PubHawk
September 2024 PMID 39117797

Spermidine is essential for fasting-mediated autophagy and longevity.

Sebastian J Hofer, Ioanna Daskalaki, Martina Bergmann, Jasna Friščić, Andreas Zimmermann, Melanie I Mueller, Mahmoud Abdellatif, Raffaele Nicastro, Sarah Masser, Sylvère Durand, Alexander Nartey, Mara Waltenstorfer, Sarah Enzenhofer, Isabella Faimann, Verena Gschiel

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Mentions

86
Peak: 53 in Aug 2024
across 6 sources since Aug 2024

Extended reach

761,790
potential audience

Total likes

584

Video views

5,630

Mentions per month

Aug 2024 – Jan 2026

Where it's discussed

  • X / Twitter54 posts
  • News23 articles
  • YouTube3 videos
  • Facebook2 posts
  • Reddit2 posts
  • Blogs2 articles

AI synopsis

What people are saying

Participants use phrases like 'essential for fasting-mediated autophagy and longevity' consistently, and cite influential figures such as Frank Madeo, demonstrating both appreciation and recognition of the research's significance. The tone is predominantly supportive and inquisitive, emphasizing the potential impact on health and aging.

AgreementStrong agreement

Most discussions express strong support for the importance of spermidine in fasting and longevity, showing unanimous agreement with the publication.

InterestHigh interest

The recurring emphasis on autophagy, longevity, and the biological pathways suggests a high level of interest among participants.

EngagementHigh engagement

Many posts cite specific research details, mention prominent researchers, and share related images, reflecting deep engagement.

ImpactHigh impact

The widespread sharing and repeated endorsement indicate that this research potentially influences scientific perspectives and health considerations.

Abstract in brief

  • Caloric restriction and intermittent fasting improve lifespan and health by enhancing cellular processes influenced by the polyamine spermidine.
  • Levels of spermidine increase during fasting and caloric restriction in various organisms, suggesting its role in promoting health benefits.
  • Disruption of spermidine production negatively affects fasting-related health improvements, highlighting its essential role in autophagy and longevity.
Read the full abstract

Top posts

Most liked on X and Bluesky
Bruno Ramos-Molina, PhD
@Brunorm84 · X

Spermidine is essential for #fasting-mediated #autophagy and #longevity @NatureCellBio https://t.co/jqntINULBO

Aug 9, 2024 · 47 likes · 12 shares · 6,433 followers View post →
P.D. Mangan Health & Freedom Maximalist
@Mangan150 · X

New: Spermidine is essential for fasting-mediated autophagy and longevity "perturbing the polyamine pathway in vivo abrogated the lifespan- and healthspan-extending effects, as well as the cardioprotective and anti-arthritic consequences of fasting" https://t.co/oOrrXndBSs

Aug 15, 2024 · 43 likes · 291,252 followers View post →
Aging Science News
@AgingBiology · X

Spermidine is essential for fasting-mediated autophagy and longevity https://t.co/E8nLpLjV0W

Aug 10, 2024 · 35 likes · 6 shares · 30,527 followers View post →
Cell Biology J-Club
@cell_club · X

Spermidine is essential for fasting-mediated autophagy and longevity https://t.co/vAk89sUcPh

Aug 8, 2024 · 34 likes · 11 shares · 6,090 followers View post →
P.D. Mangan Health & Freedom Maximalist
@Mangan150 · X

Spermidine is essential for fasting-mediated autophagy and longevity https://t.co/oOrrXndBSs

Sep 6, 2024 · 33 likes · 1 share · 291,252 followers View post →
Gilles Gouspillou
@GGouspillou · X

Spermidine is essential for fasting-mediated autophagy and longevity | Nature Cell Biology https://t.co/gX3M0llrlO

Aug 9, 2024 · 30 likes · 6 shares · 1,818 followers View post →

All mentions

Shubham Mishra
@brahma_4u · X

RT @Mangan150: Spermidine is essential for fasting-mediated autophagy and longevity https://t.co/oOrrXndBSs

Sep 6, 2024 · 1 share · 6,001 followers View post →
P.D. Mangan Health & Freedom Maximalist
@Mangan150 · X

Spermidine is essential for fasting-mediated autophagy and longevity https://t.co/oOrrXndBSs

Sep 6, 2024 · 33 likes · 1 share · 291,252 followers View post →
三明みこる
@MikoruMiake · X

おはようございます！ #おはようVtuber︎ shorts動画「老化と若返りを繰り返す生物がいる！？」を投稿しました！ https://t.co/jeFPu51V5r https://t.co/ekh5dU3Bpn

