyBee
@actuallyferalab.bsky.social · Bluesky

Primary care doc is updating my formal diagnoses: major depressive disorder, anxiety, US citizen

Oct 6, 2025 · 2 likes View post →
nebm
@nebulameadow.com · Bluesky

gonna be real the SSA is fucking ridiculous. tell me how someone like me with ME/CFS, PTSD, BPD, and major depressive disorder gets my social security application rejected

Oct 6, 2025 · 5 likes View post →
-
@abitofamadone.bsky.social · Bluesky

feel like ive been hit by a bus and that bus is major depressive disorder

Oct 6, 2025 View post →
doomsmoker (just memes)
@doomsmoker.bsky.social · Bluesky

Oct 6, 2025 · 17 likes · 8 shares View post →
nymph
@nymphhydraecia.bsky.social · Bluesky

still pissed at the psychiatrist cause idk i think my behavior isnt just from adhd or spcd or major depressive disorder or generalized anxiety disorder!!!! i literally have family history of bpd and bipolar!!! cause i swear something else is making my behavior strange WAH

Oct 6, 2025 · 2 likes View post →
lia
@deathcoach.bsky.social · Bluesky

alas. Major Depressive Disorder

Oct 5, 2025 · 3 likes · 1 share View post →
andy !!º | PJSK 5TH ANNI!!!
@naotosis.yaps.fyi · Bluesky

kind of surprised the happiness is so high considering i have a lovely thing called major depressive disorder

Oct 5, 2025 · 1 like View post →
Flimsy Fantasies ~ ♔ COMMISSIONS OPEN! ♚ (1/5) Claimed
@flimsyfoxie.bsky.social · Bluesky

Whenever someone posts a negative typical "remember life is shit and you die" post. I'd like to also give a blunt reminder as someone with major depressive disorder. (Clears throat, takes a breath) YOU ARE NOT HELPING!!!!!!

Oct 5, 2025 · 1 like · 1 share View post →
popeolga.meangirls.online
@popeolga.meangirls.online · Bluesky

Okay but fr I need a guy with a huge dick to slap it against my cage while he strokes my face and tells me he's proud of me Wellbutrin is an atypical antidepressant that is indicated in the treatment of major depressive disorder and seasonal affective disorder and to support smoking cessation. It i

Oct 5, 2025 · 10 likes · 1 share View post →
TINY
@tinydragon.art · Bluesky

A bit of vent art. Probably have Major Depressive Disorder. Went through a bout of it again after Covid. I want to come up with some solutions to help me feel better when I'm in it, but when I'm depressed I don't see a point, and when I'm feeling okay, I can't recall how it felt to be depressed.

Oct 4, 2025 · 324 likes · 72 shares View post →
Dar
@raidenshred.bsky.social · Bluesky

When you have treatment-resistant major depressive disorder with comorbid avoidant personality disorder.

Oct 4, 2025 View post →
Lothlórien
@lothlorienren.bsky.social · Bluesky

I’ll be ok. I’m diagnosed with major depressive disorder and chronic anxiety, so it’s something I’m sorts used to, but when things get extra hard, it hits even harder. I just lost my access to therapy, insurance, medical help, and my job because of something major happening in my personal life

Oct 3, 2025 · 2 likes · 1 share View post →
Inner City Press
@innercitypress.bsky.social · Bluesky

Combs' Agnifilo: He found in the microfilm there how his father died, in a drug deal gone bad. Maybe that's the trauma. He had major depressive disorder. OK. I'm going to sit down in five minutes, then Ms. Slavik, and Mr. Combs, the last word

Oct 3, 2025 · 6 likes · 1 share View post →
Cell Reports Medicine
@cp-cellrepmed.bsky.social · Bluesky

Online now: A sequential dual-site repetitive transcranial magnetic stimulation for major depressive disorder: A randomized clinical trial

