N Engl J Med April 2025 PMID 40174223

Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours.

Shenqiang Yan, Ying Zhou, Maarten G Lansberg, David S Liebeskind, Changzheng Yuan, Han Yu, Fujian Chen, Hongfang Chen, Bing Zhang, Lingqun Mao, Xiaoling Zhang, Xiaona Wang, Xuting Zhang, Yi Chen, Huan Zhou

Mentions

190
Peak: 110 in Apr 2025
across 6 sources since Apr 2025

Extended reach

3,124,972
potential audience

Total likes

754

Video views

785

Mentions per month

Apr 2025 – Aug 2025

Where it's discussed

  • X / Twitter167 posts
  • News11 articles
  • Bluesky4 posts
  • Facebook3 posts
  • Blogs3 articles
  • YouTube2 videos

AI synopsis

What people are saying

Numerous posts reference the core findings from the EXPECTS trial, specifically mentioning that patients receiving alteplase within the specified time frame had improved functional independence (89.6% vs. 72.6%). The language used, such as terms like 'significant' and 'promise,' adds to the urgency and enthusiasm around the findings, indicating to readers that this research could reshape treatment paradigms.

AgreementModerate agreement

Many posts show a balanced viewpoint, acknowledging the potential benefits of alteplase while highlighting safety concerns.

InterestHigh interest

The discussions exhibit high engagement with the topic, reflecting a strong desire for information about alteplase's effects.

EngagementModerate engagement

Some contributors delve into specific study outcomes, such as the metrics for functional independence and safety profiles.

ImpactHigh impact

Overall, there is a consensus that the findings may significantly affect clinical practices in treating posterior circulation ischemic stroke.

Abstract in brief

  • The study examines the effects of intravenous thrombolysis with alteplase for patients experiencing posterior circulation ischemic strokes between 45 and 24 hours after symptom onset.
  • Results showed that patients receiving alteplase had a higher rate of functional independence at 90 days compared to those receiving standard medical treatment (89.6% vs. 72.6%).
  • However, increased risks were noted, with 17% of the alteplase group experiencing symptomatic intracranial hemorrhage and a higher mortality rate (52%) compared to the standard treatment group (85%).

Top posts

Most liked on X and Bluesky
NEJM
@NEJM · X

Phil, maybe someday

Jul 15, 2025 · 352 likes · 58 shares · 935,653 followers View post →
Mica Schachter, MD
@neurona_critica · X

Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 6, 2025 · 206 likes · 46 shares · 3,139 followers View post →
NEJM
@NEJM · X

Original Article: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours (EXPECTS trial) https://t.co/LFehxP9GsK #Neurology https://t.co/RRzSDWY0lp

Apr 5, 2025 · 72 likes · 24 shares · 935,653 followers View post →
NEJM.org
@nejm.org · Bluesky

Phil, maybe someday

Jul 15, 2025 · 45 likes · 6 shares View post →
ひ
@jinzou_ · X

tpaは4.5h以内という常識が覆るな。後で精読しよう。 https://t.co/FymKYGbLc0

Apr 24, 2025 · 15 likes · 1,175 followers View post →
ACCP CRIT PRN
@accpcritprn · X

Is it time to broaden the window? Patients with posterior stroke, who did not received mechanical thrombectomy and received alteplase 4.5 to 24 hours post symptom onset had higher rates of functional independence at 90 days. https://t.co/aWYlNvyOjN

May 21, 2025 · 9 likes · 7,507 followers View post →

All mentions

Carmen Parra-Fariñas
@CarmenPFarinas · X

RT @NEJM: Phil, maybe someday

Aug 8, 2025 · 58 shares · 1,207 followers View post →
roo roo
@psycho_roo17 · X

RT @NEJM: Phil, maybe someday

Jul 29, 2025 · 58 shares · 34 followers View post →
wenli
@doughandtea · X

RT @NEJM: Phil, maybe someday

Jul 29, 2025 · 58 shares View post →
Nurse Linda
@Nonnie_Linda · X

RT @NEJM: Phil, maybe someday

Jul 25, 2025 · 58 shares · 3,310 followers View post →
cg
@NorteSur7 · X

RT @NEJM: Phil, maybe someday

Jul 24, 2025 · 58 shares · 4,654 followers View post →
Monica Murphy
@MurphyIARS · X

RT @NEJM: Phil, maybe someday

Jul 24, 2025 · 58 shares · 78 followers View post →
Gavin Preston, M.D.
@GavinPrestonMD · X

