Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin America and the Caribbean.

Talia Wegman-Ostrosky, Lucia Taja-Chayeb, Zyanya Lucia Zatarain-Barrón, Catalina Trejo-Becerril, Alfredo Ramirez-Gonzalez, Jimena Romo-Huerta, Lisa Ximena Rodriguez-Rojas, Isabel Espino-Gutiérrez, Zacil Ha Vilchis-Zapata, Sylvia Harari-Arakindji, José Elías García-Ortiz, Alejandro Ruiz-Patiño

April 2025 JCO Glob Oncol

Synopsis of Social media discussions

Discussions highlight the article's detailed synthesis of hereditary cancer research specific to Latin America and the Caribbean, with expressions like 'most comprehensive' and 'offers the most synthesis' indicating high regard. The tone is enthusiastic and appreciative, emphasizing the importance of region-tailored genetic data, which demonstrates strong interest and engagement but moderate perceived broader impact.

A
Agreement
 Moderate agreement

Most discussions highly praise the article, emphasizing its comprehensive nature and relevance to regional health disparities.

I
Interest
 High level of interest

The use of words like 'outstanding,' 'most comprehensive,' and 'must read' shows strong interest and appreciation for the research.

E
Engagement
 High engagement

Participants reference the scope of the review and its implications, indicating deep engagement with the topic.

I
Impact
 Moderate level of impact

While the posts suggest the article could influence regional cancer care, the overall perceived impact seems moderate, focused on advancing regional genetics research.

Social Mentions

YouTube

1 Videos

Twitter

47 Posts

TikTok

5 Posts

Metrics

Video Views

93

Total Likes

106

Extended Reach

82,312

Social Features

53

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

Genetic Variants and Hereditary Cancer Risks in Latin America and the Caribbean

Genetic Variants and Hereditary Cancer Risks in Latin America and the Caribbean

This video discusses germline genetic variants associated with cancer predisposition in Latin American and Caribbean patients. It emphasizes region-specific data to improve personalized cancer prevention, treatment, and management in these populations.

Oncogenetica Lisa Rodriguez

April 20, 2025

93 views

  • Marina Romero
    @MarinaR69714826 (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 26, 2025

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  • Wagner Parra-Paladines
    @WagnerParra2 (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 22, 2025

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  • Juan E. Garcia-Robledo, M.D.
    @JuanEGarciaMD (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 21, 2025

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    @OM3d_ (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 21, 2025

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  • Benjamin Walbaum, MD
    @benjiwal (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 21, 2025

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  • Suzanne Kazandjian
    @S_Kazandjian (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 21, 2025

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  • nel cuevas muñoz
    @MunozNel (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 21, 2025

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  • Veronica Salais Michaus
    @MichausSalais (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 21, 2025

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  • Joel YR
    @YnfaYr (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    @leogilsan (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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  • Intel
    @IntelMedicine (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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  • Vinícius Lorandi
    @iamLorandi (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 20, 2025

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  • Javier David Benitez Fuentes
    @JavierDavidBen2 (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 20, 2025

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  • William_Mantilla
    @wilar79 (Twitter)

    RT @MLPOncoData: Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin America and the Caribbean https://t.co/3vT…
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    April 20, 2025

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  • Xema Pérez
    @Xemadeyaka14 (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 20, 2025

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    @CeprecOaxaca (Twitter)

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    @diacavan (Twitter)

    RT @MLPOncoData: Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin America and the Caribbean https://t.co/3vT…
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    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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  • Paul Vargas
    @paulvargasonco (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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  • Gonzalo Bentolila
    @GonzaloBentoli1 (Twitter)

    RT @XimeJordan: Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin America and the Caribbean | JCO Global Onco…
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    April 20, 2025

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  • Ximena Jordan Bruno
    @XimeJordan (Twitter)

    Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin America and the Caribbean | JCO Global Oncology https://t.co/vjamkvhP4T
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  • Carlos Gonzalez
    @DrMedOnco (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 20, 2025

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  • Jennifer A. Marks, MD
    @jennifermarksmd (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 20, 2025

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  • Michael Serzan, MD
    @MikeSerzanMD (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 20, 2025

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  • @CParkMD (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 20, 2025

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  • Patxi Queipo
    @patxiqueipo (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 20, 2025

