Synopsis of Social media discussions
Discussions reflect a balanced interest and engagement with the research, with examples like mentions of structural drug similarities and long-term health risks, as well as calls for caution and further evaluation, shaped by a tone that combines scientific curiosity with health concerns.
Agreement
Moderate agreementMost discussions acknowledge the potential risks highlighted in the publication, such as the structural similarities between psychedelics and known cardiotoxins, showing a moderate consensus in support.
Interest
Moderate level of interestPosts demonstrate a moderate level of curiosity, with users referencing specific mechanisms like the 5-HT2B receptor and long-term health impacts, indicating engagement with the scientific content.
Engagement
Moderate level of engagementSeveral comments discuss the implications of the research, referencing methods, potential risks, and safety concerns, reflecting a thoughtful and involved exam of the topic.
Impact
Moderate level of impactThe discussions suggest a recognition of the study’s importance and potential influence on public health perceptions and future research directions.
Social Mentions
YouTube
2 Videos
33 Posts
1 Posts
News
1 Articles
12 Posts
Metrics
Video Views
6,638
Total Likes
400
Extended Reach
147,359
Social Features
49
Timeline: Posts about article
Top Social Media Posts
BryanRoth
We discuss the relationship between drug-induced cardiac fibrosis and the 5-HT2B receptor, and we make recommendations for evaluating the safety of microdosing psychedelics in future studies.
#psychedelics
https://t.co/quqxq0WWf8
view full post
テ"力めの犬
やはりマイクロドージングは一部の心疾患に対する罹患リスクを高めるのではないか？続報が待たれる。
LSDとシロシビンは、メチルセルジド、ペルゴリド、フェンフルラミンなど、常用するとcardiac fibrosisや心臓弁膜症のリスクを高める薬物と構造的に類似。
https://t.co/QPdne2pRg4
view full post
Prakash Masand
Though microdosing psychedelics has become increasingly popular, its long-term effects may include #cardiac #fibrosis and valvular #heart disease.There is a lot of hype around psychedelics. User beware! https://t.co/u5c7pFcf9S #nursepractitioner #mentalhealth #psychiatry
view full post
josh hardman
"Concerningly, both LSD and psilocybin share structural similarities with medications which raise the risk of cardiac fibrosis and valvulopathy when taken regularly, including methysergide, pergolide, and fenfluramine."
https://t.co/peJQerdedL
view full post
Grinspoon -- Grinspoon on Drugs
A good reminder that there's no free lunch with ANY medication!
'Microdosing psychedelics and the risk of cardiac fibrosis and valvulopathy: Comparison to known cardiotoxins'
#psychedelics
https://t.co/cAHvkdLyng
view full post
Posts referencing the article
Exploring LSD's Therapeutic Potential in Psychiatry
This video delves into the fascinating history of LSD, from its accidental discovery to its therapeutic use in psychiatry. We discuss its potential in treating depression, anxiety, and PTSD, highlighting modern perspectives on controlled psychedelic use in therapeutic settings.
April 27, 2025
6,579 views
Microdosing Psychedelics and Cardiac Health Risks
This episode explores how microdosing psychedelics supports mindfulness and emotional balance. It includes practical guidance on microdosing, spiritual dimensions of psychedelic work, and insights into fostering personal growth and self-compassion.
November 30, 2024
59 views
-
RT @Josh__Hardman: "Concerningly, both LSD and psilocybin share structural similarities with medications which raise the risk of cardiac fi…
view full postAugust 10, 2025
4
-
Heart Matters
@HeartNewsOnline (Twitter)Microdosing psychedelics and the risk of cardiac fibrosis and valvulopathy https://t.co/nzkZibdFf4
view full postMarch 5, 2025
-
@Dontfeedthef0x (Twitter)@misty_turquoise https://t.co/bfW1A40ua5
view full postSeptember 15, 2024
2
-
Kelly A. Hogan Ph.D.
