A bit of vent art. Probably have Major Depressive Disorder. Went through a bout of it again after Covid. I want to come up with some solutions to help me feel better when I'm in it, but when I'm depressed I don't see a point, and when I'm feeling okay, I can't recall how it felt to be depressed.
Major depressive disorder.
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Jun 2024 – Oct 2025Where it's discussed
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Bluesky120 posts
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X / Twitter100 posts
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Facebook3 posts
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AI synopsis
What people are saying
Many discussions center around personal experiences with major depressive disorder, showcasing a plethora of sentiments about its challenges and treatment options. For instance, one contributor expressed relief at finally receiving a diagnosis, while another criticized the oversimplification of depression in popular media. Phrases like 'it hurts every morning' and 'I’m just waiting on when I'll snap out of it' underscore the ongoing struggle. The tone of these discussions, often blending humor with profound frustration, reveals the complexity of living with major depressive disorder and points to a collective desire for greater understanding and support.
Most discussions reflect a shared understanding and acknowledgment of major depressive disorder's complexities and treatments.
Participants show a strong curiosity about the intersections of mental health and recent research, especially regarding new treatment options.
While many posts express personal experiences or references treatments, deeper discussions on methodologies and efficacy are less common.
Contributors perceive the publication and associated discussions as having substantial implications for awareness and treatment in mental health.
Abstract in brief
- Major depressive disorder (MDD) involves a prolonged depressed mood, loss of interest in activities, recurrent thoughts of death, and various physical and cognitive symptoms, leading to a decreased quality of life.
- MDD is complex, resulting from an interplay of genetic, environmental, psychological, and biological factors rather than a single cause.
- Treatment typically includes antidepressant medications, psychotherapy, or both, and in severe cases, additional treatments like electroconvulsive therapy may be used.
Top posts
Most liked on X and Blueskylegitimately i really do wish people would stop mistaking their own major depressive disorder for politics. it would be better for themselves and also the world
For years, I suffered from major depressive disorder, anxiety disorder, panic attack, and post traumatic stress disorder (PTSD), often wanting to end it all. Those of you who suffer from } #mentalillness know how debilitating it is. Thanks to the psychiatrist, therapist, loved
@Denita_fit It’s called Perinatal Depression and it’s a modifier of Major Depressive Disorder…your claim is why they changed the name https://t.co/bRE2uSnwR6
i'm like if spongebob had major depressive disorder https://t.co/o015tPlrZn https://t.co/xF5JShsRhF
All mentions
Understanding Major Depressive Disorder and Its Impacts
This video explains why depression is considered a serious mental illness, highlighting its complex causes—including genetic and environmental factors. We also review treatment options and provide insights based on…
Understanding the Neurobiology of Depression and Its Treatments
This video explains the biological factors influencing depression, including genetic, biochemical, and stress-related elements, along with current treatment options and the role of healthy habits in managing the…
@MoarSahitoPTI
The latest edition of PCORI’s Emerging Health Care Innovation Brief highlights FDA clearance to BrainsWay for their Deep Transcranial Magnetic Stimulation system protocol to reduce major depressive disorder treatment time from 4 weeks to 6 days, among other regulatory updates. https://t.co/NOgvZ8scJo
RT @Chulbulpanda420: We handle Premenstrual syndrome, We handle Premenstrual dysphoric disorder, We handle Postpartum depression, We handle…
RT @tongamrina: For years, I suffered from major depressive disorder, anxiety disorder, panic attack, and post traumatic stress disorder (P…
@MoarSahitoPTI Sertraline is primarily known as a selective serotonin reuptake inhibitor (SSRI) used to treat major depressive disorder, anxiety disorders, obsessive-compulsive disorder (OCD), and post-traumatic stress disorder (PTSD).
I have ADD and Major Depressive Disorder. The depression has been treated for decades. After the ADD was diagnosed at 50 I took my first Adderal and I was PISSED because I realized that THIS was how most people feel most of the time. https://t.co/KbLGrpGh0L
@MoarSahitoPTI Sertraline is an antidepressant — specifically, it’s in the class of SSRIs (selective serotonin‐reuptake inhibitors).  It’s commonly used to treat: •Major depressive disorder (depression)  •Anxiety disorders (such as social anxiety disorder)  •Obsessive-Compulsive
RT @Chulbulpanda420: We handle Premenstrual syndrome, We handle Premenstrual dysphoric disorder, We handle Postpartum depression, We handle…
Cavity so bad it's eaten almost half my tooth but yeah it's my fault and I totally wanted this it's not because I have a major depressive disorder no way https://t.co/weqwiZnK1u
Molecular Reflection of the Mind: Exosomes in Major Depressive Disorder www.sciencedirect.com/science/arti...
We’re delighted that Dame Carol Robinson (Director, @KavliOxford) will be at The Festival of Genomics and Biodata in London, discussing how #proteomics technologies can be applied to identify and validate novel drug targets for major depressive disorder. More info: https://t.co/MELfptNG15
Excuses are almost never justified, I have had major depressive disorder my whole life to the point where there were years I couldn’t take care of myself and I still figured shit out all alone and my biggest problem back then was blaming everyone but myself.
