Sci Adv February 2024 PMID 38394195

Waning immunity and IgG4 responses following bivalent mRNA boosting.

Ninaad Lasrado, Ai-Ris Y Collier, Jessica Miller, Nicole P Hachmann, Jinyan Liu, Trisha Anand, Esther A Bondzie, Jana L Fisher, Camille R Mazurek, Robert C Patio, Stefanie L Rodrigues, Marjorie Rowe, Nehalee Surve, Darren M Ty, Cindy Wu

Full text PDF Download social card

Mentions

175

Peak: 45 in Jun 2025

across 3 sources since Feb 2024

Extended reach

3,469,594

potential audience

Total likes

1,205

Video views

16,305

Mentions per month

Feb 2024 – Sep 2025

Where it's discussed

X / Twitter172 posts
YouTube2 videos
Bluesky1 posts

AI synopsis

What people are saying

The discussions include references to scientific updates, such as '2024 update: IgG4 antibodies' and debates on vaccine efficacy and immune response, with some comments expressing concern over IgG4's role in immunity, while others dismiss it as misleading. The tone varies from inquisitive to skeptical, which explains the moderate scores for interest and engagement, highlighting ongoing debates about vaccine impact and immune behavior.

AgreementNeither agree nor disagree

Discussions display mixed opinions, with some skepticism or concern about the findings and implications of the study.

InterestModerate interest

Participants show a moderate level of curiosity, focusing on IgG4 responses and vaccine effects, though some dismiss or downplay the significance.

EngagementModerate engagement

Several discussions involve referencing scientific data, questioning interpretations, and sharing opinions, indicating a decent level of engagement.

ImpactNeutral impact

The overall influence of these discussions appears moderate, influencing some users’ perceptions but not leading to widespread consensus or action.

Abstract in brief

Bivalent mRNA COVID-19 vaccines, while initially effective, show limited durability in neutralizing XBB variants and tend to induce an immune response skewed towards IgG4 antibodies, which have less functional activity.
After bivalent boosting, antibody levels against newer XBB variants decrease rapidly within three months, and the immune response mainly targets the original virus strain, indicating immune imprinting.
A third dose with monovalent mRNA vaccines can boost a broader range of antibody isotypes, including those with stronger functional activity, suggesting different booster strategies might improve long-term protection.]

Read the full abstract

All mentions

2024 Insights on IgG4 Antibodies Post-mRNA COVID-19 Vaccination

This video explores recent research on IgG4 antibody responses observed after mRNA COVID-19 vaccination. It includes comparisons between vaccine types, effects of repeated exposure, waning immunity, and impacts on…

Merogenomics · Jun 11, 2025 16,134 views

COVID Prevention Insights and Vaccine Efficacy Updates

This episode explores current research on COVID prevention, including mask effectiveness and vaccine relevance. It also discusses waning immunity and immune responses after booster shots, emphasizing the need for…

Luci Gabel · Mar 16, 2024 171 views

Glen Cavanagh

@GlenC39114 · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCWvgS

Sep 16, 2025 · 4 shares · 2,134 followers View post →

Blusey Blue

@blusey_blue · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCWvgS

Sep 16, 2025 · 4 shares · 451 followers View post →

Anita Lancée

@APLancee · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCWvgS

Sep 16, 2025 · 4 shares · 1,057 followers View post →

robstonge

@robstonge11 · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCWvgS

Sep 16, 2025 · 4 shares · 984 followers View post →

Dr Dave Cartland BMedSc MBChB Ex-MRCGP

@CartlandDavid · X

Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCWvgS

Sep 16, 2025 · 12 likes · 4 shares · 304,907 followers View post →

Fer Plaie

@FPlaie · X

RT @LevreroAnne: @sudokuvariante @wagneregger ça fait un an que certains chercheurs alertent sur le sujet https://t.co/5c8ye1oJw2

Aug 29, 2025 · 2 shares · 1,419 followers View post →

AnneLevrero

@LevreroAnne · X

@sudokuvariante @wagneregger ça fait un an que certains chercheurs alertent sur le sujet https://t.co/5c8ye1oJw2

Aug 29, 2025 · 5 likes · 2 shares · 249 followers View post →

John 2.1

@notambiturner · X

@UnrealBluegrass https://t.co/iwe0Z7e8Fe

Aug 28, 2025 · 503 followers View post →

Peter Suzman

@Biomaven · X

@SolidEvidence Waning immunity and IgG4 responses following bivalent mRNA boosting https://t.co/IznIEnFaJN

Aug 20, 2025 · 27 likes · 8,653 followers View post →

Richard Cowley

@RCowley185R · X

RT @merogenomics:

Aug 4, 2025 · 3 shares · 691 followers View post →

ZOGOD

@Scamdemics1984 · X

@RealRobCropton @arva61138 @Faberkat They said widespread misinformation more like widespread truth. IgG4 related disease is real. https://t.co/MDIstJr6tv

Jul 11, 2025 · 2,258 followers View post →

John 2.1

@notambiturner · X

@alslovinglife https://t.co/iwe0Z7eGuM

Jul 9, 2025 · 503 followers View post →

highroadwins

@canoecurves · X

@vejon_health @AlexBerenson https://t.co/nUF0hrKV80

Jul 7, 2025 · 276 followers View post →

highroadwins

@canoecurves · X

@AlexBerenson https://t.co/nUF0hrKV80

Jul 7, 2025 · 276 followers View post →

highroadwins

@canoecurves · X

2024 update: IgG4 antibodies post-mRNA vaccination (update #181) https://t.co/X9UipkIBSX via @YouTube @AlexBerenson

