September 2024 PMID 38848543

The Influence of Dietary Isothiocyanates on the Effectiveness of Mitomycin C and Bacillus Calmette-Guérin in Treating Nonmuscle-Invasive Bladder Cancer.

Marilyn L Kwan, Zinian Wang, Reina Haque, Valerie S Lee, Janise M Roh, Isaac J Ergas, Kimberly L Cannavale, Rachel Pratt, Maciej Goniewicz, Ronald K Loo, David S Aaronson, Charles P Quesenberry, Yuesheng Zhang, Christine B Ambrosone, Lawrence H Kushi

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Mentions

Peak: 1 in Aug 2024

across 3 sources since Aug 2024

Extended reach

93,780

potential audience

Total likes

2,492

Video views

91,106

Mentions per month

Aug 2024 – Jun 2025

Where it's discussed

YouTube2 videos
News2 articles
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AI synopsis

What people are saying

The discussions reflect a positive attitude towards the findings, with comments like 'diet could be a game changer' indicating enthusiasm, while others question how these dietary factors will translate into clinical practice. The tone combines curiosity, cautious optimism, and scientific interest, emphasizing the potential importance of diet in cancer treatment scenarios.

AgreementModerate agreement

Most discussions agree that the study highlights the potential role of diet, particularly cruciferous vegetables, in improving bladder cancer treatments.

InterestHigh interest

Posts demonstrate high interest, with many expressing curiosity about integrating dietary changes and examining the study’s broader implications.

EngagementModerate engagement

Comments often delve into details about the research methods and possible practical applications, showing moderate depth of discussion.

ImpactModerate impact

While some acknowledge the significance, many regard it as promising but preliminary, indicating a moderate perceived impact.

Abstract in brief

Nonmuscle-invasive bladder cancer (NMIBC) is frequently treated with mitomycin C (MMC) and bacillus Calmette-Guérin (BCG), but high recurrence rates remain a challenge.
Research suggests that dietary isothiocyanates from cruciferous vegetables may enhance the effectiveness of these treatments by boosting enzyme metabolism and immune responses.
In a study with 1158 NMIBC patients, those on BCG who consumed more than 2.4 servings of raw cruciferous vegetables per month showed significantly lower risks of both first and multiple recurrences, indicating a potential benefit of diet in managing this cancer.

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Amy Comander MD, DipABLM

@DrAmyComander · X

The Influence of Dietary Isothiocyanates on the Effectiveness of Mitomycin C and Bacillus Calmette-Guérin in Treating Nonmuscle-Invasive Bladder Cancer | Journal of Urology https://t.co/J7XcIaUONo~

Aug 19, 2024 · 2,655 followers View post →

Raw Cruciferous Vegetables Might Reduce Risk of NMIBC ...

News

doi:10.1097/JU.0000000000004070. Share this article. facebook share Share on Facebook · twitter share Share on Twitter · linkedin share Share on ...

Aug 22, 2024 View →

Raw Cruciferous Vegetables Might Reduce NMIBC Recurrence Risk ...