J Am Coll Cardiol July 2024 PMID 38925728

Lessons for Cardiovascular Clinical Investigators: The Tumultuous 2,500-Year Journey of Physicians Who Ignited Our Fire.

Milton Packer

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Peak: 33 in Jun 2024

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The discussions highlight the article’s compelling historical overview, with phrases like 'fascinating read' and 'wonderful journey through time' indicating enthusiasm and appreciation for its depth. The mention of how advances were initially ridiculed and the importance of humility and mentorship suggest that the publication encourages reflection on both historical context and future challenges in cardiology, emphasizing its perceived significance in the field.

AgreementModerate agreement

Most discussions acknowledge the article’s historical insights and its relevance to current cardiovascular medicine, indicating general support.

InterestHigh interest

The posts express high curiosity, with comments calling the review 'fascinating' and noting its appeal across all career stages, showing engagement with the subject matter.

EngagementModerate engagement

Some comments reference specific parts of the publication, such as advances in CV medicine being initially ridiculed, demonstrating a moderate-to-deep level of engagement.

ImpactModerate impact

The discussions suggest that the article prompts reflection on the evolution and resistance within medical practice, pointing to its potential influence on shaping thoughts about clinical research and practice.

Abstract in brief

The roots of medical practice can be traced back to Hippocrates, while the foundation of cardiovascular science originates from Aristotle, whose ideas were initially suppressed but later flourished during the Islamic Golden Age due to a lack of religious constraints.
Galen, a prominent physician, established a long-lasting view of blood circulation composed of separate venous and arterial systems, portraying the heart as a sucking organ, which dominated medical thought for over 1,300 years.
The University of Padua became a crucial site for the rebirth of Aristotelian science and the challenge to Galen’s theories, leading to breakthroughs by figures like William Harvey, who proposed a closed circulatory system but faced ridicule and delayed acceptance for his

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All mentions

Historical Insights into Cardiovascular Medicine and Its Evolution

Harlan Krumholz and Milton Packer explore the history of cardiovascular science, highlighting how early ideas from Aristotle and Galen shaped medical thought, and how breakthroughs like William Harvey's discovery of…

American College of Cardiology · Jun 27, 2024 299 views

Lessons for CV Clin Investigators: A Tumultuous Journey of Physicians Who Ignited Our Fire | JACC

American College of Cardiology · Jun 27, 2024 200 views

Innovative Pioneers in Cardiology History and Progress

Harlan Krumholz and Milton Packer explore the history of cardiology, highlighting young rebels whose daring ideas revolutionized the field. Their perseverance and innovative thinking paved the way for groundbreaking…

American College of Cardiology · Jun 27, 2024 191 views

Dr. Eman

@DrEmanreads · X

Lessons for Cardiovascular Clinical Investigators: The Tumultuous 2,500-Year Journey of Physicians Who Ignited Our Fire

Jul 10, 2024 · 1,232 followers View post →

Wei-Guo Ma, MD

@Dr_Ma_of_PUMC · X

Lessons for Cardiovascular Clinical Investigators: The Tumultuous 2,500-Year Journey of Physicians Who Ignited Our Fire https://t.co/KlFw6LnhdR

Jun 30, 2024 · 2 likes · 2,369 followers View post →

Leopoldo Santos-Neto

@leosantosIII · X

“moldados por eventos políticos, publicados após anos de atraso e, tipicamente, recebidos com grande resistência, muitas vezes impulsionada por ciúmes profissionais ou territorialismo.” (

Jun 28, 2024 · 579 followers View post →

Leopoldo Santos-Neto

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Jun 28, 2024 · 2 likes · 579 followers View post →

Giuseppe Biondi-Zoccai

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RT @AbbateAntonio: Lessons for Cardiovascular Clinical Investigators: The Tumultuous 2,500-Year Journey of Physicians Who Ignited Our … htt…

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JACC Journals

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AntonioAbbate

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Kamala Tamirisa MD

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