Stem Cell-Derived, Fully Differentiated Islets for Type 1 Diabetes.

Trevor W Reichman, James F Markmann, Jon Odorico, Piotr Witkowski, John J Fung, Martin Wijkstrom, Fouad Kandeel, Eelco J P de Koning, Anne L Peters, Chantal Mathieu, Leslie S Kean, Bote G Bruinsma, Chenkun Wang, Molly Mascia, Bastiano Sanna

September 2025 N Engl J Med

Synopsis of Social media discussions

The overall tone captures excitement about the therapy's promise, with posts citing specific trial results like 83% insulin independence and references to high-profile research publications. Words like 'cure,' 'transformative,' and 'hope' reflect both optimism and active engagement in exploring the potential impact of these scientific advances.

A
Agreement
 Moderate agreement

Most discussions highlight the promising results and potential of the stem cell therapy, indicating strong support for the research conclusions.

I
Interest
 High level of interest

The posts actively explore various aspects, including trial outcomes and future implications, demonstrating high curiosity about the developments.

E
Engagement
 High engagement

Many discussions reference specific studies, clinical trials, and expert opinions, showing in-depth involvement.

I
Impact
 High level of impact

The tone suggests that these advances could revolutionize diabetes treatment, implying a significant impact on medical practices and patient lives.

Social Mentions

YouTube

5 Videos

Bluesky

21 Posts

Facebook

5 Posts

Twitter

218 Posts

Blogs

15 Articles

News

173 Articles

Reddit

3 Posts

Metrics

Video Views

1,859,988

Total Likes

90,629

Extended Reach

5,031,731

Social Features

440

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

Stem Cell Therapy Shows Promise for Type 1 Diabetes Treatment

Stem Cell Therapy Shows Promise for Type 1 Diabetes Treatment

A stem cell-based infusion potentially cured 10 of 12 severe type 1 diabetes patients, with no need for insulin after one year. The study evaluates zimislecel, a stem cell-derived therapy, assessing safety and efficacy, including engraftment success and adverse effects.

Dr Ben Miles

July 6, 2025

1,767,896 views

Advances in Stem Cell Therapy for Type 1 Diabetes Treatment

Advances in Stem Cell Therapy for Type 1 Diabetes Treatment

The study evaluates the safety and effectiveness of zimislecel, a stem cell-derived therapy, in treating type 1 diabetes. Participants underwent infusions of either a half dose or full dose of zimislecel and received glucocorticoid-free immunosuppressive therapy.

Nunca vi 1 cientista

July 15, 2025

88,925 views

Advancements in Stem Cell Therapy for Type 1 Diabetes Treatment

Advancements in Stem Cell Therapy for Type 1 Diabetes Treatment

A clinical trial demonstrates that stem cell therapy can enable type 1 diabetes patients to produce their own insulin, reducing or eliminating daily injections. The therapy involves infusing cultured stem cell-derived pancreatic islet cells into the liver, promising a potential breakthrough in diabetes management.

Advancells: Stem Cell Research & Development

July 16, 2025

2,171 views

Stem Cell Therapy Achieves Remission in Severe Type 1 Diabetes Patients

Stem Cell Therapy Achieves Remission in Severe Type 1 Diabetes Patients

The VX880 study published in NEJM shows impressive results, with 83% of severe type 1 diabetes patients achieving insulin independence after a single infusion of stem cell-derived islets, highlighting a promising future for cellular therapies.

Investigación Clínica Global

June 23, 2025

816 views

Stem Cell-Based Fully Differentiated Islets for Type 1 Diabetes Treatment

Stem Cell-Based Fully Differentiated Islets for Type 1 Diabetes Treatment

This study evaluates the safety and effectiveness of zimislecel, a stem cell-derived therapy, in treating type 1 diabetes. Participants received infusions with immunosuppressive therapy; results showed successful engraftment but included some serious adverse effects.

علوم طبية وتكنولوجيا Medical Sciences & Technology

June 28, 2025

182 views

  • Zoey
    @Zoeynzyjo1122 (Twitter)

    RT @EricTopol: New @NEJM Pluripotent stem cells for Type 1 diabetes restored pancreatic islet cell function, improved glucose regulation, a…
    view full post

    November 27, 2025

    66

  • Asociación Puertorriqueña Energía Verde (APEV)
    @energiaverdepr (Twitter)

    https://t.co/3D12zNIQAy Ahora los científicos están aprendiendo a restaurar la fuente misma de la secreción de insulina, para devolver las partes que faltan.
    view full post

    November 24, 2025

  • Immortality
    @Immortality_IMT (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes is not in situ pancreas regeneration but cured type 1 diabetes in a small trial. https://t.co/IHJXFpiKiw
    view full post

    November 9, 2025

  • Hao Yin
    @HaoYin20 (Twitter)

    RT @HaoYin20: BTW, this paper is on @ResearchHub https://t.co/e40ABK567W Anyone interested in reviewing it, here are some relevant pubs…
    view full post

    November 6, 2025

    1

  • Hao Yin
    @HaoYin20 (Twitter)

    BTW, this paper is on @ResearchHub https://t.co/e40ABK567W Anyone interested in reviewing it, here are some relevant pubs 1⃣Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes @VertexPharma VX-880-101 trial @NEJM 2025 https://t.co/Z58svYuzTR 2⃣Human assembloid https://t.co/UBiLVZLUIF
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    November 6, 2025

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  • Alice lee
    @Alice5744jv (Twitter)

    RT @EricTopol: New @NEJM Pluripotent stem cells for Type 1 diabetes restored pancreatic islet cell function, improved glucose regulation, a…
    view full post

    November 4, 2025

    66

  • Sara
    @SMCADMAN (Twitter)

    RT @SMCADMAN: 3/ Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes https://t.co/vVVCqvGokK
    view full post

    October 28, 2025

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  • Sara
    @SMCADMAN (Twitter)

    RT @SMCADMAN: 3/ Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes https://t.co/vVVCqvGokK
    view full post

    October 19, 2025

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  • Sehaj
    @SehajFund (Twitter)

    @princetongb $VRTX has Zimislecel as well that I haven’t read too much on yet. Sounded promising on my initial skim “Stem Cell-Derived, Fully Differentiated Islets for Type 1 Diabetes” on pubmed
    view full post

    October 11, 2025

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  • Ahmed Faisal
    @Faisalnaifaru (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes https://t.co/59LMx8rn7N
    view full post

    October 6, 2025

  • America Lady
    @American_Lady04 (Twitter)

    RT @EricTopol: New @NEJM Pluripotent stem cells for Type 1 diabetes restored pancreatic islet cell function, improved glucose regulation, a…
    view full post

    September 29, 2025

    66

  • W.Alter_Egoh
    @TheKunta_Kinte (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/Pe3u9P9gzf
    view full post

    September 20, 2025

  • DeepManek9
    @Deepmanek99 (Twitter)

    RT @omlakhani: Newer Updates in Type 1 Diabetes Management References: 1. Reichman TW, Markmann JF, Odorico J, Witkowski P, Fung JJ, Wi…
    view full post

    September 18, 2025

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  • CivilisatioTransform
    @CapabilitYes (Twitter)