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  • Seekriz Den
    @SikritD (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 20, 2025

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  • Dr NAVDEEP SINGH DM ( AIIMS ) New Delhi
    @myfight4cancer (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 20, 2025

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  • Stetson
    @stetson_thacker (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 19, 2025

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  • Ignacio Sanchez
    @sedoreh (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 19, 2025

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  • Victoria Gálvez
    @victoriagalvezp (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 19, 2025

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  • Fernanda Dias
    @fcdias1 (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 19, 2025

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  • Cancer Center Informatics Society
    @CI4CC (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 19, 2025

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  • David Heredia.
    @HerediaOncologo (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 19, 2025

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    @mortimerarreaza (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 19, 2025

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  • Almansour
    @malmansour81 (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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  • Charles Dariane
    @CharlesDariane (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 19, 2025

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  • Leandro Jonata Oliveira
    @LeandroJonatad1 (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 19, 2025

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  • Ximena A. Rios Peña PhD SP, Msc Epi
    @Quelafuerzatea1 (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 19, 2025

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  • Andres Ossa
    @tumastologo1 (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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  • Ossian Longoria
    @OssianLongoria (Twitter)

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    @AndresFCardonaZ (Twitter)

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  • Andres F. Cardona
    @AndresFCardonaZ (Twitter)

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  • MLP Oncología
    @MLPOncoData (Twitter)

    Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin America and the Caribbean https://t.co/3vTOMdvaFS
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  • Luis Eduardo Pino V
    @docpinoAI (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 19, 2025

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  • Angelo Dipasquale
    @AngeloDipa_ (Twitter)

    RT @OscarTahuahua: Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin Americ…
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    April 19, 2025

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  • Oscar Tahuahua
    @OscarTahuahua (Twitter)

    Outstanding review in @JCO_ASCO - Germline Genetic Variants in Cancer Predisposition Genes in Patients From Latin America and the Caribbean. Offers the most comprehensive synthesis on hereditary cancer in LAC, by @taliawegman et al.
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    April 19, 2025

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  • Milexis Claret Trejos Rodriguez | TikTok

    doi: 10.1200/GO-24-00433. Epub 2025 Apr 18. PMID: 40249889. #CancerDeMama #BRCA3 #InvestigaciónCientífica #Genetica #TrabajoEnEquipo #NuevoArtículo #BRCA1 ...
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    December 16, 2025

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  • Cindy Lorena Trejos Ortiz Oficial | TikTok

    doi: 10.1200/GO-24-00433. Epub 2025 Apr 18. PMID: 40249889. #CancerDeMama #BRCA3 #InvestigaciónCientífica #Genetica #TrabajoEnEquipo ...
    view full post

    November 17, 2025

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  • Zaira Patino Trejo | TikTok

    doi: 10.1200/GO-24-00433. Epub 2025 Apr 18. PMID: 40249889. #CancerDeMama #BRCA3 #InvestigaciónCientífica #Genetica #TrabajoEnEquipo ...
    view full post

    October 27, 2025

    TikTok

  • La Citogenética: Clave en la Medicina Moderna y Cáncer | TikTok

    doi: 10.1200/GO-24-00433. Epub 2025 Apr 18. PMID: 40249889. #CancerDeMama #BRCA3 #InvestigaciónCientífica #Genetica #TrabajoEnEquipo ...
    view full post

    July 26, 2025

    TikTok

  • Resultados de pruebas genéticas para el cáncer hereditario | TikTok

    doi: 10.1200/GO-24-00433. Epub 2025 Apr 18. PMID: 40249889. #CancerDeMama #BRCA3 #InvestigaciónCientífica #Genetica #TrabajoEnEquipo ...
    view full post

    July 2, 2025

    TikTok

Abstract Synopsis

  • The article emphasizes the need for region-specific health data in Latin America and the Caribbean (LAC) to improve cancer prevention, treatment, and management, since current guidelines are often based on data from North America, Europe, and Asia.
  • Over 20% of global cancer cases occur in LAC, but research and medical practices tailored specifically to this population are limited; emerging genetic information aims to fill this gap.
  • The review highlights differences in germline genetic variants linked to hereditary cancer syndromes in LAC populations, including unique founder and recurrent variants, which could influence personalized cancer care in the region.