Mol Cancer December 2023 PMID 38093346

Dynamic altruistic cooperation within breast tumors.

Muhammad Sufyan Bin Masroni, Kee Wah Lee, Victor Kwan Min Lee, Siok Bian Ng, Chao Teng Law, Kok Siong Poon, Bernett Teck-Kwong Lee, Zhehao Liu, Yuen Peng Tan, Wee Ling Chng, Steven Tucker, Lynette Su-Mien Ngo, George Wai Cheong Yip, Min En Nga, Susan Swee Shan Hue

Mentions

32
Peak: 14 in Dec 2023
across 4 sources since Dec 2023

Extended reach

193,557
potential audience

Total likes

21

Video views

485

Mentions per month

Dec 2023 – Mar 2025

Where it's discussed

  • X / Twitter17 posts
  • News11 articles
  • YouTube2 videos
  • Blogs2 articles

AI synopsis

What people are saying

The group expresses strong interest and agreement with the idea that cancer cells can behave altruistically, as seen in phrases like 'potential cause of relapse' and 'tumors to be dynamic social systems.' The tone varies from scientific acknowledgment to playful mentions, but overall, the discussions recognize the importance of the research and its implications for understanding tumor behavior and treatment strategies.

AgreementModerate agreement

Most discussions acknowledge the significance of the findings, emphasizing the novelty of cancer cell cooperation and its role in tumor behavior.

InterestHigh interest

The topic of altruistic cancer cells and their social interactions within tumors sparks high curiosity among readers.

EngagementModerate engagement

Posts go beyond simple summaries, with some referencing related research and methods, showing moderate depth of discussion.

ImpactModerate impact

The discussions suggest this research could influence how we understand tumor dynamics and potential therapies, indicating a notable impact.

Abstract in brief

  • The study investigates altruistic behavior in breast cancer cells, traditionally viewed as self-serving, highlighting how this behavior can affect survival and chemoresistance within tumor environments.
  • Methods included microRNA profiling from patient blood samples and various in vitro and in vivo experiments, using techniques like flow cytometry and CRISPR to analyze cell behavior and interactions under chemotherapy.
  • Findings reveal that altruistic cancer cells secrete factors promoting survival in neighboring cells while also experiencing growth inhibition, regulated by specific microRNAs and signaling pathways, allowing them to persist and adapt despite their self-sacrificial actions.

Top posts

Most liked on X and Bluesky
Medical Xpress
@medical_xpress · X

#BreastCancer #cells' self-sacrificial behavior uncovered as potential cause of relapse @NUSingapore @biomedcentral https://t.co/YwoSrRX1Dy https://t.co/0Wu6yWeRUf

Dec 29, 2023 · 6 likes · 2 shares · 173,041 followers View post →
Sai Mun Leong
@Sai_Mun_Leong · X

What if cancer cells can behave altruistically, like social organisms

Dec 17, 2023 · 5 likes · 5 shares · 24 followers View post →
Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry · X

Dynamic altruistic cooperation within breast tumors “A minor population behave altruistically at a cost to itself producing a collective benefit for the tumor, suggesting tumors to be dynamic social systems governed by the same rules of cooperation in social organisms.”

Dec 29, 2023 · 4 likes · 18,409 followers View post →
N2CR
@N2CR_Singapore · X

Ho Ho Ho! Have you been naughty or nice this season? Dr Leong Sai Mun and team have been real nice by gifting us this a new paper on the dynamic altruistic cooperation within breast tumours! Read more: https://t.co/R3dKsXNIga

Dec 27, 2023 · 1 like · 1 share · 104 followers View post →
The()Graduate
@firexgamerx · X

RT @Sai_Mun_Leong: What if cancer cells can behave altruistically, like social organisms

Dec 18, 2023 · 5 shares · 491 followers View post →
The()Graduate
@firexgamerx · X

The cancer cell cooperation angle is also what we explored recently. We showed that a small subset of altruistic cancer cells secretes chemoprotective factors but at a cost to its own fitness. (2/n) https://t.co/s39CwhyQS2

