Transfusion Practices in Traumatic Brain Injury: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Anna Laura Lima Larcipretti, Ofonime Chantal Udoma-Udofa, Fernando Cotrim Gomes, Jéssica Sales de Oliveira, Elizabet Taylor Pimenta Weba, Deivyd Vieira Silva Cavalcante, Madhav Kiritbhai Dharaiya, Matheus de Andrade Bannach

April 2025

Synopsis of Social media discussions

Discussions highlight the key finding that a transfusion threshold of 9 g/dL likely improves neurological recovery, with posts describing this as a 'game changer' for TBI treatment. The tone is analytical yet optimistic, emphasizing the article’s potential to change clinical protocols and improve patient outcomes.

A
Agreement
 Moderate agreement

Most discussions support the idea that a more liberal transfusion strategy improves neurologic outcomes in TBI patients, reflecting consensus on the article's findings.

I
Interest
 High level of interest

The majority of posts show high interest, emphasizing the potential clinical benefits and adoption of the insights from the review.

E
Engagement
 Moderate level of engagement

Posts reference specific details such as hemoglobin thresholds and results from randomized trials, indicating moderate engagement.

I
Impact
 Moderate level of impact

The discussions suggest the publication could influence clinical practices and guidelines, implying a moderate to high impact.

Social Mentions

YouTube

2 Videos

Twitter

11 Posts

Metrics

Video Views

429

Total Likes

41

Extended Reach

178,827

Social Features

13

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

Transfusion Strategies in Traumatic Brain Injury Clinical Review

Transfusion Strategies in Traumatic Brain Injury Clinical Review

This video reviews a systematic analysis comparing liberal and restrictive blood transfusion strategies in TBI patients, finding potential benefits of liberal thresholds for neurologic recovery and implications for clinical guidelines.

SCCM

April 7, 2025

419 views

Blood Transfusion Strategies in Traumatic Brain Injury Clinical Outcomes

Blood Transfusion Strategies in Traumatic Brain Injury Clinical Outcomes

This episode discusses a systematic review comparing liberal and restrictive transfusion strategies in TBI patients. The study found that liberal transfusions improve neurologic outcomes, emphasizing the importance of optimizing transfusion thresholds to enhance recovery.

SCCM

October 3, 2025

11 views

  • Almansour
    @malmansour81 (Twitter)

    RT @SCCM_Neuro: This SRMA found that liberal transfusion strategy (Hgb 9-10) resulted in better neurologic outcomes in TBI patients than a…
    view full post

    July 1, 2025

    4

  • Gustavo Domeniconi
    @gdomeni (Twitter)

    RT @SCCM_Neuro: This SRMA found that liberal transfusion strategy (Hgb 9-10) resulted in better neurologic outcomes in TBI patients than a…
    view full post

    June 30, 2025

    4

  • Sulaiman Almohaish
    @DrSulaiman89 (Twitter)

    RT @SCCM_Neuro: This SRMA found that liberal transfusion strategy (Hgb 9-10) resulted in better neurologic outcomes in TBI patients than a…
    view full post

    June 30, 2025

    4

  • Mauricio Cantillano
    @CantillMauricio (Twitter)

    RT @SCCM_Neuro: This SRMA found that liberal transfusion strategy (Hgb 9-10) resulted in better neurologic outcomes in TBI patients than a…
    view full post

    June 30, 2025

    4

  • SCCM Neuroscience Section
    @SCCM_Neuro (Twitter)

    This SRMA found that liberal transfusion strategy (Hgb 9-10) resulted in better neurologic outcomes in TBI patients than a restrictive (Hgb 7) approach. A transfusion threshold of 9g/dL in TBI may be ideal.
    view full post

    June 30, 2025

    7

    4

  • Nicholas Morris
    @namorrismd (Twitter)

    Transfusion Practices in Traumatic Brain Injury: A Systematic Review and Meta-Analysis of Randomized Controlled Trials : @CritCareMed https://t.co/SugCWBsNsu https://t.co/E0TituuvIT
    view full post

    February 13, 2025

    2

  • Gustavo Flores
    @gflores911 (Twitter)

    Transfusion Practices in Traumatic Brain Injury: A Systematic Review and Meta-Analysis of Randomized Controlled Trials https://t.co/4yUOJSurSy
    view full post

    February 11, 2025

  • ケースケ@LessIsMoreICU
    @lessismoreicu (Twitter)

    RT @lessismoreicu: TBIでの輸血閾値は制限的よりも非制限の輸血戦略の方が神経学的転帰が良好であることを示唆され、標準的な閾値として9g/dLを提唱する、というRCTのSR&ＭＡ。 ただ非制限はARDS有病率の有意な増加と輸血単位数の増加と関連していたと。…
    view full post

    January 31, 2025

    3

  • JACK
    @gunpla08 (Twitter)

    RT @lessismoreicu: TBIでの輸血閾値は制限的よりも非制限の輸血戦略の方が神経学的転帰が良好であることを示唆され、標準的な閾値として9g/dLを提唱する、というRCTのSR&ＭＡ。 ただ非制限はARDS有病率の有意な増加と輸血単位数の増加と関連していたと。…
    view full post

    January 31, 2025

    3

  • ケースケ@LessIsMoreICU
    @lessismoreicu (Twitter)

    TBIでの輸血閾値は制限的よりも非制限の輸血戦略の方が神経学的転帰が良好であることを示唆され、標準的な閾値として9g/dLを提唱する、というRCTのSR&ＭＡ。 ただ非制限はARDS有病率の有意な増加と輸血単位数の増加と関連していたと。 https://t.co/8bNfcQm3GG
    view full post

    January 31, 2025

    21

    3

  • EARLの医学&AIノート
    @EARL_med_tw (Twitter)


    view full post

    January 30, 2025

    7

Abstract Synopsis

  • This systematic review and meta-analysis examined whether liberal or restrictive blood transfusion strategies are better for patients with traumatic brain injury (TBI), analyzing data from five randomized controlled trials involving 1,533 patients.
  • The results showed no significant difference between the two strategies in terms of mortality, infection rates, or hospital stay, but the liberal approach was associated with improved neurologic outcomes and a higher risk of certain complications like acute respiratory distress syndrome.
  • The authors suggest that using a more liberal transfusion threshold (e.g., 9 g/dL hemoglobin level) might enhance neurologic recovery in TBI patients and recommend updating clinical guidelines accordingly.