Jul 7, 2025 · 276 followers View post →

John 2.1

@notambiturner · X

@jonathanstea @HislopMD COVID 19 jabs "boost" immunity? You sure? https://t.co/iwe0Z7e8Fe

Jul 6, 2025 · 2 likes · 503 followers View post →

John 2.1

@notambiturner · X

@glvazquez @DrNeilStone https://t.co/iwe0Z7e8Fe

Jul 6, 2025 · 503 followers View post →

John 2.1

@notambiturner · X

@pipobulg @DrNeilStone https://t.co/iwe0Z7e8Fe

Jul 6, 2025 · 503 followers View post →

Occam's Razor

@occamsrazor461 · X

https://t.co/BQcTp6U20z

Jul 1, 2025 · 1,515 followers View post →

Lori

@l8deis · X

2024 update: IgG4 antibodies post-mRNA vaccination (update #181) https://t.co/i8h5uENNco via @YouTube

Jun 28, 2025 · 1 like · 2,051 followers View post →

ライアン

@raian932494 · X

@foldsproteins @marycroft557011 @HallMX2003 @grok @amico @MetabolicFactor https://t.co/QA06yDthGV https://t.co/0N9hNAKPAH https://t.co/z0aL6VnxKE https://t.co/7Z9wZMqUf5

Jun 24, 2025 · 2 followers View post →

bcorgan0

@bcorgan0 · X

RT @merogenomics:

Jun 22, 2025 · 3 shares · 963 followers View post →

Fish Tank

@FishTanksSuck · X

RT @merogenomics:

Jun 18, 2025 · 3 shares · 667 followers View post →

Merogenomics

@merogenomics · X

Jun 18, 2025 · 10 likes · 3 shares · 2,808 followers View post →

EthanDoe20

@EthanDoe666 · X

@eneldiluvio @ClareCraigPath @dobssi source : https://t.co/jvy3g6Agma

Jun 18, 2025 · 1 like · 782 followers View post →

ZOGOD

@Scamdemics1984 · X

@TerryPolevoy @Humanspective https://t.co/Lwsw9CMNpM

Jun 17, 2025 · 2,258 followers View post →

ZOGOD

@Scamdemics1984 · X

@markwarling3 Sounds like a pandemic of the vaccinated. IgG4 related disease. https://t.co/uxAJrG2AST

Jun 17, 2025 · 1 like · 2,258 followers View post →

morel roger

@rogermorel65 · X

RT @tatiann69922625: https://t.co/JvG68P4plF Merogenomics Mise à jour 2024 : anticorps IgG4 après vaccination ARNm (mise à jour n° 181)…

Jun 16, 2025 · 10 shares · 50 followers View post →

inihcnarf

@inihcnarf · X

RT @tatiann69922625: https://t.co/JvG68P4plF Merogenomics Mise à jour 2024 : anticorps IgG4 après vaccination ARNm (mise à jour n° 181)…

Jun 16, 2025 · 10 shares · 1,725 followers View post →

Monneret Valérie

@sstellalluna · X

RT @tatiann69922625: https://t.co/JvG68P4plF Merogenomics Mise à jour 2024 : anticorps IgG4 après vaccination ARNm (mise à jour n° 181)…

Jun 16, 2025 · 10 shares · 132 followers View post →

Ed Dreamer

@EdDreamer8 · X

RT @tatiann69922625: https://t.co/JvG68P4plF Merogenomics Mise à jour 2024 : anticorps IgG4 après vaccination ARNm (mise à jour n° 181)…

Jun 16, 2025 · 10 shares · 944 followers View post →

morel huguette

@guetty353535 · X

RT @tatiann69922625: https://t.co/JvG68P4plF Merogenomics Mise à jour 2024 : anticorps IgG4 après vaccination ARNm (mise à jour n° 181)…

Jun 16, 2025 · 10 shares · 1,146 followers View post →

Natalia Nausica

@NataliaNausica · X

RT @tatiann69922625: https://t.co/JvG68P4plF Merogenomics Mise à jour 2024 : anticorps IgG4 après vaccination ARNm (mise à jour n° 181)…

Jun 16, 2025 · 10 shares · 4,935 followers View post →

Morkaïus

@NauleauFrederic · X

RT @tatiann69922625: https://t.co/JvG68P4plF Merogenomics Mise à jour 2024 : anticorps IgG4 après vaccination ARNm (mise à jour n° 181)…

Jun 16, 2025 · 10 shares · 406 followers View post →

Cd'Albi

@CHDLA · X

RT @tatiann69922625: https://t.co/JvG68P4plF Merogenomics Mise à jour 2024 : anticorps IgG4 après vaccination ARNm (mise à jour n° 181)…

Jun 16, 2025 · 10 shares · 460 followers View post →

G.Wenger

@bricolix · X

RT @tatiann69922625: https://t.co/JvG68P4plF Merogenomics Mise à jour 2024 : anticorps IgG4 après vaccination ARNm (mise à jour n° 181)…

Jun 16, 2025 · 10 shares · 1,471 followers View post →

Nass Rubis

@nbenmessikh0 · X

RT @tatiann69922625: https://t.co/JvG68P4plF Merogenomics Mise à jour 2024 : anticorps IgG4 après vaccination ARNm (mise à jour n° 181)…

Jun 16, 2025 · 10 shares · 1,045 followers View post →

LieselWeppen

@lieselweppen · X

RT @tatiann69922625: https://t.co/JvG68P4plF Merogenomics Mise à jour 2024 : anticorps IgG4 après vaccination ARNm (mise à jour n° 181)…