Mar 27, 2025 · 491 followers View post →

All mentions

The()Graduate
@firexgamerx · X

The cancer cell cooperation angle is also what we explored recently. We showed that a small subset of altruistic cancer cells secretes chemoprotective factors but at a cost to its own fitness. (2/n) https://t.co/s39CwhyQS2

Mar 27, 2025 · 491 followers View post →
HealthyBuilds
@JamesSw70043542 · X

Dynamic altruistic cooperation within breast tumors https://t.co/gjTDXhfOST

Jan 9, 2024 · 16 followers View post →
HealthyBuilds
@JamesSw70043542 · X

Dynamic altruistic cooperation within breast tumors https://t.co/gjTDXhfOST

Jan 8, 2024 · 16 followers View post →
forum homewizard
@CoerForum · X

RT @richiecoer: DES CELLULES CANCÉREUSES PRÊTENT À SE SACRIFIER POUR LA SURVIE DES AUTRES https://t.co/MhtyAL9U9Y

Jan 7, 2024 · 1 share · 42 followers View post →
coste eric
@richiecoer · X

DES CELLULES CANCÉREUSES PRÊTENT À SE SACRIFIER POUR LA SURVIE DES AUTRES https://t.co/MhtyAL9U9Y

Jan 6, 2024 · 1 share · 75 followers View post →
Medical Xpress
@medical_xpress · X

#BreastCancer #cells' self-sacrificial behavior uncovered as potential cause of relapse @NUSingapore @biomedcentral https://t.co/YwoSrRX1Dy https://t.co/0Wu6yWeRUf

Dec 29, 2023 · 6 likes · 2 shares · 173,041 followers View post →
Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry · X

Dynamic altruistic cooperation within breast tumors “A minor population behave altruistically at a cost to itself producing a collective benefit for the tumor, suggesting tumors to be dynamic social systems governed by the same rules of cooperation in social organisms.”

Dec 29, 2023 · 4 likes · 18,409 followers View post →
Shuangyi Fan
@ShuangyiFan · X

RT @Sai_Mun_Leong: What if cancer cells can behave altruistically, like social organisms

Dec 29, 2023 · 5 shares · 1 followers View post →
Sai Mun Leong
@Sai_Mun_Leong · X

RT @N2CR_Singapore: Ho Ho Ho! Have you been naughty or nice this season? Dr Leong Sai Mun and team have been real nice by gifting us this…

Dec 28, 2023 · 1 share · 24 followers View post →
N2CR
@N2CR_Singapore · X

Ho Ho Ho! Have you been naughty or nice this season? Dr Leong Sai Mun and team have been real nice by gifting us this a new paper on the dynamic altruistic cooperation within breast tumours! Read more: https://t.co/R3dKsXNIga

Dec 27, 2023 · 1 like · 1 share · 104 followers View post →
Siok-Bian Ng, MBBS, FRCPA
@SiokBian_Ng · X

RT @Sai_Mun_Leong: What if cancer cells can behave altruistically, like social organisms

Dec 20, 2023 · 5 shares · 86 followers View post →
NJ
@Whois_NJ · X

RT @Sai_Mun_Leong: What if cancer cells can behave altruistically, like social organisms

Dec 20, 2023 · 5 shares · 15 followers View post →
ReaganEntigu
@reaganentigu · X

RT @Sai_Mun_Leong: What if cancer cells can behave altruistically, like social organisms

Dec 19, 2023 · 5 shares · 1 followers View post →
The()Graduate
@firexgamerx · X

RT @Sai_Mun_Leong: What if cancer cells can behave altruistically, like social organisms

Dec 18, 2023 · 5 shares · 491 followers View post →
Sai Mun Leong
@Sai_Mun_Leong · X

What if cancer cells can behave altruistically, like social organisms

Dec 17, 2023 · 5 likes · 5 shares · 24 followers View post →
ctSEQpapers
@ctSEQ_papers · X

PubMed_ Dynamic altruistic cooperation within breast tumors https://t.co/rMgOHHcHC5

Dec 14, 2023 · 161 followers View post →
viralecologypapers
@viraleco_papers · X

Dynamic altruistic cooperation within breast tumors https://t.co/pITtf7AZF5 https://t.co/RaUIv9UhV1

Dec 14, 2023 · 4 followers View post →