JACC Adv July 2025 PMID 40450909

Reply: The Keto CTA Study.

Adrian Soto-Mota, Nicholas G Norwitz, Venkat S Manubolu, April Kinninger, Thomas R Wood, James Earls, David Feldman, Matthew Budoff

Mentions

50
Peak: 43 in May 2025
across 4 sources since May 2025

Extended reach

335,700
potential audience

Total likes

1,329

Video views

23,087

Mentions per month

May 2025 – Oct 2025

Where it's discussed

  • X / Twitter42 posts
  • YouTube3 videos
  • News3 articles
  • Blogs2 articles

AI synopsis

What people are saying

The comments include technical references to specific calculations and methodological choices, such as the distinction between median percent change and individual percentage changes, signaling a deeper interest in the validity and precision of the study. Tone varies from neutral reporting to mild critique, contributing to a balanced perception that values detailed engagement over emotional bias.

AgreementNeither agree nor disagree

The discussions show some support for the research, but also acknowledge conflicting interpretations and methodological details, indicating neither strong agreement nor disagreement overall.

InterestModerate interest

There is a general moderate interest, with some posts sharing links, summaries, and addressing specific points like statistical methods and implications, suggesting curiosity about the study's findings and context.

EngagementModerate engagement

Several discussions involve detailed references to statistical calculations, methodological debates, and responses to editorial processes, showing a decent level of deep engagement rather than superficial reactions.

ImpactNeutral impact

The impact appears moderate since the discussions revolve around clarifying details, challenging figures, and responding to scholarly exchange, rather than indicating a widespread transformative perception of the publication.

Top posts

Most liked on X and Bluesky
Michael Albert, MD
@MichaelAlbertMD · X

May 8, 2025 · 99 likes · 27 shares · 15,925 followers View post →
Nick Norwitz MD PhD
@nicknorwitz · X

11/11) For an easy-read version of the thread, with hyperlinks and a bit more information, see: https://t.co/rqNlHe2WFw For our LTE response letter: https://t.co/Igb52P4f2M For the Open Access Table: https://t.co/8ThyubFPPw For the Podcast with Chris @VivaLongevity and Dave:

May 8, 2025 · 61 likes · 6 shares · 109,058 followers View post →
Christoffer Baustad Nilsen
@ChristofferBN · X

Excuse me? Some? 95 out of 100 of them... https://t.co/7RkYSignkT https://t.co/X0kAm6xwSP

May 8, 2025 · 19 likes · 585 followers View post →
Dave Feldman
@realDaveFeldman · X

Needless to say it has felt like an eternity while we were working through the process with the journal -- but to be fair to them, it was an eternity in Internet Time(tm) Here's the reply to LTE:https://t.co/zEpXo9SUdk And below is linked my new thread on our study/steps ahead https://t.co/LPMUkDQXIm

May 8, 2025 · 14 likes · 1 share · 84,363 followers View post →
Dr Anna Borek
@Pl4ntbased · X

https://t.co/mQA5rN0Hti The value above = the median percent change in NCPV (I calculated the percent change for all participants and then calculated the median of those values). The authors have given a value of 42.8. But they calculated this using the median change and the

May 8, 2025 · 13 likes · 1,128 followers View post →
GladstoneBrookes
@GladstoneB81859 · X

Note that this differs from the figure of 42.8% given in the letter by Soto-Mota et al. as they calculate the median increase relative to the median baseline, and not the median of individual percentage changes, which I believe is a superior metric. https://t.co/GzxnCZUDae https://t.co/JTTNdZnine

May 8, 2025 · 8 likes · 1 share · 529 followers View post →

All mentions

CopperKettle
@Artyom_Yekat · X

RT @MichaelAlbertMD:

May 14, 2025 · 27 shares · 378 followers View post →
Seraphim Angels
@SeraphimAngels1 · X

RT @nicknorwitz: 11/11) For an easy-read version of the thread, with hyperlinks and a bit more information, see: https://t.co/rqNlHe2WFw F…

