Eur Neuropsychopharmacol January 2025 PMID 39488067

Efficacy and safety profile of oral creatine monohydrate in add-on to cognitive-behavioural therapy in depression: An 8-week pilot, double-blind, randomised, placebo-controlled feasibility and exploratory trial in an under-resourced area.

Nima Norbu Sherpa, Riccardo De Giorgi, Edoardo Giuseppe Ostinelli, Amrita Choudhury, Tenzin Dolma, Sangila Dorjee

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AI synopsis

What people are saying

Numerous discussions highlight the advantages of adding creatine to cognitive-behavioral therapy, with phrases like 'superior to CBT alone' and 'feasible intervention in under-resourced areas' reflecting enthusiasm for its potential applications. The tone of these discussions is largely optimistic, emphasizing the safe nature of creatine and its well-researched background, which contributes to a sense of hope regarding new treatment strategies.

AgreementModerate agreement

There is general support for the study's conclusions regarding the benefits of creatine in aiding depression treatment.

InterestHigh interest

The topic has generated considerable curiosity, as many participants are exploring the implications of combining creatine with cognitive behavioral therapy.

EngagementModerate engagement

While discussions vary in depth, many participants analyze the study methods and express personal opinions about integrating creatine with conventional therapy.

ImpactHigh impact

Many users perceive this research as having a significant positive influence on treatment options for depression.

Abstract in brief

Creatine monohydrate may enhance the effects of cognitive-behavioral therapy (CBT) in treating depression, as suggested by pre-clinical and clinical research.
In an 8-week study with 100 participants, combining creatine with CBT led to a significantly greater decrease in depression scores compared to a placebo with CBT.
The study found no significant differences in dropout rates or adverse events between the creatine and placebo groups, indicating that creatine is a safe adjunct to traditional depression treatment.

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Riccardo De Giorgi

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Linked study: https://t.co/IcaOOsJBNy

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Link to the study: pubmed.ncbi.nlm.nih.gov/39488067/

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RT @daridor: https://t.co/HXARuQbeSP

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https://t.co/HXARuQbeSP

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Efficacy and safety profile of oral creatine monohydrate in add-on to cognitive-behavioural therapy in depression: An 8-week pilot, double-blind, randomised, placebo-controlled feasibility and exploratory trial in an under-resourced area - PubMed https://t.co/cmblgG0JKm

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drehman ☕️#ReadWriteThinkCriticallyDaily

@pomdr · X

compared to the placebo group. —The Daily Pump @Schwarzenegger @BornFitness @ketch https://t.co/D3bD1AXnvy

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Fuente: https://t.co/ZVcOu2SbIP

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Detalle: https://t.co/h80xwO8a4E

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https://t.co/35hCeS7exM

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Efficacy and safety profile of oral creatine monohydrate in add-on to cognitive-behavioural therapy (CBT) in depression www.sciencedirect.com/science/arti... The combination of the inexpensive nutraceutical, creatine with CBT for depressive disorder is a feasible intervention

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@joellewin.bsky.social · Bluesky

Creatine + CBT!? Sending all those brain training metaphors into overdrive pubmed.ncbi.nlm.nih.gov/39488067/

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Efficacy and safety profile of oral creatine monohydrate in add-on to cognitive-behavioural therapy in depression: An 8-week pilot, double-blind, randomised, placebo-controlled feasibility and exploratory trial in an under-resourced area.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

The Role of Creatine in Enhancing Depression Treatment

Exploring Creatine's Potential in Depression Treatment with Dr. Fabiano

Creatine's Role in Enhancing Cognitive Behavioral Therapy for Depression

Dr. Riccardo De Giorgi: Connecting Metabolic and Mental Health, GLP-1 Drugs, Depression and Hope

Creatine and Brain Performance: Effects on Memory and Focus

Impact of Training Volume and Creatine on Mental Well-being in Youths

Magnesium Supplementation's Impact on Mental Health Treatment