NEOADAURA results @JCO_ASCO after #ASCO25 presentation. In pts with resectable #EGFR NSCLC, neoadjuvant osimertinib x 9w led to MPR rate 25%, osi + chemo MPR 26%, placebo + chemo MPR 2%. EFS rates high but most pts received adjuvant osi. https://t.co/kS6HLYAByx
Neoadjuvant Osimertinib for Resectable -Mutated Non-Small Cell Lung Cancer.
Mentions
Extended reach
Total likes
Video views
Mentions per month
Jun 2025 – Sep 2025Where it's discussed
-
X / Twitter85 posts
-
News4 articles
-
YouTube2 videos
-
Facebook2 posts
-
Reddit2 posts
-
Blogs2 articles
AI synopsis
What people are saying
The discussions encompass highlights from the study, such as the comparative efficacy of neoadjuvant osimertinib versus chemotherapy in achieving higher major pathologic response rates, with statements like 'major pathologic response 25% compared with 2% for chemotherapy' demonstrating the transformative potential of the findings. The choice of language, such as 'significantly improves treatment outcomes,' contributes to a tone of optimism and urgency around the implications of this research for clinical practice.
The majority of discussions express a general support for the findings of the publication, showing slight agreement with the research outcomes.
Several posts reveal a strong curiosity about the efficacy of osimertinib, indicating that the topic is highly relevant to those engaged.
While many discussions reference the main findings, the level of deep analysis in the posts remains moderate and varied.
Participants perceive the publication as having significant influence on treatment approaches for lung cancer, noting improved outcomes.
Abstract in brief
- Neoadjuvant osimertinib, with or without chemotherapy, shows significant improvement in major pathologic response compared to placebo in patients with non-small cell lung cancer (NSCLC) before surgery.
- A phase III study involved 358 patients and found that those receiving osimertinib plus chemotherapy had a 26% major pathologic response rate, while those on osimertinib alone had a 25% response rate.
- The study also noted high event-free survival rates at 12 months and identified adverse events, but no new safety concerns emerged with the treatments.
Top posts
Most liked on X and BlueskyHot off the press from #ASCO25!
Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non–Small Cell Lung Cancer. Read full article. https://t.co/7WGW5FItmi
【NeoADAURA: Neoadjuvant Osimertinib for Resectable EGFR-Mutated NSCLC】
Neo-ADAURA trial presented at #ASCO25 and published at Journal of Clinical Oncology @OncoAlert Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non-Small-Cell Lung Cancer | Journal of Clinical Oncology https://t.co/f5lSPN4WgO
Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non-Small-Cell Lung Cancer | Journal of Clinical Oncology @OncoAlert #ASCO25 https://t.co/zpPWe7BoPK
All mentions
Neoadjuvant Osimertinib's Impact on EGFR-Mutated NSCLC Outcomes
In this episode, we discuss the JCO article on neoadjuvant osimertinib for resectable EGFR-mutated non-small cell lung cancer (NSCLC). The phase III study shows significant improvement in pathologic response rates and…
Neoadjuvant Osimertinib for Resectable NSCLC: Key Findings
This video discusses the significant improvement in major pathologic response with neoadjuvant osimertinib in patients with resectable EGFR-mutated non-small cell lung cancer. A phase III study of 358 patients reveals…
LUNG: in a study of stage II-IIIB EGFR mutant NSCLC, neoadjuvant EGFR inhibition (osimertinib) delivered major pathologic response 25% compared with 2% for chemotherapy. https://t.co/7krtaQNr3W
Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non–Small Cell Lung Cancer | Journal of Clinical Oncology https://t.co/zCdET7Dcy2
NACとしてのosime±chemo。Osi使用でMPR 25%ほど。EGFR TKIだけでは治せないんだなあと。 #Osler論文メモ https://t.co/TS4s2TVxJs
Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non-Small Cell Lung Cancer - PubMed https://t.co/LeKTe1RJPz
RT @JCO_ASCO: Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non–Small Cell Lung Cancer. Read full article. https://t.co/7WGW5FItmi
RT @JCO_ASCO: Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non–Small Cell Lung Cancer. Read full article. https://t.co/7WGW5FItmi
RT @JCO_ASCO: Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non–Small Cell Lung Cancer. Read full article. https://t.co/7WGW5FItmi
RT @JCO_ASCO: Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non–Small Cell Lung Cancer. Read full article. https://t.co/7WGW5FItmi
RT @JCO_ASCO: Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non–Small Cell Lung Cancer. Read full article. https://t.co/7WGW5FItmi
RT @JCO_ASCO: Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non–Small Cell Lung Cancer. Read full article. https://t.co/7WGW5FItmi
RT @JCO_ASCO: Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non–Small Cell Lung Cancer. Read full article. https://t.co/7WGW5FItmi
RT @JCO_ASCO: Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non–Small Cell Lung Cancer. Read full article. https://t.co/7WGW5FItmi
RT @JCO_ASCO: Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non–Small Cell Lung Cancer. Read full article. https://t.co/7WGW5FItmi
RT @JCO_ASCO: Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non–Small Cell Lung Cancer. Read full article. https://t.co/7WGW5FItmi
RT @JCO_ASCO: Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non–Small Cell Lung Cancer. Read full article. https://t.co/7WGW5FItmi
RT @JCO_ASCO: Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non–Small Cell Lung Cancer. Read full article. https://t.co/7WGW5FItmi
RT @JCO_ASCO: Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non–Small Cell Lung Cancer. Read full article. https://t.co/7WGW5FItmi
Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non–Small Cell Lung Cancer. Read full article. https://t.co/7WGW5FItmi
RT @OncLive: @Jani_Chinmay @ChaftJamie @SocietyofMSKCC Full article at : https://t.co/qYuNYOOYjV
Lo scopo del lavoro: "L'osimertinib in neoadiuvante migliora la prognosi dei pazienti con cancro al polmone non a piccole cellule (NSCLC) resecabile ed EGFR-mutato, come succede quando lo si usa in adiuvante?..". La risposta è SI! https://t.co/5JZoOnLmlb
RT @StephenVLiu: NEOADAURA results @JCO_ASCO after #ASCO25 presentation. In pts with resectable #EGFR NSCLC, neoadjuvant osimertinib x 9w l…
RT @StephenVLiu: NEOADAURA results @JCO_ASCO after #ASCO25 presentation. In pts with resectable #EGFR NSCLC, neoadjuvant osimertinib x 9w l…
#Paper | Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non-Small-Cell #LungCancer @ASCO @JCO_ASCO Access the entire article here
Osimertinib, with or without chemotherapy, significantly improves treatment outcomes for patients with resectable tumors compared to chemotherapy alone. by He J, Tsuboi M (...) Chaft JE et 24 al. in J Clin Oncol https://t.co/HSbybVKzzr #MedX #MedResearch
RT @StephenVLiu: NEOADAURA results @JCO_ASCO after #ASCO25 presentation. In pts with resectable #EGFR NSCLC, neoadjuvant osimertinib x 9w l…
RT @StephenVLiu: NEOADAURA results @JCO_ASCO after #ASCO25 presentation. In pts with resectable #EGFR NSCLC, neoadjuvant osimertinib x 9w l…
RT @StephenVLiu: NEOADAURA results @JCO_ASCO after #ASCO25 presentation. In pts with resectable #EGFR NSCLC, neoadjuvant osimertinib x 9w l…