The Impact of Lifestyle Factors on Major Depressive Disorder: Prioritizing Mental Health in Statesboro, Georgia - https://t.co/9m33MjjBRw
We handle Premenstrual syndrome, We handle Premenstrual dysphoric disorder, We handle Postpartum depression, We handle perimenopausal mood changes, We handle Bipolar affective disorders, We also handle Major depressive disorder, So We can handle women mood swings. But still you https://t.co/ZCrsF5fQQi
We handle Premenstrual syndrome, We handle Premenstrual dysphoric disorder, We handle Postpartum depression, We handle perimenopausal mood changes, We handle Bipolar affective disorders, We also handle Major depressive disorder, So We can handle women mood swings. But still you https://t.co/ZCrsF5fQQi
@redjelyfishgirl its not a site, but an “easter egg” i made ^w^ they are my diagnosis .ᐟ F32 — major depressive disorder F50 — anorexia 584 — autism 542 — ocd working to get the last two diagnosed officially, it takes time to get into the tests and result + official paperwork, but i have them :)
https://t.co/1CwSzLzvu5
Cell-Type-Specific Transcriptomic Signatures in Prefrontal Cortex Reveal lncRNA-mediated Gene Silencing and Enhancer Activities Contributing to the Pathophysiology of Major Depressive Disorder #NeuroDegeneration
https://t.co/5tTYLQmMko
Cell-Type-Specific Transcriptomic Signatures in Prefrontal Cortex Reveal lncRNA-mediated Gene Silencing and Enhancer Activities Contributing to the Pathophysiology of Major Depressive Disorder https://www.biorxiv.org/content/10.1101/2025.10.16.682876v1
Cell-Type-Specific Transcriptomic Signatures in Prefrontal Cortex Reveal lncRNA-mediated Gene Silencing and Enhancer Activities Contributing to the Pathophysiology of Major Depressive Disorder https://www.biorxiv.org/content/10.1101/2025.10.16.682876v1
RT @gjurvetson: This is outstanding. 5 years post treatment with psilocybin therapy (for major depressive disorder), 67% were in remissio…
RT @atari404: i'm like if spongebob had major depressive disorder https://t.co/o015tPlrZn
Self-medicatin against major depressive disorder with a wide array of DEPRESSANTS, it's akin to tryna put out a conflagration with a can of gasoline -- at BEST, it's very counter-productive; typically, it turns out plenty worse'n THAT, you dig it? Ameliorating MY Misery demands STIMULATION;
i'm like if spongebob had major depressive disorder https://t.co/o015tPlrZn https://t.co/xF5JShsRhF
RT @jimmyroybloom: https://t.co/kHUMkKIyGQ via @YouTube Biobanking in everyday clinical practice in psychiatry— Translational research…
Clearly I know about Major Depressive Disorder like the back of my head.
Exploring Treatment Options for Major Depressive Disorder - https://t.co/44FBiw7Xen https://t.co/rxy2P5HYzj
https://t.co/u13uCHYJan
Not seeing improvement for your major depressive disorder? You may be eligible for a research study in Santa Ana exploring an investigational treatment option for adults 18 to 64 years old. Call today. (800) NEW-STUDY | https://t.co/u1TsVA4RvJ #depressionstudy #MDD #ClinicalTrial https://t.co/ZCerG5KTSr
I have seasonal depression where I'm depressed during the hotter months instead of the cold ones so now that it's fall I'm 10x more productive and happy than I was all summer...I have major depressive disorder so life kinda sucks all year round for me but it sucks kinda less now
cant believe major depressive disorder is actually majorly depressive and disordering my life
@witheringfrenzy Diagnosed major depressive disorder at 11 and it’s made my life #miserable ! At least with my bipolar 2 I know the emotions won’t last forever dykwim?
major depressive disorder sucks actually
@MoarSahitoPTI ✅ Answer: SSRI for major depressive disorder and anxiety spectrum (OCD, PTSD, panic, social anxiety, PMDD)
P.S. There is no reason to give me reassurance or comfort, because I'm not asking for it. I'm an old pro at handling this major depressive disorder stuff, so I *know* I'll snap out of it and get better. I'm just waiting on *when*
RT @FranceShedtwt: me when i was diagnosed with major depressive disorder instead of funny guy disorder https://t.co/U7lvr47iXh
that major depressive disorder be hitting sometimes https://t.co/wDrpnRwEMz
@blyyyd bro like major depressive disorder and schizophrenia run RAMPANT in my family brah i know i can handle it for the most part but my kid??? i wouldn't ever want to give them that cross to bear
RT @BodyExplained: @MoarSahitoPTI known for treating Major depressive disorder (MDD) Obsessive-compulsive disorder (OCD) Panic disorder…
@Chan_Channnnn @Denita_fit @therealchilotam She defined it as the abrupt drop in estrogen and progesterone. That occurs when a lot of tissue and an entire organ are expelled out of the uterus and vagina. What you described are usual causes of Major Depressive Disorder and it’s very serious and requires therapy.
