Nat Aging May 2024 PMID 38609524

A conserved complex lipid signature marks human muscle aging and responds to short-term exercise.

Georges E Janssens, Marte Molenaars, Katharina Herzog, Lotte Grevendonk, Carlijn M E Remie, Martin A T Vervaart, Hyung L Elfrink, Eric J M Wever, Bauke V Schomakers, Simone W Denis, Hans R Waterham, Mia L Pras-Raves, Michel van Weeghel, Antoine H C van Kampen, Alessandra Tammaro

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Mentions

80
Peak: 11 in Apr 2024
across 6 sources since Apr 2024

Extended reach

247,609
potential audience

Total likes

1,274

Video views

73,761

Mentions per month

Apr 2024 – Dec 2024

Where it's discussed

  • News58 articles
  • X / Twitter13 posts
  • Blogs3 articles
  • YouTube2 videos
  • Facebook2 posts
  • Reddit2 posts

AI synopsis

What people are saying

Several discussions highlight the significance of lipid changes during aging and the positive influence of exercise, using phrases like 'reduces BMP levels' and 'markers of muscle aging.' The tone reflects curiosity and appreciation for how these findings could impact health, with detailed mentions of lipid types and biological responses, demonstrating an engaged audience that sees potential for meaningful advances in aging research.

AgreementModerate agreement

Most discussions acknowledge the study’s findings, especially regarding lipid changes with aging and exercise effects, showing general support.

InterestHigh interest

Participants are highly interested, shown by their enthusiasm and focus on the biological implications and potential applications.

EngagementModerate engagement

Posts involve specific references to the lipid types, animal and human data, and potential health impacts, indicating a moderate level of detailed engagement.

ImpactModerate impact

Discussions recognize the study’s importance for aging research and possible influence on health strategies, though some comments remain speculative.

Abstract in brief

  • Research on mice indicates that complex lipids like phospholipids are linked to longevity, but consistent changes related to aging and interventions are still unclear.
  • A study profiled over 1,200 unique lipids across different tissues and found significant accumulation of bis(monoacylglycero)phosphate (BMP) as mice age.
  • In humans, a similar BMP increase was observed in muscle tissues of older adults, and engaging in regular exercise helped reduce BMP levels in postmenopausal women, suggesting that lipid biology plays a crucial role in aging and can be influenced by health behaviors.

Top posts

Most liked on X and Bluesky
Nature Aging
@NatureAging · X

Online now! A new study by @rhhoutkooper and coworkers describes lipids that change with age. Bis(monoacylglycerol)phosphate accumulates in older mice and humans, and reduces upon exercise in female research participants. (https://t.co/7isfnFnwNY) https://t.co/X4TMLbh5dn

Apr 15, 2024 · 10 likes · 2 shares · 18,649 followers View post →
Sergey Minaev
@sminaev2015 · X

A conserved complex lipid signature marks human muscle aging and responds to short-term exercise | Nature Aging https://t.co/vBYNTJk0RE

Apr 13, 2024 · 6 likes · 2 shares · 31,480 followers View post →
Agingdoc
@agingdoc1 · X

A conserved complex lipid signature marks human muscle aging and responds to short-term exercise https://t.co/ywVacfJHFu

May 27, 2024 · 5 likes · 1 share · 41,365 followers View post →
Agingdoc
@agingdoc1 · X

A conserved complex lipid signature marks human muscle aging and responds to short-term exercise

Apr 14, 2024 · 4 likes · 41,365 followers View post →
Salva Iborra
@salva_iborra · X

A conserved complex lipid signature marks human muscle aging and responds to short-term exercise https://t.co/myUMdVuekq

Apr 17, 2024 · 2 likes · 3,888 followers View post →
Sergey Minaev
@sminaev2015 · X

RT @sminaev2015: A conserved complex lipid signature marks human muscle aging and responds to short-term exercise | Nature Aging https://t.…

Apr 14, 2024 · 2 shares · 31,480 followers View post →

All mentions

Mind Your Science!
@MindYourSci · X

RT @agingdoc1: A conserved complex lipid signature marks human muscle aging and responds to short-term exercise https://t.co/ywVacfJHFu

May 28, 2024 · 1 share · 133 followers View post →
Agingdoc
@agingdoc1 · X

A conserved complex lipid signature marks human muscle aging and responds to short-term exercise https://t.co/ywVacfJHFu

May 27, 2024 · 5 likes · 1 share · 41,365 followers View post →
HealthyBuilds
@JamesSw70043542 · X

A conserved complex lipid signature marks human muscle aging and responds to short-term exercise https://t.co/KwyIUjkwC5

Apr 22, 2024 · 16 followers View post →
axel
@Linda3311133 · X

A conserved complex lipid signature marks human muscle aging and responds to short-term exercise | Nature Aging https://t.co/NFGKWTqqFa

Apr 19, 2024 · 32 followers View post →
Salva Iborra
@salva_iborra · X

A conserved complex lipid signature marks human muscle aging and responds to short-term exercise https://t.co/myUMdVuekq

Apr 17, 2024 · 2 likes · 3,888 followers View post →
Riekelt Houtkooper
@rhhoutkooper · X

RT @NatureAging: Online now! A new study by @rhhoutkooper and coworkers describes lipids that change with age. Bis(monoacylglycerol)phospha…

Apr 15, 2024 · 2 shares · 1,663 followers View post →
YMED-X
@YmedX269 · X

RT @NatureAging: Online now! A new study by @rhhoutkooper and coworkers describes lipids that change with age. Bis(monoacylglycerol)phospha…

Apr 15, 2024 · 2 shares · 229 followers View post →
Nature Aging
@NatureAging · X

Online now! A new study by @rhhoutkooper and coworkers describes lipids that change with age. Bis(monoacylglycerol)phosphate accumulates in older mice and humans, and reduces upon exercise in female research participants. (https://t.co/7isfnFnwNY) https://t.co/X4TMLbh5dn

Apr 15, 2024 · 10 likes · 2 shares · 18,649 followers View post →
Sergey Minaev
@sminaev2015 · X

RT @sminaev2015: A conserved complex lipid signature marks human muscle aging and responds to short-term exercise | Nature Aging https://t.…

Apr 14, 2024 · 2 shares · 31,480 followers View post →
Agingdoc
@agingdoc1 · X

A conserved complex lipid signature marks human muscle aging and responds to short-term exercise

Apr 14, 2024 · 4 likes · 41,365 followers View post →
Saurabh
@svp7 · X

RT @sminaev2015: A conserved complex lipid signature marks human muscle aging and responds to short-term exercise | Nature Aging https://t.…

Apr 13, 2024 · 2 shares · 3,504 followers View post →
Aging Papers
@PapersAging · X

A conserved complex lipid signature marks human muscle aging and responds to short-term exercise https://t.co/OGz651bWP4

Apr 13, 2024 · 16 followers View post →
Sergey Minaev
@sminaev2015 · X

A conserved complex lipid signature marks human muscle aging and responds to short-term exercise | Nature Aging https://t.co/vBYNTJk0RE

Apr 13, 2024 · 6 likes · 2 shares · 31,480 followers View post →