RT @NEJM: Phil, maybe someday

Jul 21, 2025 · 58 shares · 87,430 followers View post →
Billie Paschal
@TXSIMTECH · X

RT @NEJM: Phil, maybe someday

Jul 21, 2025 · 58 shares · 1,897 followers View post →
janet thoton
@janetthoton · X

RT @NEJM: Phil, maybe someday

Jul 18, 2025 · 58 shares · 922 followers View post →
Dr. Feelgood ☕️
@drgivemethenews · X

RT @NEJM: Phil, maybe someday

Jul 16, 2025 · 58 shares · 231 followers View post →
Irina Kozlova
@irina_20250715 · X

RT @NEJM: Phil, maybe someday

Jul 16, 2025 · 58 shares · 70 followers View post →
Rock
@Rockimausland · X

RT @NEJM: Phil, maybe someday

Jul 16, 2025 · 58 shares · 445 followers View post →
Micah Etter MD
@MEtterMD · X

RT @NEJM: Phil, maybe someday

Jul 16, 2025 · 58 shares · 325 followers View post →
Adam Chapman, PA-S2
@Adamvastatin · X

RT @NEJM: Phil, maybe someday

Jul 16, 2025 · 58 shares · 2 followers View post →
NEJM Journal Watch
@JWatch · X

RT @NEJM: Phil, maybe someday

Jul 16, 2025 · 58 shares · 62,258 followers View post →
NEJM Evidence
@NEJMEvidence · X

RT @NEJM: Phil, maybe someday

Jul 16, 2025 · 58 shares · 30,914 followers View post →
Abdul M. Ssekandi, MBChB, MSc., M.A.P.S
@JC_by_AMS · X

RT @NEJM: Phil, maybe someday

Jul 16, 2025 · 58 shares · 1,125 followers View post →
Ezequiel Zaidel
@EzequielZaidel · X

RT @NEJM: Phil, maybe someday

Jul 16, 2025 · 58 shares · 2,533 followers View post →
Jaime A. Hidalgo A.
@Jhidalgoanfossi · X

RT @NEJM: Phil, maybe someday

Jul 16, 2025 · 58 shares · 1,877 followers View post →
patty
@tinleypark · X

RT @NEJM: Phil, maybe someday

Jul 16, 2025 · 58 shares · 117 followers View post →
Umar Farooq
@Umarfar1002 · X

Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours | New England Journal of Medicine https://t.co/PWe4YsquYT

Jul 16, 2025 · 44 followers View post →
Kingston
@kianboy · X

RT @NEJM: Phil, maybe someday

Jul 16, 2025 · 58 shares · 462 followers View post →
cardiac rehab
@cardiac_rehab7 · X

RT @NEJM: Phil, maybe someday

Jul 16, 2025 · 58 shares · 862 followers View post →
G Fernández Pajarín
@gferpaj · X

RT @NEJM: Phil, maybe someday

Jul 16, 2025 · 58 shares · 607 followers View post →
Evilchez
@Evilchez5 · X

RT @NEJM: Phil, maybe someday

Jul 16, 2025 · 58 shares · 199 followers View post →
Victoria Delgado
@VDelgadoGarcia · X

RT @NEJM: Phil, maybe someday

Jul 16, 2025 · 58 shares · 11,701 followers View post →
Kuchal Agadi
@AgadiKuchal · X

RT @NEJM: Phil, maybe someday

Jul 15, 2025 · 58 shares · 120 followers View post →
Kate K
@Harshmellow99 · X

RT @NEJM: Phil, maybe someday

Jul 15, 2025 · 58 shares · 152 followers View post →
Dr Lynn Rogers
@lynnrogersphd · X

RT @NEJM: Phil, maybe someday

Jul 15, 2025 · 58 shares · 549 followers View post →
Khalid Minhas, MD FACC
@minhaskh · X

RT @NEJM: Phil, maybe someday

Jul 15, 2025 · 58 shares · 11,357 followers View post →
Steph Powers
@DrSt00f · X

RT @NEJM: Phil, maybe someday

Jul 15, 2025 · 58 shares · 206 followers View post →
Diana Castrillón
@NanaCastri · X

RT @NEJM: Phil, maybe someday

Jul 15, 2025 · 58 shares · 287 followers View post →
victor a torres
@victorres345 · X

RT @NEJM: Phil, maybe someday

Jul 15, 2025 · 58 shares · 733 followers View post →
Matthew R. McKinney
@MatthewRMcKinn2 · X