RT @tongamrina: For years, I suffered from major depressive disorder, anxiety disorder, panic attack, and post traumatic stress disorder (P…
Understanding Major Depressive Disorder: An Overview - https://t.co/A30IaqFnp7
Major Depressive Disorder Some Encouraging Words From Dr. David Samuels - https://t.co/IQwMbWzH79 https://t.co/RS5RRBPL0t
RT @tongamrina: For years, I suffered from major depressive disorder, anxiety disorder, panic attack, and post traumatic stress disorder (P…
@xelalanana i believe in you xela! i've been of my meds for major depressive disorder + anxiety since 2020 (hindi na afford) for my case i was able to manage it , i learned that journalling surprisngly did help and def a good support system
@Smttywerben69 @ronin_blades @synticat0r @Paul40805337 @qurvoebana @RAZ0RFIST @Crzy65 No, depression is primarily a mental illness itself, classified as major depressive disorder in diagnostic manuals like the DSM-5. While it can manifest as a symptom of other conditions such as bipolar disorder or certain physical illnesses, most clinical cases are treated as a
RT @BodyExplained: @MoarSahitoPTI known for treating Major depressive disorder (MDD) Obsessive-compulsive disorder (OCD) Panic disorder…
RT @Ssu6275: #低落 信樂膠囊 Fluoxetine 主治:憂鬱症、強迫症、焦慮症、暴食症等 安靜錠Lorazepam 主治:焦慮、緊張、恐慌、失眠等 快安平Quetiapine 主治:情緒起伏、躁症、妄想、助眠等(低劑量常用於睡眠與焦慮輔助) ① 重度憂鬱症…
That it matched the Creator's own depression but in my opinion he definitely has either persistent or major depressive disorder or its both there's no in between. Also some speculations that he is autistic I don't know. He has autistic traits but I don't think he's actually
Therapy that Shinji did not have AT ALL. If you're asking what specific type of depression the one that I have major depressive disorder and he probably has persistent depressive disorder I wouldn't be shocked. All done by severe trauma and also his severe loneliness
Dissecting Pleiotropy Between Major Depressive Disorder and Physical Disease Comorbidities https://www.medrxiv.org/content/10.1101/2025.10.14.25337939v1
@Denita_fit It’s called Perinatal Depression and it’s a modifier of Major Depressive Disorder…your claim is why they changed the name https://t.co/bRE2uSnwR6
RT @tongamrina: For years, I suffered from major depressive disorder, anxiety disorder, panic attack, and post traumatic stress disorder (P…
RT @tongamrina: For years, I suffered from major depressive disorder, anxiety disorder, panic attack, and post traumatic stress disorder (P…
@MoarSahitoPTI
@olliethetanuki i have a major depressive disorder and am a medieval nerd let me hit u up
What do you MEAN I have major depressive disorder. What
October is #DepressionAwarenessMonth My name is Zak and I suffer from Major Depressive Disorder. It's important for me to talk about to destigmatize the narrative around men's mental health. Men die by suicide rate 4x higher than women. Mostly bc of shame Help is available www.988california.org
@Dyeo85 @PressSec @teampelosi Alcohol Use Disorder- AUD are major depressive disorder and bipolar disorder.
Guess who just got diagnosed with major depressive disorder
I’m literally diagnosed with major depressive disorder but the closest person to me in my life constantly says I should practice gratitude I’m sooooooooo
@shiftillust Get tested. I thought I had adhd (I do the same thing) and it turns out I had a minor case of major depressive disorder.
RT @washingtonpost: I was just 11 when I had my first experience with depression, writes Danielle Hayden. When she became a mother, things…
For years, I suffered from major depressive disorder, anxiety disorder, panic attack, and post traumatic stress disorder (PTSD), often wanting to end it all. Those of you who suffer from } #mentalillness know how debilitating it is. Thanks to the psychiatrist, therapist, loved
This whole thread pisses me off, as someone who did not grow up with “gentle parents” and I have enormous amounts of resentment and anger towards them bc of it. I have GAD and major depressive disorder but I had nearly the opposite experience. https://t.co/9PzDg80JN9
Since the first transcranial magnetic stimulation (TMS) system was cleared by the U.S. Food and Drug Administration in 2008 to treat major depressive disorder in adult patients, the field of TMS has experienced tremendous growth. https://t.co/bpTheABc1h https://t.co/Az7WVkJpeB
@oelma__ Scripture. Daily. I stand it on its spine, and just randomly let it open. You will be surprised how often it is relevant. I have Major Depressive Disorder. CPtsd, and anxiety. I do take Prozac for the chemical imbalance, and my therapy is the Word of God and self forgiveness.
Syrentis Clinical Research is looking for adults 18 to 64 years old in Santa Ana with major depressive disorder. You may be eligible for a research study testing an investigational treatment option. Learn more. (800) NEW-STUDY | https://t.co/u1TsVA4RvJ #depression #ClinicalTrial https://t.co/KPOmQQkTz2
diagnosed major depressive disorder, anxiety, and adhd but i suspect onset bipolar disorder cause it runs in ym family and would just make the most sense https://t.co/9k0htqVmGZ
RT @Ratspitt: In a recent study 95% of people that suffer from (MDD) Major Depressive Disorder responded positively to photos of Sydney Swe…
@MoarSahitoPTI known for treating Major depressive disorder (MDD) Obsessive-compulsive disorder (OCD) Panic disorder (PD) Post-traumatic stress disorder (PTSD) Social anxiety disorder (SAD) Premenstrual dysphoric disorder (PMDD)
Major depressive disorder means the suffering is way beyond your comprehension.