RT @StephenVLiu: NEOADAURA results @JCO_ASCO after #ASCO25 presentation. In pts with resectable #EGFR NSCLC, neoadjuvant osimertinib x 9w l…
RT @StephenVLiu: NEOADAURA results @JCO_ASCO after #ASCO25 presentation. In pts with resectable #EGFR NSCLC, neoadjuvant osimertinib x 9w l…
RT @StephenVLiu: NEOADAURA results @JCO_ASCO after #ASCO25 presentation. In pts with resectable #EGFR NSCLC, neoadjuvant osimertinib x 9w l…
RT @StephenVLiu: NEOADAURA results @JCO_ASCO after #ASCO25 presentation. In pts with resectable #EGFR NSCLC, neoadjuvant osimertinib x 9w l…
RT @StephenVLiu: NEOADAURA results @JCO_ASCO after #ASCO25 presentation. In pts with resectable #EGFR NSCLC, neoadjuvant osimertinib x 9w l…
RT @StephenVLiu: NEOADAURA results @JCO_ASCO after #ASCO25 presentation. In pts with resectable #EGFR NSCLC, neoadjuvant osimertinib x 9w l…
RT @StephenVLiu: NEOADAURA results @JCO_ASCO after #ASCO25 presentation. In pts with resectable #EGFR NSCLC, neoadjuvant osimertinib x 9w l…
RT @StephenVLiu: NEOADAURA results @JCO_ASCO after #ASCO25 presentation. In pts with resectable #EGFR NSCLC, neoadjuvant osimertinib x 9w l…
RT @StephenVLiu: NEOADAURA results @JCO_ASCO after #ASCO25 presentation. In pts with resectable #EGFR NSCLC, neoadjuvant osimertinib x 9w l…
RT @StephenVLiu: NEOADAURA results @JCO_ASCO after #ASCO25 presentation. In pts with resectable #EGFR NSCLC, neoadjuvant osimertinib x 9w l…
RT @StephenVLiu: NEOADAURA results @JCO_ASCO after #ASCO25 presentation. In pts with resectable #EGFR NSCLC, neoadjuvant osimertinib x 9w l…
RT @StephenVLiu: NEOADAURA results @JCO_ASCO after #ASCO25 presentation. In pts with resectable #EGFR NSCLC, neoadjuvant osimertinib x 9w l…
RT @StephenVLiu: NEOADAURA results @JCO_ASCO after #ASCO25 presentation. In pts with resectable #EGFR NSCLC, neoadjuvant osimertinib x 9w l…
RT @StephenVLiu: NEOADAURA results @JCO_ASCO after #ASCO25 presentation. In pts with resectable #EGFR NSCLC, neoadjuvant osimertinib x 9w l…
RT @StephenVLiu: NEOADAURA results @JCO_ASCO after #ASCO25 presentation. In pts with resectable #EGFR NSCLC, neoadjuvant osimertinib x 9w l…
NEOADAURA results @JCO_ASCO after #ASCO25 presentation. In pts with resectable #EGFR NSCLC, neoadjuvant osimertinib x 9w led to MPR rate 25%, osi + chemo MPR 26%, placebo + chemo MPR 2%. EFS rates high but most pts received adjuvant osi. https://t.co/kS6HLYAByx
https://t.co/ivSMQPUxzZ
RT @JCO_ASCO: Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non-Small-Cell Lung Cancer. Read full article. https://t.co/CNMoEPLJoX…
Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non-Small-Cell Lung Cancer | Journal of Clinical Oncology https://t.co/WHNZOD0SCV
RT @JCO_ASCO: Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non-Small-Cell Lung Cancer. Read full article. https://t.co/CNMoEPLJoX…
Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non-Small-Cell Lung Cancer | Journal of Clinical Oncology https://t.co/Wins8g98wG
RT @JCO_ASCO: Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non-Small-Cell Lung Cancer. Read full article. https://t.co/CNMoEPLJoX…
RT @JCO_ASCO: Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non-Small-Cell Lung Cancer. Read full article. https://t.co/CNMoEPLJoX…
Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non-Small-Cell Lung Cancer. Read full article. https://t.co/CNMoEPLJoX #NSCLC
11/Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non-Small-Cell Lung Cancer @JCO_ASCO #ASCO25 @ASCO https://t.co/jMGUqfXjtQ
Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non-Small-Cell Lung Cancer https://t.co/4tg7XmSZLU #hvhebron #onco [Text complet]
RT @M_Torasawa: Hot off the press from #ASCO25!