RT @NEJM: Phil, maybe someday

Jul 15, 2025 · 58 shares · 90 followers View post →
bsdx
@bsdxbsdx · X

RT @NEJM: Phil, maybe someday

Jul 15, 2025 · 58 shares · 441 followers View post →
Luis
@Luis5Xv · X

RT @NEJM: Phil, maybe someday

Jul 15, 2025 · 58 shares · 277 followers View post →
Obito
@Charlstapia · X

RT @NEJM: Phil, maybe someday

Jul 15, 2025 · 58 shares · 107 followers View post →
Omelio Olazábal
@omelio_olazabal · X

RT @NEJM: Phil, maybe someday

Jul 15, 2025 · 58 shares · 2,274 followers View post →
Hany Ragy
@Hragy · X

RT @NEJM: Phil, maybe someday

Jul 15, 2025 · 58 shares · 80,394 followers View post →
Jaime (they/them)
@M_is4Mad · X

RT @NEJM: Phil, maybe someday

Jul 15, 2025 · 58 shares · 492 followers View post →
John P Erwin III MD MBA MACC (#BigPoppy )
@HeartOTXHeartMD · X

RT @NEJM: Phil, maybe someday

Jul 15, 2025 · 58 shares · 39,667 followers View post →
Gianluca Campo
@GianlucaCampo78 · X

RT @NEJM: Phil, maybe someday

Jul 15, 2025 · 58 shares · 2,377 followers View post →
Scott C. Howard
@schowardjd · X

RT @NEJM: Phil, maybe someday

Jul 15, 2025 · 58 shares · 9,795 followers View post →
Dr. Glaucomflecken
@DGlaucomflecken · X

RT @NEJM: Phil, maybe someday

Jul 15, 2025 · 58 shares · 694,832 followers View post →
Julio C Gómez Rincón
@jcgomezrincon · X

RT @NEJM: Phil, maybe someday

Jul 15, 2025 · 58 shares · 902 followers View post →
Breanna Sheldon MD MS
@bresheldon · X

RT @NEJM: Phil, maybe someday

Jul 15, 2025 · 58 shares · 513 followers View post →
Tripthi Sugumar
@SugumarTripthi · X

RT @NEJM: Phil, maybe someday

Jul 15, 2025 · 58 shares · 307 followers View post →
Karl
@karlbloomberg · X

RT @NEJM: Phil, maybe someday

Jul 15, 2025 · 58 shares · 336 followers View post →
FirstMed
@nolen1wh · X

RT @NEJM: Phil, maybe someday

Jul 15, 2025 · 58 shares · 158 followers View post →
Heather McEwen
@HeatherMcEwen3 · X

RT @NEJM: Phil, maybe someday

Jul 15, 2025 · 58 shares · 1,409 followers View post →
Nada Hassib
@NadaHassib1 · X

RT @NEJM: Phil, maybe someday

Jul 15, 2025 · 58 shares · 765 followers View post →
NEJM
@NEJM · X

Phil, maybe someday

Jul 15, 2025 · 352 likes · 58 shares · 935,653 followers View post →
Giacomo Urbinati
@GiacomoUrbinati · X

Thrombolysis in patients with posterior circulation stroke in 4.5-24 hours time-window https://t.co/AYJUWrJOMq

Jul 15, 2025 · 22 followers View post →
NEJM.org
@nejm.org · Bluesky

Phil, maybe someday

Jul 15, 2025 · 45 likes · 6 shares View post →
SCCM Clinical Pharmacy and Pharmacology Section
@SCCM_CPP · X

#CPPPLU Highlights: The EXPECTS Trial from @NEJM evaluated the safety and efficacy of alteplase between 4.5 to 24 hours after posterior circulation ischemic stroke. Treatment resulted in increased frequency of functional independence at 90 days. #PharmICU https://t.co/0ZI2nWQUvR https://t.co/sxFDdbFUBi

Jun 25, 2025 · 7 likes · 2 shares · 3,417 followers View post →
Elena Becker-Barroso
@beckerbarroso · X

Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours | New England Journal of Medicine https://t.co/EmN2ofAesn

May 30, 2025 · 977 followers View post →
Andy Webb
@AJWPharm · X

Next up: Kayleigh Yaeger, PharmD, PGY2 CC from UPMC is presenting Alteplase for posterior circulation ischemic stroke at 4.5 to 24 hours – The EXPECTS Trial #NCSPharmJC https://t.co/zMoLEMufP6

May 23, 2025 · 4 likes · 6,509 followers View post →
am namu
@umetotetsu · X

「発症後4.5時間から24時間の間にアルテプラーゼを投与された後方循環虚血性脳卒中患者は、標準治療を受けた患者と比較して、90日後の機能的自立が高く認められる。」後方循環系はrt-PA後の出血リスクが低い、と言われても血出た時のダメージがデカすぎてビビっちゃうんだぁよhttps://t.co/tktIWpjhps