    RT @ParrishLiz: https://t.co/a8gd76WM2d
    view full post

    September 18, 2025

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  • Dr. Om Lakhani, MD, DNB (ENDO)
    @omlakhani (Twitter)

    Newer Updates in Type 1 Diabetes Management References: 1. Reichman TW, Markmann JF, Odorico J, Witkowski P, Fung JJ, Wijkstrom M, et al. Stem Cell--Derived, Fully Differentiated Islets for Type 1 Diabetes. N Engl J Med. 2025 Sep 4;393(9):858-68. DOI: 10.1056/NEJMoa2506549. 2
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    September 18, 2025

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  • BreakthroughMedicine&AdvancedResearchTools
    @JayChance12 (Twitter)

    RT @ParrishLiz: https://t.co/a8gd76WM2d
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    September 14, 2025

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  • STITCHES Medicine - the Best of Medical Research
    @STITCHESMed (Twitter)

    Stem cell therapy zimislecel restored islet function in 83% of type 1 diabetes patients, achieving insulin independence and stable glucose control. by Reichman TW, Markmann JF (...) Rickels MR et 17 al. in N Engl J Med https://t.co/Bd0IXaFic2 #MedX #MedResearch
    view full post

    September 13, 2025

  • Lynn Dickerson
    @LynnDic76525801 (Twitter)

    RT @CMichaelGibson: 10 of 12 #diabetes patients treated with stem cell–derived, fully differentiated Islets for Type 1 Diabetes remained fr…
    view full post

    September 10, 2025

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  • Longevity
    @LongevityTao (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/BeKf6gClGj
    view full post

    September 9, 2025

  • DGG
    @DGG7334 (Twitter)

    RT @Kottond: An incredible advance in regenerative medicine, reported in @NEJM this week: Stem Cell–Derived, Fully Differentiated Islets f…
    view full post

    September 8, 2025

    5

  • Liz Parrish MBA
    @ParrishLiz (Twitter)

    https://t.co/a8gd76WM2d
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    September 8, 2025

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  • Camille Nelson Kotton
    @KottonNelson (Twitter)

    RT @Kottond: An incredible advance in regenerative medicine, reported in @NEJM this week: Stem Cell–Derived, Fully Differentiated Islets f…
    view full post

    September 8, 2025

    5

  • Önder Yildirim
    @AlionderCPC (Twitter)

    RT @Kottond: An incredible advance in regenerative medicine, reported in @NEJM this week: Stem Cell–Derived, Fully Differentiated Islets f…
    view full post

    September 8, 2025

    5

  • Stich Share
    @stich_share (Twitter)

    RT @EricTopol: New @NEJM Pluripotent stem cells for Type 1 diabetes restored pancreatic islet cell function, improved glucose regulation, a…
    view full post

    September 8, 2025

    64

  • Alexander Tatara, MD PhD
    @AMTatara (Twitter)

    RT @Kottond: An incredible advance in regenerative medicine, reported in @NEJM this week: Stem Cell–Derived, Fully Differentiated Islets f…
    view full post

    September 8, 2025

    5

  • Rob Hynds
    @robhynds (Twitter)

    RT @Kottond: An incredible advance in regenerative medicine, reported in @NEJM this week: Stem Cell–Derived, Fully Differentiated Islets f…
    view full post

    September 8, 2025

    5

  • Darrell Kotton
    @kottond.bsky.social (Bluesky)

    An incredible advance in regenerative medicine, published this week: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | NEJM: www.nejm.org/doi/full/10....
    view full post

    September 7, 2025

    5

    1

  • Darrell Kotton
    @Kottond (Twitter)

    An incredible advance in regenerative medicine, reported in @NEJM this week: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | #helpisonthe way! https://t.co/QImh0qPf9A
    view full post

    September 7, 2025

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  • クシネ
    @hare_niji (Twitter)

    RT @EARL_med_tw:
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    September 6, 2025

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  • みいたろ糖尿病と心理学勉強中
    @mi_taro55 (Twitter)

    RT @EARL_med_tw:
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    September 6, 2025

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  • とまはぼちぼち
    @fusasippona1 (Twitter)

    RT @EARL_med_tw:
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    September 5, 2025

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  • Carsten Skarke
    @CarstenSkarke (Twitter)

    RT @UPENN_ITMAT: Allogeneic #StemCell -derived islet- #CellTherapy as a candidate to restore physiologic #IsletFunction https://t.co/qTci3R…
    view full post

    September 5, 2025

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  • C☻Chihiro
    @oki_13_love (Twitter)

    RT @EARL_med_tw:
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    September 5, 2025

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  • EARLの医学&AIノート
    @EARL_med_tw (Twitter)


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    September 5, 2025

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  • Constance
    @jconstance61 (Twitter)

    RT @NEJM: Zimislecel is an allogeneic stem cell–derived islet-cell therapy. The VX-880-101 FORWARD phase 1–2 study supports the hypothesis…
    view full post

    September 5, 2025

    5

  • 旅人 tabito
    @tabibito250 (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/JFObkh8HSV
    view full post

    September 5, 2025

  • Fadel Alrowaie
    @fadelrowaie (Twitter)

    RT @NEJM: Zimislecel is an allogeneic stem cell–derived islet-cell therapy. The VX-880-101 FORWARD phase 1–2 study supports the hypothesis…
    view full post

    September 5, 2025

    5

  • Alexander Bartelt
    @BarteltLab (Twitter)

    RT @NEJM: Zimislecel is an allogeneic stem cell–derived islet-cell therapy. The VX-880-101 FORWARD phase 1–2 study supports the hypothesis…
    view full post

    September 5, 2025

    5

  • raksin
    @RaksoMcRakso (Twitter)

    RT @NEJM: Zimislecel is an allogeneic stem cell–derived islet-cell therapy. The VX-880-101 FORWARD phase 1–2 study supports the hypothesis…
    view full post

    September 5, 2025

    5

  • Tomás Griffin
    @TomasPGriffin (Twitter)

    RT @NEJM: Zimislecel is an allogeneic stem cell–derived islet-cell therapy. The VX-880-101 FORWARD phase 1–2 study supports the hypothesis…
    view full post

    September 5, 2025

    5

  • NEJM
    @NEJM (Twitter)

    Zimislecel is an allogeneic stem cell–derived islet-cell therapy. The VX-880-101 FORWARD phase 1–2 study supports the hypothesis that zimislecel can restore physiologic islet function and thus treat persons with type 1 diabetes. Full study results: https://t.co/4WOqQUIv3S https://t.co/8SbiPo80vy
    view full post

    September 5, 2025

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  • KIN LOPEZ
    @KINWAHSIU (Twitter)

    RT @NEJM: New in the September 4, 2025, issue of NEJM: Maridebart Cafraglutide for the Treatment of Obesity (MariTide phase 2 trial) htt…
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    September 4, 2025

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  • Dr. Joshuan J. Barboza
    @joshuanbarbozam (Twitter)

    RT @NEJM: New in the September 4, 2025, issue of NEJM: Maridebart Cafraglutide for the Treatment of Obesity (MariTide phase 2 trial) htt…
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    September 4, 2025