Jun 16, 2025 · 10 shares · 4,663 followers View post →

LE COLLECTIF

@tatiann69922625 · X

Jun 16, 2025 · 21 likes · 10 shares · 63,070 followers View post →

Bożena Gawerska

@BozenaGawerska · X

https://t.co/VCB3UbmPCw

Jun 15, 2025 · 13 followers View post →

GrinerATodd

@supertodd1 · X

RT @P1231032850: 5/ @merogenomics Dr. Mikolaj Raszek https://t.co/u9uwestSdQ https://t.co/NxFAfcVhFh

Jun 14, 2025 · 1 share · 1,531 followers View post →

P123

@P1231032850 · X

5/ @merogenomics Dr. Mikolaj Raszek https://t.co/u9uwestSdQ https://t.co/NxFAfcVhFh

Jun 14, 2025 · 1 like · 1 share · 3,158 followers View post →

André van der Bij

@AndrewMacCloud · X

2024 update: IgG4 antibodies post-mRNA vaccination https://t.co/oSDWDzYjMJ

Jun 14, 2025 · 462 followers View post →

M.V.

@maria_vansant · X

RT @Nordenslys: En daar komt dan nog bij dat IgG4 waarden ook onverminderd hoog blijven. Een andere red flag. https://t.co/46sCIoQHu2

Jun 13, 2025 · 2 shares · 5,720 followers View post →

Jan Eerenberg

@jan_eerenberg · X

RT @Nordenslys: En daar komt dan nog bij dat IgG4 waarden ook onverminderd hoog blijven. Een andere red flag. https://t.co/46sCIoQHu2

Jun 13, 2025 · 2 shares · 201 followers View post →

ZOGOD

@Scamdemics1984 · X

@Habundia It's not just cancer you have to worry about. https://t.co/R7k933nkW0

Jun 13, 2025 · 1 like · 2,258 followers View post →

Meltdown Observer

@Constantin22409 · X

https://t.co/TaAqqbgqXx

Jun 12, 2025 · 331 followers View post →

Governmentsandallbanksliekillandstealworldwide6969

@Politicarilazu1 · X

https://t.co/1uIyRmgWHe

Jun 12, 2025 · 392 followers View post →

Laila Macka

@LailaMacka7390 · X

https://t.co/A0gGBgYlDC

Jun 12, 2025 · 382 followers View post →

Norman Gartner

@NothinFerFree · X

@GVDBossche IgG4 and immunilogic tolerance to spice protein. Very important update Dr. Mikolaj Raszek: https://t.co/XTTFz4fWYh

Jun 12, 2025 · 7 followers View post →

@Kathy_Jankowski · X

https://t.co/d4V8wH06oq

Jun 12, 2025 · 766 followers View post →

Tracy

@xxtracy09xx · X

RT @xxtracy09xx: 2024 update: IgG4 antibodies post-mRNA vaccination (update #181) https://t.co/7awxIX7d7c via @YouTube

Jun 12, 2025 · 1 share · 1,176 followers View post →

Tracy

@xxtracy09xx · X

2024 update: IgG4 antibodies post-mRNA vaccination (update #181) https://t.co/7awxIX7d7c via @YouTube

Jun 12, 2025 · 1 like · 1 share · 1,176 followers View post →

Nordenslys #EalaFreaFresena - #StemZeWeg

@Nordenslys · X

En daar komt dan nog bij dat IgG4 waarden ook onverminderd hoog blijven. Een andere red flag. https://t.co/46sCIoQHu2

Jun 12, 2025 · 3 likes · 2 shares · 2,508 followers View post →

ごはん

@tamanegiR41120 · X

RT @vagaubond: Merogenomicsの2024年IgG4研究のまとめ動画より https://t.co/bwgQGfyjWz 不活化ワクチンでも繰り返し投与でIgG4確認 mRNAワクチンの反復投与でIgG4が誘導されNK細胞の活性が減少という研究ファイザ…

Jun 12, 2025 · 1 share · 467 followers View post →

vagaubond

@vagaubond · X

Merogenomicsの2024年IgG4研究のまとめ動画より https://t.co/bwgQGfyjWz 不活化ワクチンでも繰り返し投与でIgG4確認 mRNAワクチンの反復投与でIgG4が誘導されNK細胞の活性が減少という研究ファイザーよりもモデルナのほうがIgG4を誘導している既感染だとIgG4の誘導は少ない（抗原原罪？） https://t.co/vHAM30fsW9

Jun 12, 2025 · 1 share · 95 followers View post →

CanadaCommunity

@CDNCommunity · X

2024 update: IgG4 antibodies post-mRNA vaccination (update #181) https://t.co/0Zj5FCmmG8 via @YouTube

Jun 12, 2025 · 524 followers View post →

John Caprio

@Jmoe2222 · X

@CTCentinal IgG4 antibodies post-mRNA vaccination The latest scientific research on anti-spike IgG4 antibodies observed in individuals vaccinated with mRNA COVID-19 vaccines https://t.co/pjuslXZGMZ

Jun 11, 2025 · 338 followers View post →

Marcie Renee

@MarcieRenee1 · X

2024 update: IgG4 antibodies post-mRNA vaccination (update #181) https://t.co/hmFtUe8E96 via @YouTube

Jun 11, 2025 · 639 followers View post →

GrinerATodd

@supertodd1 · X

https://t.co/0MKSLuAd1r

Jun 11, 2025 · 1,531 followers View post →

Lifestream Vagabond

@Shinigami_Oni · X

https://t.co/MfFOSD8975

Jun 11, 2025 · 595 followers View post →

Edward James

@jame5878 · X

Dr Mikolaj Raszek IgG4 antibodies post mRNA injection https://t.co/bpz6IQ9FNS

Jun 11, 2025 · 1 like · 835 followers View post →

The Complaint Department

@ChrisSulli277 · X

https://t.co/RAIPgDrJa0 If u don't kno u better catch up. Dudes got the info fer real. Set aside some time. And do catch up with us