May 23, 2025 · 58 followers View post →
ACCP CRIT PRN
@accpcritprn · X

Is it time to broaden the window? Patients with posterior stroke, who did not received mechanical thrombectomy and received alteplase 4.5 to 24 hours post symptom onset had higher rates of functional independence at 90 days. https://t.co/aWYlNvyOjN

May 21, 2025 · 9 likes · 7,507 followers View post →
茨城の「墨子」に俺はなる!ひたちなかGIM:柴﨑俊一
@sn1shibazaki · X

素人感覚では、結構インパクトのあるNEJM論文だと思うけれど、専門家はどう感じるのだろう。ガイドラインに影響するのかな(しそうな気はするけれど) https://t.co/ly6BwHxdoE 血栓除去術を受けなかった主に「軽度の」「後方循環系」の #脳梗塞

May 2, 2025 · 3 likes · 7,268 followers View post →
Revista MFAndalucia
@RevistaMFSamfyc · X

Alteplasa entre 4,5 a 24 h tras el ictus isquémico de circulación posterior https://t.co/44l20GFZEq PMID 40174223

May 1, 2025 · 722 followers View post →
KIIKAI AMEO
@1AYhsLMhJQQrg8p · X

RT @sasuraiNS: 【後方循環脳梗塞に対するtPAの効果を調べたRCT】 軽症例(NIHSS中央値3、中国人患者)に対し、 発症4.5〜24時間後のtPA静注は標準治療より90日後自立率を改善(89.6% vs 72.6%、P=0.01)。 sICH 1.…

Apr 26, 2025 · 1 share · 46 followers View post →
さすらい脳外科医
@sasuraiNS · X

【後方循環脳梗塞に対するtPAの効果を調べたRCT】 軽症例(NIHSS中央値3、中国人患者)に対し、 発症4.5〜24時間後のtPA静注は標準治療より90日後自立率を改善(89.6% vs 72.6%、P=0.01)。 sICH 1.7%、死亡率も低下傾向。 https://t.co/MowJloY7Df #脳卒中 #脳梗塞 #tPA #Stroke

Apr 25, 2025 · 6 likes · 1 share · 872 followers View post →
岩手医科大学 脳神経内科・老年科
@IwateNeurol · X

4.5-24時間のMT施行しなかった後方循環脳梗塞へのIVTPAのRCT@中国.まだ精読していませんがこんなに効くとは驚きです.https://t.co/NvxUKDukP8

Apr 25, 2025 · 3 likes · 1,019 followers View post →
岩手医科大学 脳神経内科・老年科
@IwateNeurol · X

RT @AshuPJadhav: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours | New England Journal of Medicine https://t.co/9A52…

Apr 25, 2025 · 151 shares · 1,019 followers View post →
Shicheng Guo
@ShihchengGuo · X

Study: Alteplase was given 4.5-24h post-onset to patients with posterior circulation ischemic stroke in China. Trials show promise! Dose: 0.9 mg/kg, max 90 mg. #StrokeResearch PMID:40174223, N Engl J Med 2025, @NEJM @Stanford https://t.co/WEWha3swci #AI #Pharma #BioMed #RNA #ASHG

Apr 25, 2025 · 499 followers View post →
Sophia Crawford
@Crawford2Sophia · X

RT @NEJM: Original Article: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours (EXPECTS trial) https://t.co/LFehxP9GsK…

Apr 24, 2025 · 24 shares · 118 followers View post →
ひ
@jinzou_ · X

tpaは4.5h以内という常識が覆るな。後で精読しよう。 https://t.co/FymKYGbLc0

Apr 24, 2025 · 15 likes · 1,175 followers View post →
ASHOK SJ
@Sachinashok · X

Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours | New England Journal of Medicine https://t.co/3FYG7pJ78n

Apr 22, 2025 · 88 followers View post →
STITCHES Medicine - the Best of Medical Research
@medicine.stitches.today · Bluesky

Alteplase significantly improved functional independence in patients with posterior circulation stroke after 4.5 to 24 hours compared to standard care. by Yan S, Zhou Y (...) Lou M et 20 al. in N Engl J Med #MedSky

Apr 12, 2025 · 5 likes · 1 share View post →
STITCHES Medicine - the Best of Medical Research
@STITCHESMed · X

