December 2024 PMID 39532305

Generating Tooth Organoids Using Defined Bioorthogonally Cross-Linked Hydrogels.

Xuechen Zhang, Nicola Contessi Negrini, Rita Correia, Paul T Sharpe, Adam D Celiz, Ana Angelova Volponi

Mentions

277
Peak: 7 in Apr 2025
across 5 sources since Nov 2024

Extended reach

66,339
potential audience

Total likes

75

Video views

4,098

Mentions per month

Nov 2024 – May 2025

Where it's discussed

  • News254 articles
  • X / Twitter13 posts
  • Blogs6 articles
  • Bluesky2 posts
  • YouTube2 videos

AI synopsis

What people are saying

The collective discussions emphasize the promising future of lab-grown teeth, with phrases like 'game-changing' and 'breakthrough' reflecting excitement and significance. Posts mentioning innovations like using stem cells for natural replacements and specific references to the methodology indicate both enthusiasm and recognition of the research’s transformative potential.

AgreementStrong agreement

Most discussions express strong support and enthusiasm for the research, highlighting its potential to revolutionize dental treatments and recognition of the scientific breakthrough.

InterestHigh interest

The posts show high curiosity and excitement about growing teeth in the lab and its medical implications, indicating strong engagement with the topic.

EngagementHigh engagement

Many users discuss scientific details, potential medical applications, and future possibilities, demonstrating active and deep engagement.

ImpactHigh impact

The discussions suggest the research could significantly influence dentistry by providing durable, rejection-free alternatives, thus indicating high potential impact.

Abstract in brief

  • Generating teeth involves replicating developmental processes with the help of biomaterials that support 3D tooth organoid formation.
  • Researchers utilized bioorthogonally cross-linked hydrogels, adjusting their properties to optimize biomimicry for tooth development, focusing on specific gelatin concentrations and ratios of modifying agents.
  • They successfully identified a hydrogel formulation that allowed for effective growth and shaping of tooth germs, creating a versatile platform for further tooth organoid engineering and research.

Top posts

Most liked on X and Bluesky
Celiz Lab
@celizlab · X

Check out our latest paper in @ACSMacroLett on defined hydrogels for tooth organoid formation. Great collaboration with @kingsdentistry. @ContessiNicola @ImperialBioeng https://t.co/vOF9zWWVcO

Nov 14, 2024 · 19 likes · 5 shares · 779 followers View post →
Candi (No
@acabchick.bsky.social · Bluesky

#Lab #Grown #Teeth #Breakthrough #Research Detailed research info. at below #NIH #NLM link. pubmed.ncbi.nlm.nih.gov/39532305/

Apr 24, 2025 · 8 likes · 2 shares View post →
polvo
@coprodu.to · Bluesky

Mas há outras possibilidades interessantes com transplantes autólogos. Uma que li recentemente um artigo sobre e achei bem legal seria de clonar *dentes* pra pessoas que tenham perdido em acidentes, por exemplo. pubmed.ncbi.nlm.nih.gov/39532305/

Apr 30, 2025 · 3 likes · 1 share View post →
Dr. Shahid Aziz
@Shahid_cl · X

Lab-grown teeth would naturally regenerate, integrating into the jaw as real teeth. Stronger, longer-lasting, and free from rejection risks, offering a more durable and biologically compatible solution than filling or implants. @KingsCollegeLon DOI: 10.1021/acsmacrolett.4c00520 https://t.co/VHyHzG6d97

May 3, 2025 · 2 likes · 939 followers View post →
el hombre pulpo
@coproduto · X

Mas há outras possibilidades interessantes com transplantes autólogos. Uma que li recentemente um artigo sobre e achei bem legal seria de clonar *dentes* pra pessoas que tenham perdido em acidentes, por exemplo. https://t.co/PahS0urgit

Apr 30, 2025 · 1 like · 22,129 followers View post →
Stem Cell Foundation
@AusStemCell · X

‘Lab-grown teeth could offer alternative to fillings and implants, scientists say' – UK research team @KingsCollegeLon moves closer to growing natural tooth replacements using stem cells and bioengineered environments [Paper: https://t.co/2Jgf62ZNGd]: https://t.co/oNyDcZimYy

Apr 28, 2025 · 1 like · 14,876 followers View post →

All mentions

chibaf
@chibafx · X

Generating Tooth Organoids Using Defined Bioorthogonally Cross-Linked Hydrogels - PubMed https://t.co/t8whEqUbP5 Lab-grown teeth might become an alternative to fillings following research breakthrough | King's College London https://t.co/TYGoOIArI1

