NEJM Evid July 2023 PMID 38320162

Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve.

Tracy Y Wang, Lars G Svensson, Jun Wen, Andrew Vekstein, Marc Gerdisch, Vijay U Rao, Michael Moront, Doug Johnston, Renato D Lopes, Alma Chavez, Marc Ruel, Eugene H Blackstone, Richard C Becker, Vinod Thourani, John Puskas

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Mentions

179
Peak: 128 in May 2023
across 6 sources since May 2023

Extended reach

484,157
potential audience

Total likes

394

Video views

1,080

Mentions per month

May 2023 – Jun 2025

Where it's discussed

  • X / Twitter155 posts
  • News19 articles
  • YouTube2 videos
  • Facebook1 posts
  • LinkedIn1 posts
  • Reddit1 posts

AI synopsis

What people are saying

Most discussions emphasize the trial's negative outcomes for apixaban, with phrases like 'prematurely stopped' and 'still a No Go' illustrating strong interpretations of its ineffectiveness; words like 'important work' and 'further evidence' reflect recognition of the study's high relevance and influence on clinical recommendations.

AgreementStrong disagreement

The majority of posts strongly support the conclusion that apixaban is ineffective and potentially harmful for patients with mechanical aortic valves, emphasizing the trial's findings and the need to rely on warfarin.

InterestHigh interest

These discussions demonstrate high interest due to the serious implications of the trial results, highlighting the importance of anticoagulant choices for patients with mechanical valves.

EngagementModerate engagement

Users actively analyze the research, referencing the trial, its premature termination, and broader implications, indicating moderate deep engagement.

ImpactHigh impact

The posts underscore a significant impact on clinical practice, with many highlighting the trial's influence on treatment guidelines and the ongoing debate about DOACs in this context.

Abstract in brief

  • Vitamin K antagonists like warfarin are currently the approved oral anticoagulants for preventing complications in patients with mechanical heart valves, but the efficacy of apixaban in this context was unknown.
  • In a trial comparing apixaban to warfarin for patients with On-X mechanical aortic valves, there were significantly more thromboembolic events in the apixaban group, leading to the study being halted after enrolling 863 participants.
  • The results showed that apixaban was less effective than warfarin, failing to meet the criteria for noninferiority in preventing valve thrombosis, and had comparable but slightly lower major bleeding rates.

Top posts

Most liked on X and Bluesky
Felipe Díez del Hoyo
@Felipediezhoyo · X

#ACOD de nuevo, en este caso #apixabán

May 16, 2023 · 123 likes · 34 shares · 23,996 followers View post →
Cole Smith, Pharm.D, BCPS
@iamcrsmith · X

Gonna start a monthly tweet of: "Studies released this month that you need to read" - Apixaban v Warfarin for Mech Aortic Valve (https://t.co/dBpMgD6ZXG) - Hep C Updated Guidance (https://t.co/PmG8IUJzpr) - Early v Later Anticoag for Stroke w Afib (https://t.co/NtwrrUNrcG)

May 27, 2023 · 60 likes · 7 shares · 692 followers View post →
Ariane V. Scarlatelli Macedo
@md_arianemacedo · X

No room for using DOACs in patients with mechanical aortic valves! Congrats @TYWangMD, @RenatoDLopes1, and all authors for this important piece! Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | NEJM Evidence https://t.co/ouqI6gqmMe

May 7, 2023 · 39 likes · 14 shares · 1,680 followers View post →
NEJM Evidence
@NEJMEvidence · X

Original Article: “Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve,” by @JHAlexanderMD, MHS, et al. https://t.co/XEcOJiGb9m #CardioTwitter #Afib

May 27, 2023 · 27 likes · 9 shares · 30,999 followers View post →
SCCM Clinical Pharmacy and Pharmacology Section
@SCCM_CPP · X

Is apixaban non-inferior to warfarin in patients with On-X mechanical aortic valves? Check out this infographic from #SCCMJC to learn more about the PROACT-Xa trial published in @NEJMEvidence! #PharmICU #SCCM https://t.co/yM7FCFgcG5 https://t.co/QDYpHoUKNV

Aug 28, 2024 · 23 likes · 6 shares · 3,443 followers View post →
Kam Ghadimi MD
@KamGhadimiMD · X

Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | ⁦@NEJMEvidence⁩ | ⁦@JHAlexanderMD⁩ ⁦@AndrewVekstein⁩ ⁦@IbrahimSultanMD⁩ et al. https://t.co/NqIzQZdyAl

May 27, 2023 · 22 likes · 5 shares · 1,382 followers View post →

All mentions

Limited Use of DOACs in Mechanical Heart Valve Patients

Ref httpsevidencenejmorgdoi101056EVIDoa2300067 Join DOBBS and take part in our Journal Club httpsdobbsmyosr. The study compares apixaban and warfarin in patients with On-X mechanical aortic valves, showing apixaban's…

DOBBS · Jun 11, 2023 576 views
Tom Hsiung
@TomHsiung · X

Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | NEJM Evidence https://t.co/r8TFkYSG2d

Jun 17, 2025 · 467 followers View post →
Critical Care Pharmacists
@CCPharmacists · X

RT @SCCM_CPP: Is apixaban non-inferior to warfarin in patients with On-X mechanical aortic valves? Check out this infographic from #SCCMJC…

