A Machine Learning-Optimized System for Pulsatile, Photo- and Chemotherapeutic Treatment Using Near-Infrared Responsive MoS-Based Microparticles in a Breast Cancer Model.

Maria Kanelli, Neelkanth M Bardhan, Morteza Sarmadi, Behnaz Eshaghi, Shahad K Alsaiari, William T Rothwell, Apurva Pardeshi, Dhruv Varshney, Dominique C De Fiesta, Howard Mak, Virginia Spanoudaki, Nicole Henning, Ashutosh Kumar, Jooli Han, Angela M Belcher

November 2024 ACS Nano

Synopsis of Social media discussions

Discussions consistently praise the article's innovative approach, highlighting phrases like 'game-changing' and 'completely eradicates tumors,' reflecting strong enthusiasm. The tone, supported by technical references and mentions of reduced side effects, underscores a recognition of its potential to revolutionize cancer therapy and influence ongoing research.

A
Agreement
 Strong agreement

All discussions express strong support and excitement for the research, frequently calling it 'game-changing' and emphasizing its potential in cancer therapy.

I
Interest
 High level of interest

The topics generate high interest, with many posts highlighting innovative aspects like the use of machine learning and near-infrared responsive microparticles.

E
Engagement
 High engagement

Posts show deep engagement by referencing specific methods, such as pulsatile delivery, thermal ablation, and systemic toxicity reduction, demonstrating thorough understanding and interest.

I
Impact
 High level of impact

The overall tone suggests that users believe this development could significantly influence future cancer treatments and inspire further research, indicating high perceived impact.

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YouTube

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Bluesky

1 Posts

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238,359

Total Likes

7,898

Extended Reach

423,604

Social Features

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Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

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  • Ivan Vidal (Van-rito Ullij)
    @nanoLaniakea (Twitter)

    RT @kochinstitute: Cancer treatment, upgraded. Tiny implantable microparticles deliver chemo & heat therapy directly to tumors, reducing si…
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    March 4, 2025

    3

  • Koch Institute at MIT
    @kochinstitute (Twitter)

    Cancer treatment, upgraded. Tiny implantable microparticles deliver chemo & heat therapy directly to tumors, reducing side effects. Vote for this #STATMadness entry - Group 2, Matchup 6: https://t.co/cMWdrhlTqO
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    March 4, 2025

    7

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  • Reiner 
    @erlesen (Twitter)

    RT @erlesen: A Machine Learning-Optimized System for Pulsatile, Photo- and Chemotherapeutic Treatment https://t.co/CZa8Joloen Game-Changing…
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    January 8, 2025

    1

  • Dr Singularity
    @Dr_Singularity (Twitter)

    more here https://t.co/rGNe4F4z02 and here https://t.co/wIO7yznoC7
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    December 24, 2024

    4

  • Ariel R Abramovsky
    @realAriel_A (Twitter)

    https://t.co/965Q6cuO4c
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    December 23, 2024

  • Reiner
    @erlangen.bsky.social (Bluesky)

    A Machine Learning-Optimized System for Pulsatile, Photo- and Chemotherapeutic Treatment pubs.acs.org/doi/10.1021/... Game-Changing Dual Cancer Therapy Completely Eradicates Tumors Without Harsh Side Effects scitechdaily.com/game-changin... This synergistic effect results in lower systemic toxicity
    view full post

    December 21, 2024

    1

  • Reiner 
    @erlesen (Twitter)

    A Machine Learning-Optimized System for Pulsatile, Photo- and Chemotherapeutic Treatment https://t.co/CZa8Joloen Game-Changing Dual Cancer Therapy Completely Eradicates Tumors Without Harsh Side Effects https://t.co/nO3qfgDiJ0 Synergistic effect results in lower systemic toxicity
    view full post

    December 21, 2024

    2

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  • Chidambara .ML.
    @chidambara09 (Twitter)

    https://t.co/d0JKATuprI
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    November 4, 2024

  • Machine Learning in Chemistry
    @ML_Chem (Twitter)

    A Machine Learning-Optimized System for Pulsatile, Photo- and Chemotherapeutic Treatment Using Near-Infrared Responsive MoS2-Based Microparticles in a Breast Cancer Model #machinelearning #compchem https://t.co/OhkaVODpXQ
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    November 4, 2024

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  • Tom Varghese Jr. MD, MS, MBA, FACS, MAMSE
    @TomVargheseJr (Twitter)

    RT @ScottSAmyx: A Machine Learning-Optimized System for Pulsatile, Photo- and Chemotherapeutic Treatment Using Near-Infrared Responsive MoS…
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    October 30, 2024

    1

  • Scott Amyx
    @ScottSAmyx (Twitter)

    A Machine Learning-Optimized System for Pulsatile, Photo- and Chemotherapeutic Treatment Using Near-Infrared Responsive MoS2-Based Microparticles in a Breast Cancer Model | ACS Nano https://t.co/9NUZZZm0GR
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    October 30, 2024

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  • Free56
    @Free5620 (Twitter)

    RT @Free5620: https://t.co/ZGfZrDS4U3 https://t.co/SyLFsSFbWu. https://t.co/Jh7aJvL1f0
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    October 29, 2024

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  • Free56
    @Free5620 (Twitter)

    https://t.co/ZGfZrDS4U3 https://t.co/SyLFsSFbWu. https://t.co/Jh7aJvL1f0
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    October 29, 2024

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  • Chidambara .ML.
    @chidambara09 (Twitter)

    https://t.co/s9McPKcpBi
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    October 28, 2024

  • Epic Plain
    @EpicPlain (Twitter)

    A Machine Learning-Optimized System for Pulsatile, Photo- and Chemotherapeutic ... https://t.co/HLALMwhBxe #MachineLearning
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    October 28, 2024

Abstract Synopsis

  • The study developed a light-activated microparticle system made of polycaprolactone containing MoS2 nanosheets and anticancer drugs, enabling localized, pulsatile delivery combined with thermal ablation when exposed to near-infrared laser light.
  • A machine learning algorithm was used to optimize the laser treatment conditions, improving the efficiency of the therapy, which was tested in mice with breast cancer tumors, showing significant tumor eradication and increased survival rates.
  • This approach offers a minimally invasive and precisely targeted treatment option suitable for recurring cycles, reducing side effects and overcoming resistance seen with traditional cancer therapies.]