Alteplase significantly improved functional independence in patients with posterior circulation stroke after 4.5 to 24 hours compared to standard care. by Yan S, Zhou Y (...) Lou M et 20 al. in N Engl J Med https://t.co/mvow9qhE2M #MedX #MedResearch

Apr 12, 2025 · 83 followers View post →
UCLA Stroke Center
@UCLAStroke · X

RT @UCLANeurology: Can alteplase still help beyond the 4.5-hour post-stroke window? Dr. David Liebeskind finds that even after the traditi…

Apr 10, 2025 · 1 share · 646 followers View post →
UCLA Stroke Center
@UCLAStroke · X

Patients with mild posterior circulation strokes and who did not receive thrombectomy may benefit from alteplase administration at 4.5 to 24h after onset. Dr. David Liebeskind published a deeper investigation into alteplase after 4.5h! https://t.co/D0QCYKi4jO

Apr 10, 2025 · 1 like · 646 followers View post →
Amparo Paredes
@AmparoP30541824 · X

RT @RafaelReyes_MD:

Apr 10, 2025 · 117 shares · 41 followers View post →
UCLA Neurology
@UCLANeurology · X

Can alteplase still help beyond the 4.5-hour post-stroke window? Dr. David Liebeskind finds that even after the traditional cutoff, alteplase may improve functional independence compared to standard care for #stroke. https://t.co/EBkbSZFQL6 https://t.co/vlbV0AOCQA

Apr 10, 2025 · 9 likes · 1 share · 4,490 followers View post →
M Azfar Qureshi
@MAQ_Renal · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 9, 2025 · 46 shares · 164 followers View post →
octavio
@dontavo66 · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 8, 2025 · 46 shares · 331 followers View post →
PubMed Trending
@PubTrend · X

Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours. https://t.co/elTAMN5dzy

Apr 8, 2025 · 5,160 followers View post →
mia
@mia71343443 · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 8, 2025 · 46 shares · 146 followers View post →
Htet Aung Lynn
@htetaglynnn · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 8, 2025 · 46 shares · 126 followers View post →
Neurosonology, Neuroradiology & Neurophysiology
@rusneuro · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 8, 2025 · 46 shares · 115 followers View post →
juliana vera
@julianavera3 · X

RT @RafaelReyes_MD:

Apr 7, 2025 · 117 shares · 171 followers View post →
Genny Trueba
@genny_trueba · X

RT @RafaelReyes_MD:

Apr 7, 2025 · 117 shares · 103 followers View post →
Chen Yi-Hsiang
@chnyxin60095300 · X

Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours | New England Journal of Medicine https://t.co/1i2Vu9hvcG

Apr 7, 2025 · 4 followers View post →
Ingridlly
@Ingridlly · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 7, 2025 · 46 shares · 187 followers View post →
린라다.
@nonuiscalling · X

RT @NEJM: Original Article: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours (EXPECTS trial) https://t.co/LFehxP9GsK…

Apr 7, 2025 · 24 shares · 42 followers View post →
Andrea Baquerizo
@BaqueSisi · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 7, 2025 · 46 shares · 63 followers View post →
Nima Amini, M.D.
@_NimaAmini · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 7, 2025 · 46 shares · 249 followers View post →
sharma14828
@sharma14828 · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 7, 2025 · 46 shares · 37,769 followers View post →
Dr. Mike
@mybarra · X

New data in @NEJM abt Alteplase for Posterior Circulation Stroke at 4.5-24 Hrs. Posterior stroke symptoms: -Dizziness, nausea, vomiting, vertigo, visual disturbances, balance issues. Remember: early dx and tx is key. Call 911 if you experience these sx. https://t.co/2Qjyu43lli

Apr 7, 2025 · 621 followers View post →
Jorge Celis Mejia
@JorgeCelisM · X

RT @AshuPJadhav: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours | New England Journal of Medicine https://t.co/9A52…

Apr 7, 2025 · 151 shares · 246 followers View post →
Julian mauricio Baez
@jbaez311 · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 7, 2025 · 46 shares · 29 followers View post →
Helga
@Aisha12895124 · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 7, 2025 · 46 shares · 4,398 followers View post →
PubMed Trending
@PubTrend · X

Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours. https://t.co/elTAMN5dzy

Apr 7, 2025 · 5,160 followers View post →
Dr. Joshuan J. Barboza
@joshuanbarbozam · X

RT @NEJM: Original Article: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours (EXPECTS trial) https://t.co/LFehxP9GsK…

Apr 7, 2025 · 24 shares · 10,054 followers View post →
Richard Choi, DO, FNCS
@rkchoi · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 7, 2025 · 46 shares · 3,795 followers View post →
Kevin
@Kevin_Use11 · X

