The collection centers on a meta-discussion of the SELECT trial (Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes). Most posts highlight the 20% reduction in major cardiovascular events in non-diabetic overweight/obese individuals with preexisting cardiovascular disease, underscore the trial’s size and duration, and discuss broader implications for obesity treatment, access, and health policy. Tone ranges from enthusiastic endorsement of cardiovascular benefits to cautious notes about conflicts of interest, cost, and applicability to different BMI ranges or normal-weight patients. Word choices such as “significant reduction,” “heart protection,” and “world-changing” convey optimism, while caveats about adverse events and study design reflect critical engagement.
AgreementModerate agreement
Overall tone is supportive of the study's findings, with some skepticism about conflicts of interest and applicability, leading to moderate agreement.
InterestHigh interest
Very high interest across posts, many referencing data, trials, and implications for practice.
EngagementModerate engagement
Engaged discussions with references, questions, and critiques, though some posts are merely sharing links or praising the trial.
ImpactModerate impact
Notable potential impact discussed (policy, access, cost, reclassification), but some skepticism about generalizability and real-world uptake.
Abstract in brief
Semaglutide, a drug known to reduce heart problems in diabetic patients, was tested to see if it can also lower cardiovascular risks in overweight or obese people without diabetes who already have heart disease.
In a large study with over 17,600 participants, those taking semaglutide had fewer major heart-related events, like heart attacks, strokes, or death from heart causes, compared to those taking a placebo.
The treatment was generally safe, although some participants stopped the medication due to side effects, but overall, semaglutide proved to be more effective than placebo in preventing serious cardiovascular outcomes in this high-risk group.]
Nov 11, 2023 · 165 likes · 54 shares · 9,167 followersView post →
JW
Josh Walkos
@JoshWalkos · X
Only 12 of the 15 Study Authors have direct affiliation with the drugs manufacturer Novo Nordisk. However don’t worry they have all declared that despite their conflicts of interest they in fact have none to declare. ??♂️
So ask your doctor if Novo Nordisk’s GLP-1 receptor
@mikex163 @StatisticUrban Guess you didn't read the paper, "Semaglutide and Cardiovascular Outcomes **in Obesity** without Diabetes."
The semaglutide group lost 10% of their body weight, on average. https://t.co/RowvS3ufXn
May 28, 2024 · 128 likes · 1 share · 12,942 followersView post →
JW
Josh Walkos
@JoshWalkos · X
Steven Kahn
•Position: Advisory roles in several pharmaceutical companies
•Interests:
•Advisory board member for AltPep, Anji Pharmaceuticals, Boehringer Ingelheim, Eli Lilly, Intarcia, Merck, Novo Nordisk
•Manuscript Title: “Semaglutide and Cardiovascular Outcomes in
Explores weight loss from semaglutide in obesity over 68 weeks and how most of the gains fade during a 1-year withdrawal, with diminishing cardiometabolic benefits. Highlights the need for ongoing care to sustain health…
Semaglutide reduces cardiovascular risks in obese individuals without diabetes, lowering instances of heart attacks, strokes, and death from heart causes. The study involved over 17,600 participants and demonstrated the…
Semaglutide, a drug known to reduce heart problems in diabetic patients, was tested to see if it can also lower cardiovascular risks in overweight or obese people without diabetes who already have heart disease.
This video reviews the 2024 nephrology and hypertension study highlights, focusing on semaglutide's benefits. The study shows semaglutide significantly reduces major cardiovascular events in overweight or obese…
This video provides a clear, study-based explanation of whether Ozempic, Wegovy, and Mounjaro weight loss pens cause rebound effects, why they happen, and how to avoid regaining lost weight. Designed for safe…
This week, Dr. John Mandrola discusses the PREVENT score, GLP1 mechanism in cardiovascular disease, statin benefits, and issues with hospitalization endpoints in heart failure trials. Key insights include comparing…
This week in cardiology discusses the VENTOUX study on endurance athletes and arrhythmias, the ongoing debate between rate and rhythm control in atrial fibrillation, and the role of GLP1 drugs. The importance of…
This podcast covers vulnerable plaque, industry payments to trainees, and the trial design of tirzepatide versus dulaglutide. Insights on major adverse cardiovascular events in type 2 diabetes patients are discussed…
This week, John Mandrola MD discusses screening for valvular heart disease, the efficacy of multivitamins, and the role of CPAP in preventing cardiovascular events in sleep apnea patients. The insights highlight recent…
The video discusses the latest findings in cardiology, including an Impella update, the TAVI vs SAVR trial, and studies on angina and PCI. Focused on percutaneous coronary intervention, it examines its impact on…
Explains how semaglutide alters appetite and weight loss, why it lasts a week in blood, common side effects, and what happens after stopping treatment.
This video explores the role of GLP-1 receptor agonists in addressing obesity and other health issues. It reviews recent innovations, their effectiveness in treating obesity, heart disease, and neurodegenerative…
This video discusses a study showing semaglutide lowers cardiovascular risks in overweight or obese individuals without diabetes, with fewer heart-related events observed in over 17,600 participants, highlighting its…
Semaglutide reduces major cardiovascular events in overweight or obese patients without diabetes, showing promise for enhancing heart health in high-risk populations.
Join our scientific team as we discuss the three most impactful clinical papers of November 2023. This month’s highlights include a study on dapagliflozin in myocardial infarction without diabetes, showcasing its…
This week’s podcast reviews significant trials including NOAH-AFNET 6 and ARTESiA that highlight the role of direct oral anticoagulants (DOACs) in preventing ischemic stroke among patients with device-detected atrial…
GLP1 medications, identified in the 1980s and FDA-approved since 2005, play a crucial role in blood sugar control by increasing insulin production. Clinical trials show significant weight loss averaging 15%, with…
Semaglutide: about 65 in 1,000 had a heart attack, stroke or died from heart disease, versus 80 on placebo over ~3 years. Adults had heart or blood vessel disease and excess weight, no diabetes. More stopped for side effects. SELECT (2023): https://t.co/VPzOK8x5f2 https://t.co/TzUpYAvOIt
@RomeoNovem66215 @mxyplyk @newstart_2024 @fluffyguy @ClubShayShay Well your best friend is a retard. Ozempic “dissolves” hearts and diaphragms is the dumbest thing I've heard. Semaglutide has actually reduced cardiovascular events in several large clinical trials. Feel free to post your study or kindly stfu.
https://t.co/sQS4Ol7cx5
Si está buscando un método para bajar de peso y en redes le dicen que lo puede conseguir solo con alimentación y/o otras personas solo con medicamentos, tal vez le están contando la mitad de la historia.
Lea este artículo para entender mejor. https://t.co/A7A8QICpLQ
Oct 21, 2026 · 6 likes · 12,739 followersView post →
EB
Enhanced Guides | Research & Biohacking
@enhancedguides · X
https://t.co/33sU2XujtL
Oct 19, 2026 · 1 like · 10 shares · 2,511 followersView post →
17,604 people with heart disease and a BMI over 27 (overweight), no diabetes, took semaglutide or a placebo for 3 years.
Heart attack, stroke or cardiovascular death: 6.5% against 8.0%.
Side effects stopped the drug in 17%, against 8% on placebo.
https://t.co/mZrOQSHocH
SELECT: 6.5% vs 8.0% had a cardiovascular event. Participants already had cardiovascular disease; this is not proof of universal lifespan extension.