Aug 26, 2024 · 104 followers View post →
三明みこる
@MikoruMiake · X

おはようございます！　#おはようVtuber shorts動画「母乳を飲むと寿命が延びる！？」を投稿しました！　牛乳飲むか～ https://t.co/jeFPu51nfT https://t.co/g43IWNYcTg https://t.co/eVk2syAdZq

Aug 25, 2024 · 104 followers View post →
P.D. Mangan Health & Freedom Maximalist
@Mangan150 · X

New: Spermidine is essential for fasting-mediated autophagy and longevity "perturbing the polyamine pathway in vivo abrogated the lifespan- and healthspan-extending effects, as well as the cardioprotective and anti-arthritic consequences of fasting" https://t.co/oOrrXndBSs

Aug 15, 2024 · 43 likes · 291,252 followers View post →
Nithyanan Annamalai
@BlackSamrat · X

RT @AgingBiology: Spermidine is essential for fasting-mediated autophagy and longevity https://t.co/E8nLpLjV0W

Aug 12, 2024 · 6 shares · 373 followers View post →
Manoj Mayogi Mishra
@mayogisense · X

RT @AgingBiology: Spermidine is essential for fasting-mediated autophagy and longevity https://t.co/E8nLpLjV0W

Aug 12, 2024 · 6 shares · 573 followers View post →
nike
@wot_mikey · X

RT @AgingBiology: Spermidine is essential for fasting-mediated autophagy and longevity https://t.co/E8nLpLjV0W

Aug 12, 2024 · 6 shares · 464 followers View post →
John Greene
@Greene_Thoughts · X

RT @AgingBiology: Spermidine is essential for fasting-mediated autophagy and longevity https://t.co/E8nLpLjV0W

Aug 11, 2024 · 6 shares · 1,670 followers View post →
Surojit Sural
@surojitsural · X

RT @AgingBiology: Spermidine is essential for fasting-mediated autophagy and longevity https://t.co/E8nLpLjV0W

Aug 11, 2024 · 6 shares · 875 followers View post →
Life Science Journal Content
@lsn_jc · X

Spermidine is essential for fasting-mediated autophagy and longevity #science #publication #research #journal https://t.co/fWyJFraage

Aug 11, 2024 · 260 followers View post →
Aging Science News
@AgingBiology · X

Spermidine is essential for fasting-mediated autophagy and longevity https://t.co/E8nLpLjV0W

Aug 10, 2024 · 35 likes · 6 shares · 30,527 followers View post →
Well Done
@welldone00 · X

RT @GGouspillou: Spermidine is essential for fasting-mediated autophagy and longevity | Nature Cell Biology https://t.co/gX3M0llrlO

Aug 10, 2024 · 6 shares · 1,057 followers View post →
Juhana Harju
@JuhanaHarju · X

RT @GGouspillou: Spermidine is essential for fasting-mediated autophagy and longevity | Nature Cell Biology https://t.co/gX3M0llrlO

Aug 10, 2024 · 6 shares · 1,690 followers View post →
Federico Pietrocola
@FedericoPietr12 · X

RT @agingdoc1: Spermidine is essential for fasting-mediated autophagy and longevity @seb_hofer and Frank Madeo https://t.co/5EmJBnPvDK ht…

Aug 10, 2024 · 6 shares · 794 followers View post →
Elmira Khabusheva
@sciencyelmira · X

RT @Brunorm84: Spermidine is essential for #fasting-mediated #autophagy and #longevity @NatureCellBio https://t.co/jqntINULBO

Aug 10, 2024 · 12 shares · 755 followers View post →
Elmira Khabusheva
@drkhabusheva · X

RT @Brunorm84: Spermidine is essential for #fasting-mediated #autophagy and #longevity @NatureCellBio https://t.co/jqntINULBO

Aug 10, 2024 · 12 shares · 735 followers View post →
Fábio Fonseca
@FbioFon84085623 · X

RT @Brunorm84: Spermidine is essential for #fasting-mediated #autophagy and #longevity @NatureCellBio https://t.co/jqntINULBO

Aug 9, 2024 · 12 shares · 567 followers View post →
André Katayama Yamada
@KatayamaYamada · X

RT @GGouspillou: Spermidine is essential for fasting-mediated autophagy and longevity | Nature Cell Biology https://t.co/gX3M0llrlO

Aug 9, 2024 · 6 shares · 405 followers View post →
André Katayama Yamada
@KatayamaYamada · X