RT @NEJM: Original Article: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours (EXPECTS trial) https://t.co/LFehxP9GsK…

Apr 7, 2025 · 24 shares · 14 followers View post →
RAD MAN
@RADMAN82020482 · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 7, 2025 · 46 shares · 425 followers View post →
Charles JC
@charlesjc41193 · X

RT @AshuPJadhav: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours | New England Journal of Medicine https://t.co/9A52…

Apr 7, 2025 · 151 shares · 422 followers View post →
Charles JC
@charlesjc41193 · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 7, 2025 · 46 shares · 422 followers View post →
ふろりあん
@ems4jhondo · X

Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours | New England Journal of Medicine https://t.co/ZOrm8FrkIW

Apr 7, 2025 · 1,069 followers View post →
Dr.Félix09Rodríguez
@PhellixR · X

RT @NEJM: Original Article: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours (EXPECTS trial) https://t.co/LFehxP9GsK…

Apr 7, 2025 · 24 shares · 1,354 followers View post →
DR HOUSE
@SHINEYAGGARWAL · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 7, 2025 · 46 shares · 488 followers View post →
Syed Shahrul Naz
@drshahrul80 · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 7, 2025 · 46 shares · 6,931 followers View post →
Flotta Dura Senza Paura
@flottadura · X

RT @NEJM: Original Article: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours (EXPECTS trial) https://t.co/LFehxP9GsK…

Apr 7, 2025 · 24 shares · 314 followers View post →
octavio
@dontavo66 · X

RT @NEJM: Original Article: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours (EXPECTS trial) https://t.co/LFehxP9GsK…

Apr 7, 2025 · 24 shares · 331 followers View post →
betül kozanhan
@betulkozanhan · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 7, 2025 · 46 shares · 274 followers View post →
lehealerr7
@lehealer7 · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 7, 2025 · 46 shares · 9 followers View post →
Faheem Sheriff
@faheem_sheriff · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 7, 2025 · 46 shares · 123 followers View post →
NeuroIR
@neuro_ir · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 6, 2025 · 46 shares · 825 followers View post →
Suazo
@DrCerros · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 6, 2025 · 46 shares · 33 followers View post →
Dr.Muneeb Yusuf
@MuneebDr · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 6, 2025 · 46 shares · 370 followers View post →
Marina Vilardo, MD
@MVilardoMD · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 6, 2025 · 46 shares · 358 followers View post →
Martín Vilema
@MartinVilema · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 6, 2025 · 46 shares · 223 followers View post →
Samir Abu Rumeileh
@s_rumeileh · X

RT @NEJM: In patients with posterior circulation stroke for whom thrombectomy was not planned, alteplase administered 4.5 to 24 hours after…

Apr 6, 2025 · 34 shares · 138 followers View post →
Cristina Toro
@CristinaToro5 · X

RT @NEJM: Original Article: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours (EXPECTS trial) https://t.co/LFehxP9GsK…

Apr 6, 2025 · 24 shares · 220 followers View post →
Diógenes Zan
@Diogenes_Zan · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 6, 2025 · 46 shares · 204 followers View post →
Yeray Aguilar
@YerayAguilar · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 6, 2025 · 46 shares · 1,829 followers View post →
旅人 tabito
@tabibito250 · X

Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours | New England Journal of Medicine https://t.co/f5TFtrpicg

Apr 6, 2025 · 1 like · 1,066 followers View post →
healthyanddiet
@healthyanddiet1 · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 6, 2025 · 46 shares · 94 followers View post →
drpaulinosegundo
@drpaulinosegun1 · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 6, 2025 · 46 shares · 141 followers View post →
Juan Maza
@JuanMaz09467209 · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 6, 2025 · 46 shares · 103 followers View post →
Sweety Trivedi
@Trivedi4Sweety · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 6, 2025 · 46 shares · 38 followers View post →
juan lopez
@jd1lopez · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 6, 2025 · 46 shares · 1,074 followers View post →
Timothy Ellender, MD, FCCM
@tjelle13 · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 6, 2025 · 46 shares · 2,264 followers View post →
A͎l͎e͎x͎a͎n͎d͎r͎a͎
@karlasklein · X

RT @RafaelReyes_MD:

Apr 6, 2025 · 117 shares · 972 followers View post →
CHN390 MD
@cihan390 · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 6, 2025 · 46 shares · 990 followers View post →
lucasdario
@lucasdario3 · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 6, 2025 · 46 shares · 136 followers View post →
Mohammad Aleidi
@aleidimed · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 6, 2025 · 46 shares · 300 followers View post →
Maria Giulia Mosconi
@mgiulia_mosconi · X

RT @NEJM: Original Article: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours (EXPECTS trial) https://t.co/LFehxP9GsK…

Apr 6, 2025 · 24 shares · 122 followers View post →
PubMed Trending
@PubTrend · X

Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours. https://t.co/elTAMN5dzy

Apr 6, 2025 · 5,160 followers View post →
neurodoctor
@neurodoctor4 · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 6, 2025 · 46 shares · 246 followers View post →
Neurocriticals S.C
@arauz_edil45909 · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 6, 2025 · 46 shares · 12 followers View post →
Neuro Criticos
@neurointensivos · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 6, 2025 · 46 shares · 2,815 followers View post →
Gustavo Domeniconi
@gdomeni · X

RT @neurona_critica: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 6, 2025 · 46 shares · 906 followers View post →
Wasili Carrillo
@DrWasili · X

RT @NEJM: Original Article: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours (EXPECTS trial) https://t.co/LFehxP9GsK…

Apr 6, 2025 · 24 shares · 1,812 followers View post →
Dumisani Mfipa
@dumisanimfipa · X

RT @NEJM: Original Article: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours (EXPECTS trial) https://t.co/LFehxP9GsK…

Apr 6, 2025 · 24 shares · 186 followers View post →
Mica Schachter, MD
@neurona_critica · X

Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/UySZEEDBgs https://t.co/lj4RKeslXQ

Apr 6, 2025 · 206 likes · 46 shares · 3,139 followers View post →
Powell Kafwanka, MBChB, MSc
@PowellKafwanka · X

RT @NEJM: Original Article: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours (EXPECTS trial) https://t.co/LFehxP9GsK…

Apr 6, 2025 · 24 shares · 93 followers View post →
Dr.Eidah M AlThomali
@wikiicu · X

RT @NEJM: Original Article: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours (EXPECTS trial) https://t.co/LFehxP9GsK…

Apr 6, 2025 · 24 shares · 135 followers View post →
pinacol
@pinacol · X

【RCT】CT上早期の広範囲の低吸収域がなく、血栓除去術が予定されていない後方循環系脳梗塞患者への発症後4.5から24時間でのアルテプラーゼの投与は、標準治療と比較して、90日時点での機能的自立達成を増加させた。 #ペ読 https://t.co/POJMxE91Ux

Apr 6, 2025 · 2 likes · 1,617 followers View post →
Menelas Nkeshimana
@mnls_nke · X

RT @NEJM: Original Article: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours (EXPECTS trial) https://t.co/LFehxP9GsK…

Apr 6, 2025 · 24 shares · 4,134 followers View post →
พาโรม่า! ft.ผับอัลเกิร์ล III
@Fame_PE0810 · X

RT @NEJM: Original Article: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours (EXPECTS trial) https://t.co/LFehxP9GsK…

Apr 5, 2025 · 24 shares · 228 followers View post →
Roberto Lugo
@RobertoLG86MI · X

RT @RafaelReyes_MD:

Apr 5, 2025 · 117 shares · 54 followers View post →
Manuel Tapias Agamez
@manetapias · X

RT @NEJM: Original Article: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours (EXPECTS trial) https://t.co/LFehxP9GsK…

Apr 5, 2025 · 24 shares · 109 followers View post →
Muhammad Adrish, MD, MBA
@AdrishMD · X

RT @NEJM: Original Article: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours (EXPECTS trial) https://t.co/LFehxP9GsK…

Apr 5, 2025 · 24 shares · 621 followers View post →
Sameer Ahmed
@SameerA41115539 · X

RT @NEJM: Original Article: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours (EXPECTS trial) https://t.co/LFehxP9GsK…

Apr 5, 2025 · 24 shares · 997 followers View post →
Taylor Louis
@TaylorLoui30289 · X

RT @NEJM: Original Article: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours (EXPECTS trial) https://t.co/LFehxP9GsK…

Apr 5, 2025 · 24 shares · 39 followers View post →
TH@疫学
@pon144 · X

RT @NEJM: Original Article: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours (EXPECTS trial) https://t.co/LFehxP9GsK…

Apr 5, 2025 · 24 shares · 445 followers View post →
Gema Tirado - Conde, MD, PhD
@BlossonSimonds · X

RT @NEJM: Original Article: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours (EXPECTS trial) https://t.co/LFehxP9GsK…