Aug 28, 2024 · 6 shares · 4,495 followers View post →
SCCM Clinical Pharmacy and Pharmacology Section
@SCCM_CPP · X

Is apixaban non-inferior to warfarin in patients with On-X mechanical aortic valves? Check out this infographic from #SCCMJC to learn more about the PROACT-Xa trial published in @NEJMEvidence! #PharmICU #SCCM https://t.co/yM7FCFgcG5 https://t.co/QDYpHoUKNV

Aug 28, 2024 · 23 likes · 6 shares · 3,443 followers View post →
Critical Care Pharmacists
@CCPharmacists · X

RT @SCCM_CPP: @SCCM @uc_health @jama @bswhealth @NEJM #SCCMJC #PharmICU Presenter 3: Priya Patel, PharmD @priya_patel98 PGY2 CC @Methodist…

Aug 15, 2024 · 1 share · 4,495 followers View post →
SCCM Clinical Pharmacy and Pharmacology Section
@SCCM_CPP · X

@SCCM @uc_health @jama @bswhealth @NEJM #SCCMJC #PharmICU Presenter 3: Priya Patel, PharmD @priya_patel98 PGY2 CC @MethodistHosp will discuss Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve. @NEJM https://t.co/nrN4x8gAhf

Aug 15, 2024 · 2 likes · 1 share · 3,443 followers View post →
SCCM Clinical Pharmacy and Pharmacology Section
@SCCM_CPP · X

@SCCM @uc_health @jama @bswhealth @NEJM #SCCMJC #PharmICU Presenter 3: Priya Patel, PharmD (@priya_patel98) PGY2 CC @MethodistHosp will discuss Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve. @NEJM https://t.co/nrN4x8gAhf

Aug 9, 2024 · 3,443 followers View post →
Clara Arenós
@aremoncl · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

Jul 2, 2024 · 34 shares · 202 followers View post →
Arvind Canchi (Conjeevaram)
@arvindcanchi · X

Warfarin Vs Apixaban

Jun 28, 2024 · 3 likes · 10,955 followers View post →
Valva Mitralis
@Mitrovalvology · X

RT @MayoClinicCVS: Apixaban or warfarin in patients w/an On-X mechanical aortic valve? Experts including A. Pochettino, MD weigh in and sha…

Feb 9, 2024 · 2 shares · 4,135 followers View post →
John P Erwin III MD MBA MACC (#BigPoppy )
@HeartOTXHeartMD · X

RT @MayoClinicCVS: Apixaban or warfarin in patients w/an On-X mechanical aortic valve? Experts including A. Pochettino, MD weigh in and sha…

Feb 9, 2024 · 2 shares · 39,879 followers View post →
Mayo Clinic Cardiac Surgery
@MayoClinicCVS · X

Apixaban or warfarin in patients w/an On-X mechanical aortic valve? Experts including A. Pochettino, MD weigh in and share their results in this #NEJM Evidence article. https://t.co/4sg0ID7IFC

Feb 9, 2024 · 5 likes · 2 shares · 5,207 followers View post →
Robert Zhang MD
@robertshiuzhang · X

Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | NEJM Evidence https://t.co/Qd9DbfQ1me

Jul 19, 2023 · 2 likes · 475 followers View post →
Adi Elias MD MPH
@Adielias5 · X

RT @NEJMEvidence: ICYMI Original Article: “Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve,” by @TYWangMD et al. http…

Jul 12, 2023 · 4 shares · 18 followers View post →
Lars Svensson
@LarsSvenssonMD · X

RT @NEJMEvidence: ICYMI Original Article: “Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve,” by @TYWangMD et al. http…

Jul 11, 2023 · 4 shares · 5,713 followers View post →
Cleveland Clinic Heart, Vascular & Thoracic
@CleClinicHVTI · X

RT @NEJMEvidence: ICYMI Original Article: “Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve,” by @TYWangMD et al. http…

Jul 11, 2023 · 4 shares · 8,561 followers View post →
Suraj Parajuli
@ParrajuliSuraj · X

RT @NEJMEvidence: ICYMI Original Article: “Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve,” by @TYWangMD et al. http…

Jul 11, 2023 · 4 shares · 20 followers View post →
NEJM Evidence
@NEJMEvidence · X

ICYMI Original Article: “Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve,” by @TYWangMD et al. https://t.co/XEcOJiGb9m #CardioTwitter #Afib #ClinicalTrials @DCRInews @JHAlexanderMD @LarsSvenssonMD @CleClinicHVTI @ClevelandClinic @MyFranciscan

Jul 8, 2023 · 7 likes · 4 shares · 30,999 followers View post →
Sylvia Ou
@sylviaou7 · X

RT @AnticoagPharmD:

Jun 24, 2023 · 93 shares · 36 followers View post →
Chun-Ka Wong
@ChunKaWong · X

The highly anticipated PROACT-Xa trial comparing Apixaban vs Warfarin in patients who received newer generation On-X mechanical heart valve was prematurely terminated. Same fate as RE-ALIGN trial (Dabigatran vs Warfarin in mechanical heart valves). https://t.co/P67N9Mk6hb

Jun 23, 2023 · 3 likes · 351 followers View post →
Malaysian Medicine
@MyMedicalRsrc · X

