Sci Adv July 2025 PMID 40644551

Picoeukaryote-based biohybrid microrobots for active delivery in the kidney.

Zhengxing Li, Dan Wang, Hao Luan, An-Yi Chang, Zheng Fang, Lei Sun, Junyi Ji, Wei-Ting Shen, Yiyan Yu, Yiyang Yan, Shichao Ding, Jiayuan Alex Zhang, Yichen Zhang, Yifei Peng, Ronnie H Fang

Mentions

54
Peak: 46 in Jul 2025
across 4 sources since Jul 2025

Extended reach

10,923,641
potential audience

Total likes

83,373

Video views

1,685,438

Mentions per month

Jul 2025

All 46 dated mentions so far are from Jul 2025.

Where it's discussed

  • X / Twitter43 posts
  • Facebook8 posts
  • YouTube2 videos
  • Bluesky1 posts

AI synopsis

What people are saying

Discussions demonstrate high enthusiasm and positive evaluation of the article, with phrases like 'fantastic journey' and 'great collaboration' highlighting excitement. Posts emphasize the innovative use of tiny planktonic organisms for drug delivery, indicating strong engagement with the methodology and potential implications for targeted treatments in complex tissues.

AgreementStrong agreement

Most posts clearly support the significance of the research, emphasizing its innovative approach and promising results, such as mentions of 'impressive movement' and 'deep tissue penetration.'

InterestHigh interest

The discussions reflect strong curiosity, with words like 'fantastic journey' and references to 'great collaboration,' indicating enthusiasm and relevance for biomedical advancements.

EngagementHigh engagement

Several posts delve into detailed descriptions of the microrobots' capabilities and methods, such as autonomous navigation and safety over 48 hours, showing deep engagement with the research findings.

ImpactModerate impact

While there is recognition of the potential transformative impact, some posts suggest a cautious tone regarding immediate applications, hence a slightly lower score for perceived impact.

Abstract in brief

  • Confined spaces in the human body create significant hurdles for biomedical procedures, making precise drug delivery crucial for effective treatments.
  • Microrobots, particularly a biohybrid design using picoeukaryotes, show great promise as they can navigate these tight spots effectively for active drug delivery.
  • These microrobots demonstrate impressive movement in vitro and achieve excellent results in vivo, showing the ability to penetrate and distribute within the kidney while remaining safe and functional for over 48 hours.

Top posts

Most liked on X and Bluesky
Science Magazine
@ScienceMagazine · X

Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organisms, that delivers drugs to the kidney in mice through autonomous navigation and deep tissue penetration. Learn more: https://t.co/rxyNkHXeOB https://t.co/Sk5be0hX1L

Jul 19, 2025 · 189 likes · 57 shares · 4,526,669 followers View post →
Science Magazine
@ScienceMagazine · X

Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organisms, that delivers drugs to the kidney in mice through autonomous navigation and deep tissue penetration. https://t.co/m2XRNi7wMl https://t.co/ZjcHUjomkW

Jul 13, 2025 · 183 likes · 34 shares · 4,526,669 followers View post →
Joe Wang
@JWangnano · X

Picoeukaryote-based biohybrid microrobots for active delivery in the kidney | Science Advances https://t.co/MV9kNzoDRq A Fantastic Journey of our tiny biohybrid robots into the Kidney. Great Collaboration with Liangfang Zhang’s team!!!

Jul 11, 2025 · 31 likes · 2 shares · 3,982 followers View post →
Science Advances
@ScienceAdvances · X

Researchers have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organisms, that delivers drugs to the kidney in mice through autonomous navigation and deep tissue penetration. https://t.co/HOd4Qgd94M https://t.co/4Btxg6cYq9

Jul 12, 2025 · 26 likes · 6 shares · 66,342 followers View post →
Phoenix
@Xaraphim · X

PDF of research https://t.co/DL0YvCzgH5

Jul 19, 2025 · 8 likes · 9,494 followers View post →
ParaMicroBio 
@ParaMicroBio · X

Microrrobots biohíbridos basados en picoeucariotas para administración activa en el riñón https://t.co/pL4GKh3EG9 https://t.co/POtvpUvydz

Jul 14, 2025 · 4 likes · 2 shares · 6,431 followers View post →

All mentions

Reddit Journal of Science
@rsciencejournal · X

Biohybrid micro-robot based on tiny plankton delivers drugs to kidney in mice via deep tissue penetration and autonomous navigation in complex branching channels https://t.co/6oN17G5P72