Apr 5, 2025 · 24 shares · 947 followers View post →
Antônio Augusto Moreira Barbosa
@gugumoreirab2 · X

RT @NEJM: Original Article: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours (EXPECTS trial) https://t.co/LFehxP9GsK…

Apr 5, 2025 · 24 shares · 94 followers View post →
Daniel Jafari
@DanielJafari · X

EXPECTS trial results out. In post fossa ischemic stroke 4.5-24hrs with no intervention planned, neurologic outcomes improved. Rates of parenchymal hemorrhage w tpa x2 but still pretty low at 1.7% https://t.co/zIJHxXYcME

Apr 5, 2025 · 2,195 followers View post →
NEJM
@NEJM · X

Original Article: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours (EXPECTS trial) https://t.co/LFehxP9GsK #Neurology https://t.co/RRzSDWY0lp

Apr 5, 2025 · 72 likes · 24 shares · 935,653 followers View post →
Manuel
@manusefir · X

RT @PubTrend: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours. https://t.co/elTAMN5dzy

Apr 5, 2025 · 1 share · 539 followers View post →
Eric Stulberg
@elstulberg1 · X

RT @AshuPJadhav: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours | New England Journal of Medicine https://t.co/9A52…

Apr 5, 2025 · 151 shares · 421 followers View post →
Samantha Fernandez, MD
@DrSamanthaF · X

RT @AshuPJadhav: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours | New England Journal of Medicine https://t.co/9A52…

Apr 5, 2025 · 151 shares · 2,378 followers View post →
juniorjuri
@juniorjuri · X

RT @Nigelj08223326: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/VO4G1GMYkn alteplase administered…

Apr 5, 2025 · 1 share · 1,489 followers View post →
Truthoverdishonesty
@Nigelj08223326 · X

Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours https://t.co/VO4G1GMYkn alteplase administered 4.5 to 24 hours after stroke onset resulted higher frequency of functional independence at 90 days than standard medical care @juniorjuri @Michell24423236 https://t.co/EIg1NOiMK2

Apr 5, 2025 · 3 likes · 1 share · 1,608 followers View post →
Mohammad Aleidi
@aleidimed · X

RT @GhannamMalik: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours | New England Journal of Medicine https://t.co/yuV…

Apr 5, 2025 · 8 shares · 300 followers View post →
PubMed Trending
@PubTrend · X

Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours. https://t.co/elTAMN5dzy

Apr 5, 2025 · 1 share · 5,160 followers View post →
Medicina Eterna
@Fvelaz · X

RT @RafaelReyes_MD:

Apr 5, 2025 · 117 shares · 301 followers View post →
@JuanpaElProfeee
@juanpaesculapio · X

RT @RafaelReyes_MD:

Apr 5, 2025 · 117 shares · 1,228 followers View post →
Huda Saleh
@HistHumorDoc · X

RT @ZHeart11768530:

Apr 5, 2025 · 25 shares · 7 followers View post →
crocodil
@OlennaBatir · X

RT @AshuPJadhav: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours | New England Journal of Medicine https://t.co/9A52…

Apr 5, 2025 · 151 shares · 54 followers View post →
Ros
@RosembergP33633 · X

RT @ZHeart11768530:

Apr 5, 2025 · 25 shares · 32 followers View post →
GHAZALI, M.D
@MGhazali225 · X

RT @ZHeart11768530:

Apr 5, 2025 · 25 shares · 157 followers View post →
juliana vera
@julianavera3 · X

RT @AshuPJadhav: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours | New England Journal of Medicine https://t.co/9A52…

Apr 4, 2025 · 151 shares · 171 followers View post →
Sarah Nelson, MD, MPH, FAAN, FNCS
@senelson13 · X

RT @AshuPJadhav: Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours | New England Journal of Medicine https://t.co/9A52…

Apr 4, 2025 · 151 shares · 1,196 followers View post →
PubMed Trending
@PubTrend · X

Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours. https://t.co/elTAMN5dzy

Apr 4, 2025 · 5,160 followers View post →
BaladoCritique : club de lecture médical
@baladocritique.bsky.social · Bluesky

"Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours." Étude chinoise EXPECTS, publiée ce jour dans le @nejm.org. #MedSky #NeuroSky #Stroke www.nejm.org/doi/full/10....

Apr 3, 2025 View post →
kmatsuo
@kkmatsuo.bsky.social · Bluesky

Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours | New England Journal of Medicine www.nejm.org/doi/full/10....

Apr 2, 2025 · 2 likes View post →