Jun 11, 2025 · 1,633 followers View post →

Dr Dave Cartland BMedSc MBChB Ex-MRCGP

@CartlandDavid · X

Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCWvgS

May 2, 2025 · 9 likes · 304,907 followers View post →

Glen Cavanagh

@GlenC39114 · X

RT @CartlandDavid: February 23, 2024 Waning immunity and IgG4 responses following bivalent mRNA boosting https://t.co/uzxWGTNcMn ... Our…

Apr 19, 2025 · 4 shares · 2,134 followers View post →

ChoiceNotCoercion

@ChXCoercion · X

RT @CartlandDavid: February 23, 2024 Waning immunity and IgG4 responses following bivalent mRNA boosting https://t.co/uzxWGTNcMn ... Our…

Apr 19, 2025 · 4 shares · 84 followers View post →

WAKE THE FLOCK UP!!

@ToniMontana406 · X

RT @CartlandDavid: February 23, 2024 Waning immunity and IgG4 responses following bivalent mRNA boosting https://t.co/uzxWGTNcMn ... Our…

Apr 19, 2025 · 4 shares · 1,458 followers View post →

GREAT GRANDMOTHER

@144KDNA · X

RT @CartlandDavid: February 23, 2024 Waning immunity and IgG4 responses following bivalent mRNA boosting https://t.co/uzxWGTNcMn ... Our…

Apr 19, 2025 · 4 shares · 6,954 followers View post →

Dr Dave Cartland BMedSc MBChB Ex-MRCGP

@CartlandDavid · X

February 23, 2024 Waning immunity and IgG4 responses following bivalent mRNA boosting https://t.co/uzxWGTNcMn ... Our data demonstrate that bivalent mRNA boosting may be limited by immune imprinting and that multiple mRNA immunizations may lead to IgG4 responses with poor

Apr 19, 2025 · 10 likes · 4 shares · 304,907 followers View post →

MBMarcellino

@MBitMarcellino · X

@roxmo Acorda pra vida, cara! ACORDA! https://t.co/ruw0dMgNv7 https://t.co/XRWF4VGVyU https://t.co/PAj2NYEuSC https://t.co/K6b69gOHLU https://t.co/OiZqDPyrbB https://t.co/zWDpOCQZJ4

Apr 5, 2025 · 83 followers View post →

MBMarcellino

@MBitMarcellino · X

@ducavendish @mab_sp125 @TuckerCarlson https://t.co/OiZqDPyZ19 A "eficácia"...

Mar 30, 2025 · 83 followers View post →

MBMarcellino

@MBitMarcellino · X

@ProfDenisePires https://t.co/OiZqDPyrbB

Mar 30, 2025 · 83 followers View post →

Path Of Hecate

@PathOfHecate · X

RT @R3DWyvern: @Tfunk_mcgee @Yash25571056 FYI science has shown that the vaccine messes with the immune system, specifically the worst resu…

Mar 28, 2025 · 1 share · 796 followers View post →

Maria Katapodi

@Kamaref · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCWvgS

Feb 22, 2025 · 3 shares · 2,587 followers View post →

Deanna Wagner

@Deanna13Prime · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCWvgS

Feb 22, 2025 · 3 shares · 419 followers View post →

Honeyda

@honeeyyda · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCWvgS

Feb 22, 2025 · 3 shares · 168 followers View post →

Dr Dave Cartland BMedSc MBChB Ex-MRCGP

@CartlandDavid · X

Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCWvgS

Feb 22, 2025 · 18 likes · 3 shares · 304,907 followers View post →

Che Yemani

@discoveryofme2 · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCX36q

Jan 25, 2025 · 9 shares · 39 followers View post →

Lord “The $cience™️” Kramdar

@Precliner · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCX36q

Jan 24, 2025 · 9 shares · 1,370 followers View post →

Sab18

@Sab98910181 · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCX36q

Jan 24, 2025 · 9 shares · 110 followers View post →

Trevor Thistle

@ttbaldy · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCX36q

Jan 24, 2025 · 9 shares · 355 followers View post →

Nadim Darwich

@ndgenomics · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCX36q

Jan 24, 2025 · 9 shares · 15 followers View post →

Mike Letizia

@68grt · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCX36q

Jan 24, 2025 · 9 shares · 791 followers View post →

Call Out the Holy Names & Be Happy

@Ch4ntHareKrsna · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCX36q

Jan 24, 2025 · 9 shares · 1,136 followers View post →

Citizens First!

@ilonat2016 · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCX36q

Jan 24, 2025 · 9 shares · 1,250 followers View post →

Breaking Out in Brazil

@out_brazil · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCX36q

Jan 24, 2025 · 9 shares · 5,501 followers View post →

Dr Dave Cartland BMedSc MBChB Ex-MRCGP

@CartlandDavid · X

Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCX36q

Jan 24, 2025 · 12 likes · 9 shares · 304,907 followers View post →

LenigeLiefde

@lenigeliefde · X

@SGeysenbergh @Eva_DK_ Welke immunoglobines is ook van belang! https://t.co/ahHEuidX80

Jan 12, 2025 · 16,369 followers View post →

Sensus communis

@SueSensus · X

RT @CartlandDavid: February 23, 2024 Waning immunity and IgG4 responses following bivalent mRNA boosting https://t.co/uzxWGTNKBV ... Our…

Jan 2, 2025 · 5 shares · 1,468 followers View post →

Evie *****

@Evie707656912 · X

RT @CartlandDavid: February 23, 2024 Waning immunity and IgG4 responses following bivalent mRNA boosting https://t.co/uzxWGTNKBV ... Our…

Jan 2, 2025 · 5 shares · 2,723 followers View post →

Lachie Grahame

@LGrahame12676 · X

RT @CartlandDavid: February 23, 2024 Waning immunity and IgG4 responses following bivalent mRNA boosting https://t.co/uzxWGTNKBV ... Our…

Jan 2, 2025 · 5 shares · 343 followers View post →

Sophia Dahl

@sophiadahl1 · X

RT @CartlandDavid: February 23, 2024 Waning immunity and IgG4 responses following bivalent mRNA boosting https://t.co/uzxWGTNKBV ... Our…

Jan 2, 2025 · 5 shares · 82,382 followers View post →

Rt Hon Sir Quasimodo Esq.

