Could GLP-1 Receptor Agonists Like Semaglutide Treat Addiction, Alzheimer Disease, and Other Conditions?

Rita Rubin

May 2024 JAMA

Synopsis of Social media discussions

The collective discussions demonstrate strong enthusiasm and interest, with many users citing studies from reputable journals like JAMA, and emphasizing the transformative potential of GLP-1 receptor agonists for conditions like addiction and Alzheimer's. The tone and language indicate a belief in their future impact, discussion of ongoing research, and skepticism about exaggerated claims, reflecting both excitement and critical evaluation.

A
Agreement
 Strong agreement

Most discussions support the potential of GLP-1 receptor agonists in treating various conditions, emphasizing the promising nature of the research.

I
Interest
 High level of interest

Posts exhibit high curiosity, highlighting ongoing clinical trials and potential new uses for these drugs.

E
Engagement
 High engagement

Many comments reference specific studies, cite articles, and discuss implications, showing deep involvement.

I
Impact
 High level of impact

The general tone suggests these findings could significantly influence medical practices and drug repurposing debates.

Social Mentions

YouTube

8 Videos

Facebook

6 Posts

Twitter

163 Posts

Blogs

3 Articles

News

33 Articles

Metrics

Video Views

3,040,190

Total Likes

144,312

Extended Reach

5,204,119

Social Features

213

Timeline: Posts about article

Top Social Media Posts

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  • Brian Rifkin, MD
    @brian_rifkin (Twitter)

    @kidney_boy Could work? They are looking into it for all addictions, not just overeating https://t.co/G2QoUOcj2Z
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    October 22, 2025

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  • Muhammad
    @MuhammadMDFAAFP (Twitter)

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    December 4, 2024

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  • MWR DBM
    @mwr_dbm (Twitter)

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    @kolla_bharathi (Twitter)

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    May 23, 2024

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  • ForensicPsyMD
    @ForensicPsyMD (Twitter)

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    May 23, 2024

  • د محمد الحجيلي
    @dr_hojele (Twitter)

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    @yousefM6 (Twitter)

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    @Dr_Lama_Amer (Twitter)

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    May 22, 2024

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  • Scott Isaacs
    @scottisaacsmd (Twitter)

    GLP-1 receptor agonists like #semaglutide show promise in treating addiction, Alzheimer's, and more. Clinical trials are underway to explore their potential benefits. #GLP1receptoragonists #medicalresearch https://t.co/mLm27atd0E https://t.co/BMMzc7JPVx
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  • Joaquin Cabezas
    @JCabezasGlez (Twitter)

    RT @DrJavierCrespo: Los aGLP1, ¿valen para todo? 1⃣Control DMII 2⃣ < Peso 3⃣ < riesgo vascular 4⃣< morbilidad IC con FE conservada 5⃣¿<depe…
    view full post

    April 20, 2024

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  • ObesitySEEN
    @ObesitySeen (Twitter)

    RT @mdballesteros: Blockbuster Obesity Drugs Have Potential New Uses. Could GLP-1 Receptor Agonists like Semaglutide Treat Addiction, Alzhe…
    view full post

    April 20, 2024

    5

  • The Innovation | Medicine
    @Innov_Medicine (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
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    April 20, 2024

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  • NURIA VILARRASA
    @NURIAVILARRASA2 (Twitter)

    RT @mdballesteros: Blockbuster Obesity Drugs Have Potential New Uses. Could GLP-1 Receptor Agonists like Semaglutide Treat Addiction, Alzhe…
    view full post

    April 20, 2024

    5

  • ボブにゃんVRC
    @zapabob_ouj (Twitter)

    https://t.co/217xEuJDMB
    view full post

    April 20, 2024

  • Centre de Neurologie Cognitive
    @CNC_Alzheimer (Twitter)

    Could GLP-1 Receptor Agonists like Semaglutide Treat Addiction, Alzheimer Disease, and Other Conditions? | Diabetes | JAMA | JAMA Network https://t.co/bydCxTJcEI
    view full post

