February 2024 PMID 38362554

Atrial fibrillation: pathophysiology, genetic and epigenetic mechanisms.

Manlio Vinciguerra, Dobromir Dobrev, Stanley Nattel

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Mentions

Peak: 3 in Feb 2024

across 2 sources since Feb 2024

Extended reach

19,727

potential audience

Total likes

234

Video views

14,436

Mentions per month

Feb 2024 – Jul 2025

Where it's discussed

X / Twitter3 posts
YouTube2 videos

AI synopsis

What people are saying

The overall tone reflects high interest, with comments emphasizing the significance of genetic and epigenetic mechanisms in AF, such as 'groundbreaking' research and calls to 'consider' new approaches. Words like 'important' and references to 'advances' contribute to perceived moderate engagement and potential impact, indicating that the community values the study's contribution while not deeply dissecting its methodology.

AgreementModerate agreement

Most discussions acknowledge the importance of the article's insights into AF mechanisms, indicating general agreement with its findings.

InterestHigh interest

Participants show high interest, frequently referencing the relevance of genetic and epigenetic research in AF.

EngagementModerate engagement

There is moderate engagement, with some discussing specific aspects of the publication, though most replies are brief or promotional.

ImpactModerate impact

Discussions suggest the publication could influence future research and clinical approaches, though evidence is mainly in the form of recognition and interest.

Abstract in brief

Atrial fibrillation (AF) is the most common supraventricular arrhythmia, affecting up to 10% of elderly people, with its prevalence increasing with age and varying across different populations and ethnicities.
Recent research, including Genome Wide Association Studies (GWAS), has identified over 100 genetic loci linked to AF, highlighting mechanisms such as inflammation, electrical abnormalities, and structural changes in the heart.
Advances in understanding epigenetic mechanisms like noncoding RNAs, DNA methylation, and histone modification have helped reveal how genetic and epigenetic factors interact to influence AF development, with notable differences based on ethnicity.]

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All mentions

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Understanding PPG: Its Role in Wearables and Heart Health

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Dr Cailbhe Doherty · Jul 5, 2025 348 views

Niccolo Bonini

@BoniniNiccolo · X

RT @LiverpoolCCS: Atrial fibrillation: pathophysiology, genetic and epigenetic mechanisms #Afib @LHCHFT @LJMU_Health @LivHPartners https:/…

Feb 1, 2024 · 2 shares · 108 followers View post →

Liverpool Health Partners

@LivHPartners · X

RT @LiverpoolCCS: Atrial fibrillation: pathophysiology, genetic and epigenetic mechanisms #Afib @LHCHFT @LJMU_Health @LivHPartners https:/…

Feb 1, 2024 · 2 shares · 3,694 followers View post →

Liverpool Centre for Cardiovascular Science

@LiverpoolCCS · X

Atrial fibrillation: pathophysiology, genetic and epigenetic mechanisms #Afib @LHCHFT @LJMU_Health @LivHPartners https://t.co/DTYP6FlYCV https://t.co/DeU3qo58mD

Feb 1, 2024 · 7 likes · 2 shares · 1,477 followers View post →