Quorum sensing in and oral microbial interactions: a scoping review.

Abstract in brief

• Quorum sensing plays a crucial role in how the major periodontal pathogen interacts with other microbes in the mouth, increasing its growth and disease-causing ability, which contributes to periodontitis.
• The review analyzed 26 studies showing that bacteria communicate using signal molecules like Autoinducer1 and Autoinducer2, which can make the bacteria more pathogenic or influence how they interact with other microbes in oral biofilms.
• Researchers are exploring quorum sensing inhibitors as potential treatments to reduce bacterial virulence and improve periodontal health, highlighting the importance of further studies on targeting quorum sensing in periodontal therapy.]