    April 20, 2024

  • Círculo Escéptico
    @cescept (Twitter)

    RT @vbaosv: Creo que habrá que vigilar con lupa las "evidencias" que sustenten que estos medicamentos valgan para "casi todo" Blockbuster…
    view full post

    April 20, 2024

    2

  • Ahmed Abdelaziz, MD
    @AbdelazizMD1 (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
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    April 20, 2024

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  • @RitaRubin.bsky.social
    @RitaRubin (Twitter)

    RT @pash22: Could GLP-1 Receptor Agonists like Semaglutide Treat Addiction, Alzheimer Disease, and Other Conditions? https://t.co/pJwHlSIJX…
    view full post

    April 20, 2024

    1

  • Christopher Sylvain
    @ChrisSylvain (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 20, 2024

    77

  • Cristobal Morales
    @CristobMorales (Twitter)

    https://t.co/oScJQCJrMo Could GLP-1 Receptor Agonists like Semaglutide Treat Addiction, Alzheimer Disease, and Other Conditions? @JAMANetwork
    view full post

    April 20, 2024

    3

  • Ichor Clinical
    @IchorClinical (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
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    April 20, 2024

    77

  • PostX #UniteToFight2024
    @TeamPostX (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 20, 2024

    77

  • Zdenek Vrozina
    @ZdenekVrozina (Twitter)

    Mohli by agonisté receptoru GLP-1, jako je semaglutid, léčit závislost, Alzheimerovu chorobu a další nemoci? | | JAMA https://t.co/5WDxKHDbKo
    view full post

    April 20, 2024

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  • nike
    @wot_mikey (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 20, 2024

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  • Cristina Tejera
    @cristinatejerap (Twitter)

    RT @mdballesteros: Blockbuster Obesity Drugs Have Potential New Uses. Could GLP-1 Receptor Agonists like Semaglutide Treat Addiction, Alzhe…
    view full post

    April 20, 2024

    5

  • Antonio Serrano
    @DrSerranoLeon (Twitter)

    RT @mdballesteros: Blockbuster Obesity Drugs Have Potential New Uses. Could GLP-1 Receptor Agonists like Semaglutide Treat Addiction, Alzhe…
    view full post

    April 20, 2024

    5

  • María Ballesteros
    @mdballesteros (Twitter)

    Blockbuster Obesity Drugs Have Potential New Uses. Could GLP-1 Receptor Agonists like Semaglutide Treat Addiction, Alzheimer Disease, and Other Conditions? https://t.co/pJeU0SRjtJ
    view full post

    April 20, 2024

    9

    5

  • PpandeloF1
    @PpandeloF (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 20, 2024

    77

  • hasan alshakere.
    @hasanalshakeere (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 20, 2024

    77

  • Polar Bear
    @chaiwat_non (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 20, 2024

    77

  • Ash Paul
    @pash22 (Twitter)

    Could GLP-1 Receptor Agonists like Semaglutide Treat Addiction, Alzheimer Disease, and Other Conditions? https://t.co/pJwHlSIJXB via @RitaRubin
    view full post

    April 20, 2024

    1

    1

  • Dre Julie-F Garand OD
    @garand_f (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 20, 2024

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  • özkan akhan
    @ozkanakhan (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 20, 2024

    77

  • sss
    @sakipo_ (Twitter)

    RT @ksktkht8: GLP-1受容体アゴニストの依存症、アルツハイマー病、パーキンソン病における治療薬としての可能性について JAMA 2024 https://t.co/W6tN4yLk2Q
    view full post

    April 20, 2024

    5

  • Elena del Olmo
    @eledelolmo (Twitter)

    RT @DrJavierCrespo: Los aGLP1, ¿valen para todo? 1⃣Control DMII 2⃣ < Peso 3⃣ < riesgo vascular 4⃣< morbilidad IC con FE conservada 5⃣¿<depe…
    view full post

    April 20, 2024

    7

  • Vicente Baos
    @vbaosv (Twitter)