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  • Wei-Guo Ma, MD
    @Dr_Ma_of_PUMC (Twitter)

    RT @NEJM: New in the September 4, 2025, issue of NEJM: Maridebart Cafraglutide for the Treatment of Obesity (MariTide phase 2 trial) htt…
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    September 4, 2025

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  • Sameer Ahmed
    @SameerA41115539 (Twitter)

    RT @NEJM: New in the September 4, 2025, issue of NEJM: Maridebart Cafraglutide for the Treatment of Obesity (MariTide phase 2 trial) htt…
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    September 4, 2025

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  • Martin Michaelis
    @MartMichaelis (Twitter)

    Hope for type I #diabetes patients. https://t.co/aFkwJezvNy
    view full post

    September 4, 2025

  • Lanqi Hua
    @LanqiHua (Twitter)

    RT @NEJM: New in the September 4, 2025, issue of NEJM: Maridebart Cafraglutide for the Treatment of Obesity (MariTide phase 2 trial) htt…
    view full post

    September 4, 2025

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  • Mark
    @headass_deadass (Twitter)

    RT @NEJM: New in the September 4, 2025, issue of NEJM: Maridebart Cafraglutide for the Treatment of Obesity (MariTide phase 2 trial) htt…
    view full post

    September 4, 2025

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  • Firas F Mussa
    @UnTBAD (Twitter)

    RT @NEJM: New in the September 4, 2025, issue of NEJM: Maridebart Cafraglutide for the Treatment of Obesity (MariTide phase 2 trial) htt…
    view full post

    September 4, 2025

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  • ITMAT
    @UPENN_ITMAT (Twitter)

    Allogeneic #StemCell -derived islet- #CellTherapy as a candidate to restore physiologic #IsletFunction https://t.co/qTci3RFbnV #DiabetesResearch #Diabetes #T1D #IsletBiology #TranslationalScience
    view full post

    September 4, 2025

    1

    1

  • Alex Gutiérrez-Dalmau
    @AlexGtrzD (Twitter)

    Great news and a highly anticipated article. Not a word about the immunosuppression received??? Just a mention in supplemental material (standard steroid-free IS, islet transplantation protocol by the Clinical Islet Transplantation Consortium). https://t.co/sPAbDsEgx4
    view full post

    September 4, 2025

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  • enigma4ever
    @watergatesummer (Twitter)

    RT @NEJM: New in the September 4, 2025, issue of NEJM: Maridebart Cafraglutide for the Treatment of Obesity (MariTide phase 2 trial) htt…
    view full post

    September 4, 2025

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  • Mar
    @marianaaggvv (Twitter)

    RT @NEJM: New in the September 4, 2025, issue of NEJM: Maridebart Cafraglutide for the Treatment of Obesity (MariTide phase 2 trial) htt…
    view full post

    September 4, 2025

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  • AADViK MEDiCS
    @aadvikmedics (Twitter)

    RT @NEJM: New in the September 4, 2025, issue of NEJM: Maridebart Cafraglutide for the Treatment of Obesity (MariTide phase 2 trial) htt…
    view full post

    September 4, 2025

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  • Josep Maria Cruzado
    @crz_garrit (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/yGkcuLcMSL
    view full post

    September 4, 2025

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  • Habib Cissé
    @Kissiland_man (Twitter)

    RT @NEJM: New in the September 4, 2025, issue of NEJM: Maridebart Cafraglutide for the Treatment of Obesity (MariTide phase 2 trial) htt…
    view full post

    September 4, 2025

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  • District 1 Research
    @District1ResNYC (Twitter)

    RT @NEJM: New in the September 4, 2025, issue of NEJM: Maridebart Cafraglutide for the Treatment of Obesity (MariTide phase 2 trial) htt…
    view full post

    September 4, 2025

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  • NEJM
    @NEJM (Twitter)

    New in the September 4, 2025, issue of NEJM: Maridebart Cafraglutide for the Treatment of Obesity (MariTide phase 2 trial) https://t.co/VBYUngj8GR Stem Cell–Derived Islets for Type 1 Diabetes (VX-880-101 FORWARD phase 1–2 study) https://t.co/4WOqQUIv3S Benzathine https://t.co/3uJ0UXj2Z1
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    September 4, 2025

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  • Sara
    @SMCADMAN (Twitter)

    RT @SMCADMAN: 3/ Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes https://t.co/vVVCqvGokK
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    August 21, 2025

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  • Serhat YILDIR
    @serhatyildir45 (Twitter)

    RT @DrGunerSonmez: İyi ki bilim var ❤️ İyi ki bilim insanları var ❤️ https://t.co/UivFYo9hYT https://t.co/cOo5ktoRMx
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    August 17, 2025

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  • 中華マフィア/デスさん/イツキ
    @InoZaikoDIESale (Twitter)

    RT @suzuki_takaya: ついにここまできた幹細胞治療の第3相試験。 胚性幹細胞（ES細胞）由来のベータ細胞の投与で1型糖尿病患者12人中10人が投与1年でインスリンフリーに。このES細胞は他人由来なので免疫抑制剤を併用しています。 https://t.co/gtF…
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    August 12, 2025

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  • Dr. Ole Olsen
    @oolsen50 (Twitter)

    @DGlaucomflecken A cure for diabetes is coming in the next few years from this technology https://t.co/n9fInckcZe
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    August 9, 2025

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  • AmericanRevival
    @American_Revi (Twitter)

    Scientists Cure First Type 1 Diabetes Patients https://t.co/dN6XZuGfJa via @YouTube
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    August 6, 2025

  • mastermagic
    @foxIVI (Twitter)

    https://t.co/MQDqTXKWG0
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    August 2, 2025

  • Eric Cadesky MD
    @drcadesky (Twitter)

    Stem cells hold promise as a cure for type 1 Diabetes https://t.co/7dXTFinWe8 https://t.co/i7WfHB7REa
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    July 30, 2025

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  • RBH
    @raymondbrucehe1 (Twitter)

    Scientists Cure First Type 1 Diabetes Patients https://t.co/Dk4P0yDso2 via @YouTube
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    July 29, 2025

  • みいたろ糖尿病と心理学勉強中
    @mi_taro55 (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/kTJyDK4MWa
    view full post

    July 28, 2025

  • 正しい医療知識を広める会／Medical Science Communication (MSC)
    @SHAcRoyJ32QmTuw (Twitter)


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    July 28, 2025

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  • Keeshlon
    @NancyMako (Twitter)

    https://t.co/eHuz4XSMWT
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    July 27, 2025

  • Warren Oliver Harris
    @WarrenHarr12310 (Twitter)

    Scientists Cure First Type 1 Diabetes Patients https://t.co/W8VAmoLKp7 via @YouTube
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    July 25, 2025

  • Carsten Skarke
    @CarstenSkarke (Twitter)

    RT @UPENN_ITMAT: Exploring the potential to restore physiologic islet function through fully differ¬entiated, allogeneic pluripotent stem c…
    view full post

    July 25, 2025

    1

  • BROTHER
    @Bir_Dost35 (Twitter)