DOACs for Mechanical Heart Valves : Still a No Go https://t.co/aghRRwK73Y

Jun 10, 2023 · 2,228 followers View post →
Santiago Montesinos
@MontesinosSanti · X

RT @sedar_es: #CardioToVascSEDAR

Jun 8, 2023 · 2 shares · 3,079 followers View post →
Milad Matta
@miladmattaMD · X

RT @ccfvascmed: https://t.co/XovyMaWT4e

Jun 7, 2023 · 1 share · 442 followers View post →
Cleveland Clinic Vascular Medicine
@ccfvascmed · X

https://t.co/XovyMaWT4e

Jun 7, 2023 · 2 likes · 1 share · 525 followers View post →
Jun Kim
@mdjunkim · X

Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | NEJM Evidence #Epeeps ⁦@DrChaEP⁩ https://t.co/ytdEN8S5Lg

Jun 6, 2023 · 1 like · 438 followers View post →
Jamil Mattar Valente
@JamilValente · X

The correct answer is warfarin + aspirin. See PROACT Xa trial, published recently. DOI: 10.1056/EVIDoa2300067

Jun 4, 2023 · 18 followers View post →
Lucía Gallego Ligorit
@LGallegoLigorit · X

RT @sedar_es: #CardioToVascSEDAR

Jun 3, 2023 · 2 shares · 515 followers View post →
SEDAR
@sedar_es · X

#CardioToVascSEDAR

Jun 3, 2023 · 5 likes · 2 shares · 19,819 followers View post →
Orlando Henriquez, MD
@OrlanditoCardio · X

RT @KamGhadimiMD: Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | ⁦@NEJMEvidence⁩ | ⁦@JHAlexanderMD⁩ ⁦@AndrewVekste…

May 28, 2023 · 5 shares · 275 followers View post →
Alessandro
@Alessan7681 · X

RT @KamGhadimiMD: Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | ⁦@NEJMEvidence⁩ | ⁦@JHAlexanderMD⁩ ⁦@AndrewVekste…

May 28, 2023 · 5 shares · 78 followers View post →
J.F.García-Rodríguez
@jfgarciartroito · X

RT @NEJMEvidence: Original Article: “Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve,” by @JHAlexanderMD, MHS, et al.…

May 28, 2023 · 9 shares · 100 followers View post →
Latchumanadhas K
@latchumanadhas · X

RT @KamGhadimiMD: Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | ⁦@NEJMEvidence⁩ | ⁦@JHAlexanderMD⁩ ⁦@AndrewVekste…

May 28, 2023 · 5 shares · 4,361 followers View post →
Rohit Kumar Ojha
@Cofounder0911 · X

RT @NEJMEvidence: Original Article: “Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve,” by @JHAlexanderMD, MHS, et al.…

May 28, 2023 · 9 shares · 114 followers View post →
Oscar Geraldino
@oscargeraldino · X

RT @NEJMEvidence: Original Article: “Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve,” by @JHAlexanderMD, MHS, et al.…

May 27, 2023 · 9 shares · 395 followers View post →
HUGO COLOMBO MD
@HCOLOMBO1958 · X

RT @NEJMEvidence: Original Article: “Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve,” by @JHAlexanderMD, MHS, et al.…

May 27, 2023 · 9 shares · 1,121 followers View post →
Khalid Minhas, MD FACC
@minhaskh · X

RT @KamGhadimiMD: Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | ⁦@NEJMEvidence⁩ | ⁦@JHAlexanderMD⁩ ⁦@AndrewVekste…

May 27, 2023 · 5 shares · 11,362 followers View post →
Kam Ghadimi MD
@KamGhadimiMD · X

Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | ⁦@NEJMEvidence⁩ | ⁦@JHAlexanderMD⁩ ⁦@AndrewVekstein⁩ ⁦@IbrahimSultanMD⁩ et al. https://t.co/NqIzQZdyAl

May 27, 2023 · 22 likes · 5 shares · 1,382 followers View post →
Jerrold Levy, MD
@JerroldLevy · X

RT @NEJMEvidence: Original Article: “Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve,” by @JHAlexanderMD, MHS, et al.…

May 27, 2023 · 9 shares · 2,476 followers View post →
Cole Smith, Pharm.D, BCPS
@iamcrsmith · X

Gonna start a monthly tweet of: "Studies released this month that you need to read" - Apixaban v Warfarin for Mech Aortic Valve (https://t.co/dBpMgD6ZXG) - Hep C Updated Guidance (https://t.co/PmG8IUJzpr) - Early v Later Anticoag for Stroke w Afib (https://t.co/NtwrrUNrcG)

May 27, 2023 · 60 likes · 7 shares · 692 followers View post →
Mario Alamilla-Sánchez
@MarioAlamilla · X

RT @NEJMEvidence: Original Article: “Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve,” by @JHAlexanderMD, MHS, et al.…

May 27, 2023 · 9 shares · 1,019 followers View post →
mas242728
@mas242728 · X

RT @NEJMEvidence: Original Article: “Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve,” by @JHAlexanderMD, MHS, et al.…

May 27, 2023 · 9 shares · 127 followers View post →
vnuttk.med
@vnuttk · X

RT @NEJMEvidence: Original Article: “Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve,” by @JHAlexanderMD, MHS, et al.…

May 27, 2023 · 9 shares · 19 followers View post →
NEJM Evidence
@NEJMEvidence · X

Original Article: “Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve,” by @JHAlexanderMD, MHS, et al. https://t.co/XEcOJiGb9m #CardioTwitter #Afib

May 27, 2023 · 27 likes · 9 shares · 30,999 followers View post →
Paulina Feola
@paulyhcm · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 20, 2023 · 34 shares · 641 followers View post →
AZUCENA PAJARES
@AZUCENAPAJARES · X

Apixaban or Warfarin in Patients With an On-X Mechanical Aortic Valve. The trial was prematurely stopped owing to excess thromboembolic events in the apixaban group.

