Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién publicado, para disminuir la incidencia de hipoxemia y paro peri-intubación DOI:10.1056/NEJMoa2313680 Aplicando la mejor evidencia inmediatamente #UCIHGSJR https://t.co/LXSjdjnonD
Noninvasive Ventilation for Preoxygenation during Emergency Intubation.
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Jun 2024 – Aug 2025Where it's discussed
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[- **The discussions surrounding the videos primarily focus on the effectiveness of noninvasive ventilation (NIV) for preoxygenation during emergency intubation, as compared to traditional oxygen mask methods. Contributors highlight key findings from studies, particularly the PREOXI trial, which demonstrate significant reductions in hypoxemia and cardiac arrest incidents with NIV.** - **Several posts provide specific examples and summaries of the research, such as mentions of the PREOXI trial's findings, where hypoxemia rates were significantly lower with NIV (9.1% vs. 18.5%). Discussions emphasize the transformative potential of NIV for emergency medicine, using phrases like "game changer" and "must consider" to convey excitement and urgency about adopting this method. The tone varies between academic, acknowledging skepticism about changing established practices, and enthusiastic, celebrating new advancements in critical care.** - **These posts relate directly to the scientific publication by encapsulating its results and implications, reinforcing points made in the article regarding the comparative advantages of NIV over traditional oxygen masks for preoxygenation. They reflect on the study's population of critically ill adults and underline the findings concerning reduced hypoxemia and cardiac arrest, driving home the article's message about the relevance of adjusting emergency intubation practices in light of new evidence.**]
Abstract in brief
- In a study involving critically ill adults undergoing tracheal intubation, researchers compared preoxygenation methods: noninvasive ventilation versus oxygen mask.
- The findings revealed that hypoxemia occurred significantly less in the noninvasive-ventilation group (9.1%) compared to the oxygen-mask group (18.5%).
- Additionally, the incidence of cardiac arrest was lower with noninvasive ventilation (0.2%) compared to the oxygen-mask group (1.1%).
Top posts
Most liked on X and BlueskyGame changer論文! これだけの効果があるならpre-oxygenationにNPPVを使わない手はない! でも実際は手間すぎて必要な患者(肥満や低酸素血症など解剖学的/生理学的difficult airwayなど)に絞ってやることになりそうな。 NC全開+BVM(±PEEPバルブ)で大体はまかなえるか https://t.co/TeyJsqE0wd
In "Noninvasive ventilation for preoxygenation during emergency intubation," researchers randomized critically ill adults requiring tracheal intubation to receive preoxygenation with either BIPAP or an oxygen mask. Read the October 2024 SM&A summary: https://t.co/LYIIFeaegG https://t.co/xU1SNPIJ9W
重症患者の気管挿管での前酸素化はNIV(Bilevel PAP)?、それともマスク? NIV群の方が低酸素血症(SpO2<85%)が少ない(9.1% vs. 18.5%)という結果。 PREOXI trial https://t.co/Zh44Gq4ZwN
ERとICUでの重篤な成人患者1300人を対象にしたPREOXI試験、結果が明らかに! NIPPV vs マスクでのpre-oxygenation戦略を比較。 NIPPVは重篤なSpO2低下を防ぎ、心停止リスク減少(NNT112)。 気になる誤嚥には有意差なし。 肥満や呼吸不全の存在はよりこの戦略を支持。 https://t.co/TeyJsqEylL
@JonathanCaseyMD & @KevinGibbsMD summarise the #PREOXItrial, which they presented this morning at #CCR24 and was simultaneously published in @NEJM https://t.co/4Awp1u7axg @PCCRG https://t.co/1wyNk5upHu
All mentions
Critical Care Review: Key Studies from TBS Zermatt 2025
Rob Mac Sweeney reviews the year’s vital studies in critical care, including HEMOTION, PREOXI, BLING3, TRAUMAOX2, and CLASSIC. Discover the significance of noninvasive ventilation in reducing hypoxemia during emergency…
Impact of Noninvasive Ventilation on Emergency Intubation
The PREOXI trial demonstrates that preoxygenation with noninvasive ventilation significantly reduces hypoxemia and cardiac arrest during intubation compared to traditional oxygen masks. This represents a paradigm shift…
Huge practice change: BiPAP for preoxygenation (The PREOXI trial)
Noninvasive Ventilation for Preoxygenation in Intubation
In critically ill adults undergoing tracheal intubation, this video explores the effectiveness of noninvasive ventilation compared to traditional oxygen masks. The findings indicate that noninvasive ventilation…
Noninvasive Ventilation's Impact on Aspiration Risks in Intubation
The PREOXI trial dispelled concerns about aspiration risks from noninvasive ventilation. In critically ill adults, preoxygenation with noninvasive ventilation reduced hypoxemia and cardiac arrest incidents. Explore the…
