PubHawk
April 2025 PMID 39878558

Transfusion Practices in Traumatic Brain Injury: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Anna Laura Lima Larcipretti, Ofonime Chantal Udoma-Udofa, Fernando Cotrim Gomes, Jéssica Sales de Oliveira, Elizabet Taylor Pimenta Weba, Deivyd Vieira Silva Cavalcante, Madhav Kiritbhai Dharaiya, Matheus de Andrade Bannach

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Mentions

13
Peak: 4 in Jan 2025
across 2 sources since Jan 2025

Extended reach

178,827
potential audience

Total likes

41

Video views

429

Mentions per month

Jan 2025 – Oct 2025

Where it's discussed

  • X / Twitter11 posts
  • YouTube2 videos

AI synopsis

What people are saying

Discussions highlight the key finding that a transfusion threshold of 9 g/dL likely improves neurological recovery, with posts describing this as a 'game changer' for TBI treatment. The tone is analytical yet optimistic, emphasizing the article’s potential to change clinical protocols and improve patient outcomes.

AgreementModerate agreement

Most discussions support the idea that a more liberal transfusion strategy improves neurologic outcomes in TBI patients, reflecting consensus on the article's findings.

InterestHigh interest

The majority of posts show high interest, emphasizing the potential clinical benefits and adoption of the insights from the review.

EngagementModerate engagement

Posts reference specific details such as hemoglobin thresholds and results from randomized trials, indicating moderate engagement.

ImpactModerate impact

The discussions suggest the publication could influence clinical practices and guidelines, implying a moderate to high impact.

Abstract in brief

  • This systematic review and meta-analysis examined whether liberal or restrictive blood transfusion strategies are better for patients with traumatic brain injury (TBI), analyzing data from five randomized controlled trials involving 1,533 patients.
  • The results showed no significant difference between the two strategies in terms of mortality, infection rates, or hospital stay, but the liberal approach was associated with improved neurologic outcomes and a higher risk of certain complications like acute respiratory distress syndrome.
  • The authors suggest that using a more liberal transfusion threshold (e.g., 9 g/dL hemoglobin level) might enhance neurologic recovery in TBI patients and recommend updating clinical guidelines accordingly.
Read the full abstract

Top posts

Most liked on X and Bluesky
ケースケ@LessIsMoreICU
@lessismoreicu · X

TBIでの輸血閾値は制限的よりも非制限の輸血戦略の方が神経学的転帰が良好であることを示唆され、標準的な閾値として9g/dLを提唱する、というRCTのSR&ＭＡ。 ただ非制限はARDS有病率の有意な増加と輸血単位数の増加と関連していたと。 https://t.co/8bNfcQm3GG

Jan 31, 2025 · 21 likes · 3 shares · 6,003 followers View post →
EARLの医学&AIノート
@EARL_med_tw · X

Jan 30, 2025 · 7 likes · 148,083 followers View post →
SCCM Neuroscience Section
@SCCM_Neuro · X

This SRMA found that liberal transfusion strategy (Hgb 9-10) resulted in better neurologic outcomes in TBI patients than a restrictive (Hgb 7) approach. A transfusion threshold of 9g/dL in TBI may be ideal.

Jun 30, 2025 · 7 likes · 4 shares · 1,215 followers View post →
Nicholas Morris
@namorrismd · X

Transfusion Practices in Traumatic Brain Injury: A Systematic Review and Meta-Analysis of Randomized Controlled Trials : @CritCareMed https://t.co/SugCWBsNsu https://t.co/E0TituuvIT

Feb 13, 2025 · 2 likes · 1,930 followers View post →
ケースケ@LessIsMoreICU
@lessismoreicu · X

RT @lessismoreicu: TBIでの輸血閾値は制限的よりも非制限の輸血戦略の方が神経学的転帰が良好であることを示唆され、標準的な閾値として9g/dLを提唱する、というRCTのSR&ＭＡ。 ただ非制限はARDS有病率の有意な増加と輸血単位数の増加と関連していたと。…