May 20, 2023 · 3 likes · 447 followers View post →
Igor Morr
@igormorr · X

RT @CardioBornan: DOAC y Válvula mecánica

May 18, 2023 · 15 shares · 3,927 followers View post →
AlbanLanderos
@AlbanJavier4 · X

RT @Tomas_MA_Cardio: Apixaban vs Warfarina en prótesis aorticas mecánicas. Nuevo fracaso para NOACs. ⬆️Tromboembolismo. ☑️Warfarina en casi…

May 18, 2023 · 36 shares · 29 followers View post →
Cristian Chapoñan Bances
@CristianChapoB · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 18, 2023 · 34 shares · 46 followers View post →
Carola Maraboto
@CarolaMaraboto · X

RT @Tomas_MA_Cardio: Apixaban vs Warfarina en prótesis aorticas mecánicas. Nuevo fracaso para NOACs. ⬆️Tromboembolismo. ☑️Warfarina en casi…

May 17, 2023 · 36 shares · 248 followers View post →
Daniel Rebolledo, PhD, MD
@DanielReb1989 · X

RT @Tomas_MA_Cardio: Apixaban vs Warfarina en prótesis aorticas mecánicas. Nuevo fracaso para NOACs. ⬆️Tromboembolismo. ☑️Warfarina en casi…

May 17, 2023 · 36 shares · 95 followers View post →
The Viking Turtle
@TheVikingTurtle · X

RT @Tomas_MA_Cardio: Apixaban vs Warfarina en prótesis aorticas mecánicas. Nuevo fracaso para NOACs. ⬆️Tromboembolismo. ☑️Warfarina en casi…

May 17, 2023 · 36 shares · 145 followers View post →
Kamol
@KamolMU · X

RT @Tomas_MA_Cardio: Apixaban vs Warfarina en prótesis aorticas mecánicas. Nuevo fracaso para NOACs. ⬆️Tromboembolismo. ☑️Warfarina en casi…

May 17, 2023 · 36 shares · 100 followers View post →
jomincp
@jomincp · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 17, 2023 · 34 shares · 11 followers View post →
Liz
@Teffa_VL · X

RT @Tomas_MA_Cardio: Apixaban vs Warfarina en prótesis aorticas mecánicas. Nuevo fracaso para NOACs. ⬆️Tromboembolismo. ☑️Warfarina en casi…

May 17, 2023 · 36 shares · 54 followers View post →
Alfonso Canas
@canasalf · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 17, 2023 · 34 shares · 346 followers View post →
Alan Méndez T
@alan_mndez · X

RT @CardioBornan: DOAC y Válvula mecánica

May 16, 2023 · 15 shares · 44 followers View post →
felipeignaciomj
@felipeignaciomj · X

RT @Tomas_MA_Cardio: Apixaban vs Warfarina en prótesis aorticas mecánicas. Nuevo fracaso para NOACs. ⬆️Tromboembolismo. ☑️Warfarina en casi…

May 16, 2023 · 36 shares · 120 followers View post →
EOLO MORANDI JR.
@eolojr · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 16, 2023 · 34 shares · 543 followers View post →
Orlando Castaño
@orlando182 · X

RT @Tomas_MA_Cardio: Apixaban vs Warfarina en prótesis aorticas mecánicas. Nuevo fracaso para NOACs. ⬆️Tromboembolismo. ☑️Warfarina en casi…

May 16, 2023 · 36 shares · 263 followers View post →
Bryan Quintanilla
@Brysten23 · X

RT @Tomas_MA_Cardio: Apixaban vs Warfarina en prótesis aorticas mecánicas. Nuevo fracaso para NOACs. ⬆️Tromboembolismo. ☑️Warfarina en casi…

May 16, 2023 · 36 shares · 276 followers View post →
CHICHITO CHACO
@chichodisanto · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 16, 2023 · 34 shares · 6,689 followers View post →
Nicolas D. Santoyo S
@NicolasSantoyoS · X

RT @Tomas_MA_Cardio: Apixaban vs Warfarina en prótesis aorticas mecánicas. Nuevo fracaso para NOACs. ⬆️Tromboembolismo. ☑️Warfarina en casi…

May 16, 2023 · 36 shares · 549 followers View post →
Carmen Quiñonez
@Carmenky09 · X

RT @Tomas_MA_Cardio: Apixaban vs Warfarina en prótesis aorticas mecánicas. Nuevo fracaso para NOACs. ⬆️Tromboembolismo. ☑️Warfarina en casi…

