February 2024 PMID 38150260

Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission: A Secondary Analysis of the STRONG-HF Randomized Clinical Trial.

Gad Cotter, Benjamin Deniau, Beth Davison, Christopher Edwards, Marianna Adamo, Mattia Arrigo, Marianela Barros, Jan Biegus, Jelena Celutkiene, Kamile Cerlinskaite-Bajore, Ovidiu Chioncel, Alain Cohen-Solal, Albertino Damasceno, Rafael Diaz, Gerasimos Filippatos

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Mentions

63
Peak: 25 in Dec 2023
across 5 sources since Dec 2023

Extended reach

477,144
potential audience

Total likes

158

Video views

134

Mentions per month

Dec 2023 – Apr 2024

Where it's discussed

  • X / Twitter53 posts
  • News4 articles
  • YouTube2 videos
  • Facebook2 posts
  • Blogs2 articles

AI synopsis

What people are saying

The discussions highlight the importance of achieving higher doses of heart failure medications within a short period, using terms like 'all efforts should be made' and 'rapid uptitration,' reflecting strong support and perceived significance. The tone and context show excitement for the potential impact on patient outcomes and clinical management, emphasizing both the scientific importance and practical implications of the findings.

AgreementModerate agreement

Most discussions support the importance of rapidly uptitrating heart failure medications, indicating agreement with the study's findings.

InterestHigh interest

Posts show high interest, with many emphasizing the significance of the research and referencing specific trial names and clinical practices.

EngagementModerate engagement

Comments refer to the methods, results, and implications, demonstrating moderate to deep engagement with the topic.

ImpactHigh impact

The widespread focus on optimizing treatment suggests this publication could influence clinical guidelines and practice changes.

Abstract in brief

  • The study analyzed how quickly and effectively patients with acute heart failure (AHF) received optimized doses of heart failure medications after hospital discharge, aiming for full doses within 2 weeks.
  • Patients who achieved higher doses of medications like RAS inhibitors and mineralocorticoid receptor antagonists generally had better outcomes, but those with lower blood pressure and more symptoms were less likely to reach optimal doses.
  • The analysis also looked at 180-day readmission or death rates and quality of life changes, emphasizing the importance of quickly reaching guideline-recommended medication doses for improving patient outcomes.]

Top posts

Most liked on X and Bluesky
JAMA Cardiology
@JAMACardio · X

When patients with acute heart failure can tolerate higher doses of guideline-directed medical therapy, results suggest that all efforts should be made to rapidly uptitrate to optimal doses of the 3 and (likely) 4 pillars of HF medications. https://t.co/OR8WefrTCM

Dec 28, 2023 · 37 likes · 12 shares · 47,808 followers View post →
JAMA Cardiology
@JAMACardio · X

When patients with acute heart failure can tolerate higher doses of guideline-directed medical therapy, results suggest that all efforts should be made to rapidly uptitrate to optimal doses of the 3 and (likely) 4 pillars of HF medications. https://t.co/29KsHWR027

Feb 17, 2024 · 31 likes · 7 shares · 47,808 followers View post →
Gregg Fonarow MD
@gcfmd · X

Among patients with AHF randomly assigned to high-intensity care, achieving higher doses of HF GDMT within 2 wks after

Dec 27, 2023 · 26 likes · 6 shares · 11,812 followers View post →
pinacol
@pinacol · X

【追加解析: STRONG-HF】急性心不全患者において、GDMT(RAS阻害薬、β遮断薬およびMRA)の最適な投与量に対する投与量の割合の平均値の10%の増加は、180日心不全再入院または全原因死亡の減少と関連した。90日時点のQoLはGDMTの投与量が多い患者でより改善が見られた。 #ペ読 https://t.co/NfO23lWl6x

Dec 30, 2023 · 13 likes · 1,617 followers View post →
The Heart
@ZHeart11768530 · X

Feb 17, 2024 · 10 likes · 4 shares · 32,840 followers View post →
DARMPO Hôpital Saint Louis
@dar_louis · X