New England Journal of Medicine (2023)
pubmed.ncbi.nlm.nih.gov/37952131/
AI-assisted. Educational, not medical advice.
12/ Selected references — Thread 3: Obesity: Prevention AND Treatment
Not comprehensive, but these are several of the principal sources underlying the thread:
• WHO. Obesity and overweight. Updated 2025.
Overview of obesity as a chronic, relapsing, multifactorial disease and
The numbers, straight:
Appetite: about 24% less food a day.
STEP 1, no diabetes: weight down 14.9% at 68 weeks, vs 2.4% on placebo.
SELECT, heart disease, no diabetes: major heart events down 20%.
Source: https://t.co/gx7FLpageh
Source: https://t.co/vNYWS0kjXE
@XainzaP The CV data made this concrete: SELECT (17,604 adults, overweight/obesity + CVD, no diabetes) cut major cardiovascular events 20% with semaglutide — treating obesity itself moved hard outcomes, and trial design followed. https://t.co/rZHgqy81I9
The papers, so you do not have to take our word for it:
Diabetes Obes Metab 2017: 10.1111/dom.12932
N Engl J Med 2021: 10.1056/NEJMoa2032183
N Engl J Med 2016: 10.1056/NEJMoa1607141
N Engl J Med 2023: 10.1056/NEJMoa2307563
Can we talk about the heart data for a second?
In SELECT, semaglutide reduced major cardiovascular events in adults with heart disease and overweight/obesity, without diabetes. That's a hell of a finding.
https://t.co/yGfN9N8OTq https://t.co/dcirl8o3yR
@Josh_fitcheck13 Context: SELECT showed semaglutide cut MACE by 20% in people without diabetes, so the bar is set. Tirzepatide's dedicated CV-outcomes trial is still pending — different evidence stages, not a fair race yet. https://t.co/rZHgqy81I9
Aquí te dejo los links:
Lincoff AM, Brown-Frandsen K, Colhoun HM, et al. Semaglutide and cardiovascular outcomes in obesity without diabetes. N Engl J Med. 2023;389(24):2221-2232. doi:10.1056/NEJMoa2307563. https://t.co/FFML8Z3PaX
Wong CK, Drucker DJ. Antiinflammatory actions
心血管疾患の既往がある場合、糖尿病がなくても肥満による脳卒中の予防に GLP-1 受容体作動薬を考慮してもよい。
(脳卒中ガイドライン
推奨度 C エビデンスレベル低)。
Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes
PMID 37952131 https://t.co/MEbqzD3JDq https://t.co/xQegdvjCky
Aug 28, 2026 · 9 likes · 2 shares · 7,039 followersView post →
@SamaHoole One question settles the whole exchange: name the randomized trial, any endpoint, any duration, any size, of the protocol the coaching sells.
While that search runs, the other side of the ledger is here.
SELECT https://t.co/X3etcX85rf, SEMALCO https://t.co/crBH3XuEYR, and the
Aug 13, 2026 · 5 likes · 1,034 followersView post →
AD
Ashy Dior
@ashydior · X
@Lee_tilson123 @ZlyukaKoshka @ElizabethRBess @daveryder @krassenstein + link for studies for some light reading https://t.co/h9nvZ7t5pm
https://t.co/c0VIjw2DlI
@Msk20Kushe Yes, we’ve seen the reduction in SELECT (Semaglutide and Cardiovascular Outcomes in Obesity
without Diabetes), and we’re currently waiting on SURMOUNT-MMO, a similar tirzepatide trial looking at cardiovascular outcomes (among others) in patients with obesity and without T2D. https://t.co/5oxAlVbVLI
Special update: progress extending healthy years after 65 is real (GLP-1, SGLT2, BP, strength). Max human lifespan extension? Still unproven.
#HealthOptimization #Longevity #PreventiveHealth https://t.co/3jSzBms3VW
Science News: Could your wellness routine secretly protect your heart and extend your life?
Recent clinical findings show that GLP-1 agonists offer significant protection for your cardiovascular system, reducing major risks by 20%. This benefit works independently of weight https://t.co/DoGS1fADzc
Science News: Könnte eine einfache Spritze dein Herz schützen und das Altern verlangsamen?
Eine große klinische Studie mit über 17.000 Teilnehmern belegt, dass GLP-1-Präparate das Risiko für schwere Herzereignisse wie Herzinfarkte um 20 % senken können. Erstaunlicherweise bietet https://t.co/c3hHz2xSQL
? References & Further Reading
The thread above is a thought experiment about the potential public-health implications of broadly accessible GLP-1 therapies. The underlying evidence comes from a rapidly expanding body of clinical research:
• Wilding JPH et al. (2021).
Jun 1, 2026 · 2 likes · 1,062 followersView post →
CP
Cristina Popa
@CristinaDeReins · X
6/ GLP-1RA and dual GIP/GLP-1 agonists ⬇️ HF risk in high-rosk CKD
?SELECT (obesity + CVD, eGFR 80): semaglutide ⬇️ HF events regardless of eGFR
https://t.co/ui3wAiXwqi
?FLOW (T2D+CKD, eGFR 45), semaglutide ⬇️ reduced 1st HF events by 27% with modest weight loss
May 24, 2026 · 8 likes · 1 share · 460 followersView post →
AT
Abraham Trueba
@CRISPRKING · X
https://t.co/mqqLXEeay6
May 18, 2026 · 2 likes · 10,723 followersView post →
AI
ARK Invest
@ARKInvest · X
https://t.co/ESlTEDIvHJ
May 12, 2026 · 33 likes · 7 shares · 822,312 followersView post →
AT
Abraham Trueba
@CRISPRKING · X
https://t.co/2DHZCHwxKL
May 10, 2026 · 3 likes · 1 share · 10,723 followersView post →
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PeptidePub
@PeptidePub · X
SELECT changed the semaglutide conversation from weight loss to cardiovascular risk.
17,604 adults. Overweight or obesity. No diabetes. Lower major cardiovascular events with semaglutide 2.4 mg.
PubMed: https://t.co/gJ5VNp7AuC
Is heart protection now the real GLP-1 headline?
May 10, 2026 · 1 like · 10,723 followersView post →
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PeptidePub
@PeptidePub · X
SELECT is the trial that changed Wegovy from a weight loss story into a cardiovascular-risk story.
Semaglutide cut major adverse cardiovascular events by 20% in people with obesity or overweight and established CVD, without diabetes.
PubMed: https://t.co/gJ5VNp7AuC
What
Is semaglutide now a heart medicine? What the 17,000‑person SELECT trial really showed.
In high‑risk people with heart disease and extra weight but no diabetes, this “skinny jab” also clearly lowered heart attacks and strokes over several years.
Weekly semaglutide 2.4 mg cut https://t.co/7zBRkAWOgb
Yikes.
The evidence he cited to warn you off a drug with 17,604 patients enrolled ten... Follow along if you please.
@SteveBennettMhP runs Clubwell, an app positioned around "real food" empowerment as the alternative to pharmaceutical obesity treatment.
His Clubwell members https://t.co/kD5dpqq6p9
Mar 13, 2026 · 5 likes · 1,034 followersView post →
TL
Tellit Likeitis
@Tellit007 · X
Yikes.
The evidence he cited to warn you off a drug with 17,604 patients enrolled ten... Following along if you please.
@SteveBennettMhP runs Clubwell, an app positioned around "real food" empowerment as the alternative to pharmaceutical obesity treatment.