May 16, 2023 · 36 shares · 90 followers View post →
Juan Ángel
@Jangel9 · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 16, 2023 · 34 shares · 680 followers View post →
Medicina Interna HCSBA
@MHcsba · X

RT @Tomas_MA_Cardio: Apixaban vs Warfarina en prótesis aorticas mecánicas. Nuevo fracaso para NOACs. ⬆️Tromboembolismo. ☑️Warfarina en casi…

May 16, 2023 · 36 shares · 8,969 followers View post →
JuanManuel
@JuanmaTorrado · X

RT @Tomas_MA_Cardio: Apixaban vs Warfarina en prótesis aorticas mecánicas. Nuevo fracaso para NOACs. ⬆️Tromboembolismo. ☑️Warfarina en casi…

May 16, 2023 · 36 shares · 564 followers View post →
Miguel Azañedo V
@MikeMD2486 · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 16, 2023 · 34 shares · 404 followers View post →
David GGlez
@DavidGGlezFarm · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 16, 2023 · 34 shares · 139 followers View post →
Stefano Fabbiani
@fefofabbiani · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 16, 2023 · 34 shares · 589 followers View post →
Sebastián Camus Ríos
@rios_camus · X

RT @Tomas_MA_Cardio: Apixaban vs Warfarina en prótesis aorticas mecánicas. Nuevo fracaso para NOACs. ⬆️Tromboembolismo. ☑️Warfarina en casi…

May 16, 2023 · 36 shares · 48 followers View post →
Javier
@Javier_JimenoS · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 16, 2023 · 34 shares · 44 followers View post →
Nunzia Borrelli
@NunziaBorrell12 · X

RT @CardioBornan: DOAC y Válvula mecánica

May 16, 2023 · 15 shares · 1,715 followers View post →
Gonzalo L Alonso Salinas
@Gontxi7 · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 16, 2023 · 34 shares · 1,616 followers View post →
William Soler
@William11SH · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 16, 2023 · 34 shares · 97 followers View post →
Ana Cris
@AnaCrisA_R · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 16, 2023 · 34 shares · 586 followers View post →
Sacacorcho
@DDennymen · X

RT @Tomas_MA_Cardio: Apixaban vs Warfarina en prótesis aorticas mecánicas. Nuevo fracaso para NOACs. ⬆️Tromboembolismo. ☑️Warfarina en casi…

May 16, 2023 · 36 shares · 9 followers View post →
Luis Martinez Dolz
@luismdolz · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 16, 2023 · 34 shares · 385 followers View post →
trombo.info
@tromboinfo · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 16, 2023 · 34 shares · 1,591 followers View post →
Juan Felipe
@Juanfebeme · X

RT @Tomas_MA_Cardio: Apixaban vs Warfarina en prótesis aorticas mecánicas. Nuevo fracaso para NOACs. ⬆️Tromboembolismo. ☑️Warfarina en casi…

May 16, 2023 · 36 shares · 25 followers View post →
Onofre Casas Castro
@onofre_casas · X

RT @Tomas_MA_Cardio: Apixaban vs Warfarina en prótesis aorticas mecánicas. Nuevo fracaso para NOACs. ⬆️Tromboembolismo. ☑️Warfarina en casi…

May 16, 2023 · 36 shares · 110 followers View post →
Ricardo
@ricardoconsua · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 16, 2023 · 34 shares · 236 followers View post →
Juanmarcosgg
@juanmarcosgg · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 16, 2023 · 34 shares · 511 followers View post →
Lilia Andrea
@LiliaAndreataf1 · X

RT @Tomas_MA_Cardio: Apixaban vs Warfarina en prótesis aorticas mecánicas. Nuevo fracaso para NOACs. ⬆️Tromboembolismo. ☑️Warfarina en casi…

May 16, 2023 · 36 shares · 378 followers View post →
Diego Moreno
@mo45436785 · X

RT @Tomas_MA_Cardio: Apixaban vs Warfarina en prótesis aorticas mecánicas. Nuevo fracaso para NOACs. ⬆️Tromboembolismo. ☑️Warfarina en casi…

May 16, 2023 · 36 shares · 47 followers View post →
ALEJANDRO
@alejandu1978 · X

RT @Tomas_MA_Cardio: Apixaban vs Warfarina en prótesis aorticas mecánicas. Nuevo fracaso para NOACs. ⬆️Tromboembolismo. ☑️Warfarina en casi…

May 16, 2023 · 36 shares · 15 followers View post →
Orlando RPN
@OrlandoRPN · X

RT @Tomas_MA_Cardio: Apixaban vs Warfarina en prótesis aorticas mecánicas. Nuevo fracaso para NOACs. ⬆️Tromboembolismo. ☑️Warfarina en casi…

May 16, 2023 · 36 shares · 93,606 followers View post →
Adrian Maya
@AdrianMaya · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 16, 2023 · 34 shares · 375 followers View post →
Elio Martín Gutiérrez MD MsC PhD
@cirujano_cardio · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 16, 2023 · 34 shares · 240 followers View post →
Roberto Ramos
@Routhberth · X

RT @Tomas_MA_Cardio: Apixaban vs Warfarina en prótesis aorticas mecánicas. Nuevo fracaso para NOACs. ⬆️Tromboembolismo. ☑️Warfarina en casi…

