Dynamic and selective engrams emerge with memory consolidation.

Douglas Feitosa Tomé, Ying Zhang, Tomomi Aida, Olivia Mosto, Yifeng Lu, Mandy Chen, Sadra Sadeh, Dheeraj S Roy, Claudia Clopath

March 2024 Nat Neurosci

Synopsis of Social media discussions

The discussions reflect genuine interest and support, with comments emphasizing the importance of memory mechanisms, as seen in phrases like 'Neurocientistas mostram' and hashtags focusing on science and memory, which demonstrate appreciation and recognition of the study's scientific contribution, though limited to general understanding rather than detailed debate.

A
Agreement
 Moderate agreement

Most discussions highlight support for the importance of the research, recognizing how memory engrams evolve during consolidation, evidenced by phrases like 'neurocientistas mostram' and references to structural brain processes.

I
Interest
 High level of interest

Participants show high interest, actively sharing articles, using hashtags like #Memória and #science, and mentioning research techniques such as calcium imaging, indicating engagement with the scientific content.

E
Engagement
 Moderate level of engagement

The discussions include specific references to the study's findings, methods, and implications, though mostly in a summary or promotional tone rather than deep technical analysis.

I
Impact
 Moderate level of impact

The emphasis on the neuroscience findings and their relevance suggests users believe the research could influence understanding of memory processes, but the overall tone remains exploratory rather than asserting groundbreaking impact.

Social Mentions

YouTube

3 Videos

Facebook

2 Posts

Twitter

28 Posts

Blogs

3 Articles

News

21 Articles

Metrics

Video Views

77

Total Likes

59

Extended Reach

325,363

Social Features

57

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

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February 20, 2024

14 views

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    RT @leafs_s: Nature Neuroscience Dynamic and selective engrams emerge with memory consolidation https://t.co/t74OTzoFaM
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    RT @leafs_s: Nature Neuroscience Dynamic and selective engrams emerge with memory consolidation https://t.co/t74OTzoFaM
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Abstract Synopsis

  • Memory engrams, which are groups of neurons involved in recalling experiences, start off as unselective but become more specific over time through a process involving inhibitory neural activity.
  • The study used both computational models and experiments with mice to show that as memories consolidate, neurons are dynamically added or removed from engrams, and inhibitory plasticity (changes in inhibitory synapses) plays a key role in making these memories more selective.
  • Techniques like calcium imaging, optogenetics, and chemogenetics confirmed that the evolution of engram composition and activity is essential for the development of precise and selective memories during the consolidation process.]