Jan 31, 2025 · 3 shares · 6,003 followers View post →
JACK
@gunpla08 · X

RT @lessismoreicu: TBIでの輸血閾値は制限的よりも非制限の輸血戦略の方が神経学的転帰が良好であることを示唆され、標準的な閾値として9g/dLを提唱する、というRCTのSR&ＭＡ。 ただ非制限はARDS有病率の有意な増加と輸血単位数の増加と関連していたと。…

Jan 31, 2025 · 3 shares · 5,982 followers View post →

All mentions

Almansour
@malmansour81 · X

RT @SCCM_Neuro: This SRMA found that liberal transfusion strategy (Hgb 9-10) resulted in better neurologic outcomes in TBI patients than a…

Jul 1, 2025 · 4 shares · 214 followers View post →
Gustavo Domeniconi
@gdomeni · X

RT @SCCM_Neuro: This SRMA found that liberal transfusion strategy (Hgb 9-10) resulted in better neurologic outcomes in TBI patients than a…

Jun 30, 2025 · 4 shares · 910 followers View post →
Sulaiman Almohaish
@DrSulaiman89 · X

RT @SCCM_Neuro: This SRMA found that liberal transfusion strategy (Hgb 9-10) resulted in better neurologic outcomes in TBI patients than a…

Jun 30, 2025 · 4 shares · 498 followers View post →
Mauricio Cantillano
@CantillMauricio · X

RT @SCCM_Neuro: This SRMA found that liberal transfusion strategy (Hgb 9-10) resulted in better neurologic outcomes in TBI patients than a…

Jun 30, 2025 · 4 shares · 3,588 followers View post →
SCCM Neuroscience Section
@SCCM_Neuro · X

This SRMA found that liberal transfusion strategy (Hgb 9-10) resulted in better neurologic outcomes in TBI patients than a restrictive (Hgb 7) approach. A transfusion threshold of 9g/dL in TBI may be ideal.

Jun 30, 2025 · 7 likes · 4 shares · 1,215 followers View post →
Nicholas Morris
@namorrismd · X

Transfusion Practices in Traumatic Brain Injury: A Systematic Review and Meta-Analysis of Randomized Controlled Trials : @CritCareMed https://t.co/SugCWBsNsu https://t.co/E0TituuvIT

Feb 13, 2025 · 2 likes · 1,930 followers View post →
Gustavo Flores
@gflores911 · X

Transfusion Practices in Traumatic Brain Injury: A Systematic Review and Meta-Analysis of Randomized Controlled Trials https://t.co/4yUOJSurSy

Feb 11, 2025 · 3,915 followers View post →
ケースケ@LessIsMoreICU
@lessismoreicu · X

RT @lessismoreicu: TBIでの輸血閾値は制限的よりも非制限の輸血戦略の方が神経学的転帰が良好であることを示唆され、標準的な閾値として9g/dLを提唱する、というRCTのSR&ＭＡ。 ただ非制限はARDS有病率の有意な増加と輸血単位数の増加と関連していたと。…

Jan 31, 2025 · 3 shares · 6,003 followers View post →
JACK
@gunpla08 · X

RT @lessismoreicu: TBIでの輸血閾値は制限的よりも非制限の輸血戦略の方が神経学的転帰が良好であることを示唆され、標準的な閾値として9g/dLを提唱する、というRCTのSR&ＭＡ。 ただ非制限はARDS有病率の有意な増加と輸血単位数の増加と関連していたと。…

Jan 31, 2025 · 3 shares · 5,982 followers View post →
ケースケ@LessIsMoreICU
@lessismoreicu · X

TBIでの輸血閾値は制限的よりも非制限の輸血戦略の方が神経学的転帰が良好であることを示唆され、標準的な閾値として9g/dLを提唱する、というRCTのSR&ＭＡ。 ただ非制限はARDS有病率の有意な増加と輸血単位数の増加と関連していたと。 https://t.co/8bNfcQm3GG

Jan 31, 2025 · 21 likes · 3 shares · 6,003 followers View post →
EARLの医学&AIノート
@EARL_med_tw · X

Jan 30, 2025 · 7 likes · 148,083 followers View post →