@ShtBlackwood · X

RT @CartlandDavid: February 23, 2024 Waning immunity and IgG4 responses following bivalent mRNA boosting https://t.co/uzxWGTNKBV ... Our…

Jan 2, 2025 · 5 shares · 1,991 followers View post →

Dr Dave Cartland BMedSc MBChB Ex-MRCGP

@CartlandDavid · X

Jan 2, 2025 · 17 likes · 5 shares · 304,907 followers View post →

Cristina Fossati

@nontiscordardi3 · X

@Rotelli_MD https://t.co/05q0pFErO9 https://t.co/dhRAXL3xRo

Dec 18, 2024 · 77 followers View post →

Red Wyvern

@R3DWyvern · X

Nov 30, 2024 · 25 likes · 1 share · 939 followers View post →

Saban Ikic

@sas27bih · X

@hendrikstreeck Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances

Nov 21, 2024 · 5 followers View post →

K@'s Cartoons & Art for Humanity

@kats_cartoons · X

@Beat_It_Loser @CastanetNews https://t.co/rSphMkmEff https://t.co/E6YpdvQZ2Q https://t.co/EfDssklsls

Oct 22, 2024 · 1,283 followers View post →

LenigeLiefde

@lenigeliefde · X

@feliciahsiehsw @viinikka @chantz_y @CDCDirector @goddeketal https://t.co/ahHEuieuXy

Oct 19, 2024 · 16,369 followers View post →

LenigeLiefde

@lenigeliefde · X

@VPrasadMDMPH there is a problem with IgG4 and spike proteins which causes you to get certain side effects and a drop in your immunity, https://t.co/ahHEuieuXy

Oct 7, 2024 · 16,369 followers View post →

LenigeLiefde

@lenigeliefde · X

@alanlremick 1. Where is the substantiation, the study that supports your opinion here? 2. Just because there are other spike proteins doesn't mean it has fewer problems. The vaccine will take care of e.g. IgG4 production, which is problematic. https://t.co/ahHEuidX80

Oct 6, 2024 · 16,369 followers View post →

LenigeLiefde

@lenigeliefde · X

@cuntycatlady @ArrVee50 @richardhirschs1 Waning immunity and IgG4 responses following bivalent mRNA boosting https://t.co/ahHEuieuXy

Oct 3, 2024 · 1 like · 16,369 followers View post →

trillionofcells

@trillionofcells · X

@Roper_Lab @dense_evi @Scary7Dr @Pacto_Secreto @The_Seeadler @JonKnudson89269 @AndrewLazarus4 @CaryDavid722 @BurgerLab12 @PatrickSquirrel @cappsie @Lorenzo7127 @SirMasksALot @Monstercoyliar @SkepticalMutant @higgsri @ncdave4life @TMGFlorida @monyro5 @jtmayes3 @CarlSmytheCells @iXeno @crabb_vicki @Earthdriver @ktibus @exohalophiles @ChrisJohnsonMD @SecedeFromFools @TorySnyc @dirk_fasshauer @RonMortimer3 @mcfunny @lasikeyecenter1 @Hanky1844607 @davideyoungmd @Awithonelison @NoGlobalist778 @EugeneBu @AcampbelTeacher @EdwardDS15 @FillmoreWhite @VickiCoyle10019 @FUDyou2 @smith_john55 @TheCrystalBrian @ScooterScience @RndmStreetMedic @DebraBr81576310 @JordanA8156 @BlueLionBlog So does the covid vx!!! The vx'd cannot clear the spike. Ig4, baby. W a natural infection you get durable immunity as well as viral clearance. It's much safer to get covid than a covid vx. https://t.co/ErqFU4xicm

Oct 3, 2024 · 861 followers View post →

hamhead.eth

@HamHead5813 · X

@DopplerEffect93 @OUfan1987 @Debunk_the_Funk @BretWeinstein I just presented evidence. Are you choosing to ignore it? "Our data demonstrate that bivalent mRNA boosting may be limited by immune imprinting and that multiple mRNA immunizations may lead to IgG4 responses with poor functional activity." https://t.co/cU1Dsqpv4V

Oct 2, 2024 · 2 likes · 1 share · 3,009 followers View post →

Jujubmuse

@Jujubmuse · X

@michael_hoerger Another: https://t.co/jqISsRB3SA

Sep 28, 2024 · 382 followers View post →

Ros Maidment

@MaidmentRos · X

@Daltmann10 The worry is repeat boosters driving this.Change from IgG1 to IgG4 after 2 or 3 doses may explain reduced immunity in vaccinated rather than unvacc'ed. Here's one of many publications https://t.co/WTFTE3DpOW

Sep 28, 2024 · 4,904 followers View post →

clearavacc

@clearavacc · X

@Rnneholmsparke1 @Altitude2222 @Nils_Littorin @ETC_redaktionen @MakisMD https://t.co/rsKE46qY9i En mycket bra beskrivning. På hemsidan kanske du gick förbi där vi skriver om Sv40 som är själva ämnet i vaccinet som ger upphov till turbocancer. Läs gärna även Linda Söderholms berättelse https://t.co/NajQXB8Xjd

