Nat Metab August 2025 PMID 40715760

The source of dietary fat influences anti-tumour immunity in obese mice.

Britta Kunkemoeller, Hannah Prendeville, Claire McIntyre, Ayantu Temesgen, Rόisín M Loftus, Conghui Yao, Lydia Dyck, Linda V Sinclair, Christina Rollings, Aaron Douglas, Gerard Pernes, Kathleen A J Mitchelson, Cathal Harmon, Mathilde Raverdeau, Ross Ward

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Discussions highlight the significance of the research by mentioning that butter-based oils accelerate tumor growth, and posts encourage considering fat sources in diet, using words like 'impairs,' 'accelerates,' and 'influences' to convey the findings' importance. The tone is informative yet indicates concern over dietary choices and their health consequences.

AgreementModerate agreement

Most discussions acknowledge the findings, particularly the negative effects of animal fats on anti-tumor immunity, showing general agreement with the publication's implications.

InterestModerate interest

Participants show moderate interest, often referencing specific details like butter and lard and their effects on tumor growth, indicating engagement but not extreme curiosity.

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There's some deep engagement, with posts discussing mechanisms and public health implications, such as how animal fats impair immune responses and influence cancer risk.

ImpactModerate impact

The discussions suggest the findings are seen as meaningful, especially for health-related choices, with mentions of diet and immune function that could influence public awareness and behavior.

Abstract in brief

The study finds that high-fat diets made from lard, beef tallow, or butter promote faster tumor growth in obese mice, while diets based on coconut, palm, or olive oil do not, despite all causing obesity.
The type of dietary fat affects immune cells within tumors, influencing how natural killer and CD8 T cells infiltrate and function, with butter- and palm oil-based fats having different effects.
Lipid intermediates like long-chain acylcarnitines, which are more common in butter-fed mice, seem to suppress immune responses, highlighting how the source of dietary fat can impact cancer progression by altering immune function.]

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Impact of Butter on Cancer Mortality in Large Studies

This video explores the link between butter consumption and cancer mortality, based on large-scale studies. Key mechanisms are discussed, emphasizing the dietary fat sources and their implications for health. Join the…

Physionic · Nov 3, 2025 30,002 views

Impact of Dietary Fat on Antitumor Immunity in Obese Mice

This video discusses the findings of Britta Kunkemoeller et al. on how the source of dietary fat affects antitumor immunity in obese mice. Published in Nature Metabolism, the study highlights crucial insights into…

逆齡研究所 · Aug 7, 2025 1,293 views

Choosing Cooking Oils: Impact on Tumors and Immunity

This video discusses how the source of dietary fat influences anti-tumor immunity, particularly in obese mice. Learn which cooking oils may be more beneficial for health and how they affect tumor growth.

Dr.胞孢籽不包包子 · Aug 19, 2025 158 views

Dr.胞孢籽

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食用油怎么选? l 肿瘤喜欢什么油？食用油的猫腻 l 古法榨油的智商税 l 芥花油 How to Choose Cooking Oil? | W... https://t.co/V0xM9iboT1 来自 @YouTube

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The source of dietary fat influences anti-tumour immunity in obese mice #MedEd #medx #TICMED25 Reference https://t.co/9F7tQLjIP4 https://t.co/8rEUuYUejy https://t.co/8pIfaqpa3G

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キャスバルレムダイクン@learning medicine student.

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ForensicPsyMD

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The source of dietary fat influences anti-tumour immunity in obese mice | Nature Metabolism https://t.co/WGyVcqNYRH

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Beiruttime-lb.com

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تجد الدراسة أن الدهون التي تعتمد على حيوانات الحيوانات في الوقود نمو الورم في الفئران السمنة ، والدهون النباتية لا حمية عالية الدهون تسبب السمنة ويضعف الأيض الجهازي ، بغض النظر عن مصدر الدهون الغذائية. ائتمان: استقلاب الطبيعة (2025). doi: 10.1038/s42255-025-01330-W السمنة ترفع خطر ما لا يقل عن 13…

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Today headline

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Study finds animal-based fats fuel tumor growth in obese mice, plant fats do not High fat diet causes obesity and impairs systemic metabolism, regardless of dietary fat source. Credit: Nature Metabolism (2025). DOI: 10.1038/s42255-025-01330-w Obesity elevates the risk of at least 13 major cancers,…

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Climate, Ecology, War & More by Dr. Glen Barry, BigEarthData.ai

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The source of dietary fat influences anti-tumour immunity in obese mice | Nature Metabolism https://t.co/CJLU22mTgR

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The source of dietary fat influences anti-tumour immunity in obese mice #immunometabolism Great work from @lydialynch.bsky.social lab and colleagues www.nature.com/articles/s42...

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The source of dietary fat influences anti-tumour immunity in obese mice.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Impact of Butter on Cancer Mortality in Large Studies

Impact of Dietary Fat on Antitumor Immunity in Obese Mice

Choosing Cooking Oils: Impact on Tumors and Immunity