Designer peptide-DNA cytoskeletons regulate the function of synthetic cells.

Margaret L Daly, Kengo Nishi, Stephen J Klawa, Kameryn Y Hinton, Yuan Gao, Ronit Freeman

August 2024 Nat Chem

Synopsis of Social media discussions

Discussions emphasize the innovative design of peptide-DNA crosslinkers and their applications in repairing tissues or delivering drugs precisely, reflecting excitement and recognition of the research’s significance. The tone highlights the potential for revolutionary applications in medicine and synthetic biology, supported by mentions of reconfigurable structures and dynamic control, which underscore the perceived high impact and interest.

A
Agreement
 Moderate agreement

Most discussions recognize the significance of the research, noting potential applications in tissue repair and targeted drug delivery.

I
Interest
 High level of interest

The topic generates high interest, especially among those excited about advancements in synthetic biology and nanotechnology.

E
Engagement
 Moderate level of engagement

Participants reference the mechanisms and potential uses of the peptide-DNA cytoskeletons, indicating active engagement.

I
Impact
 High level of impact

Many perceive the research as highly impactful, particularly in medical and biotechnological fields, emphasizing its transformative potential.

Social Mentions

YouTube

2 Videos

Bluesky

2 Posts

Facebook

4 Posts

Twitter

2 Posts

Blogs

6 Articles

News

45 Articles

Metrics

Video Views

32,997

Total Likes

265

Extended Reach

35,834

Social Features

61

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

First Programmable Artificial Cells Enable Dynamic Synthetic Cell Control

First Programmable Artificial Cells Enable Dynamic Synthetic Cell Control

Scientists at UNC-Chapel Hill have developed reconfigurable synthetic cells with programmable DNA and peptide-based cytoskeletons. These stable, adaptable artificial cells can respond to environmental stimuli, opening new possibilities in medicine and materials science.

uncover reality

July 7, 2025

32,975 views

Innovative Approach to Creating Functional Artificial Cells

Innovative Approach to Creating Functional Artificial Cells

Researchers develop reconfigurable peptide-DNA cytoskeletons inspired by actin-binding proteins to control synthetic cell structure and function, enabling dynamic shape changes and adjustable mechanical properties.

Merkarenicus

April 28, 2024

23 views

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    @Metamedicsmx (Twitter)


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    June 23, 2025

  • B i y o t e k n o l o j i
    @Biyoteknolojitr (Twitter)

    Yapay hücreler, hasar görmüş dokuları onarmak veya ilaçları doğrudan hastalıklı bölgelere taşımak için kullanılabilir. https://t.co/WveroNDTU8
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    May 24, 2024

  • Astrobiology
    @astrobiology.bsky.social (Bluesky)

    Designer peptide–DNA Cytoskeletons Regulate The Function Of Synthetic Cells astrobiology.com/2024/04/desi... #astrobiology #nanotechnology #Synbio #genomics
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    April 29, 2024

    1

  • Erik Hom
    @erikfyhom.bsky.social (Bluesky)

    Designer peptide–DNA cytoskeletons regulate the function of synthetic cells https://www.nature.com/articles/s41557-024-01509-w
    view full post

    April 24, 2024

Abstract Synopsis

  • The researchers designed peptide-DNA crosslinkers inspired by actin-binding proteins to create a reconfigurable cytoskeleton for synthetic cells, enabling dynamic control over their structure and mechanical properties.
  • These peptide-DNA structures form tactoid-shaped bundles with adjustable shapes and mechanics, which can be localized to specific areas within synthetic cell droplets, influencing how molecules diffuse inside.
  • The system allows for reversible attachment and release of payloads, as well as shape changes of the synthetic cells triggered by heat, making it a versatile platform for building customizable artificial cells.]