Synopsis of Social media discussions
Overall, the discussions reflect excitement and support, with examples such as mentions of HAR123's potential for modifying intelligence and its evolutionary significance, highlighting how the language and focused references convey the importance and potential impact of the study.
Agreement
Moderate agreementMost discussions express strong support or interest in the findings, viewing them as significant advances in understanding human brain development.
Interest
High level of interestPosts show high curiosity, with many referencing potential implications for intelligence and creativity, indicating active engagement.
Engagement
Moderate level of engagementUsers often reference specific details like HAR123's role or the evolutionary aspects, suggesting some depth of analysis.
Impact
Moderate level of impactThe tone implies that this research could be a key breakthrough with broad biological and technological consequences.
Social Mentions
YouTube
4 Videos
Bluesky
4 Posts
41 Posts
Blogs
8 Articles
News
24 Articles
Metrics
Video Views
180,741
Total Likes
2,263
Extended Reach
2,240,247
Social Features
81
Timeline: Posts about article
Top Social Media Posts
Medical Xpress
#A specific human-accelerated region, HAR123, acts as a transcriptional enhancer influencing neural progenitor cell development and may underlie advanced cognitive flexibility unique to humans. @ucsandiego @ScienceAdvances https://t.co/kiKyCR9zhr https://t.co/D8Kr2JAwrm
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Chris Stringer
An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Science Advances https://t.co/uW8lgxp1Qo
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Neuroscience News
“An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility” by Miles Wilkinson et al. Science Advances
https://t.co/M0dgcwJ7cj
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Agingdoc
An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility
“The genetic changes driving the evolution of humans since the human-chimpanzee split have been elusive. Here, we report a promising candidate…” https://t.co/A6NlQMRuPa
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Chris Stringer
An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Science Advances https://t.co/uW8lgxp1Qo
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Posts referencing the article
Evolutionary Neural Enhancer Influences Human Brain Development and Cognition
Researchers identified a chromosomal region linked to neurological development that has evolved since humans and chimpanzees split. The 442-nucleotide HAR123 enhancer promotes neural progenitor formation and affects cognitive flexibility. Knockout mice exhibit neural and behavioral changes.
August 25, 2025
177,995 views
Tiny DNA Switch Influences Human Brain Development and Intelligence
Scientists at UC San Diego discovered HAR123, a hidden genetic control that influences brain cell growth and neural development, potentially explaining human cognitive abilities and related disorders like autism.
August 17, 2025
1,110 views
Ancient DNA Uncovers Indigenous Caribbean History and Genetic Insights
A 2023 study in Science Advances analyzed ancient DNA from Puerto Rico, revealing ancestral lineages of Indigenous Caribbean peoples long before European contact. The research uncovers genetic signatures that persist today and highlights evolutionary innovations in human neural development.
August 16, 2025
960 views
Enhancer Evolving in Human Lineage Promotes Neural Development and Cognition
Researchers identify a chromosomal region linked to neurological development that has evolved since humans and chimpanzees split. The specific enhancer, HAR123, influences neural progenitor cell formation and cognitive flexibility, with implications for neurodevelopmental disorders.