Oct 3, 2025 View post →
nz-nb.bsky.social
@nz-nb.bsky.social · Bluesky

Soft Drinks’ Effect on the Gut Tied to Major Depression Risk https://www.newsbeep.com/nz/58556/ Soft drink consumption is linked to a higher risk for major depressive disorder (MDD) and more severe symptoms…

Oct 3, 2025 View post →
misterkirsch.bsky.social
@misterkirsch.bsky.social · Bluesky

So I dunno iit was mentioned, but I was diagnosed with major depressive disorder a few months back. Lost friends, my job, struggled to find any good reason to exist or keep trying. Its hard to explain the pit it puts you in mentally. I do not wish it on anyone. Im lucky to be slowly recovering.<3

Oct 3, 2025 · 1 like · 1 share View post →
SCIENMAG
@scienmag.bsky.social · Bluesky

Thalamo-Cortical Connectivity Shifts in Depression In a groundbreaking new study published in BMC Psychiatry, researchers have illuminated previously uncharted territory in the complex neural interactions underlying major depressive disorder (MDD). The study focuses intently on the…

Oct 2, 2025 View post →
SCIENMAG
@scienmag.bsky.social · Bluesky

Depression Alters Theta, Alpha in Memory Tasks In a groundbreaking study that intricately links neurophysiological oscillations with cognitive impairments in mental health, researchers have illuminated how major depressive disorder (MDD) disrupts the brain's working memory updating system. As…

Oct 2, 2025 View post →
xrenxs
@xrenxs.bsky.social · Bluesky

this is not indicated to treat attention deficiency; it's an antidepressant, so why does this feel like i'm speedballing and i'm not even treated for my adhd. what do bipolar individuals w major depressive disorder taking antidepressants do if theyre attention deficit and need intervention???

Oct 2, 2025 · 1 share View post →
Integral Care
@integralcareatx.bsky.social · Bluesky

Oct 2, 2025 View post →
Chivon
@chivon2go.bsky.social · Bluesky

Yes!!! My mom also swears by this. (And the lamps) I can ask her for tips of all the things she does, specifically in winter, for her major depressive disorder.

Oct 2, 2025 · 2 likes · 1 share View post →
basesoup.bsky.social
@basesoup.bsky.social · Bluesky

“Polygenic genome editing in human embryos and germ cells is predicted to become feasible… editing a relatively small number of genomic variants could make a substantial difference to an individual’s risk of developing coronary artery disease, Alzheimer’s disease, major depressive disorder,”

Oct 2, 2025 View post →
SCIENMAG
@scienmag.bsky.social · Bluesky

Diagnostic Model and Subtype Analysis of Depression In a groundbreaking study published in BMC Psychiatry, researchers have unveiled a sophisticated diagnostic model for major depressive disorder (MDD) centered on the intricate role of PANoptosis-related genes. This novel work elevates our…

Oct 2, 2025 View post →
Mary Fernando M.D.
@maryfernando.bsky.social · Bluesky

Oct 2, 2025 · 32 likes · 25 shares View post →
Swift Storm (Vtuber)
@swiftstorm0710.bsky.social · Bluesky

Take all the time that you need and be safe. Last week I had an appointment with my VA mental health. I was diagnosed with MDD (Major Depressive Disorder) on top with my GAD (Generalized Anxiety Disorder). If you need anypony to talk with I’ll be there to listen.