@Loose_Lab_Rat (Twitter)Microdosing psychedelics and the risk of cardiac fibrosis and valvulopathy: Comparison to known cardiotoxins https://t.co/2ChV3PzRA3
view full postAugust 5, 2024
2
-
M
@missylyn19 (Twitter)@EmilioAndreazza @NTFabiano https://t.co/mNpKUdXUDn
view full postJuly 5, 2024
-
Awaken The #METAD | r/microdosing | Mush Love
@LiveInMushLove (Twitter)RT @Neurons2Nirvana: Abstract; Table; Figure; Conclusion | #Microdosing #psychedelics and the risk of #cardiac #fibrosis and #valvulopathy:…
view full postApril 27, 2024
1
-
Awaken The #METAD | r/microdosing | Mush Love
@LiveInMushLove (Twitter)Abstract; Table; Figure; Conclusion | #Microdosing #psychedelics and the risk of #cardiac #fibrosis and #valvulopathy: Comparison to known #cardiotoxins | Journal of #Psychopharmacology [Jan 2024]: https://t.co/iwiiAjlAm4 https://t.co/lHPbMUz3v7
view full postApril 16, 2024
1
-
P
@psychopharmacol (Twitter)Both LSD and psilocybin share structural similarities with medications which raise the risk of cardiac fibrosis and valvulopathy when taken regularly (methysergide, pergolide, fenfluramine, and 3,4-MDMA) https://t.co/6S9NFW4VgK https://t.co/VnWIltXgC2
view full postMarch 19, 2024
3
-
Virophagy
@virophagy (Twitter)@bioenergy_space I hope theres a workaround for this issue https://t.co/XEWPrhPnJH
view full postFebruary 2, 2024
3
-
A Punk Rock Future
@APunkRockFuture (Twitter)RT @PMasand: Though microdosing psychedelics has become increasingly popular, its long-term effects may include #cardiac #fibrosis and valv…
view full postJanuary 30, 2024
2
-
Mario Perales
@Dr_MarioPerales (Twitter)RT @PMasand: Though microdosing psychedelics has become increasingly popular, its long-term effects may include #cardiac #fibrosis and valv…
view full postJanuary 30, 2024
2
-
Prakash Masand
@PMasand (Twitter)Though microdosing psychedelics has become increasingly popular, its long-term effects may include #cardiac #fibrosis and valvular #heart disease.There is a lot of hype around psychedelics. User beware! https://t.co/u5c7pFcf9S #nursepractitioner #mentalhealth #psychiatry
view full postJanuary 30, 2024
8
2
-
テ"力めの犬
@Lotus_Solus (Twitter)やはりマイクロドージングは一部の心疾患に対する罹患リスクを高めるのではないか？続報が待たれる。 LSDとシロシビンは、メチルセルジド、ペルゴリド、フェンフルラミンなど、常用するとcardiac fibrosisや心臓弁膜症のリスクを高める薬物と構造的に類似。 https://t.co/QPdne2pRg4
view full postJanuary 26, 2024
19
-
Dr. Lelde Clemente
@leldepelde (Twitter)Reference: Rouaud et al., “Microdosing psychedelics and the risk of cardiac fibrosis and valvulopathy: Comparison to known cardiotoxins”, Journal of Psychopharmacology, 2024 /end
view full postJanuary 22, 2024
1
-
Jef Martens
@artens (Twitter)RT @Peter_Grinspoon: A good reminder that there's no free lunch with ANY medication! 'Microdosing psychedelics and the risk of cardiac fibr…
view full postJanuary 22, 2024
3
-
Alexie Vallejo Silva
@AlexieVallejo (Twitter)RT @psychopharmacol: Microdosing psychedelics (sub-threshold doses of LSD, psilocybin, or other 2–4 times a week) raise the risk of cardiac…
view full postJanuary 21, 2024
1
-
Balázs Szigeti
@psybalazs (Twitter)RT @Josh__Hardman: "Concerningly, both LSD and psilocybin share structural similarities with medications which raise the risk of cardiac fi…
view full postJanuary 21, 2024
4
-
Julien Dumesnil
@JuDuBZH (Twitter)RT @Peter_Grinspoon: A good reminder that there's no free lunch with ANY medication! 'Microdosing psychedelics and the risk of cardiac fibr…
view full postJanuary 20, 2024
3
-
eksogen
@eksogenisk (Twitter)RT @Peter_Grinspoon: A good reminder that there's no free lunch with ANY medication! 'Microdosing psychedelics and the risk of cardiac fibr…
view full postJanuary 20, 2024