September 7, 2025
677 views
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An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Science Advances https://t.co/b5YxWnrnKw
view full postNovember 5, 2025
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CivilisatioTransform
@CapabilitYes (Twitter)RT @LifeboatHQ: An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility https://t.c…
view full postAugust 30, 2025
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Yang Xu
@coriana_galesky (Twitter)人為什麼進化成人？442→9→大腦升級 | 雅桑了嗎 https://t.co/JzjiYcntdI 来自 @YouTube
view full postAugust 26, 2025
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Ajai Pathak
@apatk (Twitter)RT @ChrisStringer65: An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Scie…
view full postAugust 23, 2025
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Pec@
@PecoAz (Twitter)RT @ChrisStringer65: An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Scie…
view full postAugust 23, 2025
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Chris Stringer
@ChrisStringer65 (Twitter)RT @ChrisStringer65: An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Scie…
view full postAugust 23, 2025
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CRCpaleos
@CRCpaleos (Twitter)ARTÍCULO REFERENCIA (acceso abierto) An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility https://t.co/i5HA6LDw80 vía @ScienceAdvances https://t.co/LZpcifT3DN
view full postAugust 23, 2025
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Miguel Angel Contreras Sieck
@MiguelSieck (Twitter)RT @ChrisStringer65: An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Scie…
view full postAugust 22, 2025
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Siberian fox
@SilverVVulpes (Twitter)RT @ChrisStringer65: An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Scie…
view full postAugust 22, 2025
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Alexander Kruel
@XiXiDu (Twitter)RT @rexjung: (HAR) 123 potential for modification in human intelligence (and perhaps creativity) given its role in "cognitive flexibility a…
view full postAugust 22, 2025
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Zeke Darwin
@Zeke_Darwin (Twitter)RT @ChrisStringer65: An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Scie…
view full postAugust 22, 2025
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Val Giddings
@prometheusgreen (Twitter)RT @ChrisStringer65: An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Scie…
view full postAugust 22, 2025
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Chris Stringer
@ChrisStringer65 (Twitter)An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Science Advances https://t.co/uW8lgxp1Qo
view full postAugust 22, 2025
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Lifeboat Foundation
@LifeboatHQ (Twitter)An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility https://t.co/lNqb8WXYJs
view full postAugust 22, 2025
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Rex Jung
@rexjung (Twitter)(HAR) 123 potential for modification in human intelligence (and perhaps creativity) given its role in "cognitive flexibility and a shift in neural-glia ratio(s)" - study in mice embryos and cell cultures though...: https://t.co/rFUdwkoaHF
view full postAugust 21, 2025
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Emerald Perlas
@emeraldaperlas.bsky.social (Bluesky)An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Science Advances www.science.org/doi/10.1126/...
view full postAugust 20, 2025
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MU-Peter Shimon
@mu-peter.bsky.social (Bluesky)A genetic region, HAR123, may help explain what makes the human brain unique. An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility
view full postAugust 18, 2025
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Sara Nicolau
@SaraSnicolau (Twitter)RT @social_brains: Scientists may have found the genetic mutation that led humans to have bigger brains. If it can be modulated that would…
view full postAugust 17, 2025
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Reinis Lazda
@ReinisLazda (Twitter)RT @social_brains: Scientists may have found the genetic mutation that led humans to have bigger brains. If it can be modulated that would…
view full postAugust 17, 2025
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Stephen Pimentel
@StephenPiment (Twitter)https://t.co/OMKDiKdyrx
view full postAugust 17, 2025
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Matt Lieberman
@social_brains (Twitter)Scientists may have found the genetic mutation that led humans to have bigger brains. If it can be modulated that would have huge consequences for the future. https://t.co/CErENB1uU4
view full postAugust 17, 2025
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BreakthroughMedicine&AdvancedResearchTools
@JayChance12 (Twitter)RT @Dr_Singularity: paper https://t.co/XWk4ZbfWGs
view full postAugust 17, 2025
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な bot
@NeuroNNNNN_bot (Twitter)[Sci. Adv.] An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility https://t.co/SwDokfYfEr
view full postAugust 16, 2025
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Miguel Angel Contreras Sieck
@MiguelSieck (Twitter)https://t.co/y9xPa2WkWo
view full postAugust 16, 2025
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Tip News
@TipNewsHeadline (Twitter)An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility (Science) https://t.co/5ddJeME7MU
view full postAugust 16, 2025
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Ordo Fraterna Fibonacci
@OrdoFibonacci (Twitter)An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility Science Advances https://t.co/kzboyMW1kY
view full postAugust 16, 2025
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Ordo Fraterna Fibonacci
@ordofibonacci.bsky.social (Bluesky)An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility Science Advances www.science.org/doi/10.1126/...