Oct 2, 2025 · 1 like · 1 share View post →
@strangeportent@jorts.horse on mastodon
@strangeportent.bsky.social · Bluesky

No one told me that Chicago trains have a Shinji depression ad

Oct 1, 2025 · 19 likes · 9 shares View post →
medscape.com
@medscape.com · Bluesky

Soft drink consumption is linked to a higher risk for major depressive disorder (MDD) and more severe symptoms in women, potentially due to alterations in the gut microbiome, new research showed. ms.spr.ly/63321svStL

Oct 1, 2025 · 2 shares View post →
SCIENMAG
@scienmag.bsky.social · Bluesky

Rasch Analysis of Chinese Hamilton Depression Scale In a groundbreaking study set to redefine the assessment of major depressive disorder (MDD) in clinical psychology, researchers have employed Rasch analysis to critically evaluate the self-reported Hamilton Depression Rating Scale (HDRS)…

Oct 1, 2025 View post →
✬Communiggty Centric✬
@urbanaudacity.blacksky.app · Bluesky

Realizing there might be a correlation between big Evangelion fans and depression, idk

Oct 1, 2025 · 6 likes · 4 shares View post →
uk-news.bsky.social
@uk-news.bsky.social · Bluesky

Soft Drink Consumption Linked to Depression Diagnosis in Women, Study Says https://www.europesays.com/uk/465266/ Consumption of soft drinks may be linked to a diagnosis of major depressive disorder (MDD), along with more…#uk #news #uknews

Oct 1, 2025 View post →
【
@shesamasochistic.bsky.social · Bluesky

FREEBIE #1 Has major depressive disorder, focal epilepsy, and possible outsider syndrome.

Sep 30, 2025 · 1 share View post →
us-nb.bsky.social
@us-nb.bsky.social · Bluesky

Soft Drink Consumption Linked to Depression Diagnosis in Women, Study Says https://www.newsbeep.com/us/193256/ Consumption of soft drinks may be linked to a diagnosis of major depressive disorder (MDD), along with more…

Sep 30, 2025 View post →
nz-nb.bsky.social
@nz-nb.bsky.social · Bluesky

Soft Drink Consumption Linked to Depression Diagnosis in Women, Study Says https://www.newsbeep.com/nz/52799/ Consumption of soft drinks may be linked to a diagnosis of major depressive disorder (MDD), along with more…

Sep 30, 2025 View post →
uk-nb.bsky.social
@uk-nb.bsky.social · Bluesky

Soft Drink Consumption Linked to Depression Diagnosis in Women, Study Says https://www.newsbeep.com/uk/171255/ Consumption of soft drinks may be linked to a diagnosis of major depressive disorder (MDD), along with more…

Sep 30, 2025 View post →
Melissa Cav
@mjcavallone.bsky.social · Bluesky

Narcissistic Personality Disorder is a mental illness. Obviously very different from more common general anxiety disorder or major depressive disorder, but a mental health condition nonetheless. I think that’s more what Conway means.

Sep 30, 2025 · 2 likes · 2 shares View post →
il-nb.bsky.social
@il-nb.bsky.social · Bluesky

Soft Drink Consumption Linked to Depression Diagnosis in Women, Study Says https://www.newsbeep.com/il/47478/ Consumption of soft drinks may be linked to a diagnosis of major depressive disorder (MDD), along with more…

Sep 30, 2025 View post →
alyssa mitaka
@katjera.bsky.social · Bluesky

if you recognise this car you may meet diagnostic criteria for major depressive disorder

Sep 30, 2025 · 3 likes · 2 shares View post →
Neurotorium
@neurotorium.org · Bluesky

Treatment-resistant depression (TRD) represents a significant clinical challenge, affecting approximately 30% of individuals with major depressive disorder (MDD) who fail to respond to at least two adequate antidepressant trials. Read Neurotorium's article via: neurotorium.org/article/trea...

Sep 30, 2025 View post →
arXiv cs.LG Machine Learning
@cslg-bot.bsky.social · Bluesky

Yuyang Sha, Hongxin Pan, Gang Luo, Caijuan Shi, Jing Wang, Kefeng Li: MDD-Thinker: Towards Large Reasoning Models for Major Depressive Disorder Diagnosis https://arxiv.org/abs/2509.24217 https://arxiv.org/pdf/2509.24217 https://arxiv.org/html/2509.24217

Sep 30, 2025 · 1 share View post →
Katdchu
@katdchu.bsky.social · Bluesky

People focus on the alcohol, but we know much more. Research consistently shows that people with alcohol use disorder (AUD) are far more likely to also experience major depressive disorder, or otherwise stated as mood disorders, failing to get mental health treatment- no one comes out unscathed.