Sep 26, 2024 · 132 followers View post →

Crypto Customer Service

@CryptoCusServ · X

@liz_churchill10 https://t.co/nuNQsQdt87

Sep 22, 2024 · 196 followers View post →

ま

@MAGumi_Hikeshi · X

3ヶ月で上昇しその後感染でも上昇とか有りかなり煽っていたが… 図は以下Fig. 5 の IgG4 Month 6が6か月後 Science Advances 23 Feb 2024 Vol10, Issue8 https://t.co/4wroXYX0G2 「IgG4の功罪の誤解？」という論文もご紹介 Science Immunology 7 Feb 2023 Vol8, Issue81 https://t.co/B8BiFUnPhw https://t.co/flIzL1bwtZ

Aug 25, 2024 · 89 followers View post →

JaFreed

@JaFreed6 · X

@McCallaPE @djlange @KLVeritas Brian, mRNA vaccines work very differently than advertised. They go all over the body and make spike for weeks. This causes the body to view spike as an allergen, and the immune system changes the TYPE of antibodies it produces to a type called IgG4. https://t.co/1QHBH8E0e1

Aug 20, 2024 · 3 likes · 76 followers View post →

ま

@MAGumi_Hikeshi · X

RT @MAGumi_Hikeshi: @studiocorvo IgG 4 の話はその後6ヶ月後の測定の論文が出て https://t.co/3JvBBjaPOh 参照グラフはFig. 5 の IgG4 Month 6が6か月後で減少しています「IgG4の功罪の誤解？」と…

Aug 18, 2024 · 1 share · 89 followers View post →

Dr Dave Cartland BMedSc MBChB Ex-MRCGP

@CartlandDavid · X

@ivan_skava65522 @TheCornishPasty https://t.co/R6lzBCWvgS

Aug 15, 2024 · 304,907 followers View post →

ま

@MAGumi_Hikeshi · X

@studiocorvo IgG 4 の話はその後6ヶ月後の測定の論文が出て https://t.co/3JvBBjaPOh 参照グラフはFig. 5 の IgG4 Month 6が6か月後で減少しています「IgG4の功罪の誤解？」という論文もご紹介しておきます https://t.co/ghGAqPzyYn https://t.co/9urMJpqsq1

Aug 12, 2024 · 1 like · 1 share · 89 followers View post →

あるたまあか

@1Aonowakusei · X

二価mRNAブースト後のIgGサブクラスと機能的応答及び、一価mRNAブースト後のIgGサブクラスと機能的応答 https://t.co/F8WrLFFRPY

Aug 11, 2024 · 71 followers View post →

ま

@MAGumi_Hikeshi · X

RT @MAGumi_Hikeshi: @7xCzVz2knym9PSL 画像参照は https://t.co/3JvBBjaPOh [Waning immunity and IgG4 responses following bivalent mRNA boosting] Fi…

Jul 17, 2024 · 1 share · 89 followers View post →

ま

@MAGumi_Hikeshi · X

RT @MAGumi_Hikeshi: @7xCzVz2knym9PSL お返事ありがとうございます一応、6ヶ月後の測定は以下で見られますよ https://t.co/3JvBBjaPOh リンク先は抗原原罪? とありますがこれは別の似た物でも最初の抗体のみ産出されてしま…

Jul 17, 2024 · 1 share · 89 followers View post →

ま

@MAGumi_Hikeshi · X

@7xCzVz2knym9PSL 画像参照は https://t.co/3JvBBjaPOh [Waning immunity and IgG4 responses following bivalent mRNA boosting] Fig. 5. Antibody and Fc effector function profiling by systems serology following third monovalent mRNA immunization.

Jul 17, 2024 · 1 share · 89 followers View post →

ま

@MAGumi_Hikeshi · X

@7xCzVz2knym9PSL お返事ありがとうございます一応、6ヶ月後の測定は以下で見られますよ https://t.co/3JvBBjaPOh リンク先は抗原原罪? とありますがこれは別の似た物でも最初の抗体のみ産出されてしまい機能不全になるもので以下で確認、無かったようです https://t.co/2AM8up2Aya https://t.co/1U1XwHnCu8

Jul 17, 2024 · 1 share · 89 followers View post →

JaFreed

@JaFreed6 · X

@Laurie_Garrett The Covid vaccines cause immune damage via many pathways. Have you read the scientific literature, Laurie? https://t.co/1QHBH8Ey3z

Jul 13, 2024 · 76 followers View post →

あるたまあか

@1Aonowakusei · X

https://t.co/F8WrLFFRPY

Jul 9, 2024 · 71 followers View post →

Gaute Adler Nilsen

@GauteNilsen · X

RT @NannyNoisy: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/XrqfzXopUv

Jul 9, 2024 · 2 shares · 14,188 followers View post →

Noisy Nanny.