    RT @DrGunerSonmez: İyi ki bilim var ❤️ İyi ki bilim insanları var ❤️ https://t.co/UivFYo9hYT https://t.co/cOo5ktoRMx
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    July 25, 2025

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  • Professor Booty PhD
    @ProfBootyPhD (Twitter)

    @Fearthecow93 @oncloud_e @JennaLynnMeowri jfc the US has multiple university research teams as well as huge companies working on this - it would be an instant Nobel Prize and a license to print money, it’s not being suppressed https://t.co/66pkYSpeE5
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    July 21, 2025

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  • Nikole
    @Victory0thePpl (Twitter)

    @DrNeilStone Type 1 diabetes may be curable: Stem Cell-Derived, Fully Differentiated Islets for Type 1 Diabetes - PubMed https://t.co/cyZnvBLviu
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    July 20, 2025

  • Marc Siegel MD
    @DrMarcSiegel (Twitter)

    RT @DrMarcSiegel: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine was great to intervi…
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    July 19, 2025

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  • Marc Siegel MD
    @DrMarcSiegel (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine was great to interview lead author Trevor Reichman MD on ⁦@NYUDocs⁩ ⁦@nyulangone⁩ at 2 PM yesterday on this amazing transplant https://t.co/5E0iKhGXhz
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    July 19, 2025

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  • Dr. Take_it_Easy
    @takeiteasy1982 (Twitter)


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    July 19, 2025

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  • Manos Giorgakis
    @ManosGiorgakis (Twitter)

    Stem Cell–Derived, Fully Differentiated #Islets for #T1DM @NEJM https://t.co/5vX0b9hYSi
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    July 18, 2025

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  • Wulan, Aprillia.
    @aprilliawwww (Twitter)

    RT @JeffreyRMillman: Big #T1D news! Vertex has published their phase 1–2 trial of stem cell-derived islets (VX880, now called zimislecel).…
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    July 18, 2025

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  • The Real RCT
    @TheRealRCT (Twitter)

    Stem-cell–derived islets may become a scalable cure for T1D. Still early days—but if these results hold in Phase 3, this will be a landmark in regenerative medicine. Not managing diabetes—ending it.
    view full post

    July 17, 2025

  • Project Blue November
    @PBlueNovember (Twitter)

    RT @JeffreyRMillman: Big #T1D news! Vertex has published their phase 1–2 trial of stem cell-derived islets (VX880, now called zimislecel).…
    view full post

    July 17, 2025

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  • ♡Jinx♡
    @XxXx_Jinx_xXxX (Twitter)

    https://t.co/5FSubKx9fR
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    July 15, 2025

  • Lauren
    @oglauren.bsky.social (Bluesky)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine They "conducted a phase 1–2 study of zimislecel in persons with type 1 diabetes." www.nejm.org/doi/full/10....
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    July 15, 2025

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  • VirusSucks.com
    @virussucks.com (Bluesky)

    Type 1 diabetes is often the result of a viral infection. Treatments are on the horizon. Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine www.nejm.org/doi/full/10....
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    July 14, 2025

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  • Gahro
    @GAHRO7 (Twitter)

    Here's the kind of thing that makes me love science and technology. https://t.co/J7esc9jLCa
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    July 14, 2025

  • Elias Tzelepis
    @Tze_Elias (Twitter)

    Allogenic stem cell–derived islet-cell therapy for type 1 diabetes #T1D #diabetology #endocrinology https://t.co/ySB2BL9Ged
    view full post

    July 13, 2025

  • imquang
    @imquang (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/EoU0zywCcT
    view full post

    July 13, 2025

  • First Officer
    @Erst_Officer (Twitter)

    @hobbs_joe34741 @DrNeilStone It is not officially reversible, yet. But until very recently, it was really not reversible. https://t.co/Z4ft2ZRfKz
    view full post

    July 11, 2025

    6

  • First Officer
    @Erst_Officer (Twitter)

    @DrNeilStone Not yet... (But through no fault of CHD.) https://t.co/Z4ft2ZRfKz
    view full post

    July 11, 2025

    1

  • Douglas Solomon
    @pither1952 (Twitter)

    https://t.co/EWlEjBZvHz
    view full post

    July 11, 2025

  • Alper Tunga Özdemir
    @atorbo (Twitter)

    RT @_jdevos_:
    view full post

    July 11, 2025

    4

  • Norio Nakatsuji
    @norionakatsuji (Twitter)

    RT @_jdevos_:
    view full post

    July 10, 2025

    4

  • Vladislav Sergeev
    @DrVladSergeev (Twitter)

    RT @_jdevos_:
    view full post

    July 10, 2025

    4

  • DrOlivierBoyer
    @DrOlivierBoyer (Twitter)

    RT @_jdevos_:
    view full post

    July 10, 2025

    4

  • عمار الخميسي . amar alkhamesi
    @amar_uk1 (Twitter)

    الخلايا الجذعية /داء السكري من النوع الأول. العلاج الجديد لهذا المرض. https://t.co/3dkHLkaJlk الخلايا الجذعية Pluripotent stem cells المحفزة المتعددة القدرات لمرض السكري من النوع الأول استعادت وظيفة خلايا البنكرياس الجزيرية وحسّنت تنظيم الجلوكوز glucose وقللت الحاجة إلى
    view full post

    July 10, 2025

    2

  • John De Vos
    @_jdevos_ (Twitter)


    view full post

    July 10, 2025

    4

    4

  • SPORTS EXTRA
    @tem_thierry (Twitter)

    RT @KiaNeu6: This singe injection diabetes treatment will free people from insulin injections https://t.co/4joBO0JKNV
    view full post

    July 8, 2025

    1

  • Prof. Anna Brown
    @KiaNeu6 (Twitter)

    This singe injection diabetes treatment will free people from insulin injections https://t.co/4joBO0JKNV
    view full post

    July 8, 2025

    3

    1

  • Eleonora Scorletti MD PhD
    @EScorletti (Twitter)


    view full post

    July 8, 2025

    1

  • HealthyBuilds
    @JamesSw70043542 (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes https://t.co/qkb4pMzSCl?
    view full post

    July 8, 2025

  • HealthyBuilds
    @HealthyBuilds (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes https://t.co/GoBNLJlTYb?
    view full post

    July 8, 2025

  • Donna D.
    @FreeSoverign_D (Twitter)

    Scientists Cure First Type 1 Diabetes Patients https://t.co/JKhTkXUWIp via @YouTube
    view full post

    July 8, 2025

  • Cynthia Solomon
    @CynthiaSol66248 (Twitter)

    https://t.co/BCIrAJUriM
    view full post

    July 7, 2025

  • PennSurgery
    @pennsurgery (Twitter)

    RT @PennMedCSO: A new study out in @NEJM supports the hypothesis that zimislecel can restore physiologic islet function in persons with typ…
    view full post

    July 7, 2025

    2

  • Emory Global Diabetes Research Center
    @egdrc (Twitter)


    view full post

    July 7, 2025

    1

  • Samuel Lewis
    @saminnomedai (Twitter)

    RT @drbennisahmed: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes The results of this small, short-term study involvin…
    view full post