    Creo que habrá que vigilar con lupa las "evidencias" que sustenten que estos medicamentos valgan para "casi todo" Blockbuster Obesity Drugs Have Potential New Uses https://t.co/KC2PhCZd8r
    view full post

    April 20, 2024

    9

    2

  • Javier Carrera
    @Javier_CarreraH (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 20, 2024

    77

  • Jazz
    @jazz999143 (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 20, 2024

    77

  • Anssi H. Manninen | Mass Balance Man
    @KingManninen (Twitter)

    @JAMA_current "Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions?" No. Such claims are, of course, pure marketing. The same strategy has been in use from Day 1: pharmaceutical companies hire "researchers" to write fake articles.
    view full post

    April 20, 2024

  • Nat’s Pancreas 404
    @1derfultype (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 20, 2024

    77

  • Colorful MD Phd
    @FanYang38636272 (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 20, 2024

    77

  • Silvia Quadrelli
    @SilviaQuadrell2 (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 20, 2024

    77

  • Alasse
    @alassesingollo (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 20, 2024

    77

  • sabeehah
    @sabeehahv (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 20, 2024

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  • Andrew J Sauer MD
    @AndrewJSauer (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 20, 2024

    77

  • syawal™ シ
    @syawal (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 20, 2024

    77

  • Ezeonufo Chukwunonso
    @Ezeonufo (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 19, 2024

    77

  • Ryuhei So
    @RyuheiSo (Twitter)

    RT @ksktkht8: GLP-1受容体アゴニストの依存症、アルツハイマー病、パーキンソン病における治療薬としての可能性について JAMA 2024 https://t.co/W6tN4yLk2Q
    view full post

    April 19, 2024

    5

  • IMPUNIDAD CERO
    @ARAA1981 (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 19, 2024

    77

  • thmonk
    @thmonk_pf (Twitter)

    RT @ksktkht8: GLP-1受容体アゴニストの依存症、アルツハイマー病、パーキンソン病における治療薬としての可能性について JAMA 2024 https://t.co/W6tN4yLk2Q
    view full post

    April 19, 2024

    5

  • John Maley
    @weejockmaley (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 19, 2024

    77

  • KSK@neuropsychiatry
    @ksktkht8 (Twitter)

    GLP-1受容体アゴニストの依存症、アルツハイマー病、パーキンソン病における治療薬としての可能性について JAMA 2024 https://t.co/W6tN4yLk2Q
    view full post

    April 19, 2024

    17

    5

  • ana
    @anamareyesp (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 19, 2024

    77

  • Stavra Xanthakos
    @DrStavra (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 19, 2024

    77

  • dan majerczyk
    @DanMajerczyk (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 19, 2024

    77

  • Servicio de Geriatría del INCMNSZ
    @INCMNSZ_Geria (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 19, 2024

    77

  • Ryan Flinn
    @RS_Flinn (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 19, 2024

    77

  • Nanacatl AS
    @wolfkid_fungus (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 19, 2024

    77

  • Manoj Mayogi Mishra
    @mayogisense (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 19, 2024

    77

  • Ed Márquez
    @dremarquezr (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 19, 2024

    77

  • Philippe Froguel
    @philippefroguel (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 19, 2024

    77

  • DrAlexandra
    @DrAlexaGastro (Twitter)

    RT @DrJavierCrespo: Los aGLP1, ¿valen para todo? 1⃣Control DMII 2⃣ < Peso 3⃣ < riesgo vascular 4⃣< morbilidad IC con FE conservada 5⃣¿<depe…
    view full post

    April 19, 2024

    7

  • Denis Donovan, MD
    @NYYanks2462 (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 19, 2024

    77

  • Luis diaz
    @CsarRui86346276 (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 19, 2024

    77

  • Glen Beeby
    @GlenBeebyNews (Twitter)

    RT @DrBenjaminHorne: Blockbuster Obesity Drugs Have Potential New Uses @JAMA_current https://t.co/quEUx2J9NU
    view full post

    April 19, 2024

    2

  • M.D. Alex L.
    @dr_alex_lara (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 19, 2024