Dec 28, 2023 · 9 likes · 6 shares · 300 followers View post →

All mentions

東北大学 循環器内科
@cardio_tu · X

2 min cardiology(臨床論文、担当:井上巧) Optimization of Evidence-Based Heart failure Medications After an Acute Heart Failure Admission Gad Cotter et al. JAMA Cardiol. 2024; 9(2): 114-124 https://t.co/9ZeEYzftFN →

Apr 16, 2024 · 1,318 followers View post →
キャンプ剤師【循腎児】
@zaishicamp · X

Strong-HFはフルテキストなんとかもらって読んでたけど、アクセスは制限、、、Strong-HFの二次分析の論文はフリーアクセスやったし、こっちはこっちで分かりやすかった! Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission https://t.co/HxJ8VqQIFy

Mar 23, 2024 · 8 likes · 202 followers View post →
SFC - Société Française de Cardiologie
@SFCardio · X

Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission - A Secondary Analysis of the STRONG-HF Randomized Clinical Trial

Feb 21, 2024 · 4,709 followers View post →
Chidambara .ML.
@chidambara09 · X

RT @medicalport_app: Have you already listened to the podcast Best of the Month – January 2024? This episode turns the top papers publishe…

Feb 20, 2024 · 2 shares · 11,744 followers View post →
R Ladeiras Lopes
@rladeiraslopes · X

RT @medicalport_app: Have you already listened to the podcast Best of the Month – January 2024? This episode turns the top papers publishe…

Feb 20, 2024 · 2 shares · 5,419 followers View post →
Medical Portfolio APP
@medicalport_app · X

Have you already listened to the podcast Best of the Month – January 2024? This episode turns the top papers published in January into captivating conversations with our scientific team!

Feb 20, 2024 · 2 likes · 2 shares · 182 followers View post →
Tom Hsiung
@TomHsiung · X

Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission https://t.co/YX5PoSknpz

Feb 19, 2024 · 462 followers View post →
JORGE FERNANDEZ
@drjorfer · X

Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission: A Secondary Analysis of the STRONG-HF Randomized Clinical Trial | Cardiology | JAMA Cardiology | JAMA Network

Feb 18, 2024 · 2 likes · 1,019 followers View post →
WadhwaMD
@wadhwamd · X

RT @ZHeart11768530:

Feb 18, 2024 · 4 shares · 234 followers View post →
adagajak
@zftjhust · X

RT @ZHeart11768530:

Feb 17, 2024 · 4 shares · 202 followers View post →
JorgeEdoChava75
@QicenoJorge · X

RT @ZHeart11768530:

Feb 17, 2024 · 4 shares · 998 followers View post →
Maria Hazel Cohan, DNP, AGACNP-BC, AACC
@mcvhaze · X

Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission https://t.co/ON3dpEdySn

Feb 17, 2024 · 134 followers View post →
Hany Ragy
@Hragy · X

RT @JAMACardio: When patients with acute heart failure can tolerate higher doses of guideline-directed medical therapy, results suggest tha…

Feb 17, 2024 · 7 shares · 80,389 followers View post →
Alexandre Mebazaa
@AlexMebazaa · X

RT @JAMACardio: When patients with acute heart failure can tolerate higher doses of guideline-directed medical therapy, results suggest tha…

Feb 17, 2024 · 7 shares · 1,488 followers View post →
christina dunbar matos
@MatosDunbar · X

RT @JAMACardio: When patients with acute heart failure can tolerate higher doses of guideline-directed medical therapy, results suggest tha…

Feb 17, 2024 · 7 shares · 64 followers View post →
Sintayehu Abebe
@sinta_gf · X

RT @ZHeart11768530:

Feb 17, 2024 · 4 shares · 451 followers View post →
The Heart
@ZHeart11768530 · X

Feb 17, 2024 · 10 likes · 4 shares · 32,840 followers View post →
Brian P. Rose, PA-C MPH AACC
@Brian_RosePA · X

RT @JAMACardio: When patients with acute heart failure can tolerate higher doses of guideline-directed medical therapy, results suggest tha…

Feb 17, 2024 · 7 shares · 311 followers View post →
Basel Alenazy | باسل العنزي
@Baselalanazi6 · X