    July 7, 2025

    5

  • AngryPhDstudent❗️❗️❗️
    @ONNESHA092 (Twitter)

    RT @drbennisahmed: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes The results of this small, short-term study involvin…
    view full post

    July 7, 2025

    5

  • Rajani Desai
    @bikecancermd (Twitter)

    RT @drbennisahmed: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes The results of this small, short-term study involvin…
    view full post

    July 7, 2025

    5

  • Tom Varghese Jr. MD, MS, MBA, FACS, MAMSE
    @TomVargheseJr (Twitter)

    RT @PennMedCSO: A new study out in @NEJM supports the hypothesis that zimislecel can restore physiologic islet function in persons with typ…
    view full post

    July 7, 2025

    2

  • andres
    @palacioendocrin (Twitter)

    RT @drbennisahmed: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes The results of this small, short-term study involvin…
    view full post

    July 7, 2025

    5

  • Penn Medicine CSO
    @PennMedCSO (Twitter)

    A new study out in @NEJM supports the hypothesis that zimislecel can restore physiologic islet function in persons with type 1 diabetes ft. Michael Rickels (@PennIDOM/ @PennEndocrine) & James Markmann (@PennSurgery) https://t.co/UCaFaGv694 https://t.co/Qf3Ccw97IU
    view full post

    July 7, 2025

    8

    2

  • Jesus Antonio Villegas Jr
    @v_man58 (Twitter)

    https://t.co/LuUEHBKHbB
    view full post

    July 7, 2025

  • Mohammad Aleidi
    @aleidimed (Twitter)

    RT @drbennisahmed: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes The results of this small, short-term study involvin…
    view full post

    July 7, 2025

    5

  • Ahmed Bennis MD
    @drbennisahmed (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes The results of this small, short-term study involving persons with type 1 diabetes support the hypothesis that zimislecel can restore physiologic islet function, warranting further clinical investigation https://t.co/Vl3ufTIOOI
    view full post

    July 7, 2025

    19

    5

  • Warren Oliver Harris
    @WarrenHarr12310 (Twitter)

    Scientists Cure First Type 1 Diabetes Patients https://t.co/MSeJKM5pPd via @YouTube
    view full post

    July 7, 2025

  • Famke Bojangles
    @FAMKEBOJANGLES (Twitter)

    https://t.co/HOk9NQwACP
    view full post

    July 6, 2025

  • Joe Bard
    @JoeBard53 (Twitter)


    view full post

    July 6, 2025

  • MichaelrHallen
    @michael407931 (Twitter)

    Scientists Cure First Type 1 Diabetes Patients https://t.co/65E63KUqQS via @YouTube
    view full post

    July 6, 2025

  • Manny Angel
    @SirMannyAngel (Twitter)

    Scientists Cure Type 1 Diabetes in First Patients https://t.co/42jircPz7D
    view full post

    July 6, 2025

    1

  • Primastcar
    @primastcar (Twitter)

    ▶️ Zimislecel ( terapia alogénica de islotes derivados de células madre ) ✅ Estudio de fase 1-2 ▶️ zimislecel puede restaurar la función fisiológica de los islotes páncreas
    view full post

    July 5, 2025


  • @abewust.bsky.social (Bluesky)

    Warning: the following article contains Scientific Facts & hopeful news Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabeteshttps://www.nejm.org/doi/full/10.1056/NEJMoa2506549
    view full post

    July 5, 2025

    1

  • Bob Baumann
    @AltePute (Twitter)

    RT @DrSamuelBHume: 4. Stem cell-derived islets for type 1 diabetes https://t.co/8ltiTPFTQV https://t.co/CKjOebAFiv
    view full post

    July 4, 2025

    4

  • じん
    @nijuoti (Twitter)

    RT @DrSamuelBHume: 4. Stem cell-derived islets for type 1 diabetes https://t.co/8ltiTPFTQV https://t.co/CKjOebAFiv
    view full post

    July 3, 2025

    4

  • Lynne Irwin
    @LLynneIrwin (Twitter)

    RT @CMichaelGibson: 10 of 12 #diabetes patients treated with stem cell–derived, fully differentiated Islets for Type 1 Diabetes remained fr…
    view full post

    July 3, 2025

    9

  • Dr. Gennadi Glinsky, MD, Ph.D.
    @gglinskii (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/eJB2vnHOfT
    view full post

    July 3, 2025

  • Dr. Gennadi Glinsky, MD, Ph.D.
    @gglinskii (Twitter)

    RT @DrSamuelBHume: 4. Stem cell-derived islets for type 1 diabetes https://t.co/8ltiTPFTQV https://t.co/CKjOebAFiv
    view full post

    July 3, 2025

    4

  • Samuel Hume
    @DrSamuelBHume (Twitter)

    4. Stem cell-derived islets for type 1 diabetes https://t.co/8ltiTPFTQV https://t.co/CKjOebAFiv
    view full post

    July 3, 2025

    38

    4

  • ForensicPsyMD
    @ForensicPsyMD (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/uaNA0UjORs
    view full post

    July 3, 2025

  • Professor Booty PhD
    @ProfBootyPhD (Twitter)

    @stgoldst @BiotechMongoose Stem cell transplants did so well in a type-1 diabetes trial that the company had to release the results early. https://t.co/tjVYX8vQGM
    view full post

    July 3, 2025

    2

  • Sunil V. Rao
    @SVRaoMD (Twitter)

    RT @CMichaelGibson: 10 of 12 #diabetes patients treated with stem cell–derived, fully differentiated Islets for Type 1 Diabetes remained fr…
    view full post

    July 3, 2025

    9

  • IWASHIMA Satoru岩島覚.MD, PhD.ﾔｰ
    @SIwa23288585 (Twitter)

    RT @CMichaelGibson: 10 of 12 #diabetes patients treated with stem cell–derived, fully differentiated Islets for Type 1 Diabetes remained fr…
    view full post

    July 3, 2025

    9

  • AЛEKCAНДAР KOЛAРИЋ
    @ALEARIANKO (Twitter)

    RT @CMichaelGibson: 10 of 12 #diabetes patients treated with stem cell–derived, fully differentiated Islets for Type 1 Diabetes remained fr…
    view full post

    July 3, 2025

    9

  • Sophia Kramer
    @HealthAI_Soph (Twitter)

    RT @CMichaelGibson: 10 of 12 #diabetes patients treated with stem cell–derived, fully differentiated Islets for Type 1 Diabetes remained fr…
    view full post

    July 2, 2025

    9

  • Pooja S
    @drpooja0916 (Twitter)

    RT @CMichaelGibson: 10 of 12 #diabetes patients treated with stem cell–derived, fully differentiated Islets for Type 1 Diabetes remained fr…
    view full post

    July 2, 2025

    9

  • Samuel Lewis
    @saminnomedai (Twitter)

    RT @CMichaelGibson: 10 of 12 #diabetes patients treated with stem cell–derived, fully differentiated Islets for Type 1 Diabetes remained fr…
    view full post

    July 2, 2025

    9

  • C. Michael Gibson MD
    @CMichaelGibson (Twitter)

