This collection of discussions strongly supports the research's promising findings, with enthusiastic remarks such as 'transformative research' and 'potential therapeutic avenue,' suggesting widespread excitement about the implications. People reference the substantial increases in regeneration in LVAD patients, the possible shift in treatment paradigms, and the collaborative nature of the work, showing both deep engagement and recognition of high-impact potential.
AgreementStrong agreement
Most discussions express strong support, emphasizing the potential of heart regeneration therapies, with phrases like 'promising new avenues' and 'transformative research'.
InterestHigh interest
The posts highlight high engagement with terms like 'excited', 'thrilled', and references to new findings, indicating strong interest.
EngagementModerate engagement
Participants reference specific mechanisms and future implications, showing thoughtful engagement, although some comments are more about sharing rather than deep analysis.
ImpactHigh impact
Multiple comments underscore the possible revolutionary impact on heart failure treatment and the significant boost in cardiomyocyte regeneration, emphasizing high perceived impact.
Abstract in brief
Cardiomyocytes in adult human hearts have a low regeneration rate of about 0.5% per year, raising questions about their role in heart failure recovery.
Patients with advanced heart failure showed dramatically reduced cardiomyocyte renewal, with rates significantly lower than healthy individuals, while those with left ventricular assist devices (LVAD) experienced a notable increase in regeneration.
These results suggest that the heart retains a potential for regeneration in disease states, which could be harnessed for future therapies.
Excited to share the latest collaboration spearheaded by @oibergmann @FrisenJonas @StavrosDrakos this work started with our Leducq consortium 6 years ago showing that LVAD responders have a higher rate of new myocytes formation. https://t.co/pjNcPtRyzy
Nov 21, 2024 · 49 likes · 9 shares · 1,634 followersView post →
Nov 25, 2024 · 30 likes · 24 shares · 77,755 followersView post →
OB
Olaf Bergmann
@oibergmann · X
Mechanical unloading unlocks latent regenerative potential. Cardiomyocyte renewal is boosted in LVAD responders. Great Leducq collaboration! @FrisenJonas @StavrosDrakos @heshamasadek
https://t.co/z64hz23e3l
https://t.co/sHetWE2dl5
Nov 21, 2024 · 16 likes · 6 shares · 49 followersView post →
JT
Joseph Taleb
@Joseph_Taleb · X
Thrilled to share our study in Circulation! https://t.co/hmUIrjgnGG
Led by @oibergmann, we found a >6-fold boost in cardiac regeneration in LVAD responders vs healthy hearts. Honored to be part of this transformative research. @UofUCV @UCSDCardiology
Nov 21, 2024 · 10 likes · 3 shares · 277 followersView post →
FR
Fabian Rost
@fabianrost84 · X
Turning nuclear fallout into heart-healing insights.
Nov 22, 2024 · 4 likes · 1 share · 157 followersView post →
AM
Ahmed Bennis MD
@drbennisahmed · X
A Latent Cardiomyocyte Regeneration Potential in Human Heart Disease
Our findings reveal a substantial cardiomyocyte regeneration potential in human heart disease, which could be exploited therapeutically.
https://t.co/bSRAkZ7GhS https://t.co/tGW72ZMCor
Nov 26, 2024 · 2 likes · 3,259 followersView post →
Cardiomyocytes in adult human hearts have a low regeneration rate of about 0.5% per year, raising questions about their role in heart failure recovery. Patients with advanced heart failure showed dramatically reduced…
Researchers discovered that patients with artificial hearts can regenerate cardiac muscle tissue at six times the rate of healthy hearts, suggesting potential treatments for heart failure. This regeneration is linked to…
A new study shows that #heart muscle #regeneration occurred in approximately 25% of #LVAD patients. These results open promising new avenues for treating heart failure, which causes 14% of annual deaths in the US.
https://t.co/Qj3TBbOdVc https://t.co/gxDCTRWtY5
Cardiomyocyte regeneration in heart failure is minimal, but significantly boosts with left ventricular assist device therapy, showcasing therapeutic potential.
