Discussions reflect a balanced interest and engagement with the research, with examples like mentions of structural drug similarities and long-term health risks, as well as calls for caution and further evaluation, shaped by a tone that combines scientific curiosity with health concerns.
AgreementModerate agreement
Most discussions acknowledge the potential risks highlighted in the publication, such as the structural similarities between psychedelics and known cardiotoxins, showing a moderate consensus in support.
InterestModerate interest
Posts demonstrate a moderate level of curiosity, with users referencing specific mechanisms like the 5-HT2B receptor and long-term health impacts, indicating engagement with the scientific content.
EngagementModerate engagement
Several comments discuss the implications of the research, referencing methods, potential risks, and safety concerns, reflecting a thoughtful and involved exam of the topic.
ImpactModerate impact
The discussions suggest a recognition of the study’s importance and potential influence on public health perceptions and future research directions.
Abstract in brief
Microdosing psychedelics like LSD and psilocybin involves taking small doses regularly over weeks or months, but their long-term impact on heart health is not well understood.
Since these drugs share structural similarities with known heart-toxic medications such as methysergide and fenfluramine, there is concern they could increase the risk of cardiac fibrosis and valvulopathy with long-term use.
The review emphasizes the importance of studying the role of the 5HT2B receptor in drug-induced heart damage and calls for careful evaluation of the safety of microdosing psychedelics in future research.]
We discuss the relationship between drug-induced cardiac fibrosis and the 5-HT2B receptor, and we make recommendations for evaluating the safety of microdosing psychedelics in future studies.
#psychedelics
https://t.co/quqxq0WWf8
Jan 17, 2024 · 26 likes · 6 shares · 17,120 followersView post →
Jan 26, 2024 · 19 likes · 1,846 followersView post →
PM
Prakash Masand
@PMasand · X
Though microdosing psychedelics has become increasingly popular, its long-term effects may include #cardiac #fibrosis and valvular #heart disease.There is a lot of hype around psychedelics. User beware! https://t.co/u5c7pFcf9S #nursepractitioner #mentalhealth #psychiatry
Jan 30, 2024 · 8 likes · 2 shares · 474 followersView post →
JH
josh hardman
@Josh__Hardman · X
"Concerningly, both LSD and psilocybin share structural similarities with medications which raise the risk of cardiac fibrosis and valvulopathy when taken regularly, including methysergide, pergolide, and fenfluramine."
https://t.co/peJQerdedL
Jan 13, 2024 · 7 likes · 4 shares · 3,709 followersView post →
GD
Grinspoon -- Grinspoon on Drugs
@Peter_Grinspoon · X
A good reminder that there's no free lunch with ANY medication!
'Microdosing psychedelics and the risk of cardiac fibrosis and valvulopathy: Comparison to known cardiotoxins'
#psychedelics
https://t.co/cAHvkdLyng
Jan 20, 2024 · 5 likes · 3 shares · 35,354 followersView post →
B
Blossom
@blossomact · X
This review assesses the potential long-term impact of microdosing psychedelics on cardiac health, particularly focusing on LSD and psilocybin. https://t.co/nw56foyNhS
Jan 19, 2024 · 4 likes · 1 share · 3,349 followersView post →
This video delves into the fascinating history of LSD, from its accidental discovery to its therapeutic use in psychiatry. We discuss its potential in treating depression, anxiety, and PTSD, highlighting modern…
This episode explores how microdosing psychedelics supports mindfulness and emotional balance. It includes practical guidance on microdosing, spiritual dimensions of psychedelic work, and insights into fostering…
Abstract; Table; Figure; Conclusion | #Microdosing #psychedelics and the risk of #cardiac #fibrosis and #valvulopathy: Comparison to known #cardiotoxins | Journal of #Psychopharmacology [Jan 2024]: https://t.co/iwiiAjlAm4 https://t.co/lHPbMUz3v7
Both LSD and psilocybin share structural similarities with medications which raise the risk of cardiac fibrosis and valvulopathy when taken regularly (methysergide, pergolide, fenfluramine, and 3,4-MDMA) https://t.co/6S9NFW4VgK https://t.co/VnWIltXgC2
Though microdosing psychedelics has become increasingly popular, its long-term effects may include #cardiac #fibrosis and valvular #heart disease.There is a lot of hype around psychedelics. User beware! https://t.co/u5c7pFcf9S #nursepractitioner #mentalhealth #psychiatry
Jan 30, 2024 · 8 likes · 2 shares · 474 followersView post →
Jan 26, 2024 · 19 likes · 1,846 followersView post →
DC
Dr. Lelde Clemente
@leldepelde · X
Reference: Rouaud et al., “Microdosing psychedelics and the risk of cardiac fibrosis and valvulopathy: Comparison to known cardiotoxins”, Journal of Psychopharmacology, 2024
/end
Jan 22, 2024 · 1 like · 2,806 followersView post →
JM
Jef Martens
@artens · X
RT @Peter_Grinspoon: A good reminder that there's no free lunch with ANY medication!
'Microdosing psychedelics and the risk of cardiac fibr…
Jan 22, 2024 · 3 shares · 464 followersView post →
AS
Alexie Vallejo Silva
@AlexieVallejo · X
RT @psychopharmacol: Microdosing psychedelics (sub-threshold doses of LSD, psilocybin, or other 2–4 times a week) raise the risk of cardiac…
RT @Josh__Hardman: "Concerningly, both LSD and psilocybin share structural similarities with medications which raise the risk of cardiac fi…
Jan 21, 2024 · 4 shares · 3,287 followersView post →
JD
Julien Dumesnil
@JuDuBZH · X
RT @Peter_Grinspoon: A good reminder that there's no free lunch with ANY medication!