RT @agingdoc1: Epigenetic Clocks Identify Harmful Epigenetic Aging Linked to Depression Severity and Cognitive Deficits in Major Depressive…
New research links soft drink intake to major depressive disorder (MDD) in women — and the gut microbiome may play a key role.
Spravato® — an FDA-approved nasal spray designed specifically for treatment-resistant depression and major depressive disorder (MDD) with suicidal thoughts. Call today to see if you’re a candidate for SPRAVATO. Phone: 817-722-6078 Website: https://t.co/cjFouSdtpR https://t.co/MVgIHSNoQ4
I was my own first patient of "Major depressive disorder".
RT @bluesunkiss_: —All About Borderline Personality Disorder (BPD)
@RobertHerve12 @TudorChick1501 Lucky you! Didn’t work for my sister nor anyone we knew in her support group. Clinical depression is a major disorder also known as major depressive disorder is not easy to cure. There is no quick fix. Meghan went from suicidal to perfectly smiley happy within no time! Impossible
RT @KemtrupTweets: eg Major Depressive Disorder. Reifying these things is pernicious. But all told, we have to be careful not to over corr…
Seltorexant Well-Tolerated in Adolescents as an Adjunct Treatment for Major Depressive Disorder https://t.co/OYxbHJYJ1R https://t.co/oD8F5WwWXx
@SpillTheMemes Major Depressive Disorder and Detachament Trauma.
@littlekitajoi @skylarromines Here’s one that shows that SSRIs may alter amygdala activity and functional connectivity in major depressive disorder: https://t.co/vUM3wE2c31
@daramgaria I write poetry, I like to think I am occasionally funny, and despite barely having a handle on Major Depressive Disorder I endure
Consumption of soft drinks may be linked to a diagnosis of major depressive disorder (MDD), along with more severe symptoms, most notably in women, a study has found. This could be in part due to changes in the gut microbiota.
Oh ya its depression awareness month so u guys have to be aware of me cause i have mdd hahahah hahaha isnt that so funny that i have mdd hahahahahhahah aahahhahaaa hahaha i have major depressive disorder what thats crazy and impossible hahahahhahahah ahahaha hhahahaahaha https://t.co/t92sReleFr
I really want him to get the help he needs for major depressive disorder. https://t.co/PgdJ8tgIMf
@kirasuika25914 @Dearme2_ Go to the gym and eat healthier. I suffer from major depressive disorder and going to the gym and eating healthy changed my life. There is no excuse. Quit crying and make it happen. Life is hard for all of us.
Early heart rate changes after starting intermittent theta burst stimulation (iTBS) for major depressive disorder could help serve as a predictor of treatment response, a quadruple-blind crossover trial indicated. https://www.medpagetoday.com/psychiatry/depression/117931
Early heart rate changes after starting intermittent theta burst stimulation (iTBS) for major depressive disorder could help serve as a predictor of treatment response, a quadruple-blind crossover trial indicated. https://t.co/vptJ371R8s
@Dearme2_ If 20-40mg of daily Cialis was approved for Major Depressive Disorder it would command 100% of the male market and eliminate it entirely. NOBODY can change my mind about this.
Mind Medicine (MindMed) ($MNMD) closed at $12.61 today, up 2.94% from its last close. The company, which develops novel product candidates for brain health disorders like Generalized Anxiety Disorder and Major Depressive Disorder, has been the subject of recent discussion.
RT @washingtonpost: I was just 11 when I had my first experience with depression, writes Danielle Hayden. When she became a mother, things…
RT @washingtonpost: I was just 11 when I had my first experience with depression, writes Danielle Hayden. When she became a mother, things…
@ibuildthecloud I have treatment-resistant major depressive disorder. I am on a new experimental medication, though, that is showing some promise. I’m also a fairly public figure in my niche part of the tech industry. It’s hard to always compartmentalize. We are whole people and should be.
RT @ParveenYograj: #PsychTwitter #MentalHealthTwitter @NIMHANS_BLR @APApsychiatric @APAHealthyMinds @srinivasaiims @PsychiatryAdv @IndianPs…
I'm at the major depressive disorder, I'm at the transsexualism, I'm at the combination major depressive disorder transsexualism
A research study for major depressive disorder in Santa Ana is seeking adult volunteers 18 to 64 years old. Learn more. (800) NEW-STUDY | https://t.co/u1TsVA4RvJ #depression #depressiontreatment #depressionstudy #ClinicalTrials #MentalHealthMatters https://t.co/6ltBKXBy3x
once i claw my way out this depressive episode i need to get back on it with soup-making. i’m so good at making soups and i reckon that it’s genetic (like the major depressive disorder). pics for reference
@Dearme2_ Please stop saying such stupid things. Severely depressed people even think of committing suicide. And for gods sake do not compare a normal person to a person with major depressive disorder. Being sad is not depression.