His Clubwell https://t.co/kD5dpqq6p9
The least interesting metric in his post is the one attached to a 20% reduction in heart attacks and strokes across 17,604 patients.
His five "more interesting" ones are predictors. Weight is a lever.
Precious.
@dr_sumit_sharma runs a direct-to-consumer "precision metabolic https://t.co/sz62mhnZuX
@cwhogg @maxmarchione Here’s a couple just off the list I keep for clients:
- Wilding JPH, et al. (2021). Once-Weekly Semaglutide in Adults with Overweight or Obesity.
- Lincoff AM, et al. (2023). Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes.
-Perkovic V, et al. (2024).
Feb 25, 2026 · 7 likes · 1 share · 13,164 followersView post →
研T
研究キャリアサポート TACHIBANA
@tachibana_lab_ · X
【SELECT試験】
Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes
肥満・過体重かつASCVDを有する非糖尿病患者において、セマグルチド2.4 mgはMACEを20%低下させました。 心不全合併例でも、効果は一貫していました。
#研究キャリアサポート橘
96. Semaglutide 2.4 mg once weekly reduced major adverse cardiovascular events (MACE) compared with placebo in adults with overweight or obesity and established cardiovascular disease without diabetes, demonstrating cardiovascular benefit of GLP-1 receptor agonism beyond glycemic
All the trials and studies i have talked about
1. Wadden TA, Bailey TS, Billings LK, Davies M, Frias JP, Koroleva A, et al. Effect of subcutaneous semaglutide vs placebo as an adjunct to intensive behavioral therapy on body weight in adults with overweight or obesity: The STEP
Dec 20, 2025 · 4 likes · 9,064 followersView post →
KM
Kyle Kettler MD
@KyleKettlerMD · X
In Obesity
Best-in-class Diabetes Prevention
In patients without diabetes but with obesity, one of the important metabolic endpoints is how many patients end up with diabetes at the end of the trial compared to the placebo group. In a 2025 analysis, out of 1032 patients with https://t.co/Ml4RUQ1OCo
@KrutikaKuppalli @krutikakuppalli
Dr. Kuppalli,
With respect for your expertise in infectious diseases, I must challenge your dismissal of the FDA memo as "baseless misinformation." As a retired Canadian Marine SAR specialist who's spent years dissecting the data on these synthetic mRNA and
Nov 30, 2025 · 16 likes · 1 share · 14,071 followersView post →
GO
glp1observer
@glp1observer · X
3/4 The original results (a significant reduction in major adverse cardiovascular events) were reported (https://t.co/rzKNwKW6WN) in 2023 when the trial was complete and ultimately led to an FDA approval (https://t.co/C70Sbtua06) for a new indication.
RT @BoussageonR: @tolquen @Fraslin Tout d'abord, l'angioplastie n'était peut être pas indiquée
Ensuite, oui, il y a un essai chez des patie…
Oct 25, 2025 · 1 share · 30,294 followersView post →
BR
Boussageon Rémy
@BoussageonR · X
@tolquen @Fraslin Tout d'abord, l'angioplastie n'était peut être pas indiquée
Ensuite, oui, il y a un essai chez des patients non diabétique en prévention secondaire :
https://t.co/dLrN6kQzLF
Oct 25, 2025 · 1 like · 1 share · 655 followersView post →
Aug 26, 2025 · 20 likes · 271,030 followersView post →
C
Crémieux
@cremieuxrecueil · X
@bIiccy @RespectElves If that's your worry, then don't worry. GLP-1RAs directly help with heart stuff.
Check out the SELECT trial, for example: https://t.co/YGftJ0SREC https://t.co/tLZYSD0ngI
Aug 23, 2025 · 3 likes · 271,030 followersView post →
C
Crémieux
@cremieuxrecueil · X
@AnilMakam I've said that before as well, but it can't be taken as a hard-and-fast rule.
With GLP-1RAs, several RCTs have shown immediate divergence for different outcomes. For example, here's the composite cardiovascular endpoint in the SELECT RCT: https://t.co/YGftJ0Tpua https://t.co/CaHM8aS2qD
Aug 22, 2025 · 1 like · 271,030 followersView post →
JM
Jake Kelly MD
@jakekellymd · X
And yes—GLP-1s reduce more than just weight.
The SELECT trial showed:
RT @cremieuxrecueil: Essentially the whole chronic disease crisis can be substantially remedied, and knock-on benefits can be obtained, fro…
Jun 23, 2025 · 4 shares · 167 followersView post →
ML
Michael A. Lowry
@mlowry · X
RT @cremieuxrecueil: Essentially the whole chronic disease crisis can be substantially remedied, and knock-on benefits can be obtained, fro…
Jun 23, 2025 · 4 shares · 712 followersView post →
CM
Creolus Magnus
@Creolus_Magnus · X
RT @cremieuxrecueil: Essentially the whole chronic disease crisis can be substantially remedied, and knock-on benefits can be obtained, fro…
Jun 23, 2025 · 4 shares · 955 followersView post →
C
Crémieux
@cremieuxrecueil · X
Essentially the whole chronic disease crisis can be substantially remedied, and knock-on benefits can be obtained, from getting GLP-1RA prices down and access up.
Sources:
https://t.co/GTGczLASsF
https://t.co/YGftJ0Tpua
https://t.co/l9Ibpnglxl
Jun 23, 2025 · 34 likes · 4 shares · 271,030 followersView post →
Ü
Übermensch
@DocConTOC · X
RT @MediCasos: @Samuelc3c4adnd1 @AcidoRinon @BioTrustNut De nada:
https://t.co/Gni4ooDWMF
Jun 23, 2025 · 3 shares · 1,867 followersView post →
AC
Alejandro Castillo
@MediCasos · X
@Samuelc3c4adnd1 @AcidoRinon @BioTrustNut De nada:
https://t.co/Gni4ooDWMF
Jun 23, 2025 · 20 likes · 3 shares · 110,557 followersView post →
CP
Catalina Pogany
@pogany54 · X
RT @a_fisiolog57853: ENTREVISTA A DANIEL J. DRUCKER
¡¡¡A leer, zagales!!!
https://t.co/zev22XLKQ4
El ensayo SELECT: https://t.co/1AFq4iO…
ENTREVISTA A DANIEL J. DRUCKER
¡¡¡A leer, zagales!!!
https://t.co/zev22XLKQ4
El ensayo SELECT: https://t.co/1AFq4iOfcq https://t.co/YsfpMQf0EH
Jun 18, 2025 · 4 likes · 1 share · 3,817 followersView post →
BM
Brownian Motion
@cobrownell · X
@SCDawgin @PaulSkallas First of all, this counts as being tested in humans. Secondly, this drug, and more broadly this class of drugs, has been used in obese people for more than a few years. Third, allow me to introduce you to the SELECT trial which is one example https://t.co/Ijh4UoTCrA
Thank you, Dr. Manar Al Ghamdi ,for your insightful and evidence-based presentation on “Semaglutide and cardiovascular outcomes in obesity without diabetes”. Your clear articulation of the clinical implications and emerging data provided us with a valuable perspective on a https://t.co/1oSBFuemjs
May 17, 2025 · 3 likes · 1 share · 11,982 followersView post →
FO
FMhub.org
@Fmhub_org · X
Thank you, Dr. Manar Al Ghamdi ,for your insightful and evidence-based presentation on “Semaglutide and cardiovascular outcomes in obesity without diabetes”. Your clear articulation of the clinical implications and emerging data provided us with a valuable perspective on a https://t.co/85gX3InfRK
Bibliography
1. U.S. Food and Drug Administration. (2005, April 28). FDA approval letter: Byetta (exenatide) injection. https://t.co/DA8hsMAs3T
2. Gottlieb, S., & Johnson, B. (2022). Exenatide. In StatPearls (updated 2024). StatPearls Publishing.
3. Kristensen, S. L., Lee, M.
May 14, 2025 · 20 likes · 3 shares · 234,207 followersView post →
SQ
Stephan Quintin
@steph_quintin · X
@yoursimmo Meaningless, semeglutide (Ozempic) improve cardiovascular outcomes in ever RCT I’ve found, here’s one of 17000+ patients https://t.co/eG9hJ7BqKJ
@DustinSears9 @DrNadolsky I think that medicines that prevent heart attacks are good.
