Aging Cell January 2025 PMID 39319670

A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring.

Todd W Dowrey, Samuel F Cranston, Nicholas Skvir, Yvonne Lok, Brian Gould, Bradley Petrowitz, Daniel Villar, Jidong Shan, Marianne James, Mark Dodge, Anna C Belkina, Richard M Giadone, Sofiya Milman, Paola Sebastiani, Thomas T Perls

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Peak: 11 in Sep 2024

across 7 sources since Mar 2024

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186,667

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107

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Mar 2024 – Feb 2025

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AI synopsis

What people are saying

Discussions around the publication emphasize its role as a pioneering resource for studying healthy aging and resilience, with phrases like 'unique resource' and 'advances the field.' Several posters highlight the significance of blood samples from centenarians and the potential for discovering therapies, demonstrating both interest and recognition of its impact. The tone suggests admiration for the research's innovative approach and potential future influence, though some commentary remains at a descriptive or supportive level rather than deeply critical or questioning.

AgreementModerate agreement

Most discussions recognize the importance and potential of creating a bank of stem cells from centenarians for aging research, indicating general support and acknowledgment.

InterestHigh interest

The frequent mention of the research’s relevance to longevity, aging, and therapeutics shows a high level of curiosity and focus from the audience.

EngagementModerate engagement

Several posts highlight specific elements, such as the methodology of reprogramming blood cells and the significance for understanding aging resistance, demonstrating some depth of engagement.

ImpactModerate impact

While the discussions underline the significance of the resource for aging studies, they mainly frame it as a valuable research tool rather than implying immediate practical applications, resulting in a moderate perception of impact.

Abstract in brief

The study focuses on creating a special bank of induced pluripotent stem cells (iPSCs) from centenarians and their children to better understand healthy aging, resilience, and longevity, since such human aging models are rare.
Researchers collected and analyzed blood samples from over 96 individuals, including data on their functional independence and resistance to disability and cognitive decline, using molecular aging clocks based on methylation patterns.
From these samples, they successfully reprogrammed blood cells into high-quality iPSC lines, which can be used to study aging and test potential treatments for age-related diseases.]

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All mentions

Understanding Longevity Through Stem Cell Research and Aging Models

The study focuses on creating a special bank of induced pluripotent stem cells from centenarians and their children to better understand healthy aging, resilience, and longevity. Researchers analyzed blood samples from…

Dr. O · Nov 10, 2024 62 views

Advancing Longevity Research with Stem Cells from Centenarians

The video explores creating a bank of induced pluripotent stem cells from centenarians and their offspring to understand healthy aging, resilience, and longevity. It discusses molecular aging clocks and the potential…

Dr. O · Nov 10, 2024 24 views

Understanding Longevity Through Stem Cell Research in Centenarians

The video explores a new approach supported by science to understand healthy aging and increase chances of living beyond 100. It discusses a specialized bank of induced pluripotent stem cells from centenarians and their…

Dr. O · Nov 10, 2024 21 views

Bowen Wang

@NU_JEANSS · X

RT @agingdoc1: A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring https://t.co/AFqYykFWuW…

Feb 9, 2025 · 2 shares · 260 followers View post →

Einstein Nathan Shock Center of Excellence

@EinsteinAging · X

RT @agingdoc1: A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring https://t.co/AFqYykFWuW…

Feb 9, 2025 · 2 shares · 472 followers View post →

Agingdoc

@agingdoc1 · X

A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring https://t.co/AFqYykFWuW @Aging_Cell https://t.co/3ti5VstbaY

Feb 9, 2025 · 15 likes · 2 shares · 41,647 followers View post →

AI_4_Healthcare

@AI_4_Healthcare · X

By looking at blood samples from centenarians, scientists are learning how 100-year-olds resist disability and memory loss. They made special #stemcell lines to further study #aging. This research advances the field of #longevity. HT @PeterDiamandis https://t.co/wQL1k4qt6U

Jan 8, 2025 · 2 likes · 1,626 followers View post →

Ian W. Yeo

@IanYeo · X

A longevity‐specific bank of induced pluripotent stem cells from centenarians and their offspring - Dowrey - Aging Cell - Wiley Online Library https://t.co/nWyXC5B9sI

Jan 5, 2025 · 113 followers View post →

Longevity

@LongevityTao · X

A longevity‐specific bank of induced pluripotent stem cells from centenarians and their offspring - Dowrey - Aging Cell - Wiley Online Library https://t.co/rZaZ4DrMjy

Oct 7, 2024 · 1 like · 331 followers View post →

Feng-Yung Wang

@FengYungWang1 · X

RT @DowreyTodd: Out now in @AgingCell! Our work detailing a longevity-specific bank of PBMCs and resultant iPSC lines from #centenarians an…

Oct 3, 2024 · 6 shares · 95 followers View post →

Alexander Dakhovnik

@ADakhovnik · X

RT @AgingBiology: A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring https://t.co/reZKWBYdtN

Oct 2, 2024 · 9 shares · 77 followers View post →

Lisa Vlad

@LisaVlad2 · X

RT @AgingBiology: A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring https://t.co/reZKWBYdtN

Oct 1, 2024 · 9 shares · 108 followers View post →

INSPIRE Platform - IHU HealthAge

@INSPIREPlatfor1 · X

A unique lens to study longevity, healthy aging, and resiliency in "A longevity‐specific bank of induced pluripotent stem cells from centenarians and their offspring" https://t.co/QMSwHQdCog @brunovellas @isaperarnau @InfinityTLS @RestoreInstitut @I2mcT @