Jul 21, 2025 · 331 followers View post →
Ken Gusler
@kgusler · X

Picoeukaryote-based biohybrid microrobots for active delivery in the kidney - https://t.co/LpjEV0UuUE

Jul 21, 2025 · 20,028 followers View post →
Phoenix
@Xaraphim · X

PDF of research https://t.co/DL0YvCzgH5

Jul 19, 2025 · 8 likes · 9,494 followers View post →
Hilra Senev
@HilraSenev · X

RT @ScienceMagazine: Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organis…

Jul 19, 2025 · 57 shares · 57 followers View post →
Dr Niranjan MR @ NephroByte MD DM DNB
@drniranjanmr2 · X

RT @ScienceMagazine: Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organis…

Jul 19, 2025 · 57 shares · 897 followers View post →
Juan
@jctoyzhut · X

RT @ScienceMagazine: Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organis…

Jul 19, 2025 · 57 shares · 2,457 followers View post →
Namphungo
@Waterbee_19 · X

RT @ScienceMagazine: Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organis…

Jul 19, 2025 · 57 shares View post →
Wei Roc Song
@WeiRocSong · X

RT @ScienceMagazine: Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organis…

Jul 19, 2025 · 57 shares · 97 followers View post →
Félix Pastor
@felix4better · X

RT @ScienceMagazine: Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organis…

Jul 19, 2025 · 57 shares · 24 followers View post →
Manoj Mayogi Mishra
@mayogisense · X

RT @ScienceMagazine: Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organis…

Jul 19, 2025 · 57 shares · 573 followers View post →
Sanath Janaka Gunawardena
@5anath666 · X

RT @ScienceMagazine: Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organis…

Jul 19, 2025 · 57 shares · 707 followers View post →
Vicente Ortiz
@ortizaimed · X

RT @ScienceMagazine: Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organis…

Jul 19, 2025 · 57 shares · 38 followers View post →
Deimar Perea Moreno
@DeimarPerea · X

RT @ScienceMagazine: Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organis…

Jul 19, 2025 · 57 shares · 486 followers View post →
Juan ka'
@JnKaltenbrunner · X

RT @ScienceMagazine: Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organis…

Jul 19, 2025 · 57 shares · 1,662 followers View post →
MINE
@ThePhantomofOp3 · X

https://t.co/2xXQs9L82v

Jul 19, 2025 · 389 followers View post →
Raymond Flores
@FloresRaymondIV · X

RT @ScienceMagazine: Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organis…

Jul 19, 2025 · 57 shares · 1,839 followers View post →
Wendelin Kraus
@wende18196 · X

RT @ScienceMagazine: Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organis…

Jul 19, 2025 · 57 shares · 1 followers View post →
soda_troubles,https://med-mastodon.com/@haysam
@set_fortess · X

RT @ScienceMagazine: Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organis…

Jul 19, 2025 · 57 shares · 2,548 followers View post →
mohamed zubair
@zubeyr · X

RT @ScienceMagazine: Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organis…

Jul 19, 2025 · 57 shares · 628 followers View post →
v
@TheManInBlackZ · X

RT @ScienceMagazine: Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organis…

Jul 19, 2025 · 57 shares · 15 followers View post →
For Yet Better Science
@ForYetBetterSci · X

RT @ScienceMagazine: Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organis…

Jul 19, 2025 · 57 shares · 866 followers View post →
Nex
@Guarionexflores · X

RT @ScienceMagazine: Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organis…

Jul 19, 2025 · 57 shares · 628 followers View post →
Komal Saroj
@KomalSaroj12 · X

RT @ScienceMagazine: Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organis…

Jul 19, 2025 · 57 shares · 282 followers View post →
Science Magazine
@ScienceMagazine · X

Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organisms, that delivers drugs to the kidney in mice through autonomous navigation and deep tissue penetration. Learn more: https://t.co/rxyNkHXeOB https://t.co/Sk5be0hX1L

Jul 19, 2025 · 189 likes · 57 shares · 4,526,669 followers View post →
BreakthroughMedicine&AdvancedResearchTools
@JayChance12 · X

RT @LifeboatHQ: Picoeukaryote-based biohybrid microrobots for active delivery in the kidney https://t.co/WEUf4gZtBg

Jul 18, 2025 · 1 share · 627 followers View post →
Lifeboat Foundation
@LifeboatHQ · X

Picoeukaryote-based biohybrid microrobots for active delivery in the kidney https://t.co/WEUf4gZtBg