@NannyNoisy · X

Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/XrqfzXopUv

Jul 9, 2024 · 1 like · 2 shares · 400 followers View post →

googs

@glengooogs · X

@aftab_usa If your immune system struggles to clear a cytolitic virus would that be what long covid looks like? https://t.co/HQIacUHpNq https://t.co/cY3k5XwXB0 https://t.co/Lt74pVjDIe https://t.co/HGnEJQknPb

Jun 24, 2024 · 76 followers View post →

googs

@glengooogs · X

@DoctorKarl https://t.co/HGnEJQkVEJ

Jun 23, 2024 · 76 followers View post →

tim in thailand

@paulwall1133 · X

@ssps744444231 @yay_its_james https://t.co/GY7bkUJgRH

Jun 20, 2024 · 46 followers View post →

MoNoLongerKnows

@MoknowsMinimo · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCWvgS

May 9, 2024 · 4 shares · 1,402 followers View post →

Steve Bailey

@Sbailey232Steve · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCWvgS

May 9, 2024 · 4 shares · 796 followers View post →

BlueChipFuego

@JackKnifeJockey · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCWvgS

May 9, 2024 · 4 shares · 1,057 followers View post →

Maddie

@MadelineWa20933 · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCWvgS

May 9, 2024 · 4 shares · 2,332 followers View post →

Dr Dave Cartland BMedSc MBChB Ex-MRCGP

@CartlandDavid · X

Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCWvgS

May 9, 2024 · 9 likes · 4 shares · 304,907 followers View post →

STORMANGEL777

@stormangel777 · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCWvgS

Apr 19, 2024 · 6 shares · 4,720 followers View post →

Barry

@dolforwen · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCWvgS

Apr 19, 2024 · 6 shares · 417 followers View post →

Tokes

@Tokes29121154 · X

@Pingu71 @SWally1119586 @sonia_elijah @ABridgen https://t.co/zEOqpjs8Gg Source is there. I cant make you read, are you Dyslexic? Heres more. https://t.co/DTYWyeacql https://t.co/WDWrpyKsyj https://t.co/God5Ea51RO

Apr 19, 2024 · 179 followers View post →

Sunny409

@Sunny40958537 · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCWvgS

Apr 19, 2024 · 6 shares · 3,242 followers View post →

Boadicea

@woadismeRN · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCWvgS

Apr 19, 2024 · 6 shares · 613 followers View post →

UnderTinker

@UnderTinker · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCWvgS

Apr 19, 2024 · 6 shares · 346 followers View post →

Judy

@toonieloo · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCWvgS

Apr 19, 2024 · 6 shares · 520 followers View post →

Dr Dave Cartland BMedSc MBChB Ex-MRCGP

@CartlandDavid · X

Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCWvgS

Apr 19, 2024 · 21 likes · 6 shares · 304,907 followers View post →

Cristina Fossati

@nontiscordardi3 · X

@BiologiScienza https://t.co/IZmuDbNI18 https://t.co/dhRAXL301Q Qualche domanda bisognerebbe porsela. Sono vaccinata. Per questo cerco di aggiornarmi

Apr 16, 2024 · 77 followers View post →

Cristina Fossati

@nontiscordardi3 · X

@RobertoBurioni @LucioMalan Un parere su questo, se possibile https://t.co/IZmuDbNI18

Apr 15, 2024 · 1 like · 77 followers View post →

tim in thailand

@paulwall1133 · X

@Paul10376555 @Aleks_Lisitsyn https://t.co/GY7bkUJgRH

Apr 14, 2024 · 46 followers View post →

tim in thailand

@paulwall1133 · X

@Paul10376555 @Aleks_Lisitsyn https://t.co/GY7bkUJgRH

Apr 14, 2024 · 46 followers View post →

tim in thailand

@paulwall1133 · X

@Paul10376555 @Aleks_Lisitsyn https://t.co/GY7bkUJgRH

Apr 14, 2024 · 46 followers View post →

tim in thailand

@paulwall1133 · X

@Paul10376555 @Aleks_Lisitsyn https://t.co/GY7bkUJgRH

Apr 14, 2024 · 46 followers View post →

tim in thailand

@paulwall1133 · X

@Paul10376555 @Aleks_Lisitsyn https://t.co/GY7bkUJgRH

Apr 14, 2024 · 46 followers View post →

tim in thailand

@paulwall1133 · X

@Paul10376555 @Aleks_Lisitsyn https://t.co/GY7bkUJgRH

Apr 14, 2024 · 46 followers View post →

tim in thailand

@paulwall1133 · X

@Paul10376555 @Aleks_Lisitsyn https://t.co/GY7bkUJgRH

Apr 14, 2024 · 46 followers View post →

tim in thailand

@paulwall1133 · X

@Paul10376555 https://t.co/GY7bkUIJ29

Apr 14, 2024 · 46 followers View post →

tim in thailand

@paulwall1133 · X

@Paul10376555 https://t.co/GY7bkUJgRH

Apr 14, 2024 · 46 followers View post →

tim in thailand

@paulwall1133 · X

@Paul10376555 @Aleks_Lisitsyn https://t.co/GY7bkUJgRH

Apr 14, 2024 · 46 followers View post →

tim in thailand

@paulwall1133 · X

@Paul10376555 @Aleks_Lisitsyn https://t.co/GY7bkUJgRH

Apr 14, 2024 · 46 followers View post →

Laura Malter

@lauramalter · X

RT @lasradoN: Our new paper on immunity of bivalent mRNA boosters and IgG profiling, especially IgG4 responses after 3rd and 4th mRNA vacci…

Mar 28, 2024 · 4 shares · 1,413 followers View post →

A language buff

@Language_buff · X

@AlexBerenson https://t.co/XakwND9EYw

Mar 28, 2024 · 53 followers View post →

Random Carbon Atoms

@bboyneko · X

RT @lasradoN: Our new paper on immunity of bivalent mRNA boosters and IgG profiling, especially IgG4 responses after 3rd and 4th mRNA vacci…

Mar 27, 2024 · 4 shares · 256 followers View post →

Kinsey Kat

@KinseyKat1 · X

RT @AlexBerenson: Guess Dan Barouch doesn't understand "IgG4 nonsense" either. From his new paper: "mRNA immunizations may lead to IgG4 re…

