A l'avenir, on traitera peut être de façon plus ciblée des manifestations invalidantes qu'un ensemble de symptômes comme on le fait aujourd'hui. Par exemple, traiter l'irritabilité spécifiquement (et pas seulement le #TDAH). Cet essai l'illustre. https://t.co/S5DCqGmMET
Neural Responses to Intranasal Oxytocin in Youths With Severe Irritability.
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Feb 2024 – Aug 2024Where it's discussed
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X / Twitter17 posts
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YouTube2 videos
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Bluesky1 posts
AI synopsis
What people are saying
The overall discussions demonstrate strong support and intrigue, with phrases like 'promising clinical results' and detailed mentions of decreased activity in brain regions like the dorsomedial prefrontal cortex and posterior cingulate cortex. The tone's combination of scientific detail and optimistic outlook reflects a balanced yet impactful discussion of the study's potential implications for future treatments.
Most discussions support the positive findings of the study, highlighting improvements in irritability and neural changes attributed to intranasal oxytocin.
The posts indicate moderate interest, with many referencing clinical advances and neuroimaging results, though some focus on broader implications.
Several discussions reference specific results, such as decreased brain activity in emotion-related regions and clinical ratings, showing a fair level of engagement.
The discussions suggest these findings may influence clinical approaches to irritability in youth, emphasizing potential therapeutic benefits and the importance of further research.
Abstract in brief
- The study examined how intranasal oxytocin affects brain activity and symptoms in youths with severe irritability related to disruptive mood and behavior disorders, using clinical ratings and brain scans before and after treatment.
- Youths who received oxytocin showed greater improvements in irritability and global severity ratings, along with decreased brain activity in emotion-related areas like the dorsomedial prefrontal cortex and posterior cingulate cortex, which was linked to clinical improvements.
- The findings suggest that intranasal oxytocin may modify brain responses involved in emotion processing in irritable youths, potentially leading to reductions in irritability symptoms, although more research is needed for conclusive results.
Top posts
Most liked on X and BlueskyA new RCT finds children with severe irritability improved after 3 weeks of daily intranasal oxytocin, an improvement correlated with decreased responsiveness in dorsomedial prefrontal cortex and posterior cingulate cortex. @APA_Publishing https://t.co/nI28h0PRDJ https://t.co/nYLkG7sdbI
Neural Responses to Intranasal Oxytocin in Youths With Severe Irritability | American Journal of Psychiatry https://t.co/ZcfgNQ7rmJ
Promising clinical results and neuroimaging findings seen in a double-blind trial of intranasal oxytocin for irritability in youths. https://t.co/Nfi18dRzW4 https://t.co/vLONMxCUUx
New #podcast episode! Dr. Soonjo Hwang (University of Nebraska Medical Center) joins AJP Audio to discuss the response to intranasally-administered oxytocin in youths with severe irritability. https://t.co/whWu1sK3Uh https://t.co/jeCHy2JJ00
OL study: Youths who received oxytocin showed > improvement in CGI-S and CGI-I ratings for irritability vs. those who received placebo. fMRI BOLD responses to emotional stimuli in the DMPFC and posterior CC were reduced with oxytocin https://t.co/Ulpy4qHyEd
All mentions
Neural Impact of Intranasal Oxytocin on Youths with Severe Irritability
American Journal of Psychiatry Deputy Editor Daniel S Pine MD discusses research on how intranasal oxytocin influences brain activity and symptoms in youths with severe irritability, showing potential for emotion…
Impact of Intranasal Oxytocin on Brain Responses in Irritable Youths
The study examined how intranasal oxytocin affects brain activity and symptoms in youths with severe irritability related to disruptive mood and behavior disorders, using clinical ratings and brain scans before and…
Oxitocina intranasal en jóvenes con irritabilidad https://t.co/Y2SBJCeYQM
Neural Responses to Intranasal Oxytocin in Youths With Severe Irritability | American Journal of Psychiatry https://ajp.psychiatryonline.org/doi/10.1176/appi.ajp.20230174?utm_campaign=journalupdate&utm_source=email&utm_medium=textlink&utm_content=ajp
Neural Responses to Intranasal Oxytocin in Youths With Severe Irritability | American Journal of Psychiatry https://t.co/ZcfgNQ7rmJ
New on https://t.co/8pxKdRDxAR | Neural Responses to Intranasal Oxytocin in Youths With Severe Irritability | https://t.co/wH7jbvJxYZ https://t.co/oSX5PVVCVN
New on https://t.co/8pxKdRE5qp | April 2024: Neural Responses to Intranasal Oxytocin in Youths With Severe Irritability | https://t.co/Ldbzpj2851 https://t.co/KqjEDx2MhC
Neural Responses to Intranasal Oxytocin in Youths With Severe Irritability | American Journal of Psychiatry https://t.co/gVxtgOgI2D
Neural Responses to Intranasal Oxytocin in Youths With Severe Irritability Soonjo Hwang, M.D., et al. https://t.co/Lnxr9DyhZ6
AJP Deputy Editor Danny Pine highlights two articles from the April 2024 issue. https://t.co/rVaA2Whuoj
RT @YannLe_Strat: A l'avenir, on traitera peut être de façon plus ciblée des manifestations invalidantes qu'un ensemble de symptômes comme…
RT @YannLe_Strat: A l'avenir, on traitera peut être de façon plus ciblée des manifestations invalidantes qu'un ensemble de symptômes comme…
RT @YannLe_Strat: A l'avenir, on traitera peut être de façon plus ciblée des manifestations invalidantes qu'un ensemble de symptômes comme…
A l'avenir, on traitera peut être de façon plus ciblée des manifestations invalidantes qu'un ensemble de symptômes comme on le fait aujourd'hui. Par exemple, traiter l'irritabilité spécifiquement (et pas seulement le #TDAH). Cet essai l'illustre. https://t.co/S5DCqGmMET
New #podcast episode! Dr. Soonjo Hwang (University of Nebraska Medical Center) joins AJP Audio to discuss the response to intranasally-administered oxytocin in youths with severe irritability. https://t.co/whWu1sK3Uh https://t.co/jeCHy2JJ00
OL study: Youths who received oxytocin showed > improvement in CGI-S and CGI-I ratings for irritability vs. those who received placebo. fMRI BOLD responses to emotional stimuli in the DMPFC and posterior CC were reduced with oxytocin https://t.co/Ulpy4qHyEd
In an AJP Editorial, Argyris Stringaris @ucl @uoaofficial and Jamilah Silver @stonybrooku commend the authors of an RCT examining neural responses to intranasal oxytocin in youths with severe irritability. https://t.co/WmKW0z89Jc https://t.co/KZWUJTn8uI
RT @PsychopathyIs: A new RCT finds children with severe irritability improved after 3 weeks of daily intranasal oxytocin, an improvement co…
A new RCT finds children with severe irritability improved after 3 weeks of daily intranasal oxytocin, an improvement correlated with decreased responsiveness in dorsomedial prefrontal cortex and posterior cingulate cortex. @APA_Publishing https://t.co/nI28h0PRDJ https://t.co/nYLkG7sdbI
Promising clinical results and neuroimaging findings seen in a double-blind trial of intranasal oxytocin for irritability in youths. https://t.co/Nfi18dRzW4 https://t.co/vLONMxCUUx
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