RT @Brunorm84: Spermidine is essential for #fasting-mediated #autophagy and #longevity @NatureCellBio https://t.co/jqntINULBO

Aug 9, 2024 · 12 shares · 405 followers View post →
SNZK
@shinopp · X

RT @agingdoc1: Spermidine is essential for fasting-mediated autophagy and longevity @seb_hofer and Frank Madeo https://t.co/5EmJBnPvDK ht…

Aug 9, 2024 · 6 shares · 722 followers View post →
Camilo J. Llamoza-Torres
@CamiloJT · X

RT @Brunorm84: Spermidine is essential for #fasting-mediated #autophagy and #longevity @NatureCellBio https://t.co/jqntINULBO

Aug 9, 2024 · 12 shares · 1,289 followers View post →
Frank Paul Mora
@InTime_49 · X

RT @Brunorm84: Spermidine is essential for #fasting-mediated #autophagy and #longevity @NatureCellBio https://t.co/jqntINULBO

Aug 9, 2024 · 12 shares · 383 followers View post →
Alexander Dakhovnik
@ADakhovnik · X

RT @agingdoc1: Spermidine is essential for fasting-mediated autophagy and longevity @seb_hofer and Frank Madeo https://t.co/5EmJBnPvDK ht…

Aug 9, 2024 · 6 shares · 77 followers View post →
Diana
@PharmphoodTM · X

RT @Brunorm84: Spermidine is essential for #fasting-mediated #autophagy and #longevity @NatureCellBio https://t.co/jqntINULBO

Aug 9, 2024 · 12 shares · 557 followers View post →
Melina Casadio
@melina_casadio · X

RT @Brunorm84: Spermidine is essential for #fasting-mediated #autophagy and #longevity @NatureCellBio https://t.co/jqntINULBO

Aug 9, 2024 · 12 shares · 1,300 followers View post →
Craig A. Goodman
@CraigAGoodman1 · X

RT @GGouspillou: Spermidine is essential for fasting-mediated autophagy and longevity | Nature Cell Biology https://t.co/gX3M0llrlO

Aug 9, 2024 · 6 shares · 3,894 followers View post →
Slawomir
@Slawomi18369321 · X

RT @agingdoc1: Spermidine is essential for fasting-mediated autophagy and longevity @seb_hofer and Frank Madeo https://t.co/5EmJBnPvDK ht…

Aug 9, 2024 · 6 shares · 84 followers View post →
Ordo Fraterna Fibonacci
@OrdoFibonacci · X

Spermidine is essential for fasting-mediated autophagy and longevity Nature https://t.co/biY8QNBzQV

Aug 9, 2024 · 2,567 followers View post →
M Fuensanta Martínez
@Mafuensanta · X

RT @Brunorm84: Spermidine is essential for #fasting-mediated #autophagy and #longevity @NatureCellBio https://t.co/jqntINULBO

Aug 9, 2024 · 12 shares · 2,454 followers View post →
Shima Taherkhani
@ShimaTaherkhani · X

RT @GGouspillou: Spermidine is essential for fasting-mediated autophagy and longevity | Nature Cell Biology https://t.co/gX3M0llrlO

Aug 9, 2024 · 6 shares · 352 followers View post →
Gilles Gouspillou
@GGouspillou · X

Spermidine is essential for fasting-mediated autophagy and longevity | Nature Cell Biology https://t.co/gX3M0llrlO

Aug 9, 2024 · 30 likes · 6 shares · 1,818 followers View post →
Amy Lamotte
@amylamotte88 · X

RT @Brunorm84: Spermidine is essential for #fasting-mediated #autophagy and #longevity @NatureCellBio https://t.co/jqntINULBO

Aug 9, 2024 · 12 shares · 259 followers View post →
Lisa Vlad
@LisaVlad2 · X

RT @agingdoc1: Spermidine is essential for fasting-mediated autophagy and longevity @seb_hofer and Frank Madeo https://t.co/5EmJBnPvDK ht…

Aug 9, 2024 · 6 shares · 102 followers View post →
Christophe Casalegno
@Brain0verride · X

RT @agingdoc1: Spermidine is essential for fasting-mediated autophagy and longevity @seb_hofer and Frank Madeo https://t.co/5EmJBnPvDK ht…

Aug 9, 2024 · 6 shares · 6,639 followers View post →
Dr L Boominathan PhD
@DrLBoominathan · X

RT @Brunorm84: Spermidine is essential for #fasting-mediated #autophagy and #longevity @NatureCellBio https://t.co/jqntINULBO