Jul 17, 2025 · 1 share · 31,612 followers View post →
MEDNTD
@medntdj · X

Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organisms, that delivers drugs to the kidney in mice through autonomous navigation and deep tissue penetration. https://t.co/rGnA8468Pe https://t.co/449wGwbSYS

Jul 14, 2025 · 916 followers View post →
Cameron Thrash
@jcamthrash.bsky.social · Bluesky

Picoeukaryote-based biohybrid microrobots for active delivery in the kidney www.science.org/doi/full/10.... #jcampubs

Jul 14, 2025 · 1 like · 1 share View post →
Cameron Thrash
@jcamthrash · X

Picoeukaryote-based biohybrid microrobots for active delivery in the kidney https://t.co/CS789bDoaX

Jul 14, 2025 · 3 likes · 17,456 followers View post →
Lorenzo Gutiérrez
@Lojoga · X

RT @ParaMicroBio: Microrrobots biohíbridos basados en picoeucariotas para administración activa en el riñón https://t.co/pL4GKh3EG9 https:…

Jul 14, 2025 · 2 shares · 591 followers View post →
ParaMicroBio 
@ParaMicroBio · X

Microrrobots biohíbridos basados en picoeucariotas para administración activa en el riñón https://t.co/pL4GKh3EG9 https://t.co/POtvpUvydz

Jul 14, 2025 · 4 likes · 2 shares · 6,431 followers View post →
space✨
@lethal___laser · X

RT @ScienceMagazine: Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organis…

Jul 13, 2025 · 34 shares · 1,691 followers View post →
Withthehelpofmyfriends
@Withthehelpofm1 · X

RT @ScienceMagazine: Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organis…

Jul 13, 2025 · 34 shares · 3,114 followers View post →
Lil Richard Jünge Swinburne Herp
@HerpEmperor · X

RT @ScienceMagazine: Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organis…

Jul 13, 2025 · 34 shares · 1,082 followers View post →
GOON MASTER SOPHONT SIMP
@SOPHONTSIMP · X

RT @ScienceMagazine: Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organis…

Jul 13, 2025 · 34 shares · 1,572 followers View post →
♬∞Punch♏︎Tsubasa☉☯
@PunchSakura · X

RT @ScienceMagazine: Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organis…

Jul 13, 2025 · 34 shares · 69 followers View post →
Dorohedoro
@Rodrigo_Couto · X

RT @ScienceMagazine: Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organis…

Jul 13, 2025 · 34 shares · 119 followers View post →
Makate Meshack Tebeila
@MeshackTebeila · X

RT @ScienceMagazine: Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organis…

Jul 13, 2025 · 34 shares · 1,223 followers View post →
Science Magazine
@ScienceMagazine · X

Researchers in @ScienceAdvances have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organisms, that delivers drugs to the kidney in mice through autonomous navigation and deep tissue penetration. https://t.co/m2XRNi7wMl https://t.co/ZjcHUjomkW

Jul 13, 2025 · 183 likes · 34 shares · 4,526,669 followers View post →
Barbiee'_BO
@Blue_BarbaraBO · X

RT @ScienceAdvances: Researchers have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organisms, that delivers dr…

Jul 12, 2025 · 6 shares View post →
Science Advances
@ScienceAdvances · X

Researchers have developed a biohybrid microrobot based on picoeukaryotes, tiny planktonic organisms, that delivers drugs to the kidney in mice through autonomous navigation and deep tissue penetration. https://t.co/HOd4Qgd94M https://t.co/4Btxg6cYq9

Jul 12, 2025 · 26 likes · 6 shares · 66,342 followers View post →
María Pedrero Muñoz
@MariaPedreroM · X

RT @JWangnano: Picoeukaryote-based biohybrid microrobots for active delivery in the kidney | Science Advances https://t.co/MV9kNzoDRq A Fa…

Jul 12, 2025 · 2 shares · 76 followers View post →
Nanomotor Update
@nanomotorupdate · X

RT @JWangnano: Picoeukaryote-based biohybrid microrobots for active delivery in the kidney | Science Advances https://t.co/MV9kNzoDRq A Fa…

Jul 11, 2025 · 2 shares · 1,042 followers View post →
Joe Wang
@JWangnano · X

Picoeukaryote-based biohybrid microrobots for active delivery in the kidney | Science Advances https://t.co/MV9kNzoDRq A Fantastic Journey of our tiny biohybrid robots into the Kidney. Great Collaboration with Liangfang Zhang’s team!!!

Jul 11, 2025 · 31 likes · 2 shares · 3,982 followers View post →