May 16, 2023 · 36 shares · 309 followers View post →
Cosmo.
@NavyCosmo · X

RT @Tomas_MA_Cardio: Apixaban vs Warfarina en prótesis aorticas mecánicas. Nuevo fracaso para NOACs. ⬆️Tromboembolismo. ☑️Warfarina en casi…

May 16, 2023 · 36 shares · 420 followers View post →
Rubén Martín
@RubenMatins · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 16, 2023 · 34 shares · 460 followers View post →
José Mª Gª Quintana
@jose_g_quintana · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 16, 2023 · 34 shares · 850 followers View post →
Francisco Julián
@Currojulian · X

RT @Tomas_MA_Cardio: Apixaban vs Warfarina en prótesis aorticas mecánicas. Nuevo fracaso para NOACs. ⬆️Tromboembolismo. ☑️Warfarina en casi…

May 16, 2023 · 36 shares · 333 followers View post →
perropanson
@citarabino · X

RT @Tomas_MA_Cardio: Apixaban vs Warfarina en prótesis aorticas mecánicas. Nuevo fracaso para NOACs. ⬆️Tromboembolismo. ☑️Warfarina en casi…

May 16, 2023 · 36 shares · 1,448 followers View post →
Alejandro I. Pérez Cabeza
@alejandroipc2 · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 16, 2023 · 34 shares · 1,168 followers View post →
David de las Cuevas
@DaviddlCuevas · X

RT @Tomas_MA_Cardio: Apixaban vs Warfarina en prótesis aorticas mecánicas. Nuevo fracaso para NOACs. ⬆️Tromboembolismo. ☑️Warfarina en casi…

May 16, 2023 · 36 shares · 1,398 followers View post →
Felix Valencia
@FelixValencia10 · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 16, 2023 · 34 shares · 1,713 followers View post →
ZagasYum
@zagasyum18 · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 16, 2023 · 34 shares · 215 followers View post →
David de las Cuevas
@DaviddlCuevas · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 16, 2023 · 34 shares · 1,398 followers View post →
magallanero
@gandhi19 · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 16, 2023 · 34 shares · 99 followers View post →
Joaquín Morera ❤️‍
@joaqmorera · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 16, 2023 · 34 shares · 19,389 followers View post →
Roberto Gutiérrez
@DrRobertoGuti · X

RT @Tomas_MA_Cardio: Apixaban vs Warfarina en prótesis aorticas mecánicas. Nuevo fracaso para NOACs. ⬆️Tromboembolismo. ☑️Warfarina en casi…

May 16, 2023 · 36 shares · 785 followers View post →
J.G. Córdoba
@JGCorSo · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 16, 2023 · 34 shares · 927 followers View post →
fausto heredia z.
@drfherediaz · X

RT @CardioBornan: DOAC y Válvula mecánica

May 16, 2023 · 15 shares · 4,376 followers View post →
fabio rodriguez
@FabioDRodriguez · X

RT @CardioBornan: DOAC y Válvula mecánica

May 16, 2023 · 15 shares · 83 followers View post →
ViConejero
@ViConejero · X

RT @Tomas_MA_Cardio: Apixaban vs Warfarina en prótesis aorticas mecánicas. Nuevo fracaso para NOACs. ⬆️Tromboembolismo. ☑️Warfarina en casi…

May 16, 2023 · 36 shares · 1,129 followers View post →
EOLO MORANDI JR.
@eolojr · X

RT @Tomas_MA_Cardio: Apixaban vs Warfarina en prótesis aorticas mecánicas. Nuevo fracaso para NOACs. ⬆️Tromboembolismo. ☑️Warfarina en casi…

May 16, 2023 · 36 shares · 543 followers View post →
Gabriel Puche, MD/PhD
@gabi_puchepalao · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 16, 2023 · 34 shares · 8,371 followers View post →
Faby G.
@Fabiolaghh · X

RT @CardioBornan: DOAC y Válvula mecánica

May 16, 2023 · 15 shares · 410 followers View post →
Juan Senior
@jsenior64 · X

RT @Felipediezhoyo: #ACOD de nuevo, en este caso #apixabán

May 16, 2023 · 34 shares · 11,089 followers View post →
Felipe Díez del Hoyo
@Felipediezhoyo · X

#ACOD de nuevo, en este caso #apixabán

May 16, 2023 · 123 likes · 34 shares · 23,996 followers View post →
Jorge Demartino
@JorgeDemartino1 · X

RT @CardioBornan: DOAC y Válvula mecánica

May 16, 2023 · 15 shares · 314 followers View post →
levanlam
@levanlam0202 · X

Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve https://t.co/dNn80mhtPX

May 16, 2023 · 8 followers View post →
Seba GZ, MD, MSc
@sebagz1 · X

RT @CardioBornan: DOAC y Válvula mecánica

May 16, 2023 · 15 shares · 1,642 followers View post →
Kathrin Eller
@EllerKathrin · X

RT @gunnar_heine: Further Evidence for the 3 No's 4 NOACs PROACT Xa Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve…

May 12, 2023 · 1 share · 654 followers View post →
Gunnar Henrik Heine
@gunnar_heine · X

Further Evidence for the 3 No's 4 NOACs PROACT Xa Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | NEJM Evidence https://t.co/ZIBHI7PjS6 (Illustation by Mark A. Crowther, Aubrey E. Jones and Daniel M. Witt) https://t.co/KlHWdk936J