3
-
Grinspoon -- Grinspoon on Drugs
@Peter_Grinspoon (Twitter)A good reminder that there's no free lunch with ANY medication! 'Microdosing psychedelics and the risk of cardiac fibrosis and valvulopathy: Comparison to known cardiotoxins' #psychedelics https://t.co/cAHvkdLyng
view full postJanuary 20, 2024
5
3
-
P
@psychopharmacol (Twitter)Microdosing psychedelics (sub-threshold doses of LSD, psilocybin, or other 2–4 times a week) raise the risk of cardiac fibrosis and valvulopathy when taken regularly. There is a relationship between cardiac fibrosis and the 5-HT2B receptor https://t.co/6S9NFW4VgK https://t.co/IoRxEJoQYb
view full postJanuary 19, 2024
1
-
Blossom
@blossomact (Twitter)This review assesses the potential long-term impact of microdosing psychedelics on cardiac health, particularly focusing on LSD and psilocybin. https://t.co/nw56foyNhS
view full postJanuary 19, 2024
4
1
-
CopperKettle
@Artyom_Yekat (Twitter)RT @zenbrainest: We discuss the relationship between drug-induced cardiac fibrosis and the 5-HT2B receptor, and we make recommendations for…
view full postJanuary 19, 2024
6
-
Jakub Schimmelpfennig
@psychedmt (Twitter)RT @zenbrainest: We discuss the relationship between drug-induced cardiac fibrosis and the 5-HT2B receptor, and we make recommendations for…
view full postJanuary 18, 2024
6
-
Joshua Rosenblat, MD, MSc, FRCPC
@JD_Rosenblat (Twitter)RT @zenbrainest: We discuss the relationship between drug-induced cardiac fibrosis and the 5-HT2B receptor, and we make recommendations for…
view full postJanuary 18, 2024
6
-
Jibran Khokhar
@DrJKhokhar (Twitter)RT @zenbrainest: We discuss the relationship between drug-induced cardiac fibrosis and the 5-HT2B receptor, and we make recommendations for…
view full postJanuary 18, 2024
6
-
Dr. Rick Barnett, PsyD
@drrickbarnett (Twitter)RT @zenbrainest: We discuss the relationship between drug-induced cardiac fibrosis and the 5-HT2B receptor, and we make recommendations for…
view full postJanuary 17, 2024
6
-
BryanRoth
@zenbrainest (Twitter)RT @zenbrainest: We discuss the relationship between drug-induced cardiac fibrosis and the 5-HT2B receptor, and we make recommendations for…
view full postJanuary 17, 2024
6
-
BryanRoth
@zenbrainest (Twitter)We discuss the relationship between drug-induced cardiac fibrosis and the 5-HT2B receptor, and we make recommendations for evaluating the safety of microdosing psychedelics in future studies. #psychedelics https://t.co/quqxq0WWf8
view full postJanuary 17, 2024
26
6
-
bernardo parrella
@berny (Twitter)RT @Josh__Hardman: "Concerningly, both LSD and psilocybin share structural similarities with medications which raise the risk of cardiac fi…
view full postJanuary 14, 2024
4
-
Jason Luoma
@jasonluoma (Twitter)RT @Josh__Hardman: "Concerningly, both LSD and psilocybin share structural similarities with medications which raise the risk of cardiac fi…
view full postJanuary 13, 2024
4
-
josh hardman
@Josh__Hardman (Twitter)"Concerningly, both LSD and psilocybin share structural similarities with medications which raise the risk of cardiac fibrosis and valvulopathy when taken regularly, including methysergide, pergolide, and fenfluramine." https://t.co/peJQerdedL
view full postJanuary 13, 2024
7
4
-
THERADELICS
@theradelics (Twitter)Microdosing psychedelics and the risk of cardiac fibrosis and valvulopathy: Comparison to known cardiotoxins https://t.co/LTQnQmDJR6 https://t.co/Liva5TX8qH
view full postJanuary 12, 2024
1
-
Hou Book | PDF
2024, doi: 10.1177/02698811231225609. Houbook v1.4.0 45 [25] Z. Postránecká, C. Vejmola, a F. Tylš, „Psychedelic therapy in the Czech Republic: A ...