    10 of 12 #diabetes patients treated with stem cell–derived, fully differentiated Islets for Type 1 Diabetes remained free of insulin use at one yr. 3 cases of neutropenia. https://t.co/652dtVwUGF
    view full post

    July 2, 2025

    22

    9

  • Kelvin R.
    @Kelvin_ramlo (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/jjZ1x0FEZM
    view full post

    July 2, 2025

  • Welcome to Future
    @WelcomeFuture_0 (Twitter)

    A woman with type 1 diabetes is now insulin-free after just a single stem cell implant. More: https://t.co/1b1gN3S7ZN #BREAKING #diabetes #InsulinResistance https://t.co/oRg7z0uspa
    view full post

    July 1, 2025

  • Horacio
    @hzavalacoca (Twitter)

    Islotes totalmente diferenciados derivados de células madre para la diabetes tipo 1 | New England Journal of Medicine https://t.co/gjfwGeEpCb
    view full post

    July 1, 2025

  • Horacio
    @hzavalacoca (Twitter)

    Islotes totalmente diferenciados derivados de células madre para la diabetes tipo 1 | New England Journal of Medicine https://t.co/gjfwGeEXrJ
    view full post

    July 1, 2025

  • Wachel J
    @JulienWachel (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/l7pC5doTWE
    view full post

    July 1, 2025

  • Drsoberon
    @Drsoberon1 (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/59f8zm6o0b Un poco de ciencia sobre células madre y tratamiento de Diabetes Mellitus tipo 1
    view full post

    June 30, 2025

    1

  • Javierpa95
    @javi95lol (Twitter)

    RT @ramosmd: ¿La cura de la #diabetes tipo 1? Zimislecel (islotes derivados de células madre) restauro la función de c. beta, elimino even…
    view full post

    June 30, 2025

    3

  • JoseM Garcia Almeida
    @jgarciaalmeida (Twitter)

    RT @ramosmd: ¿La cura de la #diabetes tipo 1? Zimislecel (islotes derivados de células madre) restauro la función de c. beta, elimino even…
    view full post

    June 30, 2025

    3

  • Dr Richard Palmquist
    @DrRPalmquist (Twitter)

    Stem Cell-Derived, Fully Differentiated Islets for Type 1 Diabetes Trevor W Reichman et al. N Engl J Med. 2025. https://t.co/ZUbQ0Cmdpb
    view full post

    June 29, 2025

  • Scott Amyx
    @ScottSAmyx (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes https://t.co/ZdPj5LAZ7Z
    view full post

    June 27, 2025

  • Scott Amyx
    @scottamyx.bsky.social (Bluesky)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes www.nejm.org/doi/full/10....
    view full post

    June 27, 2025

  • Serafin Murillo
    @serafinmurillo (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/YIMsxN7S2p
    view full post

    June 27, 2025

    4

  • Maria Robles
    @RBioceutics (Twitter)

    Vertex just cured 10/12 type 1 diabetics with stem cells #stemcells #t1d https://t.co/wKImCbjrbY
    view full post

    June 27, 2025

    1

  • Katherine Kokilashvili
    @kekaterine (Twitter)

    Stem Cell-Derived, Fully Differentiated Islets for Type 1 Diabetes - PubMed https://t.co/x3lp3AUxNm
    view full post

    June 27, 2025

  • гріцко
    @5RBzNB6n9iAmiDC (Twitter)

    RT @since1795: @KirillPol2 https://t.co/n2zCFHG46j
    view full post

    June 26, 2025

    1

  • Outis Yesod d'Atreu
    @kemzans (Twitter)

    RT @sakrustots: https://t.co/pamVq08pDC
    view full post

    June 26, 2025

    1

  • lettre d'inconnu
    @Lettreconforme (Twitter)

    https://t.co/SEidXOOGgL
    view full post

    June 26, 2025

  • Sara
    @SMCADMAN (Twitter)

    RT @SMCADMAN: 3/ Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes https://t.co/vVVCqvGokK
    view full post

    June 26, 2025

    4

  • Ryn Miake-Lye, PhD
    @sciencedriven.bsky.social (Bluesky)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine www.nejm.org/doi/full/10....
    view full post

    June 26, 2025

  • Ryn Miake-Lye, PhD
    @sciencedriven (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/DJJC19jY25
    view full post

    June 26, 2025

  • Research Bites
    @Research_Bites (Twitter)

    A small study suggests that zimislecel, an experimental therapy for type 1 diabetes, may restore islet cell function, allowing some participants to remain insulin independent. However, safety concerns need further investigation. - Read more: https://t.co/DuoC5649h4
    view full post

    June 26, 2025

    2

  • Бывший CTAPЛИHK , подпишись , Коты & Crypto
    @since1795 (Twitter)

    @KirillPol2 https://t.co/n2zCFHG46j
    view full post

    June 26, 2025

    9

    1

  • Ezzahidi Lalla soumia
    @EzzahidiS53933 (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/60dr5kC8eD
    view full post

    June 26, 2025

  • Krzysztof Pawinski
    @kpawinski (Twitter)

    To byłaby duża sprawa. Jeśli się przeskakuje. Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/hfOQIMwOFV
    view full post

    June 26, 2025

    2

  • Epilepsijas gaismiņa
    @sakrustots (Twitter)

    https://t.co/pamVq08pDC
    view full post

    June 26, 2025

    4

    1

  • Manny King
    @Mrmandeep_ (Twitter)

    This stem cell-based therapy offers a potentially transformative approach to restoring insulin production and reducing dependence on daily injections. https://t.co/NX5xH3BSJw
    view full post

    June 25, 2025

  • Prof Danny Altmann
    @daltmann.bsky.social (Bluesky)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine www.nejm.org/doi/full/10.... 83% had insulin independence and were not using exogenous insulin at day 365
    view full post

    June 25, 2025

    17

    11

  • Professor Dhananjaya Sharma
    @Dhananjayasha19 (Twitter)

    "Stem-cell treatment cures diabetes" No longer science fiction!
    view full post

    June 25, 2025

    1

  • Lucia Ruggiero EALR
    @luciaruggiero (Twitter)

    RT @GlobalPHObserv: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/bUnsD…
    view full post

    June 25, 2025

    4

  • Johann Fischer
    @greenai_wizard (Twitter)

    RT @GlobalPHObserv: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/bUnsD…
    view full post

    June 25, 2025

    4

  • Culture of Health Eq
    @CofHEQ (Twitter)

    RT @GlobalPHObserv: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/bUnsD…
    view full post

    June 25, 2025

    4

  • Rosa Sánchez
    @bilbao_health (Twitter)

    RT @GlobalPHObserv: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/bUnsD…
    view full post

    June 25, 2025

    4

  • Global Health Observ
    @GlobalPHObserv (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/bUnsDkIP2u
    view full post

    June 25, 2025

    4

    4

  • Shadira
    @MsMonsanto (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/DLXgFdxoLk
    view full post

    June 25, 2025

  • Rahman LAB
    @rahmanLAB2023 (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes https://t.co/tY9mTnxA2B
    view full post

    June 24, 2025

  • Pancreatic Cell News
    @PancreaticCell (Twitter)