Noninvasive Ventilation vs Oxygen Mask for Preoxygenation
This video explores a study comparing preoxygenation methods for critically ill patients during intubation. The research found that noninvasive ventilation significantly reduced hypoxemia and lower incidence of cardiac…
Advancements in Noninvasive Ventilation for Critical Care Medicine 2025
This video discusses important articles from 2024 relevant to pulmonary and critical care medicine, including a study on noninvasive ventilation for preoxygenation during emergency intubation, highlighting its benefits…
Impact of Noninvasive Ventilation on Preoxygenation Outcomes
In this video, I perform a critical appraisal of the PREOXI trial, comparing noninvasive ventilation to traditional oxygen masks for preoxygenation. The study shows significantly lower hypoxemia and cardiac arrest rates…
Benefits of Noninvasive Ventilation for Emergency Intubation
In this episode of the Monday Afternoon Journal Club, Dr. Mike DeFilippo reviews a study on noninvasive ventilation for preoxygenation during emergency intubation. The research demonstrates that noninvasive ventilation…
Noninvasive Ventilation for Preoxygenation Before Intubation
This tutorial details setting up a ventilator using the NIPPV/BiPAP mode for effective preoxygenation prior to endotracheal intubation. Highlighting research that shows noninvasive ventilation significantly reduces…
Preoxygenation Techniques: Noninvasive Ventilation vs Oxygen Mask
In a study involving critically ill adults undergoing tracheal intubation, researchers compared preoxygenation methods: noninvasive ventilation versus oxygen mask. The results showed a significant decrease in hypoxemia…
Overview of PREO2XI Trial on Preoxygenation Methods
This video presents a high-yield overview of the PREO2XI trial, focusing on prehospital applications. The trial examined noninvasive ventilation versus oxygen mask for preoxygenation during emergency intubation…
Noninvasive Ventilation Reduces Hypoxemia in Intubations
In a study involving critically ill adults undergoing tracheal intubation, researchers compared noninvasive ventilation with oxygen mask for preoxygenation. Hypoxemia was significantly lower in the noninvasive group…
Noninvasive Ventilation's Impact on Emergency Intubation
In this July 2024 edition of the BroomeDocs Journal Club podcast, we discuss critical emergency medicine literature. A study shows that noninvasive ventilation significantly reduces hypoxia and cardiac arrest during…
Preoxygenation Strategies: Insights from the PREOXI Trial
This panel discussion covers effective preoxygenation strategies, including findings from the PREOXI trial. It highlights a study showing that noninvasive ventilation reduces hypoxemia and cardiac arrest risk compared…
Noninvasive Ventilation Reduces Hypoxemia in Emergency Intubation
In this study, researchers found that noninvasive ventilation for preoxygenation during emergency intubation significantly reduced the incidence of hypoxemia compared to an oxygen mask, with rates of 9.1% versus 18.5%…
Investigation of Quantum Entanglement and Its Applications
This video explores the phenomenon of quantum entanglement, explaining its principles and implications in modern physics. Discover how entangled particles communicate instantaneously over distance and its potential…
Comparing Preoxygenation Techniques in Emergency Intubation
This video analyzes a study from the New England Journal of Medicine that compares preoxygenation methods for critically ill adults undergoing tracheal intubation. The research shows that noninvasive ventilation…
Noninvasive Ventilation Reduces Hypoxemia in Emergency Intubation
In a study of critically ill adults, researchers analyzed preoxygenation methods during tracheal intubation. The findings showed that noninvasive ventilation significantly reduced hypoxemia compared to oxygen masks…
Key EMS Research Findings: Year in Review 2024 Special Episode 115
102. Journal Club with BMJ Thorax – Sleep and Non-Invasive Ventilation
Journal Club: Preoxygenation Prior To Intubation
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @TBS_Zermatt: CCR's Rob Mac Sweeney's literature review from TBS25! https://t.co/Ctxii7FMGy via @YouTube
RT @TBS_Zermatt: CCR's Rob Mac Sweeney's literature review from TBS25! https://t.co/Ctxii7FMGy via @YouTube
RT @TBS_Zermatt: CCR's Rob Mac Sweeney's literature review from TBS25! https://t.co/Ctxii7FMGy via @YouTube
CCR's Rob Mac Sweeney's literature review from TBS25! https://t.co/Ctxii7FMGy via @YouTube
