Validation and clinical implementation of cerebrospinal fluid C-reactive protein for the diagnosis of bacterial meningitis: a prospective diagnostic accuracy study.

Sabine E Olie, Steven L Staal, Nina S Groeneveld, Hans H M Schotman, Jacob Bodilsen, Henrik Nielsen, Merijn W Bijlsma, Diederik van de Beek, Matthijs C Brouwer

June 2025 Lancet Reg Health Eur

Synopsis of Social media discussions

Discussions include mentions of the high diagnostic accuracy and the practical benefits of CSF CRP testing, such as ‘cost-effective’ and ‘significant added value.’ The tone is cautiously optimistic, with language like ‘feasible and reliable,’ indicating a balanced appreciation of the research’s potential impact without overstatement.

A
Agreement
 Moderate agreement

Most discussions recognize the validity and usefulness of the study’s findings, supporting the clinical value of measuring CSF CRP for bacterial meningitis diagnosis.

I
Interest
 Moderate level of interest

Communications reflect moderate interest, with some posts highlighting the significance of improved diagnostic methods but not expressing strong enthusiasm.

E
Engagement
 Moderate level of engagement

Posts show an average level of engagement, referencing the study’s methodology and potential implications without deep technical critique.

I
Impact
 Moderate level of impact

There’s a consensus that the study could have a meaningful effect on clinical practices, considering the emphasis on feasibility and diagnostic accuracy.

Social Mentions

YouTube

1 Videos

Twitter

4 Posts

Blogs

3 Articles

News

9 Articles

Metrics

Video Views

50

Total Likes

6

Extended Reach

16,208

Social Features

17

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

WHO Guidelines on Meningitis Diagnosis and Management Explained

WHO Guidelines on Meningitis Diagnosis and Management Explained

Meningitis remains a major global health threat with an estimated 25 million cases each year. The WHO's first-ever guideline on meningitis diagnosis and management includes key recommendations for effective detection and treatment.

CMI Communications

June 29, 2025

50 views

  • フルチン中年男性
    @otakutokkai (Twitter)

    RT @carpe_diem0820: Validation and clinical implementation of cerebrospinal fluid C-reactive protein for the diagnosis of bacterial meningi…
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    April 30, 2025

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  • k.h3q
    @090_0655 (Twitter)

    RT @carpe_diem0820: Validation and clinical implementation of cerebrospinal fluid C-reactive protein for the diagnosis of bacterial meningi…
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    April 30, 2025

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  • Mugen UJIIE (氏家 無限)
    @carpe_diem0820 (Twitter)

    Validation and clinical implementation of cerebrospinal fluid C-reactive protein for the diagnosis of bacterial meningitis: a prospective diagnostic accuracy study 細菌性髄膜炎の診断における髄液C反応性タンパク（CRP）の有用性と臨床導入：前向き診断精度研究 https://t.co/JOQwCiK5Vf https://t.co/bVTDesUPdL
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    April 30, 2025

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  • Gerard Hough
    @GerardHough (Twitter)

    Validation and clinical implementation of cerebrospinal fluid C-reactive protein for the diagnosis of bacterial meningitis: a prospective diagnostic accuracy study https://t.co/1HirksA0lo
    view full post

    April 30, 2025

Abstract Synopsis

  • The study validates that measuring C-reactive protein (CRP) levels in cerebrospinal fluid (CSF) is a highly accurate and reliable method for diagnosing bacterial meningitis across different patient groups, including adults and children.
  • The research shows that combining CSF CRP measurements with traditional CSF leukocyte counts enhances diagnostic accuracy compared to using leukocytes alone, with extremely high sensitivity and specificity.
  • The clinical implementation of CSF CRP testing is feasible, cost-effective, and provides significant added value in diagnosing bacterial meningitis, especially in settings where blood CRP testing is already routine.]