The collection of posts consistently emphasizes the significance of the FLOW trial, using phrases like 'substantially reduced risks' and 'significant reduction' to highlight the potential impact of semaglutide treatment on heart failure and cardiovascular outcomes. The tone, characterized by technical language and citations of specific statistics and analyses, underscores the high level of interest and perceived importance of this research within the medical community.
AgreementStrong agreement
Most discussions emphasize the positive effects of semaglutide, highlighting significant reductions in heart failure events and cardiovascular death, showing strong consensus support.
InterestHigh interest
The strong use of medical terminology, summaries of trial results, and references to specific analyses reflect high interest in the study's outcomes.
EngagementModerate engagement
While many discussions elaborate on the results, some posts merely share the findings or cite sources without much critical analysis, indicating moderate but not deep engagement.
ImpactHigh impact
The frequent references to structured clinical trials, statistical findings, and clinical implications demonstrate that these discussions are viewed as potentially transformative for medical practice.
Abstract in brief
People with type 2 diabetes and chronic kidney disease have a high risk of heart failure and cardiovascular death, making new treatments crucial.
The FLOW study found that semaglutide, a medication used for diabetes, significantly reduced severe kidney-related outcomes by 24% in participants with these conditions.
In a prespecified analysis, semaglutide also improved heart failure outcomes and reduced the risk of heart failure events and cardiovascular death over a median follow-up of 3.4 years compared to a placebo.
Con diabetes y enfermedad renal crónica G3A3, semaglutide 1.0mg semanal, comparado a placebo, ↓27% el evento cardiovascular y de falla cardiaca
Se necesitan tratar 34 pacientes para ver 1 beneficiado
En PostHoc del ensayo clínico FLOW
JACC 2024
10.1016/j.jacc.2024.08.004 https://t.co/4zgmFJGIsC
Oct 20, 2024 · 76 likes · 22 shares · 37,974 followersView post →
JJ
JACC Journals
@JACCJournals · X
FLOW trial: In participants with type 2 diabetes and chronic kidney disease, weekly semaglutide treatment substantially reduced risks of heart failure events or cardiovascular death. https://t.co/SaGx7tf0ie
#JACC #ESCCongress #HeartFailure #T2D #CKD #Semaglutide #CVD @RpratleyMD https://t.co/imPxyGPsiD
Aug 30, 2024 · 51 likes · 18 shares · 115,396 followersView post →
JJ
JACC Journals
@JACCJournals · X
#FLOW trial: In participants with type 2 #diabetes and #CKD, weekly #semaglutide treatment substantially reduced risks of #heartfailure events or CV death. https://t.co/OiUuD7Ryuz
#JACC #T2D #Obesity @RpratleyMD @KatherineTuttl8 https://t.co/jdW23vIqfY
Oct 19, 2024 · 31 likes · 17 shares · 115,396 followersView post →
TH
The Heart
@ZHeart11768530 · X
Oct 20, 2024 · 12 likes · 2 shares · 32,746 followersView post →
PR
Peter Rossing
@P_Rossing · X
Swe the amazing Effects of Semaglutide on Heart Failure Outcomes in Diabetes and CKD https://t.co/kowNb62ye4 @Stenodiabetes https://t.co/PQDeDsMYhP
Aug 30, 2024 · 12 likes · 2 shares · 1,528 followersView post →
AM
Ahmed Bennis MD
@drbennisahmed · X
Effects of Semaglutide on Heart Failure Outcomes in Diabetes and CKD FLOW Trial
Semaglutide reduced the risk of time to first composite outcome of HF events or CV death, as well as HF events and CV death alone, in high-risk population with T2D and CKD
https://t.co/3UulKvZ2U5 https://t.co/bFxef1rRfr
Oct 20, 2024 · 10 likes · 2 shares · 3,159 followersView post →
Emerging evidence indicates that semaglutide, a treatment for type 2 diabetes, may protect against Alzheimer's disease, but more real-world data are needed. The study compared effects of semaglutide against other…
Neha J Pagidipati MD FACC and Richard Pratley MD discuss how the FLOW trial demonstrates that semaglutide significantly reduces heart failure events, cardiovascular death, and kidney failure in patients with diabetes…
4/ ❤️Semaglutide Reduces HF Events
In T2D + CKD (FLOW), weekly sema ↓ HF events by 27% and CV death by 29%.