view full postAugust 16, 2025
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Ralph Cerchione
@Dry_Observer (Twitter)RT @Dr_Singularity: paper https://t.co/XWk4ZbfWGs
view full postAugust 15, 2025
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Javi Ciborro
@papayaykware (Twitter)https://t.co/Q8OFSXTrUo
view full postAugust 15, 2025
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Dr Singularity
@Dr_Singularity (Twitter)paper https://t.co/XWk4ZbfWGs
view full postAugust 15, 2025
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Chris Stringer
@ChrisStringer65 (Twitter)RT @ChrisStringer65: An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Scie…
view full postAugust 15, 2025
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Komolafe John
@JohnnyKomolafe (Twitter)RT @NeuroscienceNew: “An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility” by M…
view full postAugust 15, 2025
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Chris Stringer
@ChrisStringer65 (Twitter)An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Science Advances https://t.co/uW8lgxp1Qo
view full postAugust 15, 2025
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Dr. Gennadi Glinsky, MD, Ph.D.
@gglinskii (Twitter)An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Science Advances https://t.co/3pGFKhv2pT
view full postAugust 15, 2025
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Agingdoc
@agingdoc1 (Twitter)An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility “The genetic changes driving the evolution of humans since the human-chimpanzee split have been elusive. Here, we report a promising candidate…” https://t.co/A6NlQMRuPa
view full postAugust 14, 2025
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autisme info
@AutismeInfo (Twitter)An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility https://t.co/160Ge6oaB3
view full postAugust 14, 2025
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DR. Rich Miglecz
@MigleczRich (Twitter)RT @medical_xpress: #A specific human-accelerated region, HAR123, acts as a transcriptional enhancer influencing neural progenitor cell dev…
view full postAugust 14, 2025
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@EzTreez (Twitter)RT @medical_xpress: #A specific human-accelerated region, HAR123, acts as a transcriptional enhancer influencing neural progenitor cell dev…
view full postAugust 14, 2025
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Medical Xpress
@medical_xpress (Twitter)#A specific human-accelerated region, HAR123, acts as a transcriptional enhancer influencing neural progenitor cell development and may underlie advanced cognitive flexibility unique to humans. @ucsandiego @ScienceAdvances https://t.co/kiKyCR9zhr https://t.co/D8Kr2JAwrm
view full postAugust 14, 2025
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Phys.org
@physorg_com (Twitter)RT @medical_xpress: #A specific human-accelerated region, HAR123, acts as a transcriptional enhancer influencing neural progenitor cell dev…
view full postAugust 14, 2025
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Javier DN
@javierdn.bsky.social (Bluesky)An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility. While present in all mammals, HAR123 has rapidly evolved since humans diverged from chimpanzees. www.science.org/doi/10.1126/...
view full postAugust 14, 2025
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Ⓓ Ⓒ Ⓝ ㋡ ≡ ∀ ≡
@DCNChannel (Twitter)Твит с неудавшимся комментарием не ушёл может и к лучшему там просто ссылку https://t.co/t3vdbbN6js
view full postAugust 14, 2025
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Dr Anthony Martin
@AMAinsight (Twitter)An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Science Advances https://t.co/YDYa9gW2q1
view full postAugust 13, 2025
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Neuroscience News
@NeuroscienceNew (Twitter)“An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility” by Miles Wilkinson et al. Science Advances https://t.co/M0dgcwJ7cj
view full postAugust 13, 2025
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Kun Tan
@KunTan534067 (Twitter)An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Science Advances https://t.co/wKTgHYOkOQ
view full postAugust 13, 2025
Abstract Synopsis
- Researchers identified a chromosomal region (17p13.3) linked to neurological development that has evolved since humans and chimpanzees split.
- A specific 442-nucleotide sequence, HAR123, enhances the formation of neural progenitor cells and shows differences in effects on neural development between humans and chimpanzees.
- HAR123-knockout mice display cognitive flexibility issues and changes in the neural-glia ratio in the hippocampus, suggesting connections to neurodevelopmental disorders.
Dr. Gennadi Glinsky, MD, Ph.D.
@gglinskii (Twitter)