    Collaborators, including Dr. Trevor Reichman from @UHN, show that zimislecel, an allogeneic stem cell–derived islet-cell therapy, can restore physiologic #islet function.
    view full post

    June 24, 2025

    1

  • PillowTalk W/ LauLei
    @PillowTalkLau (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/zvC9m3ITUr
    view full post

    June 24, 2025

  • Norio Nakatsuji
    @norionakatsuji (Twitter)

    RT @AusStemCell: ‘New Treatment May Cure Severe Type 1 Diabetes, Study Finds’ – results of a small, two-phase clinical trial of stem cell t…
    view full post

    June 24, 2025

    4

  • ITMAT
    @UPENN_ITMAT (Twitter)

    Exploring the potential to restore physiologic islet function through fully differ¬entiated, allogeneic pluripotent stem cell–derived islet-cell therapy for #Type1Diabetes https://t.co/qTci3RFJdt #StemCell #CellTherapy #TranslationalScience
    view full post

    June 24, 2025

    1

    1

  • Life Science Journal Content
    @lsn_jc (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes #science #publication #research #journal https://t.co/IClMl00cHx
    view full post

    June 24, 2025

  • Stem Cells Australia
    @StemCellsAus (Twitter)

    RT @AusStemCell: ‘New Treatment May Cure Severe Type 1 Diabetes, Study Finds’ – results of a small, two-phase clinical trial of stem cell t…
    view full post

    June 24, 2025

    4

  • Sara
    @SMCADMAN (Twitter)

    3/ Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes https://t.co/vVVCqvGokK
    view full post

    June 24, 2025

    2

    4

  • shaima_asadallah
    @shayom31 (Twitter)

    RT @AusStemCell: ‘New Treatment May Cure Severe Type 1 Diabetes, Study Finds’ – results of a small, two-phase clinical trial of stem cell t…
    view full post

    June 24, 2025

    4

  • James
    @Jamesmetrics (Twitter)

    RT @AusStemCell: ‘New Treatment May Cure Severe Type 1 Diabetes, Study Finds’ – results of a small, two-phase clinical trial of stem cell t…
    view full post

    June 24, 2025

    4

  • Stem Cell Foundation
    @AusStemCell (Twitter)

    ‘New Treatment May Cure Severe Type 1 Diabetes, Study Finds’ – results of a small, two-phase clinical trial of stem cell therapy developed by Boston-based @VertexPharma [Paper - https://t.co/DbGXbrddn6]: https://t.co/jzE8IS8Pmu @UofT
    view full post

    June 24, 2025

    3

    4

  • Jessica D
    @HealthTechJess (Twitter)

    RT @GlobalPHObserv: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/bUnsD…
    view full post

    June 23, 2025

    3

  • Bowen Wang
    @NU_JEANSS (Twitter)

    RT @NEJM: Original Article: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes (VX-880-101 FORWARD phase 1–2 study) https:/…
    view full post

    June 23, 2025

    33

  • tom hebert
    @tominwindsor (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/AkFEDc2DTf
    view full post

    June 23, 2025

    1

  • tom hebert
    @tominwindsor (Twitter)

    @RedKingRuairi1 Possible new treatment to cure Type 1 Diabetes.Great News.
    view full post

    June 23, 2025

    1

  • Culture of Health Eq
    @CofHEQ (Twitter)

    RT @GlobalPHObserv: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/bUnsD…
    view full post

    June 23, 2025

    3

  • Lucia Ruggiero EALR
    @luciaruggiero (Twitter)

    RT @GlobalPHObserv: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/bUnsD…
    view full post

    June 23, 2025

    3

  • Eve Beavers-Fain BSN MPH
    @espacetimeNOT (Twitter)

    RT @ESodicoffMD:
    view full post

    June 23, 2025

    1

  • Jose Torres
    @jtorresales (Twitter)

    "¿Un antes y un después en la #diabetes tipo1? #clinicaltrials #clinicalresearch #Zimislecel https://t.co/huWJFEXEUO via @YouTube
    view full post

    June 23, 2025

  • Vince Beltran, Ph.D.
    @levin_beltran (Twitter)

    RT @NEJM: Original Article: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes (VX-880-101 FORWARD phase 1–2 study) https:/…
    view full post

    June 23, 2025

    33

  • Global Health Observ
    @GlobalPHObserv (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/bUnsDkIP2u
    view full post

    June 23, 2025

    5

    3

  • Agathokakological
    @aaish_muhammad (Twitter)

    RT @drbennisahmed: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes The results of this small, short-term study involvin…
    view full post

    June 23, 2025

    5

  • Jishnu Venugopal
    @jishvenugopal (Twitter)

    RT @anishmohammed: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/ZdivKW…
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    June 23, 2025

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  • Anish Mohammed
    @anishmohammed (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/ZdivKWW1c8 < looks promising for Type 1 patients
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    June 23, 2025

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  • Abstream
    @abstreamme (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes #science #publication #research #publications https://t.co/TenfhOtuzq
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    June 23, 2025

  • Lily Huang
    @healthhikes (Twitter)

    RT @drbennisahmed: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes The results of this small, short-term study involvin…
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    June 23, 2025

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  • Dr Celestino Gutiérrez González MD
    @CelestinoGutirr (Twitter)

    RT @drbennisahmed: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes The results of this small, short-term study involvin…
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    June 23, 2025

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  • Julia Evans
    @julicaretech (Twitter)

    RT @drbennisahmed: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes The results of this small, short-term study involvin…
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    June 23, 2025

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  • Mohammad Aleidi
    @aleidimed (Twitter)

    RT @drbennisahmed: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes The results of this small, short-term study involvin…
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    June 23, 2025

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  • alberto aguirre de c
    @aaguirredc (Twitter)

    Avance esperanzador. Diez pacientes con diabetes tipo 1 severa no necesitan inyectarse insulina un año después de una sola infusión de células madre (hilo) Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/SFbNlw7LwI
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    June 23, 2025

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  • Ahmed Bennis MD
    @drbennisahmed (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes The results of this small, short-term study involving persons with type 1 diabetes support the hypothesis that zimislecel can restore physiologic islet function https://t.co/0adwU0meja https://t.co/BEmRF0Vi4i
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    June 23, 2025

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  • Hacker News 50
    @betterhn50.e-work.xyz (Bluesky)

    10 out of 12 people cured in Type 1 Diabetes Study https://www.nejm.org/doi/full/10.1056/NEJMoa2506549 (https://news.ycombinator.com/item?id=44351341)
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    June 22, 2025

  • Daiki Soma
    @daikisoma_uf (Twitter)

    RT @NEJM: Original Article: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes (VX-880-101 FORWARD phase 1–2 study) https:/…
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    June 22, 2025

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  • Daphne
    @FreeDaphne12 (Twitter)

    RT @NEJM: Original Article: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes (VX-880-101 FORWARD phase 1–2 study) https:/…
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    June 22, 2025

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  • Manos Giorgakis
    @ManosGiorgakis (Twitter)

    RT @NEJM: Original Article: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes (VX-880-101 FORWARD phase 1–2 study) https:/…
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    June 22, 2025