✅Benefits seen regardless of prior HF history.
أظهرت تجربة FLOW أن Semaglutide قد يحسن نتائج فشل القلب في مرضى السكري ومرض الكلى المزمن. #صحة_القلب #السكري #مرض_الكلى https://t.co/SgKiAMlKQM https://t.co/rYuTtEiE2N
(3/7) In #JACC, Dr. @RpratleyMD and colleagues published a secondary analysis of FLOW looking at #semaglutide's impact on #heartfailure outcomes in this population
https://t.co/NBXW1RBqQy https://t.co/eHAfJni5WX
Jan 9, 2025 · 1 like · 115,396 followersView post →
A
ana
@wIwbot · X
Effects of Semaglutide on Heart Failure Outcomes in Diabetes and Chronic Kidney Disease in the FLOW Trial | Journal of the American College of Cardiology https://t.co/XdAQuVW9Bi
RT @JonathanNefro: Con diabetes y enfermedad renal crónica G3A3, semaglutide 1.0mg semanal, comparado a placebo, ↓27% el evento cardiovascu…
Oct 20, 2024 · 22 shares · 252 followersView post →
C
Carlos
@de_montecristo · X
RT @JonathanNefro: Con diabetes y enfermedad renal crónica G3A3, semaglutide 1.0mg semanal, comparado a placebo, ↓27% el evento cardiovascu…
Oct 20, 2024 · 22 shares · 2,735 followersView post →
VP
Villahermosa se vistió de fiesta con la primavera
@Gust_1971 · X
RT @JonathanNefro: Con diabetes y enfermedad renal crónica G3A3, semaglutide 1.0mg semanal, comparado a placebo, ↓27% el evento cardiovascu…
Oct 20, 2024 · 22 shares · 502 followersView post →
J
jomincp
@jomincp · X
RT @JonathanNefro: Con diabetes y enfermedad renal crónica G3A3, semaglutide 1.0mg semanal, comparado a placebo, ↓27% el evento cardiovascu…
Oct 20, 2024 · 22 shares · 10 followersView post →
SH
soda_troubles,https://med-mastodon.com/@haysam
@set_fortess · X
RT @JonathanNefro: Con diabetes y enfermedad renal crónica G3A3, semaglutide 1.0mg semanal, comparado a placebo, ↓27% el evento cardiovascu…
Oct 20, 2024 · 22 shares · 2,594 followersView post →
FM
Freddy Shanner, MD
@FreddyShanner · X
RT @JonathanNefro: Con diabetes y enfermedad renal crónica G3A3, semaglutide 1.0mg semanal, comparado a placebo, ↓27% el evento cardiovascu…
Oct 20, 2024 · 22 shares · 322 followersView post →
DE
Dr. Hugo Corrales - Endocrinología.
@hugoendocrino · X
RT @JonathanNefro: Con diabetes y enfermedad renal crónica G3A3, semaglutide 1.0mg semanal, comparado a placebo, ↓27% el evento cardiovascu…
Oct 20, 2024 · 22 shares · 6,478 followersView post →
AK
A K
@annafval · X
RT @JonathanNefro: Con diabetes y enfermedad renal crónica G3A3, semaglutide 1.0mg semanal, comparado a placebo, ↓27% el evento cardiovascu…
Oct 20, 2024 · 22 shares · 203 followersView post →
SV
Sebastián Tenorio Vargas
@SebasTenorio · X
RT @JonathanNefro: Con diabetes y enfermedad renal crónica G3A3, semaglutide 1.0mg semanal, comparado a placebo, ↓27% el evento cardiovascu…
Oct 20, 2024 · 22 shares · 534 followersView post →
JE
Juan Carlos Elizalde:.
