Chest August 2025 PMID 39971001

Normosol-R vs Lactated Ringers in the Critically Ill: A Randomized Trial.

Edward T Qian, Ryan M Brown, Karen E Jackson, Li Wang, Joanna L Stollings, Robert E Freundlich, Jonathan P Wanderer, Edward D Siew, Gordon R Bernard, Wesley H Self, Jonathan D Casey, Todd W Rice, Matthew W Semler

Mentions

3
Peak: 3 in Feb 2025
across 2 sources since Feb 2025

Extended reach

1,106
potential audience

Total likes

37

Video views

1,101

Mentions per month

Feb 2025

All 3 dated mentions so far are from Feb 2025.

Where it's discussed

  • YouTube2 videos
  • Bluesky1 posts

AI synopsis

What people are saying

The discussions reflect a nuanced understanding of fluid therapy history, with reflections like 'Pendant 15 ans, nous avons eu droit aux débats...' indicating a focus on longstanding debates. Words like 'compare,' 'débats,' and references to pubmed articles demonstrate an analytical tone that recognizes the study's contribution but also historical context, suggesting moderate interest and impact.

AgreementModerate agreement

Some posts acknowledge the study's findings, highlighting the lack of significant differences between Normosol-R and lactated Ringers, indicating moderate agreement with the results.

InterestModerate interest

Discussions show a moderate level of curiosity, especially with references to the ongoing debates about fluid choices and historical comparisons.

EngagementNeutral engagement

Posts mainly reference historical debates and the implications for clinical practice without deeply analyzing the study methodology, showing limited engagement.

ImpactNeutral impact

The conversations suggest the study's findings may influence clinical choices but don't currently seem to shift practice patterns significantly.

Abstract in brief

  • The study compared NormosolR and lactated Ringers in critically ill adults and found no significant difference in plasma bicarbonate levels, kidney therapy needs, or mortality rates between the two fluids.
  • The primary measure, plasma bicarbonate concentration over 7 days, showed no significant variation, indicating similar effects on acid-base balance for both solutions.
  • Overall, using NormosolR did not improve clinical outcomes or organ function compared to lactated Ringers in this patient population.

Top posts

Most liked on X and Bluesky
Damien BARRAUD MD
@damienbarraudmd.bsky.social · Bluesky

Fluids history : Pendant 15 ans, nous avons eu droit aux débats CRISTALLOÎDES vs COLLOIDES... Depuis 10 ans, nous avons eu droit aux débats SERUM "PHYSIOLOGIQUE" vs CRISTALLOÏDES "EQUILIBRES"... Voici venir les comparaisons entre CRISTALLOÏDES EQUILIBRES... pubmed.ncbi.nlm.nih.gov/39971001/

Feb 24, 2025 · 6 likes · 3 shares View post →

All mentions

Damien BARRAUD MD
@damienbarraudmd.bsky.social · Bluesky

Fluids history : Pendant 15 ans, nous avons eu droit aux débats CRISTALLOÎDES vs COLLOIDES... Depuis 10 ans, nous avons eu droit aux débats SERUM "PHYSIOLOGIQUE" vs CRISTALLOÏDES "EQUILIBRES"... Voici venir les comparaisons entre CRISTALLOÏDES EQUILIBRES... pubmed.ncbi.nlm.nih.gov/39971001/

Feb 24, 2025 · 6 likes · 3 shares View post →