But to be fair I am a cardiologist, so I may be biased in this opinion.
https://t.co/jx9bPVqBgX
Pros and Cons per medcical AI of Ozempic (semaglutide):
Pros:
1. Glycemic Control: Semaglutide significantly reduces HbA1c levels, making it effective for managing type 2 diabetes.[1]
2. Weight Loss: It induces substantial weight loss in patients with type 2 diabetes and those
Mar 19, 2025 · 1 like · 1 share · 1,141 followersView post →
RS
Roger Santos
@rogersancto · X
@ourvcore https://t.co/Fz6oJWwpEy
importante revisar suas considerações sobre ser para diabetes. Como disse: droga comprovadamente eficaz, segura, estudos com benefícios robustos. NEJM, 2023
@perfaitement @HALLONSA @AsfyXi @Schmidtjnb Det är visat specifikt för fetma och är det första medlet som minskar ’all cause mortality’ hos överviktiga utan diabetes (och även stroke och ickedödliga hjärtinfarkter)
Finns flera studier nu men här är en av de första.
https://t.co/HPKMmKH1SA
Feb 26, 2025 · 1 like · 1,114 followersView post →
MD
MedicineMan Pharm.D
@MedicineMen99 · X
@TheMFingCOO @bava23 @LighthouseDPC @SaroshDin @drmoneymatters Problem Alan is obesity is more than just weight. Increase cardiovascular disease for example. Now we have data that says these drugs REDUCE heart attacks/strokes. So it’s more than losing 10-15%. What is the cost of a MI/stroke to a heath system?
https://t.co/p6sXkDCXAK
I read the thread, the comparison to Fen Fen and "shortcuts" is not the right message, look at this trial in people with obesity WITHOUT diabetes www.nejm.org/doi/full/10....
@GeneInvesting @WexCapital @DmitryKovalchuk @Anonym64382296 @A_May_MD so you think people with BMI in their 30s who have probably struggled with weight for most of their adult lives shouldn't take GLPs
I don't know what to say man. CVOT clearly disagrees with you there: https://t.co/TUWZl1Cxjx
Jan 30, 2025 · 2 likes · 9,351 followersView post →
Diet and exercise work well with prevention but suck at treatment.
Cf control group in the select study. https://t.co/Kb7vPR48M7 https://t.co/1YDOWxubw5
RT @EAPCPresident: 3 days to go before the EAPC Journal Club : read the publication "Semaglutide and Cardiovascular Outcomes in Obesity wit…
Jan 27, 2025 · 9 shares · 454 followersView post →
BA
Buket Akıncı
@PTBuketAkinci · X
RT @EAPCPresident: 3 days to go before the EAPC Journal Club : read the publication "Semaglutide and Cardiovascular Outcomes in Obesity wit…
Jan 27, 2025 · 9 shares · 280 followersView post →
SC
Silvia Castelletti
@SilCastelletti · X
RT @EAPCPresident: 3 days to go before the EAPC Journal Club : read the publication "Semaglutide and Cardiovascular Outcomes in Obesity wit…
Jan 27, 2025 · 9 shares · 8,668 followersView post →
EC
European Society of Cardiology
@escardio · X
RT @EAPCPresident: 3 days to go before the EAPC Journal Club : read the publication "Semaglutide and Cardiovascular Outcomes in Obesity wit…
Jan 27, 2025 · 9 shares · 149,502 followersView post →
DA
Dimitra Antonakaki
@DAntonakaki · X
RT @EAPCPresident: 3 days to go before the EAPC Journal Club : read the publication "Semaglutide and Cardiovascular Outcomes in Obesity wit…
Jan 27, 2025 · 9 shares · 403 followersView post →
E
EAPCPresident
@EAPCPresident · X
3 days to go before the EAPC Journal Club : read the publication "Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes" A. Michael Lincoff et al., N Engl J Med 2023;389:2221-2232, DOI: 10.1056/NEJMoa2307563 https://t.co/7WxadI9GlX https://t.co/GXsSnyZ6BI
Jan 27, 2025 · 14 likes · 9 shares · 2,531 followersView post →
را
ريم الكيلاني
@geneCulinary · X
RT @gbiondizoccai: Dont' miss the next EAPC Young Community Journal Club discussing the article by Lincoff et al entitled Semaglutide and C…
Dont' miss the next EAPC Young Community Journal Club discussing the article by Lincoff et al entitled Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes, scheduled for next week, January 30, from 17:00 to 18:00 CET myesc.escardio.org/esc_applicat...
Dont' miss the next EAPC Young Community Journal Club discussing the article by Lincoff et al entitled Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes, scheduled for next week, January 30, from 17:00 to 18:00 CET https://t.co/gWgQOuONke https://t.co/5SM840ABXS
Jan 23, 2025 · 2 likes · 1 share · 13,346 followersView post →
D
Docdu16
@docdu16.eurosky.social · Bluesky
Fil
1) Les résultats de l'étude SELECT : www.nejm.org/doi/full/10....
Join our webinar NOW on YouTube.
Part 2 of our top-rated studies in the field of nephrology and hypertensiology 2024.
Our final countdown!
youtu.be/rQFKyMoneQ8?...
Our guests:
Timotheus Speer
Matthias Girndt
Mariam Abu Tair
Join our webinar NOW on YouTube.
Part 2 of our top-rated studies in the field of nephrology and hypertensiology 2024.
Our final countdown!
https://t.co/ZWKe437WjN
Our guests:
Timotheus Speer
Matthias Girndt
Mariam Abu-Tair https://t.co/rJ653BjTtk
Jan 10, 2025 · 1 like · 1 share · 141 followersView post →
GH
Gunnar Henrik Heine
@gunnar_heine · X
Our final countdown 2024
@MarkusAtHome @MarcusSaemann @AntMarlies @AKronbichler
Best of Nephrology Hypertension II https://t.co/HafpmaSebV via @YouTube
Jan 10, 2025 · 3 likes · 1 share · 2,633 followersView post →
F
Fridgey
@LuckyFridge · X
@Pesamenteir0o @davebluntsmusic Looks like it helps with cardiovascular health
https://t.co/PP66sn2BKe
It also may have benefits for people with Alzhiemer's
https://t.co/Wv65jluF9C
So aside from basic side effects or a major reaction, looks like it's a pretty stable drug.