Congrats to Kevin Gibbs, MD, of @wakeforestmed on Clinical Research Achievement Award last month! Check out his fascinating research on the application of noninvasive ventilation to prevent hypoxemia in patients: https://t.co/hHis1HYJdr https://t.co/056SV5J2ko
RT @georgepapadapol: #ATS2025 pearls: Clinical Year in Review on #ICU and #ARDS: 1. Noninvasive ventilation for preoxygenation during emer…
RT @georgepapadapol: #ATS2025 pearls: Clinical Year in Review on #ICU and #ARDS: 1. Noninvasive ventilation for preoxygenation during emer…
#ATS2025 pearls: Clinical Year in Review on #ICU and #ARDS: 1. Noninvasive ventilation for preoxygenation during emergency intubation (results of the PREOXI Trial): -PREOXI was a large, multicenter, RCT comparing 2 preoxygenation strategies for adults undergoing emergency https://t.co/tfKAeCZ4Nb
#ATS2025 pearls: Clinical Year in Review on #ICU and #ARDS: 1. Noninvasive ventilation for preoxygenation during emergency intubation (results of the PREOXI Trial): -PREOXI was a large, multicenter, RCT comparing 2 preoxygenation strategies for adults undergoing emergency https://t.co/l3xuF89e81
PCCM FELLOWS JOURNAL CLUB
RT @emergmedottawa: Noninvasive Ventilation for Preoxygenation during Emergency Intubation via @NEJM https://t.co/wjSeszfGK2 Interpretation…
RT @emergmedottawa: Noninvasive Ventilation for Preoxygenation during Emergency Intubation via @NEJM https://t.co/wjSeszfGK2 Interpretation…
RT @emergmedottawa: Noninvasive Ventilation for Preoxygenation during Emergency Intubation via @NEJM https://t.co/wjSeszfGK2 Interpretation…
RT @emergmedottawa: Noninvasive Ventilation for Preoxygenation during Emergency Intubation via @NEJM https://t.co/wjSeszfGK2 Interpretation…
RT @emergmedottawa: Noninvasive Ventilation for Preoxygenation during Emergency Intubation via @NEJM https://t.co/wjSeszfGK2 Interpretation…
RT @emergmedottawa: Noninvasive Ventilation for Preoxygenation during Emergency Intubation via @NEJM https://t.co/wjSeszfGK2 Interpretation…
RT @emergmedottawa: Noninvasive Ventilation for Preoxygenation during Emergency Intubation via @NEJM https://t.co/wjSeszfGK2 Interpretation…
Noninvasive Ventilation for Preoxygenation during Emergency Intubation via @NEJM https://t.co/wjSeszfGK2 Interpretation: NIV should be considered for preox in critically ill patients undergoing intubation, particularly in settings with trained personnel and appropriate equipment https://t.co/izca3SbYE0
The APAPP Critical Care Journal Club will be meeting 3/5 at 8 pm EST. The Journal Club will be led by one of the authors/principal investigators, Susan Stempek, PA. Article link: https://t.co/vb4WeNLQ55 Zoom meeting link: https://t.co/cF1JSAO54O RSVP to rheavotipka@gmail.com https://t.co/OzigcDOJf7
Preoxygenation with NIV reduces hypoxemia during tracheal intubation in critically ill adults vs. oxygen mask (9.1% vs. 18.5%). Fewer cardiac arrests too (0.2% vs. 1.1%). A game-changer for safer intubations! #NIV #Intubation #Preoxyen #Emergencymedicine https://t.co/0WJjCJgzBo https://t.co/kTk2cqR8bF
Journal club: PREOXI RCT Noninvasive Ventilation for Preoxygenation duri... https://t.co/tmMRsRVGCA via @YouTube
Journal club: PREOXI RCT Noninvasive Ventilation for Preoxygenation during Emergency Intubation|nice_sable2868 @8nrdRekCQX70016 #note https://t.co/9eiBhcau6v
RT @armyemdoc: Paper #1: Noninvasive Ventilation for Preoxygenation during Emergency Intubation, Gibbs et al, New England Journal of Medic…
RT @armyemdoc: Paper #1: Noninvasive Ventilation for Preoxygenation during Emergency Intubation, Gibbs et al, New England Journal of Medic…
Paper #1: Noninvasive Ventilation for Preoxygenation during Emergency Intubation, Gibbs et al, New England Journal of Medicine Question: Should we use NIPPV instead of a standard oxygen mask for preoxygenation before emergency intubation? Lesson Learned: NIPPV reduced the
RT @YukiKotani5: 4⃣RCT on NIV vs. face mask for preoxygenation during emergency intubation - Large (N = 1310), multicentric - Reduction in…
https://t.co/ox4uqnEyHK
Thank you to our very own Grace Gao, MD for presenting at our Pediatric Journal Club. Grace is a First-Year Pediatric Critical Care Fellow. She presented: "Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI Trial)" https://t.co/D5T19Hm5cF
Paper 5: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (Pre-Oxi trial) P: Critically ill adults I: Pre-ox with NIV C: Mask (NRB or BVM) O: Hypoxemia <85%
RT @_Anesthesiology: In "Noninvasive ventilation for preoxygenation during emergency intubation," researchers randomized critically ill adu…
Another great suggestion has been the PREOXI trial in @NEJM : https://t.co/18iObtlSH8 Keep the suggestions coming!