RT @JAMACardio: When patients with acute heart failure can tolerate higher doses of guideline-directed medical therapy, results suggest tha…

Feb 17, 2024 · 7 shares · 465 followers View post →
Rene Rodriguez
@renecardio4 · X

RT @JAMACardio: When patients with acute heart failure can tolerate higher doses of guideline-directed medical therapy, results suggest tha…

Feb 17, 2024 · 7 shares · 1,163 followers View post →
Gregg Fonarow MD
@gcfmd · X

RT @JAMACardio: When patients with acute heart failure can tolerate higher doses of guideline-directed medical therapy, results suggest tha…

Feb 17, 2024 · 7 shares · 11,812 followers View post →
JAMA Cardiology
@JAMACardio · X

When patients with acute heart failure can tolerate higher doses of guideline-directed medical therapy, results suggest that all efforts should be made to rapidly uptitrate to optimal doses of the 3 and (likely) 4 pillars of HF medications. https://t.co/29KsHWR027

Feb 17, 2024 · 31 likes · 7 shares · 47,808 followers View post →
Chidambara .ML.
@chidambara09 · X

RT @medicalport_app:

Feb 13, 2024 · 1 share · 11,744 followers View post →
Medical Portfolio APP
@medicalport_app · X

Feb 13, 2024 · 1 share · 182 followers View post →
SFC - Société Française de Cardiologie
@SFCardio · X

Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission - A Secondary Analysis of the STRONG-HF Randomized Clinical Trial

Jan 9, 2024 · 4,709 followers View post →
Villa
@pachovilla_11 · X

Siempre buscar dosis máximas toleradas Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission https://t.co/Z5GuZ4x93h

Jan 2, 2024 · 1 like · 153 followers View post →
Daniel Isaza
@danielisazamd · X

Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission: A Secondary Analysis of the STRONG-HF Randomized Clinical Trial | Cardiology | JAMA Cardiology | JAMA Network https://t.co/IbsCHqcZVC

Jan 2, 2024 · 3 likes · 1 share · 947 followers View post →
Maria Hazel Cohan, DNP, AGACNP-BC, AACC
@mcvhaze · X

Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission https://t.co/AxVG5LFDVk

Jan 2, 2024 · 134 followers View post →
Indian Heart Association
@theindianheart · X

Full article open access #FOAMed : https://t.co/SZGfFEPUa5

Dec 31, 2023 · 2 likes · 1,117 followers View post →
pinacol
@pinacol · X

【追加解析: STRONG-HF】急性心不全患者において、GDMT(RAS阻害薬、β遮断薬およびMRA)の最適な投与量に対する投与量の割合の平均値の10%の増加は、180日心不全再入院または全原因死亡の減少と関連した。90日時点のQoLはGDMTの投与量が多い患者でより改善が見られた。 #ペ読 https://t.co/NfO23lWl6x

Dec 30, 2023 · 13 likes · 1,617 followers View post →
JORGE FERNANDEZ
@drjorfer · X

Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission: A Secondary Analysis of the STRONG-HF Randomized Clinical Trial | Cardiology | JAMA Cardiology | JAMA Network✅☑️✅☑️ https://t.co/Ry5SDsnBDA

Dec 29, 2023 · 1,019 followers View post →
Tom Hsiung
@TomHsiung · X

Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission https://t.co/4LzFKHd20u

Dec 29, 2023 · 462 followers View post →
Dr. Martha Gulati ♥️
@DrMarthaGulati · X

RT @JAMACardio: When patients with acute heart failure can tolerate higher doses of guideline-directed medical therapy, results suggest tha…

Dec 28, 2023 · 12 shares · 64,732 followers View post →
Daniele Rodolico
@DanieleRodolico · X

RT @JAMACardio: When patients with acute heart failure can tolerate higher doses of guideline-directed medical therapy, results suggest tha…

Dec 28, 2023 · 12 shares · 417 followers View post →
Audrey De Jong
@audreydejongMD · X

RT @dar_louis:

Dec 28, 2023 · 6 shares · 1,299 followers View post →
Dr. Martha Gulati ♥️
@DrMarthaGulati · X