Here comes @NephJC Top 10 2024. We will follow with our ???? Top 7 on Friday!
https://t.co/b6ixY6vWh3
@MarcusSaemann @AKronbichler @AntMarlies https://t.co/WjmXNMbg8H
Jan 7, 2025 · 9 likes · 4 shares · 2,633 followersView post →
AL
Anthony B. Lennen
@abl57 · X
@ArtCandee I’m vaxed so I’m not a crazy anti- vax person. Had my pneumonia & flu shots 2 weeks ago. Please don’t tell me u think the CV trials were comparable to the SELECT trial.
https://t.co/2MZJfutKXu
Dec 27, 2024 · 1 share · 11,297 followersView post →
OM
Obesidades México
@Obesidades_mx · X
@ConscienHealth Fuentes:
-Conscien Health. 2024. Disponible en: https://t.co/sdhwetXopB
-Lincoff AM, et al. Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes. N Engl J Med. 2023.
Dec 27, 2024 · 3 likes · 1 share · 1,384 followersView post →
RP
Robert West, PhD ✝️
@westr · X
RT @ethanjweiss: It’s amazing to see the SELECT trial results. Blown away that there is a significant risk reduction in a group of patient…
Dec 17, 2024 · 44 shares · 19,335 followersView post →
AA
aldo aversa
@AldoAversa · X
RT @kevinnbass: Reference https://t.co/eBol4ZNJtL
Dec 14, 2024 · 1 share · 1,231 followersView post →
KM
Kevin Bass PhD MS
@kevinnbass · X
Reference https://t.co/eBol4ZNJtL
Dec 14, 2024 · 4 likes · 1 share · 170,194 followersView post →
Z
ZKForTre
@ZKForTre · X
6. If by benefits of the drug you mean weight, glycemic, cardiac, renal, vascular, and OA (among other forthcoming indications), the impacts are persistent:
https://t.co/mPQur3Hjzy
https://t.co/p4k8UTTuMQ
https://t.co/XNvGAzKWur
https://t.co/dvV9IH2EHE
https://t.co/BHSslgz3Xr
Dec 12, 2024 · 11 likes · 3,292 followersView post →
@MichaelMindrum @MithridatesMD @calleymeans Forgive me, but it looks like the trial was semaglutide vs placebo in non-diabetics and not ozempic vs. diet and lifestyle change in diabetics. And only followed for 39 months? https://t.co/hwMVK5fo5I
@Maesun196924 @MichaelMindrum @calleymeans Here’s the phase 3 that was done to date, others are due in the coming years as well
https://t.co/AXsCK67TY5
Semaglutide and cardiovascular outcomes in obesity without Diabetes (Select trial) è lo studio che ci parla degli effetti cv che Semaglutide ha sui soggetti obesi anche SENZA diabete. #itacarep #itacarepyoungcommunity https://t.co/gUA2Kgudvq
This paper published in the New England Journal of Medicine, showed GLP-1 drug reduced risk of death by 20%
https://t.co/KoESsl7qZb
$GLP1 https://t.co/pQfqFQXriF
Nov 23, 2024 · 2 likes · 1 share · 312 followersView post →
DV
Dogs&Viruses
@Craigster771 · X
@UrgentKarr @jackmurphylive @FitFounder How about you read the cardiovascular outcomes studies in actual humans (non-diabetics and diabetics)?
https://t.co/2QfrIf22at
https://t.co/34DfC0vd8h
@KetoCarnivore A rodent study is terrible news? Really?
You know that semaglutide improves cardiovascular outcomes in humans, right?
https://t.co/xHxf8CupxZ
@gameofchance3 @helen_mrow @Babygravy9 Except those on Ozempic see improvements in heart health vs those on placebo? https://t.co/W9SxNzEXuQ this is one of the largest trials I’ve been able to find and it clearly shows benefits with treatment vs without
Interesting read.
Repurposing GLP-1 agonists for Alcohol Use Disorder? Summarizing a large cohort Swedish study & REWHARD consortium.
1.? GLP-1 Agonists & Alcohol Use Disorder (AUD): Glucagon-like peptide-1 receptor agonists (GLP-1), such as semaglutide and liraglutide,
Nov 17, 2024 · 2 likes · 2,642 followersView post →
Oct 27, 2024 · 3 likes · 110,557 followersView post →
CB
Cannibal B. Buress
@StnbckTaughtMe · X
@thestoptv With preexisting cardiovascular disease and overweight or obesity but without diabetes, weekly subcutaneous semaglutide was superior to placebo in reducing the incidence of death from cardiovascular causes, nonfatal myocardial infarction/stroke.
https://t.co/i2voBaYzgn
With preexisting cardiovascular disease and overweight or obesity but without diabetes, weekly subcutaneous semaglutide was superior to placebo in reducing the incidence of death from cardiovascular causes, nonfatal myocardial infarction/stroke
https://t.co/i2voBaY1qP https://t.co/Nc7YHmYB8p
@thestoptv In patients with preexisting cardiovascular disease and overweight or obesity but without diabetes, weekly subcutaneous semaglutide at a dose of 2.4 mg was superior to placebo in reducing the incidence of death from cardiovascular causes…
https://t.co/i2voBaY1qP
@partsmath @newstart_2024 Claim: The muscle loss from semaglutide causes an age-related acceleration that will result in increased mortality.
Complete speculation in every part. And given that semaglutide reduces *ALL-CAUSE MORTALITY*, it's not every plausible speculation.
https://t.co/xHxf8CupxZ
@mgourmelon L'efficacité (perte de poids, baisse de mortalité spécifique, baisse des évènements CV) est prouvée par un essai de qualité. https://t.co/Ee3tFlv00Q on attend la mortalité totale (qui baisse avec le Zepbound)
@HomoDorkimus @partiallypro @CNLiberalism This is not true. There have been several large-scale clinical trials of Wegovy (the actual version of semaglutide approved for weight loss) finding a clear benefit on reduced heart, kidney disease, at least in ppl at higher risk. https://t.co/ATi7NqGOqF
Oct 4, 2024 · 1 like · 1 share · 2,900 followersView post →
F
ForensicPsyMD
@ForensicPsyMD · X
Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes | New England Journal of Medicine https://t.co/FhF7MxKak3
Steven Kahn
•Position: Advisory roles in several pharmaceutical companies
•Interests:
•Advisory board member for AltPep, Anji Pharmaceuticals, Boehringer Ingelheim, Eli Lilly, Intarcia, Merck, Novo Nordisk
•Manuscript Title: “Semaglutide and Cardiovascular Outcomes in
Only 12 of the 15 Study Authors have direct affiliation with the drugs manufacturer Novo Nordisk. However don’t worry they have all declared that despite their conflicts of interest they in fact have none to declare. ??♂️
So ask your doctor if Novo Nordisk’s GLP-1 receptor
In this study, the adverse heart effects started well before maximum weight loss, suggesting that it isn't *just* weight that is causing cardiovascular issues
https://t.co/iX6l1EWGYF
@msabouri Actually the largest trial on this population (SELECT trial) shows a higher SAE rate in the placebo.
https://t.co/r2qzu7FEe7 https://t.co/qfOKRxvRTf
Aug 24, 2024 · 4 likes · 24,964 followersView post →
AM
Avi Bitterman, MD
@AviBittMD · X
@philthatremains It actually does. Nothing you posted contradicts that. And the outcome based trials indicate that on balance not only do the benefits outweigh the side effects, its to the point where all cause mortality is higher without taking it.
https://t.co/r2qzu7F6oz https://t.co/BpA4dS2aTg
Aug 24, 2024 · 2 likes · 24,964 followersView post →
@elonmusk @cremieuxrecueil True. Amazing effects on overall health outcomes including overall death rate.