by Derks W, Rode J (...) Bergmann O et 23 al. in Circulation
https://t.co/oO6Z3F1nkA #MedX #MedResearch
RT @CircAHA: Patients with LVAD demonstrate substantial cardiomyocyte regeneration, highlighting a potential therapeutic avenue @frisenjona…
Jan 24, 2025 · 24 shares · 114 followersView post →
AA
Alberto Aimo
@AlbertoAimo90 · X
RT @CircAHA: Patients with LVAD demonstrate substantial cardiomyocyte regeneration, highlighting a potential therapeutic avenue @frisenjona…
Jan 24, 2025 · 24 shares · 2,084 followersView post →
ME
McMaster Heart Function Education
@MacHeartFailure · X
RT @CircAHA: Patients with LVAD demonstrate substantial cardiomyocyte regeneration, highlighting a potential therapeutic avenue @frisenjona…
Jan 24, 2025 · 24 shares · 514 followersView post →
MT
Misako TOKI
@misako_desu · X
RT @CircAHA: Patients with LVAD demonstrate substantial cardiomyocyte regeneration, highlighting a potential therapeutic avenue @frisenjona…
Jan 24, 2025 · 24 shares · 957 followersView post →
S智
Satoshi Miyashita, MD | 宮下 智
@satoshiboston · X
RT @CircAHA: Patients with LVAD demonstrate substantial cardiomyocyte regeneration, highlighting a potential therapeutic avenue @frisenjona…
Jan 23, 2025 · 24 shares · 1,994 followersView post →
RM
Ryan Williams, MD
@RyanJWilliamsMD · X
RT @CircAHA: Patients with LVAD demonstrate substantial cardiomyocyte regeneration, highlighting a potential therapeutic avenue @frisenjona…
Dec 22, 2024 · 24 shares · 112 followersView post →
UC
UArizona Sarver Heart Center
@UAZHeart · X
New research co-authored by Sarver Heart Center Director, Hesham Sadek, MD, PhD, reveals that 25% of artificial heart patients regenerate heart muscle after a heart attack. These findings could transform heart failure treatment. Learn more: https://t.co/R3myX9N9un #HeartResearch
Dec 20, 2024 · 2 likes · 1 share · 1,626 followersView post →
IU
Institute of Pharmacology and Toxicology, UMG
@pharmaumg · X
RT @oibergmann: Mechanical unloading unlocks latent regenerative potential. Cardiomyocyte renewal is boosted in LVAD responders. Great Ledu…
Dec 20, 2024 · 6 shares · 270 followersView post →
RT @CircAHA: Patients with LVAD demonstrate substantial cardiomyocyte regeneration, highlighting a potential therapeutic avenue @frisenjona…
Dec 1, 2024 · 24 shares · 449 followersView post →
TS
Thirupura Shankar
@ThirupuraShank1 · X
RT @CircAHA: Patients with LVAD demonstrate substantial cardiomyocyte regeneration, highlighting a potential therapeutic avenue @frisenjona…
Nov 29, 2024 · 24 shares · 79 followersView post →
EF
Endo Fellow
@endo_fellow · X
RT @CircAHA: Patients with LVAD demonstrate substantial cardiomyocyte regeneration, highlighting a potential therapeutic avenue @frisenjona…
Nov 29, 2024 · 24 shares · 32 followersView post →
FD
Francesco Dellagrazia
@_radikalek · X
RT @CircAHA: Patients with LVAD demonstrate substantial cardiomyocyte regeneration, highlighting a potential therapeutic avenue @frisenjona…
Nov 26, 2024 · 24 shares · 1,607 followersView post →
JH
Joseph hill
@josephahill · X
RT @CircAHA: Patients with LVAD demonstrate substantial cardiomyocyte regeneration, highlighting a potential therapeutic avenue @frisenjona…
Nov 26, 2024 · 24 shares · 2,447 followersView post →
は心
はっか@ICU×循内×心エコー×心リハ
@Super_hakka31 · X
RT @CircAHA: Patients with LVAD demonstrate substantial cardiomyocyte regeneration, highlighting a potential therapeutic avenue @frisenjona…
Nov 26, 2024 · 24 shares · 595 followersView post →
FR
Felix Rausch
@felix_mller · X
RT @CircAHA: Patients with LVAD demonstrate substantial cardiomyocyte regeneration, highlighting a potential therapeutic avenue @frisenjona…
Nov 26, 2024 · 24 shares · 149 followersView post →
AM
Ahmed Bennis MD
@drbennisahmed · X
A Latent Cardiomyocyte Regeneration Potential in Human Heart Disease
Our findings reveal a substantial cardiomyocyte regeneration potential in human heart disease, which could be exploited therapeutically.