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  • Hacker News 20
    @betterhn20.e-work.xyz (Bluesky)

    10 out of 12 people cured in Type 1 Diabetes Study https://www.nejm.org/doi/full/10.1056/NEJMoa2506549 (https://news.ycombinator.com/item?id=44351341)
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    June 22, 2025

  • HackerNews Compilator
    @hnbot.gsuscs.xyz (Bluesky)

    10 out of 12 people cured in Type 1 Diabetes Study https://www.nejm.org/doi/full/10.1056/NEJMoa2506549
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    June 22, 2025

  • (((JReuben1)))
    @jreuben1 (Twitter)

    10 out of 12 people cured in Type 1 Diabetes Study https://t.co/hw5YMk0v85 Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes
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    June 22, 2025

  • HN
    @hnws.bsky.social (Bluesky)

    10 out of 12 people cured in Type 1 Diabetes Study L: https://www.nejm.org/doi/full/10.1056/NEJMoa2506549 C: https://news.ycombinator.com/item?id=44351341 posted on 2025.06.22 at 20:17:24 (c=2, p=5)
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    June 22, 2025

  • Bioinvestor24
    @bioinvestor24 (Twitter)

    RT @NEJM: Original Article: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes (VX-880-101 FORWARD phase 1–2 study) https:/…
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  • Eric Sodicoff
    @ESodicoffMD (Twitter)


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  • INTERNAL MEDICINE
    @medicinterna (Twitter)

    RT @giorg_kyriakos:
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    June 22, 2025

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  • Shima Aziz
    @AzizShima1990 (Twitter)

    RT @NEJM: Original Article: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes (VX-880-101 FORWARD phase 1–2 study) https:/…
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  • @beornblack.bsky.social (Bluesky)

    www.nejm.org/doi/full/10.... Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes!
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    June 22, 2025

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  • 旅人 tabito
    @tabibito250 (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/JFObkh8HSV
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    June 22, 2025

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  • ぜのぱす（初代_凍結から快復）
    @Xenopus007 (Twitter)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine https://t.co/EEW0g1OOsh
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    June 22, 2025

  • Shinichiro Ogawa
    @ogshinichiro (Twitter)

    RT @bradwouters: Exciting new clinical progress in stem cell derived therapies ⁦@UHN⁩ @UHNTransplant⁩ Stem Cell–Derived, Fully Differenti…
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    June 22, 2025

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  • Adrian Morales
    @adcomics4life (Twitter)

    RT @NEJM: Original Article: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes (VX-880-101 FORWARD phase 1–2 study) https:/…
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    June 22, 2025

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  • Carlos Palacio
    @CAPE1223 (Twitter)

    RT @NEJM: Original Article: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes (VX-880-101 FORWARD phase 1–2 study) https:/…
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    June 22, 2025

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  • Alejandro De Los Angeles, DPhil, MPH
    @delosangeles520 (Twitter)

    RT @NEJM: Original Article: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes (VX-880-101 FORWARD phase 1–2 study) https:/…
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    June 22, 2025

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  • BirmingSteve
    @BirmingSteve (Twitter)

    RT @NEJM: Original Article: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes (VX-880-101 FORWARD phase 1–2 study) https:/…
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    June 22, 2025

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  • Dr. OncoGuru
    @CellFightMD (Twitter)

    RT @NEJM: Original Article: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes (VX-880-101 FORWARD phase 1–2 study) https:/…
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    June 22, 2025

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  • Agathokakological
    @aaish_muhammad (Twitter)

    RT @NEJM: Original Article: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes (VX-880-101 FORWARD phase 1–2 study) https:/…
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    June 22, 2025

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  • Cristobal Morales
    @CristobMorales (Twitter)

    RT @NEJM: Original Article: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes (VX-880-101 FORWARD phase 1–2 study) https:/…
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    June 22, 2025

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  • Miki Scaravaglio
    @MScaravaglio (Twitter)

    RT @bradwouters: Exciting new clinical progress in stem cell derived therapies ⁦@UHN⁩ @UHNTransplant⁩ Stem Cell–Derived, Fully Differenti…
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    June 22, 2025

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  • Piero De Dominicis
    @dedo6923 (Twitter)

    RT @NEJM: Original Article: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes (VX-880-101 FORWARD phase 1–2 study) https:/…
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    June 22, 2025

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  • Tomas Lamas
    @TomasLamas16 (Twitter)

    RT @NEJM: Original Article: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes (VX-880-101 FORWARD phase 1–2 study) https:/…
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    June 22, 2025

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  • Ilse Daehn, PhD
    @ilse_daehn (Twitter)

    RT @KSusztak: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | ⁦@NEJM⁩ ⁦lead by @PennIDOM⁩ Mike Rickells ⁦@VertexPharma…
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    June 22, 2025

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  • Dr. Shashank Joshi
    @AskDrShashank (Twitter)

    RT @NEJM: Original Article: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes (VX-880-101 FORWARD phase 1–2 study) https:/…
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    June 22, 2025

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  • Science News
    @scinews.bsky.social (Bluesky)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes. #NEJM "zimislecel can restore physiologic islet function" Reference www.nejm.org/doi/full/10....
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    June 21, 2025

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  • Luis Ferreira Moita
    @lferreiramoita.bsky.social (Bluesky)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine www.nejm.org/doi/full/10....
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    June 21, 2025

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  • @kinesinmotors.bsky.social (Bluesky)


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    June 21, 2025

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  • Georgios Kyriakos
    @giorg_kyriakos (Twitter)


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    June 21, 2025

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  • Cravedi Lab
    @cravedilab.bsky.social (Bluesky)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine www.nejm.org/doi/full/10....
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    June 21, 2025

  • Michael Parmacek
    @michaelparmacek.bsky.social (Bluesky)

    A potentially major advance in the treatment of Type 1 Diabetes pioneered by Vertex and led by Dr. Mike Rickels of @Penn Medicine. Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine www.nejm.org/doi/full/10....
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    June 21, 2025

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  • Javi Ibarrondo
    @jibarrondo.bsky.social (Bluesky)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine www.nejm.org/doi/full/10....
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    June 21, 2025

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  • Reinold O.B. Gans
    @gansrob.bsky.social (Bluesky)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes: a cure in sight? | New England Journal of Medicine
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    June 21, 2025

  • Mustafa O. Guler
    @mustafaoguler.bsky.social (Bluesky)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes www.nejm.org/doi/full/10....
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    June 21, 2025

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  • Dr Peter Senior
    @islettx.bsky.social (Bluesky)

    Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | New England Journal of Medicine www.nejm.org/doi/full/10.... Hope this proves as transformative as the Edmonton Protocol
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    June 20, 2025

    1

Abstract Synopsis

  • The study evaluates the safety and effectiveness of zimislecel, a stem cell-derived therapy, in treating type 1 diabetes.
  • Participants underwent infusions of either a half dose or full dose of zimislecel and received glucocorticoid-free immunosuppressive therapy.
  • Results showed successful engraftment of islet cells in all 14 participants, though some serious adverse effects, including neutropenia and two deaths, were reported.