@JuanElizalde777 · X
RT @JonathanNefro: Con diabetes y enfermedad renal crónica G3A3, semaglutide 1.0mg semanal, comparado a placebo, ↓27% el evento cardiovascu…
Oct 20, 2024 · 22 shares · 2,397 followersView post →
DA
Dr. ALCupich
@alcupich · X
RT @JonathanNefro: Con diabetes y enfermedad renal crónica G3A3, semaglutide 1.0mg semanal, comparado a placebo, ↓27% el evento cardiovascu…
Oct 20, 2024 · 22 shares · 562 followersView post →
M
María.
@callmevaaal · X
RT @JonathanNefro: Con diabetes y enfermedad renal crónica G3A3, semaglutide 1.0mg semanal, comparado a placebo, ↓27% el evento cardiovascu…
Oct 20, 2024 · 22 shares · 591 followersView post →
DN
Dr. Ronald Caraballo NEFROLOGO
@ronald_nefro · X
RT @JonathanNefro: Con diabetes y enfermedad renal crónica G3A3, semaglutide 1.0mg semanal, comparado a placebo, ↓27% el evento cardiovascu…
Oct 20, 2024 · 22 shares · 664 followersView post →
JC
Jonathan Chávez
@JonathanNefro · X
Con diabetes y enfermedad renal crónica G3A3, semaglutide 1.0mg semanal, comparado a placebo, ↓27% el evento cardiovascular y de falla cardiaca
Se necesitan tratar 34 pacientes para ver 1 beneficiado
En PostHoc del ensayo clínico FLOW
JACC 2024
10.1016/j.jacc.2024.08.004 https://t.co/4zgmFJGIsC
Oct 20, 2024 · 76 likes · 22 shares · 37,974 followersView post →
JR
juan ramon
@RamonTasmania · X
RT @drbennisahmed: Effects of Semaglutide on Heart Failure Outcomes in Diabetes and CKD FLOW Trial
Semaglutide reduced the risk of time t…
Oct 20, 2024 · 2 shares · 452 followersView post →
TH
The Heart
@ZHeart11768530 · X
Oct 20, 2024 · 12 likes · 2 shares · 32,746 followersView post →
UC
UKCPA Cardiovascular Committee
@UKCPACardiac · X
RT @drbennisahmed: Effects of Semaglutide on Heart Failure Outcomes in Diabetes and CKD FLOW Trial
Semaglutide reduced the risk of time t…
Oct 20, 2024 · 2 shares · 758 followersView post →
AM
Ahmed Bennis MD
@drbennisahmed · X
Effects of Semaglutide on Heart Failure Outcomes in Diabetes and CKD FLOW Trial
Semaglutide reduced the risk of time to first composite outcome of HF events or CV death, as well as HF events and CV death alone, in high-risk population with T2D and CKD
https://t.co/3UulKvZ2U5 https://t.co/bFxef1rRfr
Oct 20, 2024 · 10 likes · 2 shares · 3,159 followersView post →
DL
| Daniel Sierra LM |
@DanielSierraLM · X
RT @JACCJournals: #FLOW trial: In participants with type 2 #diabetes and #CKD, weekly #semaglutide treatment substantially reduced risks of…
Oct 19, 2024 · 17 shares · 2,489 followersView post →
Tね
Takuya Kishi @ねこ好き循環器内科医
@tkishi_cardiol · X
RT @JACCJournals: #FLOW trial: In participants with type 2 #diabetes and #CKD, weekly #semaglutide treatment substantially reduced risks of…
Oct 19, 2024 · 17 shares · 14,915 followersView post →
EE
Elham Elmehdawi
@Elham1549664 · X
RT @JACCJournals: #FLOW trial: In participants with type 2 #diabetes and #CKD, weekly #semaglutide treatment substantially reduced risks of…
Oct 19, 2024 · 17 shares · 43 followersView post →
糸潤
糸長 潤平
@jumpei_0217 · X
RT @JACCJournals: #FLOW trial: In participants with type 2 #diabetes and #CKD, weekly #semaglutide treatment substantially reduced risks of…
Oct 19, 2024 · 17 shares · 104 followersView post →
CM
ChonyAlbert MD
@ChonyAlbertMD · X