view full postDecember 15, 2025
News
-
help me with this study : r/microdosing
https://journals.sagepub.com/doi/10.1177/02698811231225609. Can't find anything to disprove it, just not enough research in the area ...
view full postJune 19, 2025
Reddit
-
Psychedelics : r/valvereplacement
... general on psychedelics and heart/valve health. https://journals.sagepub.com/doi/10.1177/02698811231225609 · leoleogeebank. OP • 6mo ago.
view full postJune 10, 2025
Reddit
-
Trying to replace Adderall with a supplement stack — what's worked ...
https://journals.sagepub.com/doi/10.1177/02698811231225609. May not be the best / most rigorous research paper though. But it's a maybe and ...
view full postMay 11, 2025
Reddit
-
Psychedelics, Individuation, and the Alchemy of Well-Being : r/Jung
https://journals.sagepub.com/doi/10.1177/02698811231225609#:~:text=Concerningly%2C%20both%20LSD%20and%20psilocybin,methysergide%2C%20pergolide% ...
view full postApril 9, 2025
Reddit
-
Psychodeliki, Indywidualizacja i Alchemia Dobrego Samopoczucia ...
https://journals.sagepub.com/doi/10.1177/02698811231225609#:~:text=Concerningly%2C%20both%20LSD%20and%20psilocybin,methysergide%2C%20pergolide% ...
view full postApril 9, 2025
Reddit
-
"If you were designing the ultimate nootropics lineup for 2025, what ...
... something with significant 5HT2B agonism https://journals.sagepub.com/doi/10.1177/02698811231225609 · Traditional_Gas8325. • 1y ago.
view full postDecember 23, 2024
Reddit
-
Is there a law of diminishing return for taking shrooms and reaping ...
... 10.1177/02698811231225609 and others. The risk is low and I'd expect very low doses a few days on and a few days off would limit it further ...
view full postOctober 28, 2024
Reddit
-
Tired of SSRI's : r/COpsychonauts
... microdose every day without breaks so I do see a risk there. https://journals.sagepub.com/doi/10.1177/02698811231225609 · Hourglass7200. • 2y ...
view full postMay 7, 2024
Reddit
-
What is the worst case scenario? : r/Psychedelics
... .com/doi/full/10.1177/02698811231225609 · https://chacruna.net/why-chronic-microdosing-might-break-your-heart/ · Bad_Packet. • 2y ago.
view full postMay 4, 2024
Reddit
-
Side effect of mushrooms (heart health or subconscious thoughts ...
https://journals.sagepub.com/doi/10.1177/02698811231225609. Highly likely that prolonged use of psychedelics like LSD or Psilocybin will ...
view full postApril 1, 2024
Reddit
-
Jakie narkotyki są bezpieczne podczas przyjmowania Zoloftu? : r/zoloft
Czasami ryzyko jest warte nagrody, czasami nie. https://journals.sagepub.com/doi/10.1177/02698811231225609#:~:text=One%20recent%20review% ...
view full postMarch 23, 2024
Reddit
-
What drugs are safe on Zoloft? : r/zoloft
https://journals.sagepub.com/doi/10.1177/02698811231225609#:~:text=One%20recent%20review%20concluded%20that,et%20al.%2C%202023). More replies.
view full postMarch 23, 2024
Reddit
-
Hjärtklaffsjukdomar och hjärtfibros av mikrodosering? Långvarig ...
... av mikrodosering allvarligt när dess popularitet ökar. https://journals.sagepub.com/doi/10.1177/02698811231225609".
view full postFebruary 12, 2024
Instagram
Abstract Synopsis
- Microdosing psychedelics like LSD and psilocybin involves taking small doses regularly over weeks or months, but their long-term impact on heart health is not well understood.
- Since these drugs share structural similarities with known heart-toxic medications such as methysergide and fenfluramine, there is concern they could increase the risk of cardiac fibrosis and valvulopathy with long-term use.
- The review emphasizes the importance of studying the role of the 5HT2B receptor in drug-induced heart damage and calls for careful evaluation of the safety of microdosing psychedelics in future research.]
np
@7witz37 (Twitter)