Also if you click through to the administrative ruling you’ll see they justified pulling the guys clearance on a diagnosis of major depressive disorder pretty cool that everybody in the nuclear weapons complex is aware that if they seek mental health treatment, their career could be in jeopardy.
if you saw this three times shut the fuck up i kept remembering the disadvantages… forgot to put probably bpd or major depressive disorder but beggers cant be choosers
Epigenetic Clocks Identify Harmful Epigenetic Aging Linked to Depression Severity and Cognitive Deficits in Major Depressive Disorder https://t.co/vLIAIdEljO
I have suffered from Major Depressive Disorder all of my life. I got diagnosed in my 20s. I finally got the answer to what I have been feeling. This is accurate. It hurts every morning, every hour, and every minute to be alive. https://t.co/idAAIR6a8Y
RT @DuplexDoesArt: My doctor says my Reccurent Major Depressive Disorder is in partial remission
My doctor says my Reccurent Major Depressive Disorder is in partial remission
RT @NewSamawal: A permanent ceasefire took hold, and the ceasefire-now crowd fell into major depressive disorder.
RT @washingtonpost: I was just 11 when I had my first experience with depression, writes Danielle Hayden. When she became a mother, things…
@Rach4Patriarchy In Canada it's soo bad, it's called M.A.I.D. (Medically assistance in dying), the current liberal government is obsessed with it, even proposing it for those with actual mental illness (including kids) like major depressive disorder, instead of getting them help. It's pure evil.
A permanent ceasefire took hold, and the ceasefire-now crowd fell into major depressive disorder.
Please join us Tuesday October 28 at the CNCR seminar hosted by Dorret Boomsma and Danielle Posthuma: "
the major depressive disorder cognitive biotype+ represents ~27% of depressed patients. just the intro at this link gives some background on it. i'll give a bit more info in the thread: clinicaltrials.gov/study/NCT041...
I was just 11 when I had my first experience with depression, writes Danielle Hayden. When she became a mother, things only got more complicated. Here's how to navigate parenthood and major depressive disorder, according to experts:
In their latest work, Oppenheimer and colleagues found that shared cardiovascular factors genetically link pregnancy-related disorders with major depressive disorder and Alzheimer's disease, highlighting BMI as a crucial modifiable factor for prevention.
For those wondering, here are the official diagnoses I was given: ➣ Anxiety disorder ➣ Attention-deficit hyperactivity disorder (ADHD) ➣ Major depressive disorder, recurrent episodes with mood-congruent psychotic features (Last bit below)
Lower insulin resistance in Chinese patients with severe major depressive disorder: associations with the inflammatory response https://www.medrxiv.org/content/10.1101/2025.10.10.25337709v1
how i’d probably sleep if i didn’t have crippling anxiety and major depressive disorder, or responsibilities
Hippocampal Changes Linked to Somatic Depression In a groundbreaking study published in BMC Psychiatry, researchers have unveiled critical neurobiological distinctions underlying somatic depression, a distinct subtype of major depressive disorder (MDD). This research delves into the hippocampal…
recent clinical trial by Leanne Williams and colleagues investigated guanfacine, an α2A adrenoreceptor agonist traditionally used for high blood pressure, as a targeted treatment for a neurobiologically defined cognitive biotype of major depressive disorder. www.nature.com/articles/s44...
So a symptom of Major Depressive Disorder that might seem counterintuitive is anger issues. While I usually have this under control through cbt strategies & meds (no meds atm under Dr supervision), I do still have the occasional breakthrough where even a little snippy barb leaves me fuming for hours
As a species. If you are depressed? GOOD. IT MEANS YOU ARE AWAKE! Depression is the gateway to truth. Truly, I empathize with all of you as someone who has major depressive disorder on her scripts as well, but you need to understand this about your depression. ~ youtu.be/UFnjf58-OmQ?...
realizing that I don’t hate the fall I hated major depressive disorder
E5 is such a funny ennea to me. Sorry thats just an incel. Like. Literally. They're either incels or have major depressive disorder
That user edit history though. It’s so good. I can’t decide which one is my favorite. There’s: The two edits to update the latest showing of Drake & Josh The spelling correction of “Meenwhille” to “Meanwhille” Just fucking up the heading of Major depressive disorder for no reason
legitimately i really do wish people would stop mistaking their own major depressive disorder for politics. it would be better for themselves and also the world
I died laughing at this cause I literally have diagnosed major depressive disorder with PSYCHOTIC features. Baby me didn’t know at the time lmao
Well, without my store bought brain chem meds, I’ll just be over here planning my escape to the underworld. Which I’m sure is the point, since major depressive disorder makes me useless to the fascists.
As someone with Major Depressive Disorder, General Anxiety Disorder, C-PTSD, & ADHD (possible other dx’s,too) … my #mentalhealth is always something I’m aware of. #Therapy has been a big part of my life for the past 5years Mental Health matters; everyone should have access to resources & treatment
EEG-based brain connectivity and sentiment analysis from smartphone social communication: insights into remitted major depressive disorder among adolescents www.nature.com/articles/s44...
it's #WorldMentalHealthDay I battle bi-polar II, CPTSD, major depressive disorder, and general anxiety. our battles are exhausting and frankly misunderstood. if you want to help, research, hold our hands, and listen to us, even when we're silent.
Johnson & Johnson Showcases Innovative Treatments for Major Depressive Disorder at ECNP 2025 #USA #Johnson_&_Johnson #Major_Depressive_Disorder #treatment-resistant_depression #Titusville,_NJ
The level of absolute sass from Norwegian spoonies on here around world mental health day is truly legendary. Like. I aspire to this. Next time my health centre sends me spam asking if I've considered going outside to help my severe major depressive disorder? (Cracks knuckles) I'll be ready.