RT @_Anesthesiology: In "Noninvasive ventilation for preoxygenation during emergency intubation," researchers randomized critically ill adu…
RT @_Anesthesiology: In "Noninvasive ventilation for preoxygenation during emergency intubation," researchers randomized critically ill adu…
RT @_Anesthesiology: In "Noninvasive ventilation for preoxygenation during emergency intubation," researchers randomized critically ill adu…
RT @_Anesthesiology: In "Noninvasive ventilation for preoxygenation during emergency intubation," researchers randomized critically ill adu…
RT @_Anesthesiology: In "Noninvasive ventilation for preoxygenation during emergency intubation," researchers randomized critically ill adu…
RT @_Anesthesiology: In "Noninvasive ventilation for preoxygenation during emergency intubation," researchers randomized critically ill adu…
RT @_Anesthesiology: In "Noninvasive ventilation for preoxygenation during emergency intubation," researchers randomized critically ill adu…
RT @_Anesthesiology: In "Noninvasive ventilation for preoxygenation during emergency intubation," researchers randomized critically ill adu…
RT @_Anesthesiology: In "Noninvasive ventilation for preoxygenation during emergency intubation," researchers randomized critically ill adu…
RT @_Anesthesiology: In "Noninvasive ventilation for preoxygenation during emergency intubation," researchers randomized critically ill adu…
RT @_Anesthesiology: In "Noninvasive ventilation for preoxygenation during emergency intubation," researchers randomized critically ill adu…
RT @_Anesthesiology: In "Noninvasive ventilation for preoxygenation during emergency intubation," researchers randomized critically ill adu…
RT @_Anesthesiology: In "Noninvasive ventilation for preoxygenation during emergency intubation," researchers randomized critically ill adu…
In "Noninvasive ventilation for preoxygenation during emergency intubation," researchers randomized critically ill adults requiring tracheal intubation to receive preoxygenation with either BIPAP or an oxygen mask. Read the October 2024 SM&A summary: https://t.co/LYIIFeaegG https://t.co/xU1SNPIJ9W
Check out the PREOXI trial, looking at hypoxemia during intubation of ICU patients trialing pre-oxygenation with non-invasive ventilation compared with a conventional oxygen mask. https://t.co/rkP5f1QgLM How does your institution preoxygenate ICU patients before intubation?
@SpiritHalloween would like to remind you of our PREOXI trial results in the @NEJM Preoxygenation for endotracheal intubation using NIPPV instead of oxygen mask resulted in -Less hypoxic events (NNT=11) -Less peri-intubation cardiac arrest (NNT=111) https://t.co/8sotQg8xp6 https://t.co/QRmbWCBYOe
Noninvasive Ventilation for Preoxygenation during Emergency Intubation https://t.co/RhWNA6Bgqo #anesthesia #anesthesiology #noninvasive #ventilation #emergency #intubation https://t.co/eMjv7rO2TV
Noninvasive Ventilation for Preoxygenation during Emergency Intubation https://t.co/usJU7S0mZj #anesthesia #anesthesiology #noninvasive #ventilation #emergency #intubation https://t.co/58t6XkN4CI
RT @YoungDGINA: Sei dabei, wenn wir am Mittwoch (25.09.) von 19:00-20:00 Uhr in entspannter Runde ein Paper durchgehen, das sich der NIV zu…
Sei dabei, wenn wir am Mittwoch (25.09.) von 19:00-20:00 Uhr in entspannter Runde ein Paper durchgehen, das sich der NIV zur Präoxygenierung annimmt!