RT @gcfmd: Among patients with AHF randomly assigned to high-intensity care, achieving higher doses of HF GDMT within 2 wks after

Dec 28, 2023 · 6 shares · 64,732 followers View post →
Gregg Fonarow MD
@gcfmd · X

RT @JAMACardio: When patients with acute heart failure can tolerate higher doses of guideline-directed medical therapy, results suggest tha…

Dec 28, 2023 · 12 shares · 11,812 followers View post →
JAMA Cardiology
@JAMACardio · X

When patients with acute heart failure can tolerate higher doses of guideline-directed medical therapy, results suggest that all efforts should be made to rapidly uptitrate to optimal doses of the 3 and (likely) 4 pillars of HF medications. https://t.co/OR8WefrTCM

Dec 28, 2023 · 37 likes · 12 shares · 47,808 followers View post →
Dépret François
@depret_francois · X

RT @dar_louis:

Dec 28, 2023 · 6 shares · 105 followers View post →
i-micro Trial
@TrialMicro · X

RT @dar_louis:

Dec 28, 2023 · 6 shares · 59 followers View post →
Alexandre Mebazaa
@AlexMebazaa · X

RT @gcfmd: Among patients with AHF randomly assigned to high-intensity care, achieving higher doses of HF GDMT within 2 wks after

Dec 28, 2023 · 6 shares · 1,488 followers View post →
Alexandre Mebazaa
@AlexMebazaa · X

RT @dar_louis:

Dec 28, 2023 · 6 shares · 1,488 followers View post →
JorgeEdoChava75
@QicenoJorge · X

RT @FormigaFrancesc: Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission https://t.co/Rat9rSc0y…

Dec 28, 2023 · 1 share · 998 followers View post →
Emmanuel Dudoignon
@EDudoignon · X

RT @dar_louis:

Dec 28, 2023 · 6 shares · 115 followers View post →
Matthieu Jabaudon
@mj0b · X

RT @dar_louis:

Dec 28, 2023 · 6 shares · 896 followers View post →
DARMPO Hôpital Saint Louis
@dar_louis · X

Dec 28, 2023 · 9 likes · 6 shares · 300 followers View post →
Francesc Formiga
@FormigaFrancesc · X

Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission https://t.co/Rat9rSc0yS @IcyfaSemi @Medtorek @SABOURETCardio

Dec 28, 2023 · 4 likes · 1 share · 1,947 followers View post →
Valva Mitralis
@Mitrovalvology · X

RT @gcfmd: Among patients with AHF randomly assigned to high-intensity care, achieving higher doses of HF GDMT within 2 wks after

Dec 27, 2023 · 6 shares · 4,135 followers View post →
Ovidio García
@ovidiogarciav · X

RT @gcfmd: Among patients with AHF randomly assigned to high-intensity care, achieving higher doses of HF GDMT within 2 wks after

Dec 27, 2023 · 6 shares · 3,519 followers View post →
Sintayehu Abebe
@sinta_gf · X

RT @ZHeart11768530: Optimization of Evidence-Based #HF drugs After an #AHF Admission: A 2ry Analysis of STRONG-HF Trial ✅ When pts tolera…

Dec 27, 2023 · 1 share · 451 followers View post →
The Heart
@ZHeart11768530 · X

Optimization of Evidence-Based #HF drugs After an #AHF Admission: A 2ry Analysis of STRONG-HF Trial ✅ When pts tolerate higher doses of GDMT, all efforts should be made to rapidly uptitrate to optimal doses of the 3 & (likely) 4 pillars of HF drugs https://t.co/hxYuCscWhk https://t.co/wa3TBaOGKq

Dec 27, 2023 · 8 likes · 1 share · 32,840 followers View post →
Sherif
@Sherifdotcom · X

RT @gcfmd: Among patients with AHF randomly assigned to high-intensity care, achieving higher doses of HF GDMT within 2 wks after

Dec 27, 2023 · 6 shares · 130 followers View post →
Gregg Fonarow MD
@gcfmd · X

Among patients with AHF randomly assigned to high-intensity care, achieving higher doses of HF GDMT within 2 wks after

Dec 27, 2023 · 26 likes · 6 shares · 11,812 followers View post →