https://t.co/bSRAkZ7GhS https://t.co/tGW72ZMCor
Nov 26, 2024 · 2 likes · 3,259 followersView post →
IN
Ivan Netuka
@netuka_ivan · X
RT @CircAHA: Patients with LVAD demonstrate substantial cardiomyocyte regeneration, highlighting a potential therapeutic avenue @frisenjona…
Nov 26, 2024 · 24 shares · 323 followersView post →
JA
Junedh M. Amrute
@junedh_amrute · X
RT @CircAHA: Patients with LVAD demonstrate substantial cardiomyocyte regeneration, highlighting a potential therapeutic avenue @frisenjona…
Nov 25, 2024 · 24 shares · 475 followersView post →
SG
Shinya Goto
@sgoto4 · X
RT @CircAHA: Patients with LVAD demonstrate substantial cardiomyocyte regeneration, highlighting a potential therapeutic avenue @frisenjona…
Nov 25, 2024 · 24 shares · 322 followersView post →
C日
Circulation 日本版
@Circulation_nih · X
RT @CircAHA: Patients with LVAD demonstrate substantial cardiomyocyte regeneration, highlighting a potential therapeutic avenue @frisenjona…
Nov 25, 2024 · 24 shares · 352 followersView post →
CK
Christos P. Kyriakopoulos
@CPKyriakopoulos · X
RT @CircAHA: Patients with LVAD demonstrate substantial cardiomyocyte regeneration, highlighting a potential therapeutic avenue @frisenjona…
Nov 25, 2024 · 24 shares · 395 followersView post →
JT
Joseph Taleb
@Joseph_Taleb · X
RT @CircAHA: Patients with LVAD demonstrate substantial cardiomyocyte regeneration, highlighting a potential therapeutic avenue @frisenjona…
Nov 25, 2024 · 24 shares · 277 followersView post →
MM
Manoj Mayogi Mishra
@mayogisense · X
RT @CircAHA: Patients with LVAD demonstrate substantial cardiomyocyte regeneration, highlighting a potential therapeutic avenue @frisenjona…
Nov 25, 2024 · 24 shares · 573 followersView post →
BW
Bowen Wang
@NU_JEANSS · X
RT @CircAHA: Patients with LVAD demonstrate substantial cardiomyocyte regeneration, highlighting a potential therapeutic avenue @frisenjona…
Nov 25, 2024 · 24 shares · 274 followersView post →
SF
Sherry-Ann Brown, MD, PhD, FACC, FAHA
@drbrowncares · X
RT @CircAHA: Patients with LVAD demonstrate substantial cardiomyocyte regeneration, highlighting a potential therapeutic avenue @frisenjona…
Nov 25, 2024 · 24 shares · 7,755 followersView post →
CF
Christin Franke
@ChristinFranke2 · X
RT @CircAHA: Patients with LVAD demonstrate substantial cardiomyocyte regeneration, highlighting a potential therapeutic avenue @frisenjona…
Nov 25, 2024 · 24 shares · 102 followersView post →
TK
Tim Kambič
@TimKambic · X
RT @CircAHA: Patients with LVAD demonstrate substantial cardiomyocyte regeneration, highlighting a potential therapeutic avenue @frisenjona…
Nov 25, 2024 · 24 shares · 234 followersView post →
RT @Joseph_Taleb: Thrilled to share our study in Circulation! https://t.co/hmUIrjgnGG
Led by @oibergmann, we found a >6-fold boost in cardi…
Nov 22, 2024 · 3 shares · 808 followersView post →
TL
The Dobreva Lab
@DobrevaLab · X
RT @heshamasadek: Excited to share the latest collaboration spearheaded by @oibergmann @FrisenJonas @StavrosDrakos this work started with o…
Nov 22, 2024 · 9 shares · 388 followersView post →
PL
Professor Erwin Loh
@erwinloh · X
Researchers found that a damaged #heart's ability to #generate new #muscle cells is up to six times greater than that of a healthy heart. But the mechanism behind the effect is still unknown and there isn’t yet any hypothesis to explain it.