https://t.co/btY67AbZKh https://t.co/ScQSg5zfJQ
Evidence shows that Glp-1 drugs don’t just help you lose fat, but help with overall health, including reducing death rates:
source: https://t.co/btY67AbZKh https://t.co/G2uPbxABAY https://t.co/j0ydkKHgvf
@BohemianAtmosp1 Maybe you should read this instead https://t.co/fTap6fh4f4
Jul 25, 2024 · 1 like · 1 share · 114 followersView post →
DB
Darshan H Brahmbhatt
@Doctor_Darshan · X
The UK @MHRAgovuk has approved use of semaglutide as used in the groundbreaking SELECT trial. Will other territories follow suit? Will there be funding for this drug indication?
https://t.co/CIvLpcv8HZ https://t.co/3zxZp7JtZM
Semaglutide y resultados cardiovasculares en la obesidad sin diabetes
Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes | New England Journal of Medicine https://t.co/EvYAxDTTji
@realgirl_fieri I really think it might be something to discuss with your doctor! It’s not a celeb fad, it’s a heavily researched, life changing medication https://t.co/QyciAEmDHi
RT @PatrickHeizer: @mikex163 @StatisticUrban Guess you didn't read the paper, "Semaglutide and Cardiovascular Outcomes **in Obesity** witho…
May 29, 2024 · 2 shares · 815 followersView post →
FM
f musk
@Cousin2x · X
RT @TubmanRf2: @StatisticUrban Important caveat: it was studied in patients with preexisting CVD who had BMI of 27 or more. Remains to be s…
May 29, 2024 · 1 share · 1,034 followersView post →
FM
f musk
@Cousin2x · X
RT @PatrickHeizer: @mikex163 @StatisticUrban Guess you didn't read the paper, "Semaglutide and Cardiovascular Outcomes **in Obesity** witho…
May 29, 2024 · 2 shares · 1,034 followersView post →
H
HMPerson1
@HMPerson1 · X
@BorisBartlog @StatisticUrban there were similar results for all-cause mortality (but you'll have to get past the paywall to see that)
https://t.co/IYDA1Vl2U9
@ls_fin @catpoopburglar @StatisticUrban Are you sure? The paper said they studied patients with BMI or 27 or higher. Unless I'm looking at the wrong study?
https://t.co/h8VhWjYWoK
@StatisticUrban Important caveat: it was studied in patients with preexisting CVD who had BMI of 27 or more. Remains to be seen if it would have CVD protective properties in normal BMI patients. Given it's an obesity drug and obesity risk on CVD, I'm skeptical.
https://t.co/h8VhWjYWoK
May 28, 2024 · 15 likes · 1 share · 151 followersView post →
PH
Patrick Heizer
@PatrickHeizer · X
@mikex163 @StatisticUrban Guess you didn't read the paper, "Semaglutide and Cardiovascular Outcomes **in Obesity** without Diabetes."
The semaglutide group lost 10% of their body weight, on average. https://t.co/RowvS3ufXn
May 28, 2024 · 128 likes · 1 share · 12,942 followersView post →
AC
Almudena Castro Conde
@almucastro01 · X
2. El título del @nejm no ha podido ser más desafortunado:
Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes
TERRIBLE https://t.co/asT1BRA0ZP
May 25, 2024 · 9 likes · 16,992 followersView post →
B
Bert
@HenryRunamucker · X
@euthymiatech @shvogt Find me a trial like this one for ozempic which shows a statistically significant reduction in mortality for any psychiatric drug, for any condition. Randomized, large sample size... https://t.co/DBqMPKf7BJ
May 24, 2024 · 1 like · 2,130 followersView post →
L
LeithMotive
@leithmotive.bsky.social · Bluesky
There's a story about semaglutide that's headline news today. All well and good, but the paper it's based on was published about 6 months ago, so it's old news. I don't understand why only now is it being reported outside the specialist press?https://www.nejm.org/doi/full/10.1056/NEJMoa2307563
I assume you're talking about the same story as www.theguardian.com/science/arti..., which is about
www.nejm.org/doi/full/10.... - def peer reviewed.
'mass drugging of working class people?' WTF? What actually disturbs you?
(honestly, your post has strong disinfo/anti-vaxx vibes)
The paper in "NEJM", presented at the European Congress of Obesity, that the above "Guardian" article is based upon, & links to:
“Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes”
2/2
https://t.co/bpfbBFfewK
@whatabouttheken @AliceFromQueens @MSDOSUser @dhegertz In patients who were overweight and had pre-existing CVD, it reduced heart attacks, strokes, and death by ~20%
https://t.co/9nyHbCt78R
RT @redGDPS: Full text links @NEJM
Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes | NEJM https://t.co/lmlY1eGPkZ
Feb 29, 2024 · 3 shares · 737 followersView post →
EC
Enrique Carretero
@Enriq_Carretero · X
RT @redGDPS: Full text links @NEJM
Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes | NEJM https://t.co/lmlY1eGPkZ
Feb 29, 2024 · 3 shares · 664 followersView post →
EC
Enrique Carretero
@Enriq_Carretero · X
RT @redGDPS: Bibliografía en @PubMedOnline
https://t.co/0gGjM2qVuZ https://t.co/YVOYjDVhEC
Feb 29, 2024 · 2 shares · 665 followersView post →
RD
redGDPS Diabetes
@redGDPS · X
Bibliografía en @PubMedOnline
https://t.co/0gGjM2qVuZ https://t.co/YVOYjDVhEC
Feb 29, 2024 · 3 likes · 2 shares · 16,017 followersView post →
RD
redGDPS Diabetes
@redGDPS · X
Full text links @NEJM
Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes | NEJM https://t.co/lmlY1eGPkZ
Feb 29, 2024 · 4 likes · 3 shares · 16,017 followersView post →
OP
Oliver_Pl
@oliverpl.bsky.social · Bluesky
Studienbasierte Arztbriefempfehlungen: Semaglutid-Therapie (GLP1 Analoga) zur Risikoreduktion von kardiovaskulärem Tod bei Fettleibigkeit (BMI > 27 kg/m2) ohne Diabetes
SELECT-Studie: pubmed.ncbi.nlm.nih.gov/37952131/
Jan 26, 2024 · 5 shares · 1,390 followersView post →
MM
Michael Mindrum, MD
@MichaelMindrum · X
The landmark SELECT trial (semaglutide 2.4 mg) for patients with Obesity, CAD & no T2D. ⬇️MACE (RR ~20%); 2ndary end point "all cause mortality" significant. The immediate divergence of outcomes prior to significant weight loss is interesting . DOI: 10.1056/NEJMoa2307563 https://t.co/HagatMgnMF
