Atrial Shunt Device Effects on Cardiac Structure and Function in Heart Failure With Preserved Ejection Fraction: The REDUCE LAP-HF II Randomized Clinical Trial.
Ravi B Patel, Frank E Silvestry, Jan Komtebedde, Scott D Solomon, Gerd Hasenfuß, Sheldon E Litwin, Barry A Borlaug, Matthew J Price, Rami Kawash, Scott L Hummel, Donald E Cutlip, Martin B Leon, Dirk J van Veldhuisen, Andreas J Rieth, Scott McKenzie
June 2024 JAMA CardiolSynopsis of Social media discussions
The discussions express strong support and curiosity about the research, with examples like 'reverse remodeling' and mentions of 'favorable effects' indicating perceived clinical importance. The tone is positive and recalls specific results, such as the lack of RV dysfunction over two years, reflecting moderate engagement and high perceived impact of the findings.
Agreement
Moderate agreementMost discussions support the positive effects of the atrial shunt device, emphasizing findings such as 'reverse remodeling' and 'favorable effects' from recent studies.
Interest
High level of interestThe discussions demonstrate high interest, with repeated references to specific research outcomes, clinical implications, and ongoing questions about long-term effects.
Engagement
Moderate level of engagementSeveral posts delve into detailed analysis, such as the mention of 'no change in RV systolic function' and 'long-term effects,' showing moderate physical and technical engagement.
Impact
Moderate level of impactParticipants seem to believe the research could influence future treatments for heart failure with preserved ejection fraction, indicated by phrases like 'favorable effects' and references to what the data mean for clinical practice.
Social Mentions
YouTube
2 Videos
3 Posts
10 Posts
News
56 Articles
Metrics
Video Views
1,847
Total Likes
22
Extended Reach
163,513
Social Features
71
Timeline: Posts about article
Top Social Media Posts
JAMA Cardiology
Over 2 years of follow-up, atrial shunting in patients with HFpEF and HFmrEF led to reverse remodeling of left-sided chambers and increases in volume of right-sided chambers but no change in RV systolic function compared with sham. https://t.co/qtdBf3VumJ https://t.co/BLpkoc2bAE
view full post
JAMA Cardiology
Interview with Sanjiv J. Shah, MD, author of "Atrial Shunt Device Effects on Cardiac Structure and Function in Heart Failure With Preserved Ejection Fraction: The REDUCE LAP-HF II Randomized Clinical Trial" hosted by James E. Udelson, MD. @HFpEF https://t.co/zKvgy0sfFd
view full post
JAMA Cardiology
Over 2 years of follow-up, atrial shunting in patients with HFpEF and HFmrEF led to reverse remodeling of left-sided chambers and increases in volume of right-sided chambers but no change in RV systolic function compared with sham. https://t.co/aEhCWnHlSi
view full post
Ahmed Bennis MD
Atrial Shunt Device Effects on Cardiac Structure and Function in Heart Failure With Preserved Ejection Fraction
The REDUCE LAP-HF II Randomized Clinical Trial
no evidence of RV dysfunction over the initial 2 years
https://t.co/GGOpZ0RXIv
view full post
Ahmed Bennis MD
Atrial Shunt Device Effects on Cardiac Structure and Function in Heart Failure With Preserved Ejection Fraction
The REDUCE LAP-HF II Randomized Clinical Trial
no evidence of RV dysfunction over the initial 2 years
https://t.co/GGOpZ0RXIv
view full post
Posts referencing the article
Effects of Atrial Shunt Device on Heart Function in Heart Failure Patients
The REDUCE LAP-HF II trial evaluated the impact of the Corvia Medical Inc IASD System II atrial shunt on cardiac structure and function in heart failure patients, showing potential benefits such as reduced ventricular volume and improved heart metrics.
May 8, 2024
306 views
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Congratulations to #TPCH's S. McKenzie for their contribution to the publication "Atrial Shunt Device Effects on Cardiac Structure and Function in Heart Failure With Preserved Ejection Fraction: The REDUCE LAP-HF II Randomized Clinical Trial" https://t.co/6STdkJpzr5
view full postJune 23, 2024
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JAMA Cardiology
@JAMACardio (Twitter)Over 2 years of follow-up, atrial shunting in patients with HFpEF and HFmrEF led to reverse remodeling of left-sided chambers and increases in volume of right-sided chambers but no change in RV systolic function compared with sham. https://t.co/aEhCWnHlSi
view full postJune 20, 2024
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Ahmed Bennis MD
@drbennisahmed (Twitter)Atrial Shunt Device Effects on Cardiac Structure and Function in Heart Failure With Preserved Ejection Fraction The REDUCE LAP-HF II Randomized Clinical Trial no evidence of RV dysfunction over the initial 2 years https://t.co/GGOpZ0RXIv
view full postJune 13, 2024
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Chidambara .ML.
@chidambara09 (Twitter)RT @corviamedical: What is the long-term effect of an #atrialshunt? Recently published data in @JAMACardio by @RBPatelMD shows favorable ef…
view full postMay 10, 2024
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Corvia Medical, Inc.
@corviamedical (Twitter)What is the long-term effect of an #atrialshunt? Recently published data in @JAMACardio by @RBPatelMD shows favorable effects of the Corvia Atrial Shunt on cardiac structure & function in #heartfailure patients. #HFpEF #cardiotwitter https://t.co/wMGwBUNxtc
view full postMay 10, 2024
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JAMA Cardiology
@JAMACardio (Twitter)Interview with Sanjiv J. Shah, MD, author of "Atrial Shunt Device Effects on Cardiac Structure and Function in Heart Failure With Preserved Ejection Fraction: The REDUCE LAP-HF II Randomized Clinical Trial" hosted by James E. Udelson, MD. @HFpEF https://t.co/zKvgy0sfFd
view full postApril 18, 2024
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Ahmed Bennis MD
@drbennisahmed (Twitter)Atrial Shunt Device Effects on Cardiac Structure and Function in Heart Failure With Preserved Ejection Fraction The REDUCE LAP-HF II Randomized Clinical Trial no evidence of RV dysfunction over the initial 2 years https://t.co/GGOpZ0RXIv
view full postApril 18, 2024
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Riccardo M. Inciardi, MD, PhD
@RInciardi (Twitter)RT @JAMACardio: Over 2 years of follow-up, atrial shunting in patients with HFpEF and HFmrEF led to reverse remodeling of left-sided chambe…
view full postApril 17, 2024
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Ravi Patel
@RBPatelMD (Twitter)RT @JAMACardio: Over 2 years of follow-up, atrial shunting in patients with HFpEF and HFmrEF led to reverse remodeling of left-sided chambe…
view full postApril 17, 2024
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JAMA Cardiology
@JAMACardio (Twitter)Over 2 years of follow-up, atrial shunting in patients with HFpEF and HFmrEF led to reverse remodeling of left-sided chambers and increases in volume of right-sided chambers but no change in RV systolic function compared with sham. https://t.co/qtdBf3VumJ https://t.co/BLpkoc2bAE
view full postApril 17, 2024
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Abstract Synopsis
- The REDUCE LAP-HF II trial analyzed the efficacy of the Corvia Medical Inc IASD System II atrial shunt in patients with heart failure, showing potential benefits for responders without underlying vascular or rhythm issues.
- The study involved randomizing participants to receive either the atrial shunt or a sham control, focusing on changes in heart function measured via echocardiograms over 24 months.
- Results indicated that the shunt significantly reduced left ventricular volume and improved heart function metrics compared to sham controls, with a high rate of successful shunt placements among participants.
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