'Microdosing psychedelics and the risk of cardiac fibr…
Jan 20, 2024 · 3 shares · 1,617 followersView post →
E
eksogen
@eksogenisk · X
RT @Peter_Grinspoon: A good reminder that there's no free lunch with ANY medication!
'Microdosing psychedelics and the risk of cardiac fibr…
Jan 20, 2024 · 3 shares · 1,950 followersView post →
GD
Grinspoon -- Grinspoon on Drugs
@Peter_Grinspoon · X
A good reminder that there's no free lunch with ANY medication!
'Microdosing psychedelics and the risk of cardiac fibrosis and valvulopathy: Comparison to known cardiotoxins'
#psychedelics
https://t.co/cAHvkdLyng
Jan 20, 2024 · 5 likes · 3 shares · 35,354 followersView post →
P
P
@psychopharmacol · X
Microdosing psychedelics (sub-threshold doses of LSD, psilocybin, or other 2–4 times a week) raise the risk of cardiac fibrosis and valvulopathy when taken regularly. There is a relationship between cardiac fibrosis and the 5-HT2B receptor https://t.co/6S9NFW4VgK https://t.co/IoRxEJoQYb
This review assesses the potential long-term impact of microdosing psychedelics on cardiac health, particularly focusing on LSD and psilocybin. https://t.co/nw56foyNhS
Jan 19, 2024 · 4 likes · 1 share · 3,349 followersView post →
C
CopperKettle
@Artyom_Yekat · X
RT @zenbrainest: We discuss the relationship between drug-induced cardiac fibrosis and the 5-HT2B receptor, and we make recommendations for…
Jan 19, 2024 · 6 shares · 385 followersView post →
JS
Jakub Schimmelpfennig
@psychedmt · X
RT @zenbrainest: We discuss the relationship between drug-induced cardiac fibrosis and the 5-HT2B receptor, and we make recommendations for…
Jan 18, 2024 · 6 shares · 409 followersView post →
JF
Joshua Rosenblat, MD, MSc, FRCPC
@JD_Rosenblat · X
RT @zenbrainest: We discuss the relationship between drug-induced cardiac fibrosis and the 5-HT2B receptor, and we make recommendations for…
Jan 18, 2024 · 6 shares · 3,347 followersView post →
JK
Jibran Khokhar
@DrJKhokhar · X
RT @zenbrainest: We discuss the relationship between drug-induced cardiac fibrosis and the 5-HT2B receptor, and we make recommendations for…
Jan 18, 2024 · 6 shares · 10,861 followersView post →
DP
Dr. Rick Barnett, PsyD
@drrickbarnett · X
RT @zenbrainest: We discuss the relationship between drug-induced cardiac fibrosis and the 5-HT2B receptor, and we make recommendations for…
Jan 17, 2024 · 6 shares · 17,587 followersView post →
B
BryanRoth
@zenbrainest · X
RT @zenbrainest: We discuss the relationship between drug-induced cardiac fibrosis and the 5-HT2B receptor, and we make recommendations for…
Jan 17, 2024 · 6 shares · 17,120 followersView post →
B
BryanRoth
@zenbrainest · X
We discuss the relationship between drug-induced cardiac fibrosis and the 5-HT2B receptor, and we make recommendations for evaluating the safety of microdosing psychedelics in future studies.
#psychedelics
https://t.co/quqxq0WWf8
Jan 17, 2024 · 26 likes · 6 shares · 17,120 followersView post →
BP
bernardo parrella
@berny · X
RT @Josh__Hardman: "Concerningly, both LSD and psilocybin share structural similarities with medications which raise the risk of cardiac fi…
Jan 14, 2024 · 4 shares · 750 followersView post →
JL
Jason Luoma
@jasonluoma · X
RT @Josh__Hardman: "Concerningly, both LSD and psilocybin share structural similarities with medications which raise the risk of cardiac fi…
Jan 13, 2024 · 4 shares · 2,007 followersView post →
JH
josh hardman
@Josh__Hardman · X
"Concerningly, both LSD and psilocybin share structural similarities with medications which raise the risk of cardiac fibrosis and valvulopathy when taken regularly, including methysergide, pergolide, and fenfluramine."
https://t.co/peJQerdedL
Jan 13, 2024 · 7 likes · 4 shares · 3,709 followersView post →
T
THERADELICS
@theradelics · X
Microdosing psychedelics and the risk of cardiac fibrosis and valvulopathy: Comparison to known cardiotoxins https://t.co/LTQnQmDJR6 https://t.co/Liva5TX8qH
Jan 12, 2024 · 1 like · 3,390 followersView post →
N
Hou Book | PDF
News
2024, doi: 10.1177/02698811231225609. Houbook v1.4.0 45 [25] Z. Postránecká, C. Vejmola, a F. Tylš, „Psychedelic therapy in the Czech Republic: A ...
B
テ力
PM
JH
GD
B
N
HM
DX
KD
M
AL
P
V
AF
MP
DC
JM
AS
BS
JD
E
C
JS
JF
JK
DP
BP
JL
T