RT @JACCJournals: #FLOW trial: In participants with type 2 #diabetes and #CKD, weekly #semaglutide treatment substantially reduced risks of…
Oct 19, 2024 · 17 shares · 948 followersView post →
JF
Josh Ronen, MD, FACP
@jronenMD · X
RT @JACCJournals: #FLOW trial: In participants with type 2 #diabetes and #CKD, weekly #semaglutide treatment substantially reduced risks of…
Oct 19, 2024 · 17 shares · 127 followersView post →
JJ
JACC Journals
@JACCJournals · X
#FLOW trial: In participants with type 2 #diabetes and #CKD, weekly #semaglutide treatment substantially reduced risks of #heartfailure events or CV death. https://t.co/OiUuD7Ryuz
#JACC #T2D #Obesity @RpratleyMD @KatherineTuttl8 https://t.co/jdW23vIqfY
Oct 19, 2024 · 31 likes · 17 shares · 115,396 followersView post →
SC
SFC - Société Française de Cardiologie
@SFCardio · X
Effects of Semaglutide on Heart Failure Outcomes in Diabetes and Chronic Kidney Disease in the FLOW Trial
Aug 30, 2024 · 7 likes · 1 share · 32,746 followersView post →
S
susanconnolly
@susanbconnolly · X
RT @JACCJournals: FLOW trial: In participants with type 2 diabetes and chronic kidney disease, weekly semaglutide treatment substantially r…
Aug 30, 2024 · 18 shares · 1,693 followersView post →
DC
David González Calle
@davidcalle1390 · X
RT @JACCJournals: FLOW trial: In participants with type 2 diabetes and chronic kidney disease, weekly semaglutide treatment substantially r…
Aug 30, 2024 · 18 shares · 9,208 followersView post →
PC
Prof Derek Connolly
@DrDerekConnolly · X
RT @JACCJournals: FLOW trial: In participants with type 2 diabetes and chronic kidney disease, weekly semaglutide treatment substantially r…
Aug 30, 2024 · 18 shares · 3,953 followersView post →
RM
Richard Pratley MD
@RpratleyMD · X
Effects of Semaglutide on Heart Failure Outcomes in Diabetes and Chron... https://t.co/AUhIPS78jh
Just presented at #ESC and published in #JACC - semaglutide decreased risk of heart failure and CV death by 27% in the FLOW trial in T2D and CVD.
RT @JACCJournals: FLOW trial: In participants with type 2 diabetes and chronic kidney disease, weekly semaglutide treatment substantially r…
Aug 30, 2024 · 18 shares · 693 followersView post →
PR
Peter Rossing
@P_Rossing · X
Swe the amazing Effects of Semaglutide on Heart Failure Outcomes in Diabetes and CKD https://t.co/kowNb62ye4 @Stenodiabetes https://t.co/PQDeDsMYhP
Aug 30, 2024 · 12 likes · 2 shares · 1,528 followersView post →
SZ
Shelley Zieroth
@ShelleyZieroth · X
RT @JACCJournals: FLOW trial: In participants with type 2 diabetes and chronic kidney disease, weekly semaglutide treatment substantially r…
Aug 30, 2024 · 18 shares · 10,015 followersView post →
BN
Brendon Neuen
@brendonneuen · X
RT @JACCJournals: FLOW trial: In participants with type 2 diabetes and chronic kidney disease, weekly semaglutide treatment substantially r…
Aug 30, 2024 · 18 shares · 4,697 followersView post →
JJ
JACC Journals
@JACCJournals · X
FLOW trial: In participants with type 2 diabetes and chronic kidney disease, weekly semaglutide treatment substantially reduced risks of heart failure events or cardiovascular death. https://t.co/SaGx7tf0ie
#JACC #ESCCongress #HeartFailure #T2D #CKD #Semaglutide #CVD @RpratleyMD https://t.co/imPxyGPsiD
Aug 30, 2024 · 51 likes · 18 shares · 115,396 followersView post →
N
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