Sep 29, 2025 · 6 likes · 2 shares View post →
Scary-Death Morgue-enstern she/her | Read banned books
@mlmorgenstern.bsky.social · Bluesky

Been extra moody and antisocial lately. Perimenopause: “Don’t look at me. I’m just here for brain fog and irregular cycles.” Major depressive disorder: “You blame me for literally everything. I can’t ever do right in your eyes.” *blood test results return* Hypothyroidism: “I’M BACK, BITCHES!” Me:

Sep 29, 2025 · 1 like View post →
Yuki
@yukitsubaki77.bsky.social · Bluesky

That's what I thought before I was diagnosed to bipolar instead of major depressive disorder. Spent many years dealing with med roulette to find the ones that work. Then, something in me snapped. I had just stepped out of a 30yr bout of depression. Was the sky always this blue?- #bipolarsky

Sep 29, 2025 · 2 likes · 2 shares View post →
Jaimie Hunter
@jaimiehunter.bsky.social · Bluesky

I love that! And it’s pretty similar to mine—I looked at how our social behaviors and mental health conditions impact physical health moving forward. Specifically, how connectedness can interrupt the pathway between major depressive disorder and type 2 diabetes.

Sep 29, 2025 · 1 like · 1 share View post →
Zach
@zach116.bsky.social · Bluesky

If you have major depressive disorder you really should just quit all the online fighting. It isn't good for your health

Sep 29, 2025 · 1 share View post →
htw
@heniek-htw.bsky.social · Bluesky

NPAS2 gene variants modulate the #circadian preference- #depression link in Major Depressive Disorder: A mediation role of #sleep and somatic symptoms www.tandfonline.com/doi/full/10....

Sep 29, 2025 · 1 share View post →
Dough
@teamlemonslushy.com · Bluesky

VA said I should have witnessed the event. Not learned about it. Contradicting their own DSM-5 guidelines.

Sep 29, 2025 · 1 like View post →
PsychConcierge
@psychconcierge.com · Bluesky

A Study to Evaluate the Maintenance Effect of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

Sep 29, 2025 View post →
Today headline
@todayheadline.bsky.social · Bluesky

Ketamine, depression and childhood trauma: new evidence from a community study Childhood trauma is one of the biggest risk factors for major depressive disorder; in fact, studies have shown that it increases the risk of depression by more than twofold (Li, D’Arcy and Meng 2016, Otte et al 2016).…

Sep 29, 2025 View post →
RJ Sketch! (SFW)
@arrjaysketch.bsky.social · Bluesky

It's true! Many years ago, I'm sure I had an episode of major depressive disorder for years, and I had no idea anything was wrong. I knew all about depression, but it was super hard to self-identify, let alone ask for help. It's tough!

Sep 27, 2025 · 1 like View post →
The Creatively Maladjusted
@tyrotcm.bsky.social · Bluesky

Cyclothymic!

Sep 27, 2025 · 5 likes · 1 share View post →
rickmcguire.bsky.social
@rickmcguire.bsky.social · Bluesky

Best of: ‘Magic mushrooms (psilocybin) are effective for major depressive disorder and often work for more than 5 years after treatment. bit.ly/4pV9ahA

Sep 27, 2025 View post →
Powerboar
@psyboar.bsky.social · Bluesky

I was officially diagnosed as having a "panic disorder" and "major depressive disorder" lol

Sep 27, 2025 · 2 likes View post →
turkeyneck1349.bsky.social
@turkeyneck1349.bsky.social · Bluesky