May 12, 2023 · 2 likes · 1 share · 2,418 followers View post →
Marko Banovic
@MarkoBanovic80 · X

RT @homam_heartdoc: Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | NEJM Evidence https://t.co/CKjeocwZHk

May 11, 2023 · 7 shares · 70 followers View post →
Glenn Garner
@garn7574 · X

RT @JudsonBWilliams: Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | NEJM Evidence Kudos ⁦@RenatoDLopes1⁩ and ⁦@Art…

May 10, 2023 · 3 shares · 88 followers View post →
Nelson Barrera, MD, MMS
@TheVash12 · X

Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | NEJM Evidence https://t.co/2fahpAGblo

May 10, 2023 · 4 likes · 728 followers View post →
名前
@akkiii0830 · X

Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | NEJM Evidence ダメだったかー https://t.co/eXHmJcUUo6

May 10, 2023 · 247 followers View post →
Serendip
@serendip3134 · X

A question that needed to be answered. Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | NEJM Evidence https://t.co/4wVFzvc5AT

May 9, 2023 · 1,377 followers View post →
Sreekanth Shetty
@sreekanthshetty · X

RT @JudsonBWilliams: Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | NEJM Evidence Kudos ⁦@RenatoDLopes1⁩ and ⁦@Art…

May 9, 2023 · 3 shares · 932 followers View post →
Davorin Sef
@DavorinSef · X

RT @homam_heartdoc: Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | NEJM Evidence https://t.co/CKjeocwZHk

May 9, 2023 · 7 shares · 104 followers View post →
Poonam Velagapudi
@Pooh_Velagapudi · X

RT @JudsonBWilliams: Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | NEJM Evidence Kudos ⁦@RenatoDLopes1⁩ and ⁦@Art…

May 9, 2023 · 3 shares · 11,746 followers View post →
Rebekka Adamson, PharmD, BCCP
@RebekkaAnn · X

RT @adam_dr_: "Inhibition of factor Xa seems insufficient to prevent valve thrombosis or thromboembolism in patients with an On-X mechanica…

May 9, 2023 · 5 shares · 276 followers View post →
Paramvir Chauhan MD
@paramvir_dr · X

RT @md_arianemacedo: No room for using DOACs in patients with mechanical aortic valves! Congrats @TYWangMD, @RenatoDLopes1, and all authors…

May 8, 2023 · 14 shares · 318 followers View post →
Ahan Kayastha
@ahankayastha · X

RT @md_arianemacedo: No room for using DOACs in patients with mechanical aortic valves! Congrats @TYWangMD, @RenatoDLopes1, and all authors…

May 8, 2023 · 14 shares · 67 followers View post →
Mohammed Alomar
@mealomar · X

RT @md_arianemacedo: No room for using DOACs in patients with mechanical aortic valves! Congrats @TYWangMD, @RenatoDLopes1, and all authors…

May 8, 2023 · 14 shares · 404 followers View post →
Judson Williams
@JudsonBWilliams · X

Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | NEJM Evidence Kudos ⁦@RenatoDLopes1⁩ and ⁦@ArtivionInc⁩ for this important work https://t.co/KhzWn2PJ5R

May 8, 2023 · 13 likes · 3 shares · 564 followers View post →
Tulio Caldonazo
@TulioCaldonazo · X

RT @homam_heartdoc: Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | NEJM Evidence https://t.co/CKjeocwZHk

May 8, 2023 · 7 shares · 2,085 followers View post →
Linda
@wordfinga · X

RT @homam_heartdoc: Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | NEJM Evidence https://t.co/CKjeocwZHk

May 8, 2023 · 7 shares · 4,581 followers View post →
Medicina
@envelhecercom · X

RT @roca_ferran: Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve https://t.co/DS4nFbY2fZ

May 8, 2023 · 1 share · 50 followers View post →
Susie Shapiro
@shapiro_susie · X

RT @md_arianemacedo: No room for using DOACs in patients with mechanical aortic valves! Congrats @TYWangMD, @RenatoDLopes1, and all authors…

May 8, 2023 · 14 shares · 673 followers View post →
Diego Sánchez Valenzuela
@difersan2 · X

RT @homam_heartdoc: Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | NEJM Evidence https://t.co/CKjeocwZHk

May 8, 2023 · 7 shares · 986 followers View post →
Ferran Roca
@roca_ferran · X

Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve https://t.co/DS4nFbY2fZ

May 8, 2023 · 2 likes · 1 share · 2,192 followers View post →
Antoine Bejjani, MD
@AntoineBejjani_ · X

RT @md_arianemacedo: No room for using DOACs in patients with mechanical aortic valves! Congrats @TYWangMD, @RenatoDLopes1, and all authors…

May 8, 2023 · 14 shares · 868 followers View post →
Jose Daniel Mosquera Lozano
@jdmosqueral · X

Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | NEJM Evidence https://t.co/4u0xkcHjji

May 8, 2023 · 233 followers View post →
Álvaro Dubois-Silva
@AlvaroDibua · X

Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | NEJM Evidence https://t.co/C9qP63N602

May 8, 2023 · 3 likes · 267 followers View post →
Kadyraliev Bakytbek
@BakytbekKadyral · X