preoxygenation is best achieved with tight fitting mask delivering 100% 02 - this is embedded practice. why are we still questioning this?! https://t.co/A79QSd1oHa
Noninvasive Ventilation for Preoxygenation during Emergency Intubation #EM #EmergencyMedicine #Airway #FOAMed https://t.co/1R83EPYMOL
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
Thank you to our very own Arnab Chowdhury, MD for presenting at our Adult Journal Club yesterday. Arnab is a Second-Year Adult Internal Medicine Critical Care Fellow. He presented: Noninvasive Ventilation for Preoxygenation during Emergency Intubation. https://t.co/lXYcW5Ejbo
البيبر https://t.co/raMrVJrezu
RT @probstMD: Great turnout for our recent @ColumbiaEM and @NYEmergency Journal Club reviewing the PREOXI trial from @NEJM ➡️Pragmatic RC…
Great turnout for our recent @ColumbiaEM and @NYEmergency Journal Club reviewing the PREOXI trial from @NEJM ➡️Pragmatic RCT looking at NIV for preoxygenation prior to RSI. https://t.co/BYw75eG9lO https://t.co/Qz6qMltaMN
RT @First10EM: The #FOAMed BroomeDocs Journal club podcast is now up on Youtube for anyone who enjoys long long discussions of evidence bas…
RT @First10EM: The #FOAMed BroomeDocs Journal club podcast is now up on Youtube for anyone who enjoys long long discussions of evidence bas…
The #FOAMed BroomeDocs Journal club podcast is now up on Youtube for anyone who enjoys long long discussions of evidence based medicine @broomedocs https://t.co/l2J5sOFPPR
RT @TheSGEM: Link to PREOXI Trial published in NEJM https://t.co/Oc35dNbMnf
Link to PREOXI Trial published in NEJM https://t.co/Oc35dNbMnf
低酸素も重要な有害事象です。こちらについては、NIVによる前酸素化が注目です! 6月に発表された多施設RCTでは、酸素マスクに比べてNIVを用いた前酸素化は、SpO2<85%の低酸素を18.5%→9.1%と半減させる、という結果でした。 更に心停止も1.1%→0.2%と減少しました。 https://t.co/qfWDfENgjt
Nice summary and insightful thoughts on the recent trial comparing NIV vs. oxygen mask as a preoxygenation method before emergent intubation https://t.co/qfWDfENgjt https://t.co/YHJNxchJcv
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
Journal Club: Noninvasive Ventilation for Preoxygenation during Emergency Intubation https://t.co/VWcHO59wcZ
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
RT @OrlandoRPN: Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién p…
Taller de Preoxigenación con VNI antes de la Intubación de Emergencia Siguiendo el protocolo del estudio #PREOXI recién publicado, para disminuir la incidencia de hipoxemia y paro peri-intubación DOI:10.1056/NEJMoa2313680 Aplicando la mejor evidencia inmediatamente #UCIHGSJR https://t.co/LXSjdjnonD
RT @SOCCA_CritCare: The results of the PREOXI trial suggest that noninvasive ventilation is more effective than an oxygen mask for preoxyge…
The results of the PREOXI trial suggest that noninvasive ventilation is more effective than an oxygen mask for preoxygenation during tracheal intubation in preventing hypoxemia. Will this change your practice? https://t.co/6csjbTnNK9
RT @SCCM_Anesth: Gibbs et al publish their findings regarding NIV vs simple mask for preoxygenation during emergency intubation in @NEJM
RT @SCCM_Anesth: Gibbs et al publish their findings regarding NIV vs simple mask for preoxygenation during emergency intubation in @NEJM
RT @SCCM_Anesth: Gibbs et al publish their findings regarding NIV vs simple mask for preoxygenation during emergency intubation in @NEJM
Gibbs et al publish their findings regarding NIV vs simple mask for preoxygenation during emergency intubation in @NEJM
RT @YukiKotani5: 4⃣RCT on NIV vs. face mask for preoxygenation during emergency intubation - Large (N = 1310), multicentric - Reduction in…
RT @georgepapadapol: Ventilación mecánica no invasiva como estrategia de pre oxigenación durante la intubación de emergencia: Disminuyó la…
RT @georgepapadapol: Ventilación mecánica no invasiva como estrategia de pre oxigenación durante la intubación de emergencia: Disminuyó la…
Ventilación mecánica no invasiva como estrategia de pre oxigenación durante la intubación de emergencia: Disminuyó la mortalidad al evitar que caigan en hipoxemia y paro periintubación:
RT @YukiKotani5: 4⃣RCT on NIV vs. face mask for preoxygenation during emergency intubation - Large (N = 1310), multicentric - Reduction in…
4⃣RCT on NIV vs. face mask for preoxygenation during emergency intubation - Large (N = 1310), multicentric - Reduction in severe hypoxia (SpO2 < 85%; 9.1% vs. 18.5%) and cardiac arrest (0.2% vs. 1.1%) https://t.co/qfWDfENgjt
4⃣緊急気管挿管の前酸素化でのNIV
Noninvasive Ventilation for Preoxygenation during Emergency Intubation | New England Journal of Medicine https://t.co/sLYFDIMXQO
RT @UABDeptMed:
RT @UABDeptMed:
Preoxygenation with noninvasive positive pressure ventilation (as opposed to a plain O2 mask) recuced the risk of hypoxemia (sat <86%) from 18% to 9% (P<0.001) in this study of ED patients undergoing emergency intubation https://t.co/74V7y7kQS5
RT @UABDeptMed:
Noninvasive Ventilation for Preoxygenation during Emergency Intubation https://t.co/aLWNmO1b9U
Noninvasive Ventilation for Preoxygenation during Emergency Intubation | New England Journal of Medicine https://t.co/vJDIt2RGRP NIV significantly reduces hypoxemia during emergency intubation compared to oxygen masks. #CriticalCare #Intubation #MedicalResearch
RT @natetexsun: OK #NeoTwitter, Who did it better? The SHINE trial by @drbretty et al or this @NEJM paper in adults? Non-invasive ventilati…
VNI para Pre oxigenación durante intubación de emergencia se asocia con mejor mortalidad y paros periintubación:
@sarahkmels @djc795 @apsmunro @statsepi Interesting, perhaps you can tell the authors of this recent NEJM paper that their randomization scheme is the equivalent of a med student research study with inferior methodology to junior high science fairs https://t.co/TDcSEYxWph
RT @LeslieMegom: ⏩️La preoxigenación con ventilación no invasiva resultó en una
RT @CritCareReviews: @JonathanCaseyMD & @KevinGibbsMD summarise the #PREOXItrial, which they presented this morning at #CCR24 and was simul…
RT @LaViaAerea: #PREOXI Ventilación No Invasiva para #Preoxigenación durante la #Intubación de Emergencia #VMNI vs #NRM https://t.co/gr…
Preoxigenación con máscara vs no invasiva en secuencia de intubación rápida.. < Riesgo de arresto cardíaco en el grupo de NIV en preoxigenación.
RT @NEJM: PREOXI trial: Researchers evaluated whether preoxygenation with noninvasive ventilation would be more effective in decreasing the…
RT @NEJM: PREOXI trial: Researchers evaluated whether preoxygenation with noninvasive ventilation would be more effective in decreasing the…
RT @NEJM: PREOXI trial: Researchers evaluated whether preoxygenation with noninvasive ventilation would be more effective in decreasing the…
RT @ZainKhalpey: Researchers investigated if preoxygenation with noninvasive ventilation can better reduce hypoxemia risk compared to an ox…
RT @NEJM: PREOXI trial: Researchers evaluated whether preoxygenation with noninvasive ventilation would be more effective in decreasing the…
RT @NEJM: PREOXI trial: Researchers evaluated whether preoxygenation with noninvasive ventilation would be more effective in decreasing the…
RT @NEJM: PREOXI trial: Researchers evaluated whether preoxygenation with noninvasive ventilation would be more effective in decreasing the…
RT @NEJM: PREOXI trial: Researchers evaluated whether preoxygenation with noninvasive ventilation would be more effective in decreasing the…
RT @NEJM: PREOXI trial: Researchers evaluated whether preoxygenation with noninvasive ventilation would be more effective in decreasing the…
RT @NEJM: PREOXI trial: Researchers evaluated whether preoxygenation with noninvasive ventilation would be more effective in decreasing the…
RT @NEJM: PREOXI trial: Researchers evaluated whether preoxygenation with noninvasive ventilation would be more effective in decreasing the…
RT @NEJM: PREOXI trial: Researchers evaluated whether preoxygenation with noninvasive ventilation would be more effective in decreasing the…
RT @NEJM: PREOXI trial: Researchers evaluated whether preoxygenation with noninvasive ventilation would be more effective in decreasing the…