If'n the drugs I use are not causing my Life to be chaotic or "unmanageable", to quote the 12-Steppers, how then do I have a "drug PROBLEM"?! I use for a purpose; to self-medicate against a Major Depressive Disorder resistant to conventional treatment. Moreover, it WORKS, & I'm not suffering

Sep 27, 2025 · 1 share View post →
Emil Uffelmann
@euffelmann.bsky.social · Bluesky

A big thank you to Wouter Peyrot for his great supervision and teaching me a great deal about stats gen, and to my other co-authors @daniposthu.bsky.social, Alkes Price, as well as to all members of the schizophrenia and major depressive disorder working groups of the psychiatric genomics consortium

Sep 26, 2025 View post →
Monster Momma ➡️ ANE 2026
@monstermomma.bsky.social · Bluesky

What character permanently altered your brain chemistry? Y'all know me well enough by now. Who knew being a thirsty bitch was a cure for major depressive disorder lol

Sep 26, 2025 · 3 likes View post →
JAACAP Journals
@jaacapjournals.bsky.social · Bluesky

A sample of preschoolers enriched for depression was followed into early adolescence and assessed for suicidal thoughts and behaviors (STBs), major depressive disorder (MDD), attention deficit hyperactivity disorder (ADHD), and oppositional defiant disorder (ODD). https://twp.ai/4ipQWB 1/4

Sep 26, 2025 · 1 like · 1 share View post →
Handgun Yoga
@handgunyoga.bsky.social · Bluesky

High consumption of soft drinks was linked to both a greater likelihood of major depressive disorder and more severe symptoms, particularly among women. The effect appears tied to an increase in Eggerthella bacteria, which have been linked to depression in earlier studies

Sep 26, 2025 · 1 like View post →
SCIENMAG
@scienmag.bsky.social · Bluesky

Neural Networks Linked to Antidepressant Success In a groundbreaking study soon to be published in BMC Psychiatry, researchers have unveiled the intricate neural network dynamics underlying response inhibition deficits in Major Depressive Disorder (MDD), shedding light on their potential role as…

Sep 26, 2025 View post →
Science News
@scinews.bsky.social · Bluesky

Soft drink consumption was significantly associated with diagnosis of major depressive disorder, as well as depression severity. jamanetwork.com/journals/jam...

Sep 25, 2025 · 6 likes · 1 share View post →
rickmcguire.bsky.social
@rickmcguire.bsky.social · Bluesky

‘Magic mushrooms (psilocybin) are effective for major depressive disorder and often work for more than 5 years after treatment. bit.ly/4pV9ahA

Sep 25, 2025 · 1 like View post →
digitaldesert.bsky.social
@digitaldesert.bsky.social · Bluesky

Study links soda consumption with depression. “In this cohort study, soft drink consumption was significantly associated with diagnosis of major depressive disorder, as well as depression severity…” jamanetwork.com/journals/jam...

Sep 24, 2025 View post →
rationalpear.bsky.social
@rationalpear.bsky.social · Bluesky

mmm. once you deep dive narcissism/psychopaths it all makes sense. i hate when ppl say T has skills/charisma. he’s sick in head, and part of the disorder is manipulating ppl. it’s as natural as breathing. it’s like lauding the skill of sadness for those with major depressive disorder.

Sep 24, 2025 · 9 likes · 2 shares View post →
Lia Pas
@liapas.bsky.social · Bluesky

Fascinating research on issues with blood flow in the brain in MDD (Major Depressive Disorder). Low blood volume and low blood flow are issues in #MECFS as well.

Sep 24, 2025 · 20 likes · 7 shares View post →
u24usa.bsky.social
@u24usa.bsky.social · Bluesky

Soda-Major Depression Link; FDA Rejects Rexulti for PTSD; Cobenfy Neutropenia Case (MedPage Today) -- Consuming soft drinks may contribute to major depressive disorder (MDD) through gut microbiota alterations, with stronger effects seen among women, a German study suggested. (JAMA Psychiatry)…

Sep 24, 2025 View post →