    77

  • cesarnavarro
    @davenavarrop (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 19, 2024

    77

  • David
    @vadeansonder (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 19, 2024

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  • Juan Ignacio Arano
    @AranoIgnacio (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 19, 2024

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  • Marcia S Newman
    @marciasgreen (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 19, 2024

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  • BryanRoth
    @zenbrainest (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 19, 2024

    77

  • Lulu
    @imlulual (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 19, 2024

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  • @REBEGE (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 19, 2024

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  • T.kimura
    @jjcrazydiamond (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 19, 2024

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  • Luke Nakaji/中島 振一郎@バルサと島巡りと猫と精神医療
    @Luke_629 (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 19, 2024

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  • Javier Crespo
    @DrJavierCrespo (Twitter)

    Los aGLP1, ¿valen para todo? 1⃣Control DMII 2⃣ < Peso 3⃣ < riesgo vascular 4⃣< morbilidad IC con FE conservada 5⃣¿<dependencia alcohol / tabaco / coca 6⃣ Efecto neuroprotector y < Parkinson https://t.co/526hXSK9hp
    view full post

    April 19, 2024

    12

    7

  • Alberto Dias Filho
    @albertodiasf (Twitter)

    Blockbuster Obesity Drugs Have Potential New Uses https://t.co/NlZhpZrIeI
    view full post

    April 19, 2024

  • 村田悠典 | 医学論文AI総合サイト MVidEra | 論文全文検索AI 開発
    @yusuke_m_MU (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
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    April 19, 2024

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  • Ying-Chu Chen
    @coachstevetw (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 19, 2024

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  • Bertrand Delsuc
    @BertrandBio (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 19, 2024

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  • Overlizard
    @Aitch_El (Twitter)

    RT @JAMA_current: Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human…
    view full post

    April 19, 2024

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  • JAMA
    @JAMA_current (Twitter)

    Could GLP-1 receptor agonists like semaglutide treat addiction, Alzheimer disease, and other conditions? Animal and human studies have uncovered a host of possible uses for drugs that stimulate the ubiquitous GLP-1 receptors. https://t.co/Gfp1ougjPT https://t.co/zg5E3TRG9B
    view full post

    April 19, 2024

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  • John P Erwin III MD MBA MACC (#BigPoppy )
    @HeartOTXHeartMD (Twitter)

    RT @DrBenjaminHorne: Blockbuster Obesity Drugs Have Potential New Uses @JAMA_current https://t.co/quEUx2J9NU
    view full post

    April 19, 2024

    2

  • STIGMABASE
    @stigmabase (Twitter)

    {Fighting Stigma} Could GLP-1 Receptor Agonists like Semaglutide Treat Addiction, Alzheimer Disease, and ...: Yammine, an associate professor in the department of psychiatry and behavioral sciences at UTHealth Houston, found some animal studies… https://t.co/fhiL1BNt2T
    view full post

    April 19, 2024

  • Benjamin Horne
    @DrBenjaminHorne (Twitter)

    Blockbuster Obesity Drugs Have Potential New Uses @JAMA_current https://t.co/quEUx2J9NU
    view full post

    April 19, 2024

    5

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  • Carlos del Rio
    @CarlosdelRio7 (Twitter)

    Blockbuster Obesity Drugs Have Potential New Uses https://t.co/nEVLKbzRDt @JAMA_current
    view full post

    April 19, 2024

    7

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  • @RitaRubin.bsky.social
    @RitaRubin (Twitter)

    My latest for @JAMA_current: Blockbuster Obesity Drugs Have Potential New Uses https://t.co/UUOmZMH2g3
    view full post

    April 19, 2024

Abstract Synopsis

  • GLP-1 receptor agonists like semaglutide are primarily used for diabetes and weight loss, but recent research suggests they might also help treat addiction, Alzheimer's disease, and other conditions.
  • These drugs work by activating GLP-1 receptors in the brain, which could influence appetite control, memory, and addictive behaviors.
  • While promising, more studies are needed to understand how effective these medications are for these new uses and whether they can be safely used beyond their current indications.