RT @NEJM: PREOXI trial: Researchers evaluated whether preoxygenation with noninvasive ventilation would be more effective in decreasing the…
RT @NEJM: PREOXI trial: Researchers evaluated whether preoxygenation with noninvasive ventilation would be more effective in decreasing the…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
New Study: Noninvasive Ventilation for Preoxygenation during Emergency Intubation | New England Journal of Medicine https://t.co/z6l6MYkQAI
Noninvasive Ventilation for Preoxygenation during Emergency Intubation | New England Journal of Medicine https://t.co/Z4osmD1t6v
RT @KaminskiMed: Interesting: Noninvasive Ventilation for Preoxygenation during Emergency Intubation | New England Journal of Medicine http…
Noninvasive Ventilation for Preoxygenation during Emergency Intubation | New England Journal of Medicine https://t.co/QKmeaYGJyr
RT @KaminskiMed: Interesting: Noninvasive Ventilation for Preoxygenation during Emergency Intubation | New England Journal of Medicine http…
Interesting: Noninvasive Ventilation for Preoxygenation during Emergency Intubation | New England Journal of Medicine https://t.co/BTxNrUvukB
https://t.co/DcWau6KRJV
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @MasayukiToc: ERとICUでの重篤な成人患者1300人を対象にしたPREOXI試験、結果が明らかに! NIPPV vs マスクでのpre-oxygenation戦略を比較。 NIPPVは重篤なSpO2低下を防ぎ、心停止リスク減少(NNT112)。 気にな…
Noninvasive Ventilation for Preoxygenation during Emergency Intubation #science #publication #research #publications https://t.co/uuMZXWMeFR
RT @MasayukiToc: Game changer論文! これだけの効果があるならpre-oxygenationにNPPVを使わない手はない! でも実際は手間すぎて必要な患者(肥満や低酸素血症など解剖学的/生理学的difficult airwayなど)に絞ってやるこ…
RT @MasayukiToc: ERとICUでの重篤な成人患者1300人を対象にしたPREOXI試験、結果が明らかに! NIPPV vs マスクでのpre-oxygenation戦略を比較。 NIPPVは重篤なSpO2低下を防ぎ、心停止リスク減少(NNT112)。 気にな…
RT @MasayukiToc: ERとICUでの重篤な成人患者1300人を対象にしたPREOXI試験、結果が明らかに! NIPPV vs マスクでのpre-oxygenation戦略を比較。 NIPPVは重篤なSpO2低下を防ぎ、心停止リスク減少(NNT112)。 気にな…
RT @MasayukiToc: ERとICUでの重篤な成人患者1300人を対象にしたPREOXI試験、結果が明らかに! NIPPV vs マスクでのpre-oxygenation戦略を比較。 NIPPVは重篤なSpO2低下を防ぎ、心停止リスク減少(NNT112)。 気にな…
RT @MasayukiToc: Game changer論文! これだけの効果があるならpre-oxygenationにNPPVを使わない手はない! でも実際は手間すぎて必要な患者(肥満や低酸素血症など解剖学的/生理学的difficult airwayなど)に絞ってやるこ…
RT @MasayukiToc: Game changer論文! これだけの効果があるならpre-oxygenationにNPPVを使わない手はない! でも実際は手間すぎて必要な患者(肥満や低酸素血症など解剖学的/生理学的difficult airwayなど)に絞ってやるこ…
RT @First10EM: A potential huge game changer: BiPAP for preoxygenation - the PREOXI trial https://t.co/j0nECJP7Ru
RT @MasayukiToc: Game changer論文! これだけの効果があるならpre-oxygenationにNPPVを使わない手はない! でも実際は手間すぎて必要な患者(肥満や低酸素血症など解剖学的/生理学的difficult airwayなど)に絞ってやるこ…
RT @MasayukiToc: Game changer論文! これだけの効果があるならpre-oxygenationにNPPVを使わない手はない! でも実際は手間すぎて必要な患者(肥満や低酸素血症など解剖学的/生理学的difficult airwayなど)に絞ってやるこ…
RT @MasayukiToc: Game changer論文! これだけの効果があるならpre-oxygenationにNPPVを使わない手はない! でも実際は手間すぎて必要な患者(肥満や低酸素血症など解剖学的/生理学的difficult airwayなど)に絞ってやるこ…
RT @MasayukiToc: Game changer論文! これだけの効果があるならpre-oxygenationにNPPVを使わない手はない! でも実際は手間すぎて必要な患者(肥満や低酸素血症など解剖学的/生理学的difficult airwayなど)に絞ってやるこ…
Game changer論文! これだけの効果があるならpre-oxygenationにNPPVを使わない手はない! でも実際は手間すぎて必要な患者(肥満や低酸素血症など解剖学的/生理学的difficult airwayなど)に絞ってやることになりそうな。 NC全開+BVM(±PEEPバルブ)で大体はまかなえるか https://t.co/TeyJsqE0wd
ERとICUでの重篤な成人患者1300人を対象にしたPREOXI試験、結果が明らかに! NIPPV vs マスクでのpre-oxygenation戦略を比較。 NIPPVは重篤なSpO2低下を防ぎ、心停止リスク減少(NNT112)。 気になる誤嚥には有意差なし。 肥満や呼吸不全の存在はよりこの戦略を支持。 https://t.co/TeyJsqEylL
RT @First10EM: A potential huge game changer: BiPAP for preoxygenation - the PREOXI trial https://t.co/j0nECJP7Ru
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
A potential huge game changer: BiPAP for preoxygenation - the PREOXI trial https://t.co/j0nECJP7Ru
