PubHawk
January 2024 PMID 38015820

Multicenter Collaborative Study to Optimize Mass Spectrometry Workflows of Clinical Specimens.

Oliver Kardell, Christine von Toerne, Juliane Merl-Pham, Ann-Christine König, Marcel Blindert, Teresa K Barth, Julia Mergner, Christina Ludwig, Johanna Tüshaus, Stephan Eckert, Stephan A Müller, Stephan Breimann, Pieter Giesbertz, Alexander M Bernhardt, Lisa Schweizer

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Mentions

17
Peak: 5 in Nov 2023
across 4 sources since Nov 2023

Extended reach

29,558
potential audience

Total likes

19

Video views

23

Mentions per month

Nov 2023 – Sep 2025

Where it's discussed

  • X / Twitter13 posts
  • Blogs2 articles
  • Bluesky1 posts
  • YouTube1 videos

AI synopsis

What people are saying

The collective discussions show strong enthusiasm and support, with mentions of innovative workflows, improvements through sharing protocols, and the importance of collaboration across labs. The tone uses words like 'amazing' and 'cool findings,' reflecting a positive outlook on the study's impact on clinical proteomics.

AgreementStrong agreement

The discussions uniformly show strong support for the research, highlighting its significance and positive outcomes, with phrases like 'amazing,' 'cool findings,' and 'integrating proteomics into clinical settings.'

InterestHigh interest

Participants are highly engaged and curious, evident from their focus on specifics like workflow optimization, sample preparation, and inter-laboratory collaboration.

EngagementModerate engagement

Many posts delve into methodological details and the broader implications for clinical proteomics, indicating active engagement.

ImpactHigh impact

The discussions emphasize the transformative potential of the study for clinical diagnostics and laboratory practices, using words like 'game changer' and referencing improvements in workflows and standardization.

Abstract in brief

  • The text discusses the integration of mass spectrometry-based proteomics into clinical settings, focusing on creating standardized workflows for handling clinical samples.
  • It outlines a research initiative involving six laboratories that conducted two round-robin studies using clinically relevant samples, including plasma and cerebrospinal fluid, to benchmark best practices in proteomics.
  • The collaborative effort led to improvements in methods and results between the two measurement rounds, highlighting the value of sharing protocols and expertise among laboratories for enhancing performance in proteomics studies.
Read the full abstract

Top posts

Most liked on X and Bluesky
Journal of Proteome Research
@JProteomeRes · X

Jan 25, 2024 · 5 likes · 3,823 followers View post →
Journal of Proteome Research
@JProteomeRes · X

Dec 14, 2023 · 3 likes · 3,823 followers View post →
Alec Valenta
@Alec_Valenta · X

An interesting study comparing comparing proteomics workflows for plasma and CSF across labs. A lot to digest but some cool findings about differences in workflows and the importance of sharing knowledge between labs. https://t.co/wFiHLhir7E

Dec 8, 2023 · 3 likes · 102 followers View post →
Pastel BioScience
@PastelBio · X

Multicenter Collaborative Study to Optimize Mass Spectrometry Workflows of Clinical Specimens https://t.co/iZDAdsDzCw --- #proteomics #prot-paper https://t.co/nR4F466t33

Nov 29, 2023 · 1 like · 1 share · 5,377 followers View post →
Journal of Proteome Research
@JProteomeRes · X

Feb 29, 2024 · 1 like · 1 share · 3,823 followers View post →
Edu Chicano (@educhicano@bsky.social)
@educhicano · X

[ASAP] Multicenter Collaborative Study to Optimize Mass Spectrometry Workflows of Clinical Specimens https://t.co/nKbSkPcrDk

Nov 29, 2023 · 1 like · 1,346 followers View post →

All mentions

PreOmics
@PreOmics · X

Today, we celebrate #WorldHealthDay, and the efforts of the CLINSPECT-M consortium to integrate MS-based #proteomics into systems medicine by developing of standardized start-to-finish, fit-for-purpose workflows for clinical specimens. https://t.co/8KUapPQHoB https://t.co/mHhFwLBRl7

Apr 7, 2024 · 1 like · 942 followers View post →
Journal of Proteome Research
@JProteomeRes · X

Feb 29, 2024 · 1 like · 1 share · 3,823 followers View post →
Journal of Proteome Research
@JProteomeRes · X

Jan 25, 2024 · 5 likes · 3,823 followers View post →
Roland M. Bruderer
@RolandMBruderer · X

RT @PreOmics: Are you planning on including clinical plasma or cerebrospinal fluid (CSF) samples in your MassSpec lab workflow? See what th…

Jan 22, 2024 · 1 share · 940 followers View post →
PreOmics
@PreOmics · X

Are you planning on including clinical plasma or cerebrospinal fluid (CSF) samples in your MassSpec lab workflow? See what the CLINSPECT-M consortium learned https://t.co/HFU6kmQ3th See the biological fluids sampleprep solution used in this publication https://t.co/0oZ3r5I7Vi https://t.co/xtyyj2uM3D

Jan 22, 2024 · 1 like · 1 share · 942 followers View post →
PreOmics
@PreOmics · X

The challenge:Find the best combo of #sampleprep technique, instrument setup &#proteomics software tools to handle clinical plasma & CSF samples. What won out in this real-life Munich six-centre round-robin study?(Spoiler: PreOmics kits did amazingly well) https://t.co/Me6Pj4S7L3 https://t.co/3JHXdGbFxN

Dec 19, 2023 · 1 like · 942 followers View post →
Journal of Proteome Research
@JProteomeRes · X

Dec 14, 2023 · 3 likes · 3,823 followers View post →
Alec Valenta
@Alec_Valenta · X

An interesting study comparing comparing proteomics workflows for plasma and CSF across labs. A lot to digest but some cool findings about differences in workflows and the importance of sharing knowledge between labs. https://t.co/wFiHLhir7E

Dec 8, 2023 · 3 likes · 102 followers View post →
Jochen Schwenk
@jochwenk · X

RT @PastelBio: Multicenter Collaborative Study to Optimize Mass Spectrometry Workflows of Clinical Specimens https://t.co/iZDAdsDzCw --- #…

Dec 2, 2023 · 1 share · 954 followers View post →
Edu Chicano (@educhicano@bsky.social)
@educhicano · X

[ASAP] Multicenter Collaborative Study to Optimize Mass Spectrometry Workflows of Clinical Specimens https://t.co/nKbSkPcrDk

Nov 29, 2023 · 1 like · 1,346 followers View post →
Pastel BioScience
@PastelBio · X

Multicenter Collaborative Study to Optimize Mass Spectrometry Workflows of Clinical Specimens https://t.co/iZDAdsDzCw --- #proteomics #prot-paper https://t.co/nR4F466t33

Nov 29, 2023 · 1 like · 1 share · 5,377 followers View post →
PastelBio
@pastelbio.bsky.social · Bluesky

Multicenter Collaborative Study to Optimize Mass Spectrometry Workflows of Clinical Specimens pubs.acs.org/doi/10.... --- #proteomics #prot-paper

Nov 29, 2023 · 1 like · 2 shares View post →
Proteomics Papers
@pmxpapers · X

Multicenter Collaborative Study to Optimize Mass Spectrometry Workflows of Clinical Specimens https://t.co/bJxVAa6KfA https://t.co/qTiDbXCLgM

Nov 28, 2023 · 513 followers View post →
BioMassSpec
@realBioMassSpec · X

Multicenter Collaborative Study to Optimize Mass Spectrometry Workflows of Clinical Specimens #JProteomeRes https://t.co/V7ykeEdZK3

Nov 28, 2023 · 5,995 followers View post →