Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission: A Secondary Analysis of the STRONG-HF Randomized Clinical Trial.

Gad Cotter, Benjamin Deniau, Beth Davison, Christopher Edwards, Marianna Adamo, Mattia Arrigo, Marianela Barros, Jan Biegus, Jelena Celutkiene, Kamile Cerlinskaite-Bajore, Ovidiu Chioncel, Alain Cohen-Solal, Albertino Damasceno, Rafael Diaz, Gerasimos Filippatos

February 2024

Synopsis of Social media discussions

The discussions highlight the importance of achieving higher doses of heart failure medications within a short period, using terms like 'all efforts should be made' and 'rapid uptitration,' reflecting strong support and perceived significance. The tone and context show excitement for the potential impact on patient outcomes and clinical management, emphasizing both the scientific importance and practical implications of the findings.

A
Agreement
 Moderate agreement

Most discussions support the importance of rapidly uptitrating heart failure medications, indicating agreement with the study's findings.

I
Interest
 High level of interest

Posts show high interest, with many emphasizing the significance of the research and referencing specific trial names and clinical practices.

E
Engagement
 Moderate level of engagement

Comments refer to the methods, results, and implications, demonstrating moderate to deep engagement with the topic.

I
Impact
 High level of impact

The widespread focus on optimizing treatment suggests this publication could influence clinical guidelines and practice changes.

Social Mentions

YouTube

2 Videos

Facebook

2 Posts

Twitter

53 Posts

Blogs

2 Articles

News

4 Articles

Metrics

Video Views

134

Total Likes

158

Extended Reach

477,144

Social Features

63

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

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101 views

Rapid Uptitration of Heart Failure Medications Post-Hospitalization

Rapid Uptitration of Heart Failure Medications Post-Hospitalization

The STRONG-HF trial explored the rapid uptitration of guideline-directed heart failure therapy (GDMT) after hospitalization. The study found over 90% of patients achieved optimal GDMT doses in two weeks, leading to reduced readmission rates and improved quality of life.

Bishnu Subedi

April 15, 2024

33 views

  • 東北大学 循環器内科
    @cardio_tu (Twitter)

    2 min cardiology（臨床論文、担当：井上巧） Optimization of Evidence-Based Heart failure Medications After an Acute Heart Failure Admission Gad Cotter et al. JAMA Cardiol. 2024; 9(2): 114-124 https://t.co/9ZeEYzftFN →
    view full post

    April 16, 2024

  • キャンプ剤師【循腎児】
    @zaishicamp (Twitter)

    Strong-HFはフルテキストなんとかもらって読んでたけど、アクセスは制限、、、Strong-HFの二次分析の論文はフリーアクセスやったし、こっちはこっちで分かりやすかった！ Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission https://t.co/HxJ8VqQIFy
    view full post

    March 23, 2024

    8

  • SFC - Société Française de Cardiologie
    @SFCardio (Twitter)

    Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission - A Secondary Analysis of the STRONG-HF Randomized Clinical Trial
    view full post

    February 21, 2024

  • Chidambara .ML.
    @chidambara09 (Twitter)

    RT @medicalport_app: Have you already listened to the podcast Best of the Month – January 2024? This episode turns the top papers publishe…
    view full post

    February 20, 2024

    2

  • R Ladeiras Lopes
    @rladeiraslopes (Twitter)

    RT @medicalport_app: Have you already listened to the podcast Best of the Month – January 2024? This episode turns the top papers publishe…
    view full post

    February 20, 2024

    2

  • Medical Portfolio APP
    @medicalport_app (Twitter)

    Have you already listened to the podcast Best of the Month – January 2024? This episode turns the top papers published in January into captivating conversations with our scientific team!
    view full post

    February 20, 2024

    2

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  • Tom Hsiung
    @TomHsiung (Twitter)

    Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission https://t.co/YX5PoSknpz
    view full post

    February 19, 2024

  • JORGE FERNANDEZ
    @drjorfer (Twitter)

    Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission: A Secondary Analysis of the STRONG-HF Randomized Clinical Trial | Cardiology | JAMA Cardiology | JAMA Network
    view full post

    February 18, 2024

    2

  • WadhwaMD
    @wadhwamd (Twitter)

    RT @ZHeart11768530:
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    February 18, 2024

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  • adagajak
    @zftjhust (Twitter)

    RT @ZHeart11768530:
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    February 17, 2024

    4

  • JorgeEdoChava75
    @QicenoJorge (Twitter)

    RT @ZHeart11768530:
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    February 17, 2024

    4

  • Maria Hazel Cohan, DNP, AGACNP-BC, AACC
    @mcvhaze (Twitter)

    Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission https://t.co/ON3dpEdySn
    view full post

    February 17, 2024

  • Hany Ragy
    @Hragy (Twitter)

    RT @JAMACardio: When patients with acute heart failure can tolerate higher doses of guideline-directed medical therapy, results suggest tha…
    view full post