May 11, 2025 · 635 followers View post →
Gabriel Serrano
@gserranoeng · X

¡Los científicos han crecido dientes vivos en el laboratorio! Los científicos del King's College de Londres han hecho un gran avance en la odontología regenerativa creciendo dientes vivos en el laboratorio. ➡️ https://t.co/25vci9EswU https://t.co/OiTZEseqx2

May 5, 2025 View post →
Dr. Shahid Aziz
@Shahid_cl · X

Lab-grown teeth would naturally regenerate, integrating into the jaw as real teeth. Stronger, longer-lasting, and free from rejection risks, offering a more durable and biologically compatible solution than filling or implants. @KingsCollegeLon DOI: 10.1021/acsmacrolett.4c00520 https://t.co/VHyHzG6d97

May 3, 2025 · 2 likes · 939 followers View post →
polvo
@coprodu.to · Bluesky

Mas há outras possibilidades interessantes com transplantes autólogos. Uma que li recentemente um artigo sobre e achei bem legal seria de clonar *dentes* pra pessoas que tenham perdido em acidentes, por exemplo. pubmed.ncbi.nlm.nih.gov/39532305/

Apr 30, 2025 · 3 likes · 1 share View post →
el hombre pulpo
@coproduto · X

Mas há outras possibilidades interessantes com transplantes autólogos. Uma que li recentemente um artigo sobre e achei bem legal seria de clonar *dentes* pra pessoas que tenham perdido em acidentes, por exemplo. https://t.co/PahS0urgit

Apr 30, 2025 · 1 like · 22,129 followers View post →
Stem Cell Foundation
@AusStemCell · X

‘Lab-grown teeth could offer alternative to fillings and implants, scientists say' – UK research team @KingsCollegeLon moves closer to growing natural tooth replacements using stem cells and bioengineered environments [Paper: https://t.co/2Jgf62ZNGd]: https://t.co/oNyDcZimYy

Apr 28, 2025 · 1 like · 14,876 followers View post →
Candi (No
@acabchick.bsky.social · Bluesky

#Lab #Grown #Teeth #Breakthrough #Research Detailed research info. at below #NIH #NLM link. pubmed.ncbi.nlm.nih.gov/39532305/

Apr 24, 2025 · 8 likes · 2 shares View post →
Professor Erwin Loh
@erwinloh · X

Lab-grown teeth might become an alternative to fillings following research breakthrough Adults could one day grow their own replacement teeth instead of having fillings – as scientists make a key discovery. https://t.co/UYJlOCY3eJ https://t.co/MpgdRD6t3m

Apr 19, 2025 · 9,489 followers View post →
rajesh
@rajesh_0077 · X

Check out this research output at King's College London: Generating Tooth Organoids Using Defined Bioorthogonally Cross-Linked Hydrogels https://t.co/wf4xnMNRPs

Apr 15, 2025 · 21 followers View post →
Imperial Bioengineering
@ImperialBioeng · X

RT @celizlab: Check out our latest paper in @ACSMacroLett on defined hydrogels for tooth organoid formation. Great collaboration with @king…

Nov 15, 2024 · 5 shares · 7,257 followers View post →
Dentistry, Oral & Craniofacial Sciences at King's
@kingsdentistry · X

RT @celizlab: Check out our latest paper in @ACSMacroLett on defined hydrogels for tooth organoid formation. Great collaboration with @king…

Nov 15, 2024 · 5 shares · 5,372 followers View post →
Xuechen
@Xuechennnnn · X

RT @celizlab: Check out our latest paper in @ACSMacroLett on defined hydrogels for tooth organoid formation. Great collaboration with @king…

Nov 15, 2024 · 5 shares · 15 followers View post →
Alex Correia
@alexcor · X

RT @celizlab: Check out our latest paper in @ACSMacroLett on defined hydrogels for tooth organoid formation. Great collaboration with @king…

Nov 14, 2024 · 5 shares · 505 followers View post →
Nicola C Negrini
@ContessiNicola · X

RT @celizlab: Check out our latest paper in @ACSMacroLett on defined hydrogels for tooth organoid formation. Great collaboration with @king…

Nov 14, 2024 · 5 shares · 158 followers View post →
Celiz Lab
@celizlab · X

Check out our latest paper in @ACSMacroLett on defined hydrogels for tooth organoid formation. Great collaboration with @kingsdentistry. @ContessiNicola @ImperialBioeng https://t.co/vOF9zWWVcO

Nov 14, 2024 · 19 likes · 5 shares · 779 followers View post →