https://t.co/Q6gsBL5fKZ https://t.co/Ly9gxFQph9
RT @Joseph_Taleb: Thrilled to share our study in Circulation! https://t.co/hmUIrjgnGG
Led by @oibergmann, we found a >6-fold boost in cardi…
Nov 22, 2024 · 3 shares · 814 followersView post →
CD
Carles Díez
@diez_carles · X
RT @heshamasadek: Excited to share the latest collaboration spearheaded by @oibergmann @FrisenJonas @StavrosDrakos this work started with o…
Nov 22, 2024 · 9 shares · 763 followersView post →
CK
Christos P. Kyriakopoulos
@CPKyriakopoulos · X
RT @oibergmann: Mechanical unloading unlocks latent regenerative potential. Cardiomyocyte renewal is boosted in LVAD responders. Great Ledu…
Nov 22, 2024 · 6 shares · 395 followersView post →
CK
Christos P. Kyriakopoulos
@CPKyriakopoulos · X
RT @heshamasadek: Excited to share the latest collaboration spearheaded by @oibergmann @FrisenJonas @StavrosDrakos this work started with o…
Nov 22, 2024 · 9 shares · 395 followersView post →
JT
Joseph Taleb
@Joseph_Taleb · X
Thrilled to share our study in Circulation! https://t.co/hmUIrjgnGG
Led by @oibergmann, we found a >6-fold boost in cardiac regeneration in LVAD responders vs healthy hearts. Honored to be part of this transformative research. @UofUCV @UCSDCardiology
Nov 21, 2024 · 10 likes · 3 shares · 277 followersView post →
SD
Stavros George Drakos
@StavrosDrakos · X
RT @oibergmann: Mechanical unloading unlocks latent regenerative potential. Cardiomyocyte renewal is boosted in LVAD responders. Great Ledu…
Nov 21, 2024 · 6 shares · 4,056 followersView post →
VP
Vikram Prasad
@prasad_vik · X
RT @heshamasadek: Excited to share the latest collaboration spearheaded by @oibergmann @FrisenJonas @StavrosDrakos this work started with o…
Nov 21, 2024 · 9 shares · 144 followersView post →
HS
Hesham Sadek
@heshamasadek · X
RT @oibergmann: Mechanical unloading unlocks latent regenerative potential. Cardiomyocyte renewal is boosted in LVAD responders. Great Ledu…
Nov 21, 2024 · 6 shares · 1,634 followersView post →
OB
Olaf Bergmann
@oibergmann · X
Mechanical unloading unlocks latent regenerative potential. Cardiomyocyte renewal is boosted in LVAD responders. Great Leducq collaboration! @FrisenJonas @StavrosDrakos @heshamasadek
https://t.co/z64hz23e3l
https://t.co/sHetWE2dl5
Nov 21, 2024 · 16 likes · 6 shares · 49 followersView post →
HS
Hesham Sadek
@heshamasadek · X
Excited to share the latest collaboration spearheaded by @oibergmann @FrisenJonas @StavrosDrakos this work started with our Leducq consortium 6 years ago showing that LVAD responders have a higher rate of new myocytes formation. https://t.co/pjNcPtRyzy
Nov 21, 2024 · 49 likes · 9 shares · 1,634 followersView post →
UI
UofU3i
@UofU3i · X
New 3i Investigator Article Alert!! A latent cardiomyocyte regeneration potential in human heart disease https://t.co/LluZ5snNUd
Can the heart heal itself? New study says it can. University of Arizona Health Sciences. Journal: Circulation; DOI: 10.1161/CIRCULATIONAHA.123.067156 ...