    February 17, 2024

    7

  • Alexandre Mebazaa
    @AlexMebazaa (Twitter)

    RT @JAMACardio: When patients with acute heart failure can tolerate higher doses of guideline-directed medical therapy, results suggest tha…
    view full post

    February 17, 2024

    7

  • christina dunbar matos
    @MatosDunbar (Twitter)

    RT @JAMACardio: When patients with acute heart failure can tolerate higher doses of guideline-directed medical therapy, results suggest tha…
    view full post

    February 17, 2024

    7

  • Sintayehu Abebe
    @sinta_gf (Twitter)

    RT @ZHeart11768530:
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    February 17, 2024

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  • The Heart
    @ZHeart11768530 (Twitter)


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    February 17, 2024

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    4

  • Brian P. Rose, PA-C MPH AACC
    @Brian_RosePA (Twitter)

    RT @JAMACardio: When patients with acute heart failure can tolerate higher doses of guideline-directed medical therapy, results suggest tha…
    view full post

    February 17, 2024

    7

  • Basel Alenazy | باسل العنزي
    @Baselalanazi6 (Twitter)

    RT @JAMACardio: When patients with acute heart failure can tolerate higher doses of guideline-directed medical therapy, results suggest tha…
    view full post

    February 17, 2024

    7

  • Rene Rodriguez
    @renecardio4 (Twitter)

    RT @JAMACardio: When patients with acute heart failure can tolerate higher doses of guideline-directed medical therapy, results suggest tha…
    view full post

    February 17, 2024

    7

  • Gregg Fonarow MD
    @gcfmd (Twitter)

    RT @JAMACardio: When patients with acute heart failure can tolerate higher doses of guideline-directed medical therapy, results suggest tha…
    view full post

    February 17, 2024

    7

  • JAMA Cardiology
    @JAMACardio (Twitter)

    When patients with acute heart failure can tolerate higher doses of guideline-directed medical therapy, results suggest that all efforts should be made to rapidly uptitrate to optimal doses of the 3 and (likely) 4 pillars of HF medications. https://t.co/29KsHWR027
    view full post

    February 17, 2024

    31

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  • Chidambara .ML.
    @chidambara09 (Twitter)

    RT @medicalport_app:
    view full post

    February 13, 2024

    1

  • Medical Portfolio APP
    @medicalport_app (Twitter)


    view full post

    February 13, 2024

    1

  • SFC - Société Française de Cardiologie
    @SFCardio (Twitter)

    Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission - A Secondary Analysis of the STRONG-HF Randomized Clinical Trial
    view full post

    January 9, 2024

  • Villa
    @pachovilla_11 (Twitter)

    Siempre buscar dosis máximas toleradas Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission https://t.co/Z5GuZ4x93h
    view full post

    January 2, 2024

    1

  • Daniel Isaza
    @danielisazamd (Twitter)

    Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission: A Secondary Analysis of the STRONG-HF Randomized Clinical Trial | Cardiology | JAMA Cardiology | JAMA Network https://t.co/IbsCHqcZVC
    view full post

    January 2, 2024

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  • Maria Hazel Cohan, DNP, AGACNP-BC, AACC
    @mcvhaze (Twitter)

    Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission https://t.co/AxVG5LFDVk
    view full post

    January 2, 2024

  • Indian Heart Association
    @theindianheart (Twitter)

    Full article open access #FOAMed : https://t.co/SZGfFEPUa5
    view full post

    December 31, 2023

    2

  • pinacol
    @pinacol (Twitter)

    【追加解析: STRONG-HF】急性心不全患者において、GDMT（RAS阻害薬、β遮断薬およびMRA）の最適な投与量に対する投与量の割合の平均値の10%の増加は、180日心不全再入院または全原因死亡の減少と関連した。90日時点のQoLはGDMTの投与量が多い患者でより改善が見られた。 #ペ読 https://t.co/NfO23lWl6x
    view full post

    December 30, 2023

    13

  • JORGE FERNANDEZ
    @drjorfer (Twitter)

    Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission: A Secondary Analysis of the STRONG-HF Randomized Clinical Trial | Cardiology | JAMA Cardiology | JAMA Network✅☑️✅☑️ https://t.co/Ry5SDsnBDA
    view full post

    December 29, 2023

  • Tom Hsiung
    @TomHsiung (Twitter)

    Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission https://t.co/4LzFKHd20u
    view full post

    December 29, 2023

  • Dr. Martha Gulati ♥️
    @DrMarthaGulati (Twitter)

    RT @JAMACardio: When patients with acute heart failure can tolerate higher doses of guideline-directed medical therapy, results suggest tha…
    view full post

    December 28, 2023

    12

  • Daniele Rodolico
    @DanieleRodolico (Twitter)