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @CritCareReviews: @JonathanCaseyMD & @KevinGibbsMD summarise the #PREOXItrial, which they presented this morning at #CCR24 and was simul…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @CritCareReviews: @JonathanCaseyMD & @KevinGibbsMD summarise the #PREOXItrial, which they presented this morning at #CCR24 and was simul…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @CritCareReviews: @JonathanCaseyMD & @KevinGibbsMD summarise the #PREOXItrial, which they presented this morning at #CCR24 and was simul…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @KhannaAshishCCM: Noninvasive Ventilation for Preoxygenation during Emergency Intubation | New England Journal of Medicine https://t.co/…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @CritCareReviews: @JonathanCaseyMD & @KevinGibbsMD summarise the #PREOXItrial, which they presented this morning at #CCR24 and was simul…
RT @CritCareReviews: @JonathanCaseyMD & @KevinGibbsMD summarise the #PREOXItrial, which they presented this morning at #CCR24 and was simul…
RT @CritCareReviews: @JonathanCaseyMD & @KevinGibbsMD summarise the #PREOXItrial, which they presented this morning at #CCR24 and was simul…
RT @CritCareReviews: @JonathanCaseyMD & @KevinGibbsMD summarise the #PREOXItrial, which they presented this morning at #CCR24 and was simul…
RT @CritCareReviews: @JonathanCaseyMD & @KevinGibbsMD summarise the #PREOXItrial, which they presented this morning at #CCR24 and was simul…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @CritCareReviews: @JonathanCaseyMD & @KevinGibbsMD summarise the #PREOXItrial, which they presented this morning at #CCR24 and was simul…
RT @CritCareReviews: @JonathanCaseyMD & @KevinGibbsMD summarise the #PREOXItrial, which they presented this morning at #CCR24 and was simul…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @KhannaAshishCCM: Noninvasive Ventilation for Preoxygenation during Emergency Intubation | New England Journal of Medicine https://t.co/…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @intensivecare_c: 重症患者の気管挿管での前酸素化はNIV(Bilevel PAP)?、それともマスク? NIV群の方が低酸素血症(SpO2<85%)が少ない(9.1% vs. 18.5%)という結果。 PREOXI trial https://t.…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @CritCareReviews: @JonathanCaseyMD & @KevinGibbsMD summarise the #PREOXItrial, which they presented this morning at #CCR24 and was simul…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @KhannaAshishCCM: Noninvasive Ventilation for Preoxygenation during Emergency Intubation | New England Journal of Medicine https://t.co/…
RT @KhannaAshishCCM: Noninvasive Ventilation for Preoxygenation during Emergency Intubation | New England Journal of Medicine https://t.co/…
Noninvasive Ventilation for Preoxygenation during Emergency Intubation | New England Journal of Medicine https://t.co/4KXJRYYlK7 Congratulations @WakePCCM @KevinGibbsMD & team! @wakeforestmed @SCCM
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @Fauconnoir0: Noninvasive Ventilation for Preoxygenation during Emergency Intubation | New England Journal of Medicine https://t.co/joyC…
Noninvasive Ventilation for Preoxygenation during Emergency Intubation | New England Journal of Medicine https://t.co/joyCVFlZeX
RT @VishankShah3: Noninvasive Ventilation for Preoxygenation during Emergency Intubation | New England Journal of Medicine https://t.co/HAG…
RT @NEJM: Original Article: Noninvasive Ventilation for Preoxygenation during Emergency Intubation (PREOXI) https://t.co/4C2TS0VA6c #CCR2…
RT @intensivecare_c: 重症患者の気管挿管での前酸素化はNIV(Bilevel PAP)?、それともマスク? NIV群の方が低酸素血症(SpO2<85%)が少ない(9.1% vs. 18.5%)という結果。 PREOXI trial https://t.…
重症患者の気管挿管での前酸素化はNIV(Bilevel PAP)?、それともマスク? NIV群の方が低酸素血症(SpO2<85%)が少ない(9.1% vs. 18.5%)という結果。 PREOXI trial https://t.co/Zh44Gq4ZwN
RT @CritCareReviews: @JonathanCaseyMD & @KevinGibbsMD summarise the #PREOXItrial, which they presented this morning at #CCR24 and was simul…
RT @CritCareReviews: @JonathanCaseyMD & @KevinGibbsMD summarise the #PREOXItrial, which they presented this morning at #CCR24 and was simul…
RT @CritCareReviews: @JonathanCaseyMD & @KevinGibbsMD summarise the #PREOXItrial, which they presented this morning at #CCR24 and was simul…
@JonathanCaseyMD & @KevinGibbsMD summarise the #PREOXItrial, which they presented this morning at #CCR24 and was simultaneously published in @NEJM https://t.co/4Awp1u7axg @PCCRG https://t.co/1wyNk5upHu
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