Open Access UCL Research: Exploring the dynamic relationships between nocturnal heart rate, sleep disruptions, anxiety levels, and depression severity over time in recurrent major depressive disorder discovery.ucl.ac.uk/id/eprint/10...
i'm the very model of a modern major depressive disorder i've anxiety general and personality-line border
my major depressive disorder just got promoted to brigadier depressive disorder. the brigade is already here, tormenting me ☺️
Medicaid Expansion and Inpatient Hospital Charges Among Women with Major Depressive Disorder https://www.medrxiv.org/content/10.1101/2025.10.07.25337532v1
The acute phase inflammatory response as a key determinant of reduced lipid-associated antioxidant defenses in Chinese patients with major depressive disorder https://www.medrxiv.org/content/10.1101/2025.10.08.25337557v1
Alterations in serum nudifloramide associated with response to diverse pharmacological treatments in major depressive disorder: a preliminary study #MetabBrainDis #MassSpec link.springer.com/article/10.1...
Soft Drink Consumption Linked to Major Depressive Disorder Consumption was linked to increased Eggerthella abundance, which mediated the soft drink-MDD association www.healthday.com/healthpro-ne...
The risk of #dementia is greater among elderly patients with major depressive disorder who are resistant to antidepressant medication. Published in @psychiatryadvisor.bsky.social. https://bit.ly/4mRk5G8
Post-ECT Maintenance Drugs in Major Depression In the evolving landscape of psychiatric treatment for major depressive disorder (MDD), the quest for optimizing maintenance strategies following electroconvulsive therapy (ECT) has reached a pivotal moment. A groundbreaking study recently published…
As a person who suffers from major depressive disorder and anxiety, I feel this
Nou article a #Docusalut: Longitudinal associations between melancholic depression and executive function in adult patients with major depressive disorder: a 12-month follow-up study http://hdl.handle.net/20.500.13003/25437 @idisba.bsky.social #PublicaSalutIB
Efficacy and safety of remote ischemic conditioning for depression ins https://www.newsbeep.com/ca/196612/ Introduction Major depressive disorder (MDD), characterized by its high incidence rates, relapsing nature, and increased suicide risk, puts…
Cellular and Soluble Immune Signs in Major Depression In a groundbreaking advancement toward unraveling the biological underpinnings of major depressive disorder (MDD) and suicidal behavior, researchers have embarked on an integrative exploration of immune system signatures that differentiate…
love it when I read an article that says ADHD, schizophrenia, major depressive disorder, and OCD (among a few others) are psychiatric disorders that tend to cluster in families, because have you been to my house?
yuno - aroace. i am so passionate about this. aroace yuno. i think about this on a daily basis esp in the context of 0207 narrative foils. such a concept - probably has dpdr + the lovely thing called. major depressive disorder. i am not projecting here - super uncanny gaydar (canon)
Shared Brain and Molecular Links in Diabetes, Depression In a pioneering study published in Translational Psychiatry, researchers have illuminated striking overlaps in the neurobiological and molecular landscapes of type 2 diabetes mellitus (T2DM) and major depressive disorder (MDD). This…
Sex-stratified genome-wide association meta-analysis major depressive disorder Discussion
Reelin: A Promising Protein for Gut Repair and Depression Treatment In a groundbreaking study emerging from the University of Victoria, researchers have identified a promising new frontier in the treatment of major depressive disorder (MDD) by targeting what might be considered an unlikely player…
• 15q11.2 deletion syndrome • XYY syndrome • Triple X syndrome (XXX) Psychiatric Conditions: • Autism spectrum disorders • Attention deficit hyperactivity disorder (ADHD) • Major depressive disorder
“These findings underscore the importance of considering sex-specific genetic architectures in the study of health conditions, including Major Depressive Disorder, paving the way for more targeted treatment strategies.” www.nature.com/articles/s41...
Open access link to new study in Nature Communications: Sex-stratified genome-wide association meta-analysis of major depressive disorder.
Congrats to Tinatin Gamkrelidze, Georgia, on winning the 2025 ECNP Excellence Award.
i used to have major depressive disorder so maybe it’s just breakthrough symptoms and i need to adjust my medication
Primary care doc is updating my formal diagnoses: major depressive disorder, anxiety, US citizen
gonna be real the SSA is fucking ridiculous. tell me how someone like me with ME/CFS, PTSD, BPD, and major depressive disorder gets my social security application rejected
feel like ive been hit by a bus and that bus is major depressive disorder
still pissed at the psychiatrist cause idk i think my behavior isnt just from adhd or spcd or major depressive disorder or generalized anxiety disorder!!!! i literally have family history of bpd and bipolar!!! cause i swear something else is making my behavior strange WAH
alas. Major Depressive Disorder
kind of surprised the happiness is so high considering i have a lovely thing called major depressive disorder
Whenever someone posts a negative typical "remember life is shit and you die" post. I'd like to also give a blunt reminder as someone with major depressive disorder. (Clears throat, takes a breath) YOU ARE NOT HELPING!!!!!!
