Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene therapy.
Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy.
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Jun 2023 – May 2025Where it's discussed
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X / Twitter105 posts
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What people are saying
Many discussions highlight the research's promising implications, with participants expressing enthusiasm through comments like 'I'd love to try AAV vectors to de-age myself' and referencing the transformative potential of gene therapy. The tone ranges from excitement to hopeful curiosity, contributing to a collective anticipation about the practical applications of this research.
Most discussions show a favorable view of the research, expressing optimism about its findings.
The topic has generated significant curiosity, indicated by the enthusiastic responses and shared articles.
While many comments focus on the findings, there are some engagement with methods and implications for future research.
Participants generally perceive the research as possibly leading to significant developments in cognitive longevity.
Abstract in brief
- Scientists discovered that using special genes (called OSKM) can make old cells younger and help them think better.
- They tested this on older rats and found that the ones treated with OSKM did better in memory tests than those that didn't get the treatment.
- The OSKM treatment didn't cause any harm, and it also changed the DNA in the rats' brains in a way that showed signs of "youthfulness."
Top posts
Most liked on X and BlueskyCognitive rejuvenation in old rats by hippocampal OSKM gene therapy
Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy https://t.co/rYgpmmraQx
Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy @prof_horvath , Rodolfo Goya et al @GeroScienceAGE https://t.co/SiVjtE1OmF https://t.co/Cq4rdKTxpS
Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy! Check out this Longevist-featured research, now published in @GeroScienceAGE https://t.co/a2vrCCSWF3 Congrats @prof_horvath @amin_haghani Rodolfo Goya @altos_labs
All mentions
July 2024 Review: Longevity Studies and Cognitive Rejuvenation
This video reviews impactful longevity studies from July 2024. Highlights include using OSKM gene therapy to rejuvenate old rat cells, enhancing their memory. The findings suggest potential applications for improving…
Reversing Cognitive Decline in Aging Rats via OSKM Gene Therapy
This study investigates the potential of Yamanaka gene therapy using the OSKM transcription factors to reverse age-related cognitive decline in old rats. Results demonstrate improved memory performance in treated rats…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
@DrNeilStone I'd love to try AAV vectors to de age myself whenever I get the chance to & I'd even volunteer for a trial. https://t.co/xJPcIJVEUP https://t.co/SnQQidsNeD https://t.co/yPB6v0oVhh
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @agingdoc1: Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy @prof_horvath , Rodolfo Goya et al @GeroScienceAGE ht…
RT @agingdoc1: Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy @prof_horvath , Rodolfo Goya et al @GeroScienceAGE ht…
RT @agingdoc1: Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy @prof_horvath , Rodolfo Goya et al @GeroScienceAGE ht…
RT @agingdoc1: Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy @prof_horvath , Rodolfo Goya et al @GeroScienceAGE ht…
Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy @prof_horvath , Rodolfo Goya et al @GeroScienceAGE https://t.co/SiVjtE1OmF https://t.co/Cq4rdKTxpS
Can old rats brains be made young again? https://t.co/Hkelz1Nt8g via @YouTube
RT @gglinskii: Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy https://t.co/59PulhGPOl
Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy https://t.co/59PulhGPOl
RT @canlongevity: The latest Longevity Review Newsletter and Video for July is now out. Rushed this one out so that I can finally take a tw…
The latest Longevity Review Newsletter and Video for July is now out. Rushed this one out so that I can finally take a two week break from scouring Pubmed and posting on social media - my first lengthy break in five years! 1/2 Video: https://t.co/e8WQlWrtFz
July's second half picks ! (2/2) Yamanaka factors for the win: https://t.co/9xsDXexc53 Trametinib +rapamycin more effective than either alone : https://t.co/SyBqdvuNvt Marine peptides join the race: https://t.co/pSqXiBZhLj
https://t.co/yXVBgA7MG3
RT @longevist_xyz: Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy! Check out this Longevist-featured research, now pub…
Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy! Check out this Longevist-featured research, now published in @GeroScienceAGE https://t.co/a2vrCCSWF3 Congrats @prof_horvath @amin_haghani Rodolfo Goya @altos_labs
RT @agingdoc1: Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy
Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy https://t.co/uvpe3Q58tO
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
https://t.co/pCYRnpPEEo
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @agingdoc1: Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy
Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy | GeroScience https://t.co/ThAPDE05S5
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
2/2 The author's concluded that "our findings add to the growing evidence supporting the potential of in vivo Yamanaka gene therapy as a rejuvenation strategy." https://t.co/COrJ3SJNDA
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @agingdoc1: Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy
RT @agingdoc1: Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy
Estudo revela que terapia gênica com fatores de reprogramação Yamanaka (OSKM) melhora significativamente a memória espacial em ratos idosos, sem alterações patológicas. https://t.co/mV6P3MSws9
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy. "In summary, the administration of Yamanaka genes via viral vectors rejuvenates the functional capabilities and the epigenetic landscape of the rat hippocampus." https://t.co/0FVxvzXciE
RT @agingdoc1: Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy
RT @agingdoc1: Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @agingdoc1: Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy
RT @agingdoc1: Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy
RT @agingdoc1: Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy
RT @AgingBiology: Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy https://t.co/rYgpmmraQx
RT @agingdoc1: Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy
Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy
RT @AgingBiology: Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy https://t.co/rYgpmmraQx
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @INSPIREPlatfor1: Brain tissue : "Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy." https://t.co/66iF43S7D7 @isapera…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
Brain tissue : "Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy." https://t.co/66iF43S7D7 @isaperarnau @brunovellas @RestoreInstitut @InfinityTLS @I2mcT
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
@statto I believe this is the research you're looking for? https://t.co/UqoTUbXbUs https://t.co/h478Fpdira
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @gglinskii: Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy https://t.co/qX1c5CZuiM
Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy https://t.co/qX1c5CZuiM
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy By Steve Horvath @prof_horvath https://t.co/K0bF5M7uLE
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @AgingBiology: Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy https://t.co/rYgpmmraQx
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy https://t.co/rYgpmmraQx
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy | GeroScience https://t.co/eOLwioNSBH
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
RT @prof_horvath: Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene ther…
Rejuvenation of memory and DNA methylation in the hippocampus of 2 year old rats via Yamanaka factor adenovirus gene therapy.
COGNITIVE REJUVENATION IN OLD RATS BY HIPPOCAMPAL OSKM GENE THERAPY https://t.co/iRssZ1JMj1
RT @agingdoc1: Cognitive Rejuvenation in Old Rats By Hippocampal OSKM Gene Therapy @prof_horvath, Rodolfo Goya, coauthors @altos_labs ht…
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