Jan 26, 2024 · 5 likes · 10,760 followersView post →
GC
Gabriel Cabadiana
@gcabadianar · X
RT @sociedadSEEN:
Jan 26, 2024 · 5 shares · 114 followersView post →
O
ObesitySEEN
@ObesitySeen · X
RT @sociedadSEEN:
Jan 26, 2024 · 5 shares · 5,621 followersView post →
EG
Esteban Jódar Gimeno
@estebanjodar · X
RT @sociedadSEEN:
Jan 26, 2024 · 5 shares · 4,537 followersView post →
MP
Mari Carmen Porres
@LaPorres · X
RT @sociedadSEEN:
Jan 25, 2024 · 5 shares · 10,714 followersView post →
MB
María Ballesteros
@mdballesteros · X
RT @sociedadSEEN:
Jan 25, 2024 · 5 shares · 4,919 followersView post →
SS
Sociedad SEEN
@sociedadSEEN · X
Jan 25, 2024 · 20 likes · 5 shares · 17,874 followersView post →
LB
Leave it to Beaver
@espacetimeNOT · X
RT @deirdre_tobias: This was easily my favorite low-carb vs. low-fat trial of 2023:
https://t.co/we8uVZj3RV
Jan 24, 2024 · 6 shares · 1,204 followersView post →
PM
Philip Schauer, MD
@PSchauerMD · X
RT @DrRobertKushner: Enjoyed doing the Diabetes Core update podcast discussing #semaglutide and cardiovascular outcomes in #obesity without…
Jan 23, 2024 · 5 shares · 6,733 followersView post →
P
PuttingHealthFirst
@NeilSkolnik · X
RT @DrRobertKushner: Enjoyed doing the Diabetes Core update podcast discussing #semaglutide and cardiovascular outcomes in #obesity without…
Jan 22, 2024 · 5 shares · 1,358 followersView post →
OC
#obsm chat
@obsmchat · X
RT @DrRobertKushner: Enjoyed doing the Diabetes Core update podcast discussing #semaglutide and cardiovascular outcomes in #obesity without…
Jan 22, 2024 · 5 shares · 3,583 followersView post →
NE
NM Endocrinology
@NMEndocrinology · X
RT @DrRobertKushner: Enjoyed doing the Diabetes Core update podcast discussing #semaglutide and cardiovascular outcomes in #obesity without…
Jan 22, 2024 · 5 shares · 1,056 followersView post →
TK
Ted Kyle
@ConscienHealth · X
RT @DrRobertKushner: Enjoyed doing the Diabetes Core update podcast discussing #semaglutide and cardiovascular outcomes in #obesity without…
Jan 22, 2024 · 5 shares · 11,297 followersView post →
DK
Dr Robert Kushner
@DrRobertKushner · X
Enjoyed doing the Diabetes Core update podcast discussing #semaglutide and cardiovascular outcomes in #obesity without #diabetes: the #SELECT Trial. Listen here to the January podcast. @conscienhealth @NMendocrinology @AmDiabetesAssn @neilskolnik https://t.co/rxrHMnNGIR
Jan 22, 2024 · 11 likes · 5 shares · 4,188 followersView post →
MH
Medicina Interna HUB
@InternaHub · X
Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes. https://t.co/k0bbpNMI5T
#semaglutide #ozempic
Fonti:
Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes. N Engl J Med
The NANOGrav 15 yr Data Set: Evidence for a Gravitational-wave Background. Astrophys J Lett
Semantic Reconstruction of Continuous Language from Non-invasive Brain Recordings. Nat Neurosci https://t.co/odbAyYtq5q
N Engl J Med 2023; 389:2221-2232 DOI: 10.1056/NEJMoa2307563
痩せ薬で有名な糖尿病薬、GLP-1受容体作動薬が、糖尿病がない患者さんの心血管イベント抑制効果を示した論文。
超肥満の方には良さそうと言う結果かな。小太りな人に効果あるか興味あります。
@MariaJonsson1 Olaglig.
Åtminstone är det intressant att i en studie över cirka 3 år på icke-diabetes men överviktiga patienter med kända hjärt-kärlsjukdomar, minskade semaglutid något dödsfrekvensen eller hjärtinfarkt eller stroke (från 8,0 till 6,5%). https://t.co/9oBEIw8Bv8
Dec 19, 2023 · 10 shares · 635 followersView post →
NM
Northwestern Feinberg School of Medicine
@NUFeinbergMed · X
RT @NEJM: Year in Review: Top 10
Dec 19, 2023 · 10 shares · 18,421 followersView post →
MM
Manuel Méndez
@mendez_bailon · X
RT @AMAREVA_Madrid: Comentario de @pedropabloce sobre estudio SELECT Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes –…
Dec 19, 2023 · 3 shares · 7,770 followersView post →
HG
Henry Gaviria
@henrygav5 · X
RT @NEJM: Year in Review: Top 10
Dec 19, 2023 · 10 shares · 241 followersView post →
T
Travelgum
@travelgumm · X
RT @NEJM: Year in Review: Top 10 ? Posts of 2023
No. 3: Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes
Dec 19, 2023 · 10 shares · 308 followersView post →
MG
Mauro Goffo
@iamgoffo · X
RT @NEJM: Year in Review: Top 10
Dec 19, 2023 · 10 shares · 299 followersView post →
FP
Flotta Dura Senza Paura
@flottadura · X
RT @NEJM: Year in Review: Top 10
Dec 19, 2023 · 10 shares · 313 followersView post →
CM
Cristobal Morales
@CristobMorales · X
RT @NEJM: Year in Review: Top 10
Dec 19, 2023 · 10 shares · 17,805 followersView post →
N
NEJM
@NEJM · X
Year in Review: Top 10
Dec 19, 2023 · 47 likes · 10 shares · 1,042,131 followersView post →
MG
Marta Guillan
@Martaguillan · X
RT @AMAREVA_Madrid: Comentario de @pedropabloce sobre estudio SELECT Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes –…
Dec 19, 2023 · 3 shares · 998 followersView post →
TC
Teresa Gijon Conde
@TGijonConde · X
RT @AMAREVA_Madrid: Comentario de @pedropabloce sobre estudio SELECT Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes –…
Dec 19, 2023 · 3 shares · 1,059 followersView post →
AV
AMAREVA Riesgo Vascular
@AMAREVA_Madrid · X
Comentario de @pedropabloce sobre estudio SELECT Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes – AMAREVA – Asociación Madrileña de Riesgo y Enfermedad Vascular @Martaguillan @TGijonConde @chemachir @guso73 @mendez_bailon
https://t.co/4TCnc5cfHz https://t.co/08v4MWqBVG
Dec 19, 2023 · 5 likes · 3 shares · 466 followersView post →
LB
Luis Tobajas Belvís
@luisotobajas · X
Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes https://t.co/QOtvQoFR7t
RT @Amnesia2011: ال Ozympic و Wegovy مفيدان للقلب سواء أكنت سكرى أم لا
.....
هما يستخدمان لعلاج السكر ولكن ثبت أنهما رائعين أيضآ لخفض الوزن…
Dec 18, 2023 · 1 share · 9,059 followersView post →
A
Amnesia
@Amnesia2011 · X
ال Ozympic و Wegovy مفيدان للقلب سواء أكنت سكرى أم لا
.....