Okay but fr I need a guy with a huge dick to slap it against my cage while he strokes my face and tells me he's proud of me Wellbutrin is an atypical antidepressant that is indicated in the treatment of major depressive disorder and seasonal affective disorder and to support smoking cessation. It i
A bit of vent art. Probably have Major Depressive Disorder. Went through a bout of it again after Covid. I want to come up with some solutions to help me feel better when I'm in it, but when I'm depressed I don't see a point, and when I'm feeling okay, I can't recall how it felt to be depressed.
When you have treatment-resistant major depressive disorder with comorbid avoidant personality disorder.
I’ll be ok. I’m diagnosed with major depressive disorder and chronic anxiety, so it’s something I’m sorts used to, but when things get extra hard, it hits even harder. I just lost my access to therapy, insurance, medical help, and my job because of something major happening in my personal life
Combs' Agnifilo: He found in the microfilm there how his father died, in a drug deal gone bad. Maybe that's the trauma. He had major depressive disorder. OK. I'm going to sit down in five minutes, then Ms. Slavik, and Mr. Combs, the last word
Online now: A sequential dual-site repetitive transcranial magnetic stimulation for major depressive disorder: A randomized clinical trial
Soft Drinks’ Effect on the Gut Tied to Major Depression Risk https://www.newsbeep.com/nz/58556/ Soft drink consumption is linked to a higher risk for major depressive disorder (MDD) and more severe symptoms…
So I dunno iit was mentioned, but I was diagnosed with major depressive disorder a few months back. Lost friends, my job, struggled to find any good reason to exist or keep trying. Its hard to explain the pit it puts you in mentally. I do not wish it on anyone. Im lucky to be slowly recovering.<3
Thalamo-Cortical Connectivity Shifts in Depression In a groundbreaking new study published in BMC Psychiatry, researchers have illuminated previously uncharted territory in the complex neural interactions underlying major depressive disorder (MDD). The study focuses intently on the…
Depression Alters Theta, Alpha in Memory Tasks In a groundbreaking study that intricately links neurophysiological oscillations with cognitive impairments in mental health, researchers have illuminated how major depressive disorder (MDD) disrupts the brain's working memory updating system. As…
this is not indicated to treat attention deficiency; it's an antidepressant, so why does this feel like i'm speedballing and i'm not even treated for my adhd. what do bipolar individuals w major depressive disorder taking antidepressants do if theyre attention deficit and need intervention???
Yes!!! My mom also swears by this. (And the lamps) I can ask her for tips of all the things she does, specifically in winter, for her major depressive disorder.
“Polygenic genome editing in human embryos and germ cells is predicted to become feasible… editing a relatively small number of genomic variants could make a substantial difference to an individual’s risk of developing coronary artery disease, Alzheimer’s disease, major depressive disorder,”
Diagnostic Model and Subtype Analysis of Depression In a groundbreaking study published in BMC Psychiatry, researchers have unveiled a sophisticated diagnostic model for major depressive disorder (MDD) centered on the intricate role of PANoptosis-related genes. This novel work elevates our…
Take all the time that you need and be safe. Last week I had an appointment with my VA mental health. I was diagnosed with MDD (Major Depressive Disorder) on top with my GAD (Generalized Anxiety Disorder). If you need anypony to talk with I’ll be there to listen.
No one told me that Chicago trains have a Shinji depression ad
Soft drink consumption is linked to a higher risk for major depressive disorder (MDD) and more severe symptoms in women, potentially due to alterations in the gut microbiome, new research showed. ms.spr.ly/63321svStL
Rasch Analysis of Chinese Hamilton Depression Scale In a groundbreaking study set to redefine the assessment of major depressive disorder (MDD) in clinical psychology, researchers have employed Rasch analysis to critically evaluate the self-reported Hamilton Depression Rating Scale (HDRS)…
Realizing there might be a correlation between big Evangelion fans and depression, idk
Soft Drink Consumption Linked to Depression Diagnosis in Women, Study Says https://www.europesays.com/uk/465266/ Consumption of soft drinks may be linked to a diagnosis of major depressive disorder (MDD), along with more…#uk #news #uknews
FREEBIE #1 Has major depressive disorder, focal epilepsy, and possible outsider syndrome.
Soft Drink Consumption Linked to Depression Diagnosis in Women, Study Says https://www.newsbeep.com/us/193256/ Consumption of soft drinks may be linked to a diagnosis of major depressive disorder (MDD), along with more…
Soft Drink Consumption Linked to Depression Diagnosis in Women, Study Says https://www.newsbeep.com/nz/52799/ Consumption of soft drinks may be linked to a diagnosis of major depressive disorder (MDD), along with more…
Soft Drink Consumption Linked to Depression Diagnosis in Women, Study Says https://www.newsbeep.com/uk/171255/ Consumption of soft drinks may be linked to a diagnosis of major depressive disorder (MDD), along with more…
Narcissistic Personality Disorder is a mental illness. Obviously very different from more common general anxiety disorder or major depressive disorder, but a mental health condition nonetheless. I think that’s more what Conway means.
Soft Drink Consumption Linked to Depression Diagnosis in Women, Study Says https://www.newsbeep.com/il/47478/ Consumption of soft drinks may be linked to a diagnosis of major depressive disorder (MDD), along with more…
if you recognise this car you may meet diagnostic criteria for major depressive disorder
Treatment-resistant depression (TRD) represents a significant clinical challenge, affecting approximately 30% of individuals with major depressive disorder (MDD) who fail to respond to at least two adequate antidepressant trials. Read Neurotorium's article via: neurotorium.org/article/trea...