Mar 27, 2024 · 14 shares · 395 followers View post →

BlueChipFuego

@JackKnifeJockey · X

RT @AlexBerenson: Guess Dan Barouch doesn't understand "IgG4 nonsense" either. From his new paper: "mRNA immunizations may lead to IgG4 re…

Mar 24, 2024 · 14 shares · 1,057 followers View post →

Pilgrim

@villagerssn · X

More on class switching. https://t.co/bIj9kVW5mS

Mar 22, 2024 · 2 likes · 2,634 followers View post →

Pilgrim

@villagerssn · X

@Debunk_the_Funk @dr_jon_l @AlexBerenson People might want to read the paper themselves instead of depending on funk's interpretation. Note in particular the part after "and that" https://t.co/bIj9kVW5mS https://t.co/fv7R1LQxew

Mar 22, 2024 · 5 likes · 2,634 followers View post →

Monopoli1944

@taverna72322 · X

RT @AlexBerenson: Guess Dan Barouch doesn't understand "IgG4 nonsense" either. From his new paper: "mRNA immunizations may lead to IgG4 re…

Mar 22, 2024 · 14 shares · 170 followers View post →

nobody in particular

@wortgewalt3 · X

@JennyB86654603 https://t.co/oCCs9UPztr https://t.co/X4yiaTTVXt https://t.co/NquoGJTcBj Was ich so auf die Schnelle parat habe. Vergesse meist, zu bookmarken.

Mar 22, 2024 · 1 like · 150 followers View post →

Kat Wallace

@ebalnolom1 · X

RT @AlexBerenson: Guess Dan Barouch doesn't understand "IgG4 nonsense" either. From his new paper: "mRNA immunizations may lead to IgG4 re…

Mar 21, 2024 · 14 shares · 2,908 followers View post →

Dwight Mannsburden

@DwightMansburdn · X

RT @AlexBerenson: Guess Dan Barouch doesn't understand "IgG4 nonsense" either. From his new paper: "mRNA immunizations may lead to IgG4 re…

Mar 21, 2024 · 14 shares · 724 followers View post →

1GolfPro23

@1golfpro23 · X

RT @AlexBerenson: Guess Dan Barouch doesn't understand "IgG4 nonsense" either. From his new paper: "mRNA immunizations may lead to IgG4 re…

Mar 21, 2024 · 14 shares · 367 followers View post →

Joanne Sienko Ott

@jsott7 · X

RT @AlexBerenson: Guess Dan Barouch doesn't understand "IgG4 nonsense" either. From his new paper: "mRNA immunizations may lead to IgG4 re…

Mar 21, 2024 · 14 shares · 1,160 followers View post →

Andreas K

@Andreas_Koutr · X

@Debunk_the_Funk Is there anything contradictory in these statements..? https://t.co/SaEFsyKfyo @Jikkyleaks https://t.co/1zFPTvSDcd

Mar 21, 2024 · 2 likes · 82 followers View post →

John Laughlin

@John242Ti · X

RT @AlexBerenson: Guess Dan Barouch doesn't understand "IgG4 nonsense" either. From his new paper: "mRNA immunizations may lead to IgG4 re…

Mar 21, 2024 · 14 shares · 656 followers View post →

Stephen Duncan Nutrition

@sduncanhealth · X

@Mr_Magoo5 @RotundC @ShaneAKAProp @mcfunny @BB0941167867205 @Veeteejay1 @ProfDuckDuckGo @trillionofcells @krebiozen @demonbirtherx3 @1_TMF_ @ASchifty @Questio31810600 @FUDyou2 @RN_MSN_Snark @AnnLove4All @Arkout3 @whodisdontcare @LordButters22 @WendyOrent @CaryDavid722 @TonyBaduy @bjurrows @TheFrankmanMN @Scary7Dr @TakethatCt @crabb_vicki @AphasiaAnomic @shinko_hadoken @Pouldeau61 @runhack @cappsie @raoulduke49 @taurusg333 @doritmi @Kathmarval @Danny459673 @DaveBla81093404 @MsTrixter @Hurriquake @MONTMAN9500 @StuWizzle @Golfergirl2018 @dann58638436 @encyclopath @Fornowago @Catheri49917567 @RadioColor @tonymac5 @groin_hammer https://t.co/1HZjQMw07k

Mar 1, 2024 · 2 likes · 3,376 followers View post →

Karol Johnson

@JohnsonKarol · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCWvgS

Feb 29, 2024 · 4 shares · 1,175 followers View post →

Ana LytiQa ❤️

@WakeDuhFuhCup1 · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCWvgS

Feb 29, 2024 · 4 shares · 1,539 followers View post →

CELTIC LIBERATION BRIGADE

@TurloughMor12 · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCWvgS

Feb 29, 2024 · 4 shares · 94 followers View post →

Ian Parkins

@parkins_ian · X

RT @CartlandDavid: Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCWvgS

Feb 29, 2024 · 4 shares · 1,035 followers View post →

Dr Dave Cartland BMedSc MBChB Ex-MRCGP

@CartlandDavid · X

Waning immunity and IgG4 responses following bivalent mRNA boosting | Science Advances https://t.co/R6lzBCWvgS

Feb 29, 2024 · 7 likes · 4 shares · 304,907 followers View post →

Thelonevirologist

@thelonevirologist.bsky.social · Bluesky

Waning immunity and IgG4 responses following bivalent mRNA boosting www.science.org/doi/10.1126/...

Feb 26, 2024 View post →

Waning immunity and IgG4 responses following bivalent mRNA boosting.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

2024 Insights on IgG4 Antibodies Post-mRNA COVID-19 Vaccination

COVID Prevention Insights and Vaccine Efficacy Updates