RT @homam_heartdoc: Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | NEJM Evidence https://t.co/CKjeocwZHk

May 8, 2023 · 7 shares · 102 followers View post →
Mahmoud Qutb
@MahmoudTony19 · X

RT @md_arianemacedo: No room for using DOACs in patients with mechanical aortic valves! Congrats @TYWangMD, @RenatoDLopes1, and all authors…

May 8, 2023 · 14 shares · 244 followers View post →
Michel Pompeu Sá
@M_Pompeu_Sa_MD · X

RT @homam_heartdoc: Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | NEJM Evidence https://t.co/CKjeocwZHk

May 8, 2023 · 7 shares · 5,397 followers View post →
Silvio A. Ñamendys-Silva
@snamendys · X

Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | NEJM Evidence https://t.co/tPZMngMviX

May 8, 2023 · 3,684 followers View post →
Faby G.
@Fabiolaghh · X

RT @md_arianemacedo: No room for using DOACs in patients with mechanical aortic valves! Congrats @TYWangMD, @RenatoDLopes1, and all authors…

May 8, 2023 · 14 shares · 410 followers View post →
Homam Ibrahim MD FACC
@homam_heartdoc · X

Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | NEJM Evidence https://t.co/CKjeocwZHk

May 8, 2023 · 11 likes · 7 shares · 197 followers View post →
Mahmoud Qutb
@MahmoudTony19 · X

RT @adam_dr_: "Inhibition of factor Xa seems insufficient to prevent valve thrombosis or thromboembolism in patients with an On-X mechanica…

May 8, 2023 · 5 shares · 244 followers View post →
Axel Hiram Hdz
@axelhiram · X

RT @md_arianemacedo: No room for using DOACs in patients with mechanical aortic valves! Congrats @TYWangMD, @RenatoDLopes1, and all authors…

May 8, 2023 · 14 shares · 458 followers View post →
Syed Saad Mahmood, MD
@SaadMahmoodMD · X

RT @md_arianemacedo: No room for using DOACs in patients with mechanical aortic valves! Congrats @TYWangMD, @RenatoDLopes1, and all authors…

May 7, 2023 · 14 shares · 1,110 followers View post →
Joseph Gurion MD
@dr_Bpargali · X

RT @adam_dr_: "Inhibition of factor Xa seems insufficient to prevent valve thrombosis or thromboembolism in patients with an On-X mechanica…

May 7, 2023 · 5 shares · 596 followers View post →
Ricky Turgeon PharmD
@Ricky_Turgeon · X

RT @md_arianemacedo: No room for using DOACs in patients with mechanical aortic valves! Congrats @TYWangMD, @RenatoDLopes1, and all authors…

May 7, 2023 · 14 shares · 1,599 followers View post →
Ariane V. Scarlatelli Macedo
@md_arianemacedo · X

RT @adam_dr_: "Inhibition of factor Xa seems insufficient to prevent valve thrombosis or thromboembolism in patients with an On-X mechanica…

May 7, 2023 · 5 shares · 1,680 followers View post →
Cephas Ke-on Avoka
@AvokaKeon · X

RT @adam_dr_: "Inhibition of factor Xa seems insufficient to prevent valve thrombosis or thromboembolism in patients with an On-X mechanica…

May 7, 2023 · 5 shares · 547 followers View post →
Meena Madhur
@CVimmunology · X

RT @md_arianemacedo: No room for using DOACs in patients with mechanical aortic valves! Congrats @TYWangMD, @RenatoDLopes1, and all authors…

May 7, 2023 · 14 shares · 1,930 followers View post →
Eric H Yang, MD
@datsunian · X

RT @md_arianemacedo: No room for using DOACs in patients with mechanical aortic valves! Congrats @TYWangMD, @RenatoDLopes1, and all authors…

May 7, 2023 · 14 shares · 5,388 followers View post →
Adam Alhassan MD, MPH
@adam_dr_ · X

"Inhibition of factor Xa seems insufficient to prevent valve thrombosis or thromboembolism in patients with an On-X mechanical aortic valve." Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | NEJM Evidence https://t.co/m18fImkwxo

May 7, 2023 · 15 likes · 5 shares · 393 followers View post →
Casey McQuade, MD, MS Ed.
@CaseyMcQuadeMD · X

RT @md_arianemacedo: No room for using DOACs in patients with mechanical aortic valves! Congrats @TYWangMD, @RenatoDLopes1, and all authors…

May 7, 2023 · 14 shares · 1,158 followers View post →
Ariane V. Scarlatelli Macedo
@md_arianemacedo · X

No room for using DOACs in patients with mechanical aortic valves! Congrats @TYWangMD, @RenatoDLopes1, and all authors for this important piece! Apixaban or Warfarin in Patients with an On-X Mechanical Aortic Valve | NEJM Evidence https://t.co/ouqI6gqmMe

May 7, 2023 · 39 likes · 14 shares · 1,680 followers View post →
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... 10.1056/EVIDoa2300067. Results: Apixaban did not demonstrate noninferiority to warfarin and is less effective than warfarin for the ...

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... 10.1056/NEJMoa1300615 Apixaban or Warfarin in Patients with an On ... org/doi/full/10.1056/EVIDoa2300067 - Rheumatic AF Rivaroxaban in ...

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