RT @bmassutis: Neo-ADAURA trial presented at #ASCO25 and published at Journal of Clinical Oncology @OncoAlert Neoadjuvant Osimertinib for R…
RT @bmassutis: Neo-ADAURA trial presented at #ASCO25 and published at Journal of Clinical Oncology @OncoAlert Neoadjuvant Osimertinib for R…
‼️ #ASCO25 simultaneous publication by Chaft et al: Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non-Small-Cell Lung Cancer. Read the full article: https://t.co/I9MWGaTQDH #NSCLC #LungCancer #lcsm https://t.co/myUJ5rlBKd
RT @M_Torasawa: Hot off the press from #ASCO25!
RT @M_Torasawa: Hot off the press from #ASCO25!
RT @bmassutis: Neo-ADAURA trial presented at #ASCO25 and published at Journal of Clinical Oncology @OncoAlert Neoadjuvant Osimertinib for R…
RT @bmassutis: Neo-ADAURA trial presented at #ASCO25 and published at Journal of Clinical Oncology @OncoAlert Neoadjuvant Osimertinib for R…
RT @M_Torasawa: Hot off the press from #ASCO25!
RT @M_Torasawa: Hot off the press from #ASCO25!
RT @M_Torasawa: Hot off the press from #ASCO25!
Hot off the press from #ASCO25!
RT @bmassutis: Neo-ADAURA trial presented at #ASCO25 and published at Journal of Clinical Oncology @OncoAlert Neoadjuvant Osimertinib for R…
RT @bmassutis: Neo-ADAURA trial presented at #ASCO25 and published at Journal of Clinical Oncology @OncoAlert Neoadjuvant Osimertinib for R…
RT @bmassutis: Neo-ADAURA trial presented at #ASCO25 and published at Journal of Clinical Oncology @OncoAlert Neoadjuvant Osimertinib for R…
Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non-Small-Cell Lung Cancer | Journal of Clinical Oncology https://t.co/P8fXuDwYRM
Neo-ADAURA trial presented at #ASCO25 and published at Journal of Clinical Oncology @OncoAlert Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non-Small-Cell Lung Cancer | Journal of Clinical Oncology https://t.co/f5lSPN4WgO
RT @OncLive: @Jani_Chinmay @ChaftJamie @SocietyofMSKCC Full article at : https://t.co/qYuNYOOYjV
RT @M_Torasawa: 【NeoADAURA: Neoadjuvant Osimertinib for Resectable EGFR-Mutated NSCLC】
RT @Erman_Akkus: Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non-Small-Cell Lung Cancer | Journal of Clinical Oncology @OncoAlert…
https://t.co/RyUDbE3sv2
RT @Erman_Akkus: Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non-Small-Cell Lung Cancer | Journal of Clinical Oncology @OncoAlert…
RT @Erman_Akkus: Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non-Small-Cell Lung Cancer | Journal of Clinical Oncology @OncoAlert…
RT @Erman_Akkus: Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non-Small-Cell Lung Cancer | Journal of Clinical Oncology @OncoAlert…
RT @Erman_Akkus: Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non-Small-Cell Lung Cancer | Journal of Clinical Oncology @OncoAlert…
@Jani_Chinmay @ChaftJamie @SocietyofMSKCC Full article at : https://t.co/qYuNYOOYjV
Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non-Small-Cell Lung Cancer | Journal of Clinical Oncology @OncoAlert #ASCO25 https://t.co/zpPWe7BoPK
Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non-Small-Cell Lung Cancer https://t.co/QLMUZ5cyCE
RT @M_Torasawa: 【NeoADAURA: Neoadjuvant Osimertinib for Resectable EGFR-Mutated NSCLC】
【NeoADAURA: Neoadjuvant Osimertinib for Resectable EGFR-Mutated NSCLC】
Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non-Small-Cell Lung Cancer | @JCO_ASCO https://t.co/PtzVa1yowP