هما يستخدمان لعلاج السكر ولكن ثبت أنهما رائعين أيضآ لخفض الوزن الزائد
دراسة سابقة أثبتت أنهما يقللان أمراض القلب فى مرضى السكر
هذه الدراسة أثبتت أنهما يقللان مخاطر أمراض القلب أيضآ فى غير السكريين
https://t.co/2bTWY7juDM
Dec 18, 2023 · 1 share · 5,696 followersView post →
TH
Tom Hsiung
@TomHsiung · X
Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes | NEJM https://t.co/UhLYRn4YDz
Non-diabetic overweight/ obese pts with CV disease treated with #Semaglutide 2.4 mg/wk for 39.8 months: significantly reduced CVdeath/non-fatal MI/non-fatal CVA @NEJM @ShefUni_ClinMed @SheffieldHosp @Ahmed742Iqbal @BSHeartFailure #CardioTwitter https://t.co/vxtgCFB8B3
Dec 17, 2023 · 7 likes · 3 shares · 906 followersView post →
MH
Miguel Á. Huerta
@neurohuerta · X
Thorp HH. More questions than answers. Science. 2023;382(6676):1213. doi:10.1126/science.adn3693
Lincoff AM, Brown-Frandsen K, Colhoun HM, et al. Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes. N Engl J Med. 2023;389(24):2221-2232. doi:10.1056/NEJMoa2307563
Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes https://t.co/T34YiRWoqe
Dec 17, 2023 · 3 likes · 1 share · 5,172 followersView post →
TO
Tadeusz Osadnik
@TadeuszOsadnik · X
So much for obesity paradox… at least in this group of patients? N Engl J Med 2023; 389:2221-2232 DOI: 10.1056/NEJMoa2307563. Najnowsze doniesienia na zjeździe PTL przedstawione przez Prof. Małgorzata Trocha @PoLACongress @maciejbanach https://t.co/gwKVCRJtmp
Dec 17, 2023 · 17 likes · 3 shares · 201 followersView post →
PN
Peter Nash
@drpnash · X
Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes | NEJM https://t.co/B3ICcknBTM NNT 70 to reduce sudden death MI or stroke over 3 yrs 1 in 12 AEs
Dec 16, 2023 · 12 likes · 4 shares · 40,540 followersView post →
IB
irene breton
@irene_breton · X
RT @NEJM: Original Article: Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes (SELECT) https://t.co/sHpHQFO8VW
Editori…
Dec 16, 2023 · 78 shares · 1,410 followersView post →
LM
Leonardo Soto Muñoz
@LeonardoSotoMu · X
Semaglutide contra placebo en obesidad SIN diabetes. Observen las descontinuación del medicamento por eventos adverso GI
December 14, 2023
N Engl J Med 2023; 389:2221-2232
DOI: 10.1056/NEJMoa2307563 https://t.co/TuNkURa8qA
Dec 15, 2023 · 30 likes · 4 shares · 9,298 followersView post →
JF
Jonathan Fialkow
@JonFialkowMD · X
RT @NEJM: Original Article: Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes (SELECT) https://t.co/sHpHQFO8VW
Editori…
Dec 15, 2023 · 78 shares · 264 followersView post →
P
PcMEDProject
@PcMEDProject · X
RT @NEJM: Original Article: Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes (SELECT) https://t.co/sHpHQFO8VW
Editori…
Dec 15, 2023 · 78 shares · 136 followersView post →
GW
Geoff Wong
@DrGeoffWong · X
RT @NEJM: Original Article: Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes (SELECT) https://t.co/sHpHQFO8VW
Editori…
Dec 15, 2023 · 78 shares · 507 followersView post →
MS
MedEd Global Solutions
@global_meded · X
RT @NEJM: Original Article: Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes (SELECT) https://t.co/sHpHQFO8VW
Editori…
Dec 15, 2023 · 78 shares · 253 followersView post →
JR
José Antonio Rubio
@jarubiogarcia · X
RT @estebanjodar: Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes | NEJM https://t.co/iNvuanWihY
Dec 15, 2023 · 7 shares · 1,076 followersView post →
C
charmedbross
@charmedbross · X
RT @Nephro_Ivan: ???
Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes | NEJM https://t.co/mKb7al5NtW
セマグルチドの皮下注によって、糖尿病のない肥満患者の心血管イベントを減らす。NNT66、NNH 11である。リベルサス皮下注2.4mg(ウゴービ)の薬価は1週間で約10740円。
#GLP1阻害薬 #NEJM
Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes https://t.co/t5TJJLnHiC
Dec 2, 2023 · 2 likes · 4,138 followersView post →
Semaglutide reduced cardiovascular events by 20% in certain adults
Semaglutide reduced cardiovascular events by 20% in adults with overweight or obesity and established cardiovascular disease who do not have diabetes, according to new research.
https://t.co/gbBPp8bgWB
RT @davidcalle1390: Pues ahora sí #arGLP1 #Semaglutida #SELECT ❤️
Nov 14, 2023 · 54 shares · 421 followersView post →
JV
Julian P Villacastin
@jvillacastin · X
RT @davidcalle1390: Pues ahora sí #arGLP1 #Semaglutida #SELECT ❤️
Nov 14, 2023 · 54 shares · 23,325 followersView post →
MX
Medical Xpress
@medical_xpress · X
Semaglutide reduces #cardiovascularEvents by 20% in overweight or obese adults who don't have diabetes: Trial @nejm https://t.co/kzJHpsoQ29 https://t.co/gLualZ9Vbq
Nov 13, 2023 · 6 likes · 1 share · 172,924 followersView post →
循循
循環器病薬剤師ネットワーク(#循薬ネット)
@Cardio_Pharm_JP · X
https://t.co/UAydTfjioe
Nov 13, 2023 · 1 like · 4,400 followersView post →
Nov 12, 2023 · 40 likes · 3 shares · 7,281 followersView post →
ÁM
Área del Corazón del HUVV de Málaga
@ACorazonHUVV · X
RT @davidcalle1390: Pues ahora sí #arGLP1 #Semaglutida #SELECT ❤️
Nov 12, 2023 · 54 shares · 1,827 followersView post →
GP
Garcia Pinilla
@marlucale37 · X
RT @davidcalle1390: Pues ahora sí #arGLP1 #Semaglutida #SELECT ❤️
Nov 12, 2023 · 54 shares · 1,135 followersView post →
AO
Aleix Olivella
@AleixOlivella · X
RT @davidcalle1390: Pues ahora sí #arGLP1 #Semaglutida #SELECT ❤️
Nov 12, 2023 · 54 shares · 188 followersView post →
JD
Jenn Dowd
@drjenndowd.bsky.social · Bluesky
Super interesting clinical trial results for GLP-1 agonist semaglutide’s impact on cardiovascular outcomes in patients *without* diabetes- recently published in @nejm. #epitwitter #semaglutide #medtwitter
https://www.nejm.org/doi/full/10.1056/NEJMoa2307563
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RT @davidcalle1390: Pues ahora sí #arGLP1 #Semaglutida #SELECT ❤️
Nov 11, 2023 · 54 shares · 6,004 followersView post →
RM
Raquel Marzoa
@MarzoaRaquel · X
RT @davidcalle1390: Pues ahora sí #arGLP1 #Semaglutida #SELECT ❤️
Nov 11, 2023 · 54 shares · 1,335 followersView post →
AB
Alejandro Berenguel
@alberenguel · X
RT @davidcalle1390: Pues ahora sí #arGLP1 #Semaglutida #SELECT ❤️
Nov 11, 2023 · 54 shares · 2,409 followersView post →
TB
Teresa Blasco
@TeresaBlasco2 · X
RT @davidcalle1390: Pues ahora sí #arGLP1 #Semaglutida #SELECT ❤️
Nov 11, 2023 · 54 shares · 327 followersView post →
JM
Jaime Mazón
@JaimeMazonRuiz · X
Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes
⬇️Muerte CV IAM no fatal Ictus no fatal
⬇️Mortalidad cualquier causa
⬇️IAM no fatal
⬇️Nueva revascularizacion
⬇️Endpoint renal
https://t.co/S2wt27cvFR
doi:10.1056/NEJMoa2307563. } Comenta “GUÍA” si quieres nuestra Guía de Prescripción de Semaglutida en Obesidad, resumida y diseñada para médicos. ⚠️ ...
Semaglutide and Cardiovascular. Outcomes in Obesity without Diabetes. N Engl J Med. 2023 Dec 14;389(24):2221-2232. doi: 10.1056/NEJMoa2307563. Epub 2023 Nov. 11 ...