    RT @JAMACardio: When patients with acute heart failure can tolerate higher doses of guideline-directed medical therapy, results suggest tha…
    view full post

    December 28, 2023

    12

  • Audrey De Jong
    @audreydejongMD (Twitter)

    RT @dar_louis:
    view full post

    December 28, 2023

    6

  • Dr. Martha Gulati ♥️
    @DrMarthaGulati (Twitter)

    RT @gcfmd: Among patients with AHF randomly assigned to high-intensity care, achieving higher doses of HF GDMT within 2 wks after
    view full post

    December 28, 2023

    6

  • Gregg Fonarow MD
    @gcfmd (Twitter)

    RT @JAMACardio: When patients with acute heart failure can tolerate higher doses of guideline-directed medical therapy, results suggest tha…
    view full post

    December 28, 2023

    12

  • JAMA Cardiology
    @JAMACardio (Twitter)

    When patients with acute heart failure can tolerate higher doses of guideline-directed medical therapy, results suggest that all efforts should be made to rapidly uptitrate to optimal doses of the 3 and (likely) 4 pillars of HF medications. https://t.co/OR8WefrTCM
    view full post

    December 28, 2023

    37

    12

  • Dépret François
    @depret_francois (Twitter)

    RT @dar_louis:
    view full post

    December 28, 2023

    6

  • i-micro Trial
    @TrialMicro (Twitter)

    RT @dar_louis:
    view full post

    December 28, 2023

    6

  • Alexandre Mebazaa
    @AlexMebazaa (Twitter)

    RT @gcfmd: Among patients with AHF randomly assigned to high-intensity care, achieving higher doses of HF GDMT within 2 wks after
    view full post

    December 28, 2023

    6

  • Alexandre Mebazaa
    @AlexMebazaa (Twitter)

    RT @dar_louis:
    view full post

    December 28, 2023

    6

  • JorgeEdoChava75
    @QicenoJorge (Twitter)

    RT @FormigaFrancesc: Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission https://t.co/Rat9rSc0y…
    view full post

    December 28, 2023

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  • Emmanuel Dudoignon
    @EDudoignon (Twitter)

    RT @dar_louis:
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    December 28, 2023

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  • Matthieu Jabaudon
    @mj0b (Twitter)

    RT @dar_louis:
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    December 28, 2023

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  • DARMPO Hôpital Saint Louis
    @dar_louis (Twitter)


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    December 28, 2023

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  • Francesc Formiga
    @FormigaFrancesc (Twitter)

    Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission https://t.co/Rat9rSc0yS @IcyfaSemi @Medtorek @SABOURETCardio
    view full post

    December 28, 2023

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    1

  • Valva Mitralis
    @Mitrovalvology (Twitter)

    RT @gcfmd: Among patients with AHF randomly assigned to high-intensity care, achieving higher doses of HF GDMT within 2 wks after
    view full post

    December 27, 2023

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  • Ovidio García
    @ovidiogarciav (Twitter)

    RT @gcfmd: Among patients with AHF randomly assigned to high-intensity care, achieving higher doses of HF GDMT within 2 wks after
    view full post

    December 27, 2023

    6

  • Sintayehu Abebe
    @sinta_gf (Twitter)

    RT @ZHeart11768530: Optimization of Evidence-Based #HF drugs After an #AHF Admission: A 2ry Analysis of STRONG-HF Trial ✅ When pts tolera…
    view full post

    December 27, 2023

    1

  • The Heart
    @ZHeart11768530 (Twitter)

    Optimization of Evidence-Based #HF drugs After an #AHF Admission: A 2ry Analysis of STRONG-HF Trial ✅ When pts tolerate higher doses of GDMT, all efforts should be made to rapidly uptitrate to optimal doses of the 3 & (likely) 4 pillars of HF drugs https://t.co/hxYuCscWhk https://t.co/wa3TBaOGKq
    view full post

    December 27, 2023

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  • Sherif
    @Sherifdotcom (Twitter)

    RT @gcfmd: Among patients with AHF randomly assigned to high-intensity care, achieving higher doses of HF GDMT within 2 wks after
    view full post

    December 27, 2023

    6

  • Gregg Fonarow MD
    @gcfmd (Twitter)

    Among patients with AHF randomly assigned to high-intensity care, achieving higher doses of HF GDMT within 2 wks after
    view full post

    December 27, 2023

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Abstract Synopsis

  • The study analyzed how quickly and effectively patients with acute heart failure (AHF) received optimized doses of heart failure medications after hospital discharge, aiming for full doses within 2 weeks.
  • Patients who achieved higher doses of medications like RAS inhibitors and mineralocorticoid receptor antagonists generally had better outcomes, but those with lower blood pressure and more symptoms were less likely to reach optimal doses.
  • The analysis also looked at 180-day readmission or death rates and quality of life changes, emphasizing the importance of quickly reaching guideline-recommended medication doses for improving patient outcomes.]