Aug 9, 2024 · 12 shares · 876 followers View post →
Raymond
@raymzyu · X

RT @Brunorm84: Spermidine is essential for #fasting-mediated #autophagy and #longevity @NatureCellBio https://t.co/jqntINULBO

Aug 9, 2024 · 12 shares · 105 followers View post →
Agingdoc
@agingdoc1 · X

Spermidine is essential for fasting-mediated autophagy and longevity @seb_hofer and Frank Madeo https://t.co/5EmJBnPvDK https://t.co/stbczMlj08

Aug 9, 2024 · 26 likes · 6 shares · 41,316 followers View post →
Bruno Ramos-Molina, PhD
@Brunorm84 · X

Spermidine is essential for #fasting-mediated #autophagy and #longevity @NatureCellBio https://t.co/jqntINULBO

Aug 9, 2024 · 47 likes · 12 shares · 6,433 followers View post →
Marina García Macia
@Juanaloca2002 · X

RT @cell_club: Spermidine is essential for fasting-mediated autophagy and longevity https://t.co/vAk89sUcPh

Aug 9, 2024 · 11 shares · 2,808 followers View post →
Abstream
@abstreamme · X

Spermidine is essential for fasting-mediated autophagy and longevity #science #publication #research #publications https://t.co/bjLovHVIax

Aug 9, 2024 · 788 followers View post →
Jinrong Hu
@HJRBio · X

RT @cell_club: Spermidine is essential for fasting-mediated autophagy and longevity https://t.co/vAk89sUcPh

Aug 9, 2024 · 11 shares · 411 followers View post →
Women in Autophagy
@WAutophagy · X

RT @cell_club: Spermidine is essential for fasting-mediated autophagy and longevity https://t.co/vAk89sUcPh

Aug 9, 2024 · 11 shares · 2,641 followers View post →
水炊きだいすき
@lovemizutaki · X

RT @cell_club: Spermidine is essential for fasting-mediated autophagy and longevity https://t.co/vAk89sUcPh

Aug 8, 2024 · 11 shares · 53 followers View post →
Bowen Wang
@NU_JEANSS · X

RT @cell_club: Spermidine is essential for fasting-mediated autophagy and longevity https://t.co/vAk89sUcPh

Aug 8, 2024 · 11 shares · 256 followers View post →
なんとかなるさ
@qRe50ZldkmjLkFI · X

RT @cell_club: Spermidine is essential for fasting-mediated autophagy and longevity https://t.co/vAk89sUcPh

Aug 8, 2024 · 11 shares · 47 followers View post →
Waclaw Koscielniak
@Vatsek · X

Spermidine is essential for fasting-mediated autophagy and longevity. https://t.co/7XEOHrn11H

Aug 8, 2024 · 2 likes · 7,126 followers View post →
Furkan E. Oflaz
@furkanEoflaz · X

RT @cell_club: Spermidine is essential for fasting-mediated autophagy and longevity https://t.co/vAk89sUcPh

Aug 8, 2024 · 11 shares · 172 followers View post →
nike
@wot_mikey · X

RT @cell_club: Spermidine is essential for fasting-mediated autophagy and longevity https://t.co/vAk89sUcPh

Aug 8, 2024 · 11 shares · 464 followers View post →
Enrique I. Oliver, Ph.D.
@EnriqueI_Oliver · X

RT @cell_club: Spermidine is essential for fasting-mediated autophagy and longevity https://t.co/vAk89sUcPh

Aug 8, 2024 · 11 shares · 478 followers View post →
Charles Jourdan Reyes, Ph.D.
@reyes_jourdan · X

RT @cell_club: Spermidine is essential for fasting-mediated autophagy and longevity https://t.co/vAk89sUcPh

Aug 8, 2024 · 11 shares · 626 followers View post →
wafy fahim
@wafyfahim1 · X

Spermidine is essential for fasting-mediated autophagy and longevity https://t.co/i9bcVbj4yI

Aug 8, 2024 · 1 like · 44 followers View post →
Cell Biology J-Club
@cell_club · X

Spermidine is essential for fasting-mediated autophagy and longevity https://t.co/vAk89sUcPh

Aug 8, 2024 · 34 likes · 11 shares · 6,090 followers View post →
Joel "Heart Prevention" Kahn MD, FACC
@drjkahn · X

Spermidine is essential for fasting-mediated autophagy and longevity | Nature Cell Biology - https://t.co/6Kx1bZDeyi

Aug 8, 2024 · 2 likes · 32,281 followers View post →