Yuyang Sha, Hongxin Pan, Gang Luo, Caijuan Shi, Jing Wang, Kefeng Li: MDD-Thinker: Towards Large Reasoning Models for Major Depressive Disorder Diagnosis https://arxiv.org/abs/2509.24217 https://arxiv.org/pdf/2509.24217 https://arxiv.org/html/2509.24217
People focus on the alcohol, but we know much more. Research consistently shows that people with alcohol use disorder (AUD) are far more likely to also experience major depressive disorder, or otherwise stated as mood disorders, failing to get mental health treatment- no one comes out unscathed.
Been extra moody and antisocial lately. Perimenopause: “Don’t look at me. I’m just here for brain fog and irregular cycles.” Major depressive disorder: “You blame me for literally everything. I can’t ever do right in your eyes.” *blood test results return* Hypothyroidism: “I’M BACK, BITCHES!” Me:
That's what I thought before I was diagnosed to bipolar instead of major depressive disorder. Spent many years dealing with med roulette to find the ones that work. Then, something in me snapped. I had just stepped out of a 30yr bout of depression. Was the sky always this blue?- #bipolarsky
I love that! And it’s pretty similar to mine—I looked at how our social behaviors and mental health conditions impact physical health moving forward. Specifically, how connectedness can interrupt the pathway between major depressive disorder and type 2 diabetes.
If you have major depressive disorder you really should just quit all the online fighting. It isn't good for your health
NPAS2 gene variants modulate the #circadian preference- #depression link in Major Depressive Disorder: A mediation role of #sleep and somatic symptoms www.tandfonline.com/doi/full/10....
VA said I should have witnessed the event. Not learned about it. Contradicting their own DSM-5 guidelines.
A Study to Evaluate the Maintenance Effect of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Ketamine, depression and childhood trauma: new evidence from a community study Childhood trauma is one of the biggest risk factors for major depressive disorder; in fact, studies have shown that it increases the risk of depression by more than twofold (Li, D’Arcy and Meng 2016, Otte et al 2016).…
It's true! Many years ago, I'm sure I had an episode of major depressive disorder for years, and I had no idea anything was wrong. I knew all about depression, but it was super hard to self-identify, let alone ask for help. It's tough!
Cyclothymic!
Best of: ‘Magic mushrooms (psilocybin) are effective for major depressive disorder and often work for more than 5 years after treatment. bit.ly/4pV9ahA
I was officially diagnosed as having a "panic disorder" and "major depressive disorder" lol
If'n the drugs I use are not causing my Life to be chaotic or "unmanageable", to quote the 12-Steppers, how then do I have a "drug PROBLEM"?! I use for a purpose; to self-medicate against a Major Depressive Disorder resistant to conventional treatment. Moreover, it WORKS, & I'm not suffering
A big thank you to Wouter Peyrot for his great supervision and teaching me a great deal about stats gen, and to my other co-authors @daniposthu.bsky.social, Alkes Price, as well as to all members of the schizophrenia and major depressive disorder working groups of the psychiatric genomics consortium
What character permanently altered your brain chemistry? Y'all know me well enough by now. Who knew being a thirsty bitch was a cure for major depressive disorder lol
A sample of preschoolers enriched for depression was followed into early adolescence and assessed for suicidal thoughts and behaviors (STBs), major depressive disorder (MDD), attention deficit hyperactivity disorder (ADHD), and oppositional defiant disorder (ODD). https://twp.ai/4ipQWB 1/4
High consumption of soft drinks was linked to both a greater likelihood of major depressive disorder and more severe symptoms, particularly among women. The effect appears tied to an increase in Eggerthella bacteria, which have been linked to depression in earlier studies
Neural Networks Linked to Antidepressant Success In a groundbreaking study soon to be published in BMC Psychiatry, researchers have unveiled the intricate neural network dynamics underlying response inhibition deficits in Major Depressive Disorder (MDD), shedding light on their potential role as…
Soft drink consumption was significantly associated with diagnosis of major depressive disorder, as well as depression severity. jamanetwork.com/journals/jam...
‘Magic mushrooms (psilocybin) are effective for major depressive disorder and often work for more than 5 years after treatment. bit.ly/4pV9ahA
Study links soda consumption with depression. “In this cohort study, soft drink consumption was significantly associated with diagnosis of major depressive disorder, as well as depression severity…” jamanetwork.com/journals/jam...
mmm. once you deep dive narcissism/psychopaths it all makes sense. i hate when ppl say T has skills/charisma. he’s sick in head, and part of the disorder is manipulating ppl. it’s as natural as breathing. it’s like lauding the skill of sadness for those with major depressive disorder.
Fascinating research on issues with blood flow in the brain in MDD (Major Depressive Disorder). Low blood volume and low blood flow are issues in #MECFS as well.
Soda-Major Depression Link; FDA Rejects Rexulti for PTSD; Cobenfy Neutropenia Case (MedPage Today) -- Consuming soft drinks may contribute to major depressive disorder (MDD) through gut microbiota alterations, with stronger effects seen among women, a German study suggested. (JAMA Psychiatry)…