Multicenter Collaborative Study to Optimize Mass Spectrometry Workflows of Clinical Specimens.

Oliver Kardell, Christine von Toerne, Juliane Merl-Pham, Ann-Christine König, Marcel Blindert, Teresa K Barth, Julia Mergner, Christina Ludwig, Johanna Tüshaus, Stephan Eckert, Stephan A Müller, Stephan Breimann, Pieter Giesbertz, Alexander M Bernhardt, Lisa Schweizer

January 2024

Synopsis of Social media discussions

The collective discussions show strong enthusiasm and support, with mentions of innovative workflows, improvements through sharing protocols, and the importance of collaboration across labs. The tone uses words like 'amazing' and 'cool findings,' reflecting a positive outlook on the study's impact on clinical proteomics.

A
Agreement
 Strong agreement

The discussions uniformly show strong support for the research, highlighting its significance and positive outcomes, with phrases like 'amazing,' 'cool findings,' and 'integrating proteomics into clinical settings.'

I
Interest
 High level of interest

Participants are highly engaged and curious, evident from their focus on specifics like workflow optimization, sample preparation, and inter-laboratory collaboration.

E
Engagement
 Moderate level of engagement

Many posts delve into methodological details and the broader implications for clinical proteomics, indicating active engagement.

I
Impact
 High level of impact

The discussions emphasize the transformative potential of the study for clinical diagnostics and laboratory practices, using words like 'game changer' and referencing improvements in workflows and standardization.

Social Mentions

YouTube

1 Videos

Bluesky

1 Posts

Twitter

13 Posts

Blogs

2 Articles

Metrics

Video Views

23

Total Likes

19

Extended Reach

29,558

Social Features

17

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

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23 views

  • PreOmics
    @PreOmics (Twitter)

    Today, we celebrate #WorldHealthDay, and the efforts of the CLINSPECT-M consortium to integrate MS-based #proteomics into systems medicine by developing of standardized start-to-finish, fit-for-purpose workflows for clinical specimens. https://t.co/8KUapPQHoB https://t.co/mHhFwLBRl7
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    April 7, 2024

    1

  • Journal of Proteome Research
    @JProteomeRes (Twitter)


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    February 29, 2024

    1

    1

  • Journal of Proteome Research
    @JProteomeRes (Twitter)


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    January 25, 2024

    5

  • Roland M. Bruderer
    @RolandMBruderer (Twitter)

    RT @PreOmics: Are you planning on including clinical plasma or cerebrospinal fluid (CSF) samples in your MassSpec lab workflow? See what th…
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    January 22, 2024

    1

  • PreOmics
    @PreOmics (Twitter)

    Are you planning on including clinical plasma or cerebrospinal fluid (CSF) samples in your MassSpec lab workflow? See what the CLINSPECT-M consortium learned https://t.co/HFU6kmQ3th See the biological fluids sampleprep solution used in this publication https://t.co/0oZ3r5I7Vi https://t.co/xtyyj2uM3D
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    January 22, 2024

    1

    1

  • PreOmics
    @PreOmics (Twitter)

    The challenge:Find the best combo of #sampleprep technique, instrument setup &#proteomics software tools to handle clinical plasma & CSF samples. What won out in this real-life Munich six-centre round-robin study?(Spoiler: PreOmics kits did amazingly well) https://t.co/Me6Pj4S7L3 https://t.co/3JHXdGbFxN
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    December 19, 2023

    1

  • Journal of Proteome Research
    @JProteomeRes (Twitter)


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    December 14, 2023

    3

  • Alec Valenta
    @Alec_Valenta (Twitter)

    An interesting study comparing comparing proteomics workflows for plasma and CSF across labs. A lot to digest but some cool findings about differences in workflows and the importance of sharing knowledge between labs. https://t.co/wFiHLhir7E
    view full post

    December 8, 2023

    3

  • Jochen Schwenk
    @jochwenk (Twitter)

    RT @PastelBio: Multicenter Collaborative Study to Optimize Mass Spectrometry Workflows of Clinical Specimens https://t.co/iZDAdsDzCw --- #…
    view full post

    December 2, 2023

    1

  • Edu Chicano (@educhicano@bsky.social)
    @educhicano (Twitter)

    [ASAP] Multicenter Collaborative Study to Optimize Mass Spectrometry Workflows of Clinical Specimens https://t.co/nKbSkPcrDk
    view full post

    November 29, 2023

    1

  • Pastel BioScience
    @PastelBio (Twitter)

    Multicenter Collaborative Study to Optimize Mass Spectrometry Workflows of Clinical Specimens https://t.co/iZDAdsDzCw --- #proteomics #prot-paper https://t.co/nR4F466t33
    view full post

    November 29, 2023

    1

    1

  • PastelBio
    @pastelbio.bsky.social (Bluesky)

    Multicenter Collaborative Study to Optimize Mass Spectrometry Workflows of Clinical Specimens pubs.acs.org/doi/10.... --- #proteomics #prot-paper
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    November 29, 2023

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  • Proteomics Papers
    @pmxpapers (Twitter)

    Multicenter Collaborative Study to Optimize Mass Spectrometry Workflows of Clinical Specimens https://t.co/bJxVAa6KfA https://t.co/qTiDbXCLgM
    view full post

    November 28, 2023

  • BioMassSpec
    @realBioMassSpec (Twitter)

    Multicenter Collaborative Study to Optimize Mass Spectrometry Workflows of Clinical Specimens #JProteomeRes https://t.co/V7ykeEdZK3
    view full post

    November 28, 2023

Abstract Synopsis

  • The text discusses the integration of mass spectrometry-based proteomics into clinical settings, focusing on creating standardized workflows for handling clinical samples.
  • It outlines a research initiative involving six laboratories that conducted two round-robin studies using clinically relevant samples, including plasma and cerebrospinal fluid, to benchmark best practices in proteomics.
  • The collaborative effort led to improvements in methods and results between the two measurement rounds, highlighting the value of sharing protocols and expertise among laboratories for enhancing performance in proteomics studies.