Oct 1, 2024 · 674 followers View post →

Agingdoc

@agingdoc1 · X

Oct 1, 2024 · 4 likes · 41,647 followers View post →

Kujon Naukowski

@Nerd_kujon · X

RT @AgingBiology: A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring https://t.co/reZKWBYdtN

Oct 1, 2024 · 9 shares · 33 followers View post →

AngryPhDstudent❗️❗️❗️

@ONNESHA092 · X

RT @AgingBiology: A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring https://t.co/reZKWBYdtN

Oct 1, 2024 · 9 shares · 183 followers View post →

John Greene

@Greene_Thoughts · X

RT @AgingBiology: A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring https://t.co/reZKWBYdtN

Sep 30, 2024 · 9 shares · 1,699 followers View post →

Ahmed Ibrahim

@TheIbrahimLab · X

RT @AgingBiology: A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring https://t.co/reZKWBYdtN

Sep 30, 2024 · 9 shares · 605 followers View post →

Lucas Schoenfeldt

@schlucas_ · X

RT @AgingBiology: A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring https://t.co/reZKWBYdtN

Sep 30, 2024 · 9 shares · 75 followers View post →

Victoria VALPARAISO

@Orange_Atomique · X

RT @AgingBiology: A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring https://t.co/reZKWBYdtN

Sep 30, 2024 · 9 shares · 180 followers View post →

Aging Science News

@AgingBiology · X

A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring https://t.co/reZKWBYdtN

Sep 30, 2024 · 30 likes · 9 shares · 30,585 followers View post →

Pushpinder Bawa

@PushpinderBawa · X

RT @DowreyTodd: Out now in @AgingCell! Our work detailing a longevity-specific bank of PBMCs and resultant iPSC lines from #centenarians an…

Sep 29, 2024 · 6 shares · 112 followers View post →

Darrell Kotton

@Kottond · X

RT @DowreyTodd: Out now in @AgingCell! Our work detailing a longevity-specific bank of PBMCs and resultant iPSC lines from #centenarians an…

Sep 29, 2024 · 6 shares · 1,862 followers View post →

Nicholas S

@nskvir_phd · X

RT @DowreyTodd: Out now in @AgingCell! Our work detailing a longevity-specific bank of PBMCs and resultant iPSC lines from #centenarians an…

Sep 26, 2024 · 6 shares · 14 followers View post →

George J. Murphy

@DrGJMurphy · X

RT @DowreyTodd: Out now in @AgingCell! Our work detailing a longevity-specific bank of PBMCs and resultant iPSC lines from #centenarians an…

Sep 26, 2024 · 6 shares · 730 followers View post →

Jesse Poganik

@jpoganik · X

RT @DowreyTodd: Out now in @AgingCell! Our work detailing a longevity-specific bank of PBMCs and resultant iPSC lines from #centenarians an…

Sep 26, 2024 · 6 shares · 458 followers View post →

Todd Dowrey

@DowreyTodd · X

Out now in @AgingCell! Our work detailing a longevity-specific bank of PBMCs and resultant iPSC lines from #centenarians and their offspring. https://t.co/Nn6rlXF9kD

Sep 26, 2024 · 13 likes · 6 shares · 165 followers View post →

Deepal Ekanayake, MD

@DrDeepal1 · X

#LONGEVITY #longevityresearch #stemcells #centenarians A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring https://t.co/A6GrRSILXE

Jul 20, 2024 · 1,031 followers View post →

System

@liyongcsco12 · X

RT @agingdoc1: A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring @DowreyTodd, @DrGJMurphy…

Apr 8, 2024 · 2 shares · 64 followers View post →

George J. Murphy

@DrGJMurphy · X

RT @agingdoc1: A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring @DowreyTodd, @DrGJMurphy…

Apr 7, 2024 · 2 shares · 730 followers View post →

Agingdoc

@agingdoc1 · X

A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring @DowreyTodd, @DrGJMurphy https://t.co/Zwqi33wrOd https://t.co/0rdvr3V2lh

Apr 7, 2024 · 10 likes · 2 shares · 41,647 followers View post →

Daniel Cortés

@edcortes22 · X

RT @martinperaJAX: A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring https://t.co/3l5usJoFkZ

Mar 15, 2024 · 3 shares · 63 followers View post →

Norio Nakatsuji

@norionakatsuji · X

RT @martinperaJAX: A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring https://t.co/3l5usJoFkZ

Mar 14, 2024 · 3 shares · 15,700 followers View post →

Martin Pera

@martinperaJAX · X

A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring https://t.co/3l5usJoFkZ

Mar 14, 2024 · 7 likes · 3 shares · 2,380 followers View post →

SciencesNetwork

@SciencesNetwork · X

A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring https://t.co/1cpQVXUgkF

Mar 14, 2024 · 349 followers View post →

bioRxiv Molecular Biology

@biorxiv-molbio.bsky.social · Bluesky

A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring https://www.biorxiv.org/content/10.1101/2024.03.12.584663v1

Mar 14, 2024 View post →

bioRxivpreprint

@biorxivpreprint.bsky.social · Bluesky

A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring https://www.biorxiv.org/content/10.1101/2024.03.12.584663v1

Mar 14, 2024 View post →

bioRxiv Molecular Biology

@biorxiv_molbio · X

A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring https://t.co/2kdwsJGnxW #biorxiv_molbio

Mar 14, 2024 · 558 followers View post →

A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Understanding Longevity Through Stem Cell Research and Aging Models

Advancing Longevity Research with Stem Cells from Centenarians

Understanding Longevity Through Stem Cell Research in Centenarians