May 13, 2025 · 6 shares · 324 followers View post →
Zed
@zz_2141 · X

@Pl4ntbased https://t.co/aIhrX8M2WM Their letter does admit that results are compatible with ApoB being causal (but not as part of paper). Most proponents of lipid hypothesis expected rapid plaque growth in this cohort, which turned out to be true. It was actually much faster than expected. https://t.co/KK1cOUNbhb

May 13, 2025 · 8 likes · 105 followers View post →
ac2r3ad
@ac2r3ad · X

RT @MichaelAlbertMD:

May 10, 2025 · 27 shares · 106 followers View post →
Dr Tom Butler
@drtom_butler · X

RT @MichaelAlbertMD:

May 10, 2025 · 27 shares · 3,410 followers View post →
United Realist
@unitedrealist2 · X

RT @MichaelAlbertMD:

May 10, 2025 · 27 shares · 61 followers View post →
J-Rod
@whohead1 · X

RT @MichaelAlbertMD:

May 9, 2025 · 27 shares · 549 followers View post →
Slawomir
@Slawomi18369321 · X

RT @MichaelAlbertMD:

May 9, 2025 · 27 shares · 84 followers View post →
Mind Your Science!
@MindYourSci · X

RT @MichaelAlbertMD:

May 9, 2025 · 27 shares · 134 followers View post →
Paper Ballot
@WhiteRat1776 · X

RT @nicknorwitz: 11/11) For an easy-read version of the thread, with hyperlinks and a bit more information, see: https://t.co/rqNlHe2WFw F…

May 9, 2025 · 6 shares · 2,505 followers View post →
Colleen Griffith
@Griffith17431 · X

RT @MichaelAlbertMD:

May 9, 2025 · 27 shares · 929 followers View post →
Continue Respirando!!!
@cerviamargo · X

RT @nicknorwitz: 11/11) For an easy-read version of the thread, with hyperlinks and a bit more information, see: https://t.co/rqNlHe2WFw F…

May 9, 2025 · 6 shares · 121 followers View post →
RojkoS
@rojko_s · X

RT @nicknorwitz: 11/11) For an easy-read version of the thread, with hyperlinks and a bit more information, see: https://t.co/rqNlHe2WFw F…

May 9, 2025 · 6 shares · 31 followers View post →
Rx Readmore Livemore
@SopitaSirirata1 · X

RT @MichaelAlbertMD:

May 9, 2025 · 27 shares · 168 followers View post →
Peter Voshol
@Peter_Voshol · X

RT @nicknorwitz: 11/11) For an easy-read version of the thread, with hyperlinks and a bit more information, see: https://t.co/rqNlHe2WFw F…

May 9, 2025 · 6 shares · 1,920 followers View post →
Christoffer Baustad Nilsen
@ChristofferBN · X

RT @MichaelAlbertMD:

May 9, 2025 · 27 shares · 585 followers View post →
cardiocdmx
@cardiocdmx · X

RT @MichaelAlbertMD:

May 8, 2025 · 27 shares · 76 followers View post →
some problem with kwangya
@Joansallen · X

RT @MichaelAlbertMD:

May 8, 2025 · 27 shares · 316 followers View post →
jenn
@911jenn · X

RT @nicknorwitz: 11/11) For an easy-read version of the thread, with hyperlinks and a bit more information, see: https://t.co/rqNlHe2WFw F…

May 8, 2025 · 6 shares · 336 followers View post →
endocrinogustavoparra
@gustavendocrino · X

LA COMUNIDAD KETO DEBE SER MUY RESPONSABLE CON EL MENSAJE QUE TRANSMITE . Especialmente con los HIPERRESPONDEDORES Reply to Letter regarding Keto CTA Study https://t.co/0146V5qk2i

May 8, 2025 · 2 likes · 13,471 followers View post →
Nancy Clark MS RD
@nclarkrd · X

RT @MichaelAlbertMD:

May 8, 2025 · 27 shares · 13,426 followers View post →
Terry Simpson
@terrysimpson · X

RT @MichaelAlbertMD:

May 8, 2025 · 27 shares · 6,263 followers View post →
Brian Ingold, DO
@DrIngold · X

RT @MichaelAlbertMD:

May 8, 2025 · 27 shares · 620 followers View post →
Adil Rashid MD
@adil_rashidk · X

RT @MichaelAlbertMD:

May 8, 2025 · 27 shares · 1,451 followers View post →
Dr Iron Junkie Ⓥ
@DrIronJunkie · X

RT @MichaelAlbertMD:

May 8, 2025 · 27 shares · 2,766 followers View post →
andres
@palacioendocrin · X

RT @MichaelAlbertMD:

May 8, 2025 · 27 shares · 354 followers View post →
Dr. Woodall
@DrWoodallND · X

RT @MichaelAlbertMD:

May 8, 2025 · 27 shares · 675 followers View post →
Dr Anna Borek
@Pl4ntbased · X

RT @MichaelAlbertMD:

May 8, 2025 · 27 shares · 1,128 followers View post →
Douglas Kalman PhD
@dougkalmanphdrd · X

RT @MichaelAlbertMD:

May 8, 2025 · 27 shares · 5,449 followers View post →
Stephanie deGiorgio
@DrSdeG · X

RT @MichaelAlbertMD:

May 8, 2025 · 27 shares · 24,813 followers View post →
Hina Chaudhry, MD
@Hinaheartdoc · X

RT @MichaelAlbertMD:

May 8, 2025 · 27 shares · 5,681 followers View post →
Beverly G. Tchang, MD
@BevTchangMD · X

RT @MichaelAlbertMD:

May 8, 2025 · 27 shares · 6,102 followers View post →
Michael Albert, MD
@MichaelAlbertMD · X

May 8, 2025 · 99 likes · 27 shares · 15,925 followers View post →
Dr Anna Borek
@Pl4ntbased · X

RT @GladstoneB81859: Note that this differs from the figure of 42.8% given in the letter by Soto-Mota et al. as they calculate the median i…

May 8, 2025 · 1 share · 1,128 followers View post →
GladstoneBrookes
@GladstoneB81859 · X

Note that this differs from the figure of 42.8% given in the letter by Soto-Mota et al. as they calculate the median increase relative to the median baseline, and not the median of individual percentage changes, which I believe is a superior metric. https://t.co/GzxnCZUDae https://t.co/JTTNdZnine

May 8, 2025 · 8 likes · 1 share · 529 followers View post →
Dr Anna Borek
@Pl4ntbased · X

https://t.co/mQA5rN0Hti The value above = the median percent change in NCPV (I calculated the percent change for all participants and then calculated the median of those values). The authors have given a value of 42.8. But they calculated this using the median change and the

May 8, 2025 · 13 likes · 1,128 followers View post →
Dustin Lambert
@CoachLamby · X

https://t.co/baHkBbyPX0 https://t.co/KtFO5bvi0Y

May 8, 2025 · 1 like · 59 followers View post →
North Woods Sara
@HohlyMohly · X

Here’s the link to the long awaited Letter to the Editor: https://t.co/zCLvV686Uy

May 8, 2025 · 1 like · 891 followers View post →
eleanorina
@_eleanorina · X

RT @realDaveFeldman: Needless to say it has felt like an eternity while we were working through the process with the journal -- but to be f…

May 8, 2025 · 1 share · 3,170 followers View post →
Christoffer Baustad Nilsen
@ChristofferBN · X

Excuse me? Some? 95 out of 100 of them... https://t.co/7RkYSignkT https://t.co/X0kAm6xwSP

May 8, 2025 · 19 likes · 585 followers View post →
Dave Feldman
@realDaveFeldman · X

Needless to say it has felt like an eternity while we were working through the process with the journal -- but to be fair to them, it was an eternity in Internet Time(tm) Here's the reply to LTE:https://t.co/zEpXo9SUdk And below is linked my new thread on our study/steps ahead https://t.co/LPMUkDQXIm

May 8, 2025 · 14 likes · 1 share · 84,363 followers View post →
Nick Norwitz MD PhD
@nicknorwitz · X

11/11) For an easy-read version of the thread, with hyperlinks and a bit more information, see: https://t.co/rqNlHe2WFw For our LTE response letter: https://t.co/Igb52P4f2M For the Open Access Table: https://t.co/8ThyubFPPw For the Podcast with Chris @VivaLongevity and Dave:

May 8, 2025 · 61 likes · 6 shares · 109,058 followers View post →