#A specific human-accelerated region, HAR123, acts as a transcriptional enhancer influencing neural progenitor cell development and may underlie advanced cognitive flexibility unique to humans. @ucsandiego @ScienceAdvances https://t.co/kiKyCR9zhr https://t.co/D8Kr2JAwrm
An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility.
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Aug 2025 – Nov 2025Where it's discussed
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X / Twitter41 posts
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News24 articles
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Blogs8 articles
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Bluesky4 posts
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YouTube4 videos
AI synopsis
What people are saying
Overall, the discussions reflect excitement and support, with examples such as mentions of HAR123's potential for modifying intelligence and its evolutionary significance, highlighting how the language and focused references convey the importance and potential impact of the study.
Most discussions express strong support or interest in the findings, viewing them as significant advances in understanding human brain development.
Posts show high curiosity, with many referencing potential implications for intelligence and creativity, indicating active engagement.
Users often reference specific details like HAR123's role or the evolutionary aspects, suggesting some depth of analysis.
The tone implies that this research could be a key breakthrough with broad biological and technological consequences.
Abstract in brief
- Researchers identified a chromosomal region (17p13.3) linked to neurological development that has evolved since humans and chimpanzees split.
- A specific 442-nucleotide sequence, HAR123, enhances the formation of neural progenitor cells and shows differences in effects on neural development between humans and chimpanzees.
- HAR123-knockout mice display cognitive flexibility issues and changes in the neural-glia ratio in the hippocampus, suggesting connections to neurodevelopmental disorders.
Top posts
Most liked on X and BlueskyAn ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Science Advances https://t.co/uW8lgxp1Qo
“An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility” by Miles Wilkinson et al. Science Advances https://t.co/M0dgcwJ7cj
An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility “The genetic changes driving the evolution of humans since the human-chimpanzee split have been elusive. Here, we report a promising candidate…” https://t.co/A6NlQMRuPa
An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Science Advances https://t.co/uW8lgxp1Qo
paper https://t.co/XWk4ZbfWGs
All mentions
Evolutionary Neural Enhancer Influences Human Brain Development and Cognition
Researchers identified a chromosomal region linked to neurological development that has evolved since humans and chimpanzees split. The 442-nucleotide HAR123 enhancer promotes neural progenitor formation and affects…
Tiny DNA Switch Influences Human Brain Development and Intelligence
Scientists at UC San Diego discovered HAR123, a hidden genetic control that influences brain cell growth and neural development, potentially explaining human cognitive abilities and related disorders like autism.
Ancient DNA Uncovers Indigenous Caribbean History and Genetic Insights
A 2023 study in Science Advances analyzed ancient DNA from Puerto Rico, revealing ancestral lineages of Indigenous Caribbean peoples long before European contact. The research uncovers genetic signatures that persist…
Enhancer Evolving in Human Lineage Promotes Neural Development and Cognition
Researchers identify a chromosomal region linked to neurological development that has evolved since humans and chimpanzees split. The specific enhancer, HAR123, influences neural progenitor cell formation and cognitive…
An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Science Advances https://t.co/b5YxWnrnKw
RT @LifeboatHQ: An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility https://t.c…
人為什麼進化成人?442→9→大腦升級 | 雅桑了嗎 https://t.co/JzjiYcntdI 来自 @YouTube
RT @ChrisStringer65: An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Scie…
RT @ChrisStringer65: An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Scie…
RT @ChrisStringer65: An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Scie…
ARTÍCULO REFERENCIA (acceso abierto) An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility https://t.co/i5HA6LDw80 vía @ScienceAdvances https://t.co/LZpcifT3DN
RT @ChrisStringer65: An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Scie…
RT @ChrisStringer65: An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Scie…
RT @rexjung: (HAR) 123 potential for modification in human intelligence (and perhaps creativity) given its role in "cognitive flexibility a…
RT @ChrisStringer65: An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Scie…
RT @ChrisStringer65: An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Scie…
An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Science Advances https://t.co/uW8lgxp1Qo
An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility https://t.co/lNqb8WXYJs
(HAR) 123 potential for modification in human intelligence (and perhaps creativity) given its role in "cognitive flexibility and a shift in neural-glia ratio(s)" - study in mice embryos and cell cultures though...: https://t.co/rFUdwkoaHF
An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Science Advances www.science.org/doi/10.1126/...
A genetic region, HAR123, may help explain what makes the human brain unique. An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility
RT @social_brains: Scientists may have found the genetic mutation that led humans to have bigger brains. If it can be modulated that would…
RT @social_brains: Scientists may have found the genetic mutation that led humans to have bigger brains. If it can be modulated that would…
https://t.co/OMKDiKdyrx
Scientists may have found the genetic mutation that led humans to have bigger brains. If it can be modulated that would have huge consequences for the future. https://t.co/CErENB1uU4
RT @Dr_Singularity: paper https://t.co/XWk4ZbfWGs
[Sci. Adv.] An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility https://t.co/SwDokfYfEr
https://t.co/y9xPa2WkWo
An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility (Science) https://t.co/5ddJeME7MU
An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility Science Advances https://t.co/kzboyMW1kY
An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility Science Advances www.science.org/doi/10.1126/...
RT @Dr_Singularity: paper https://t.co/XWk4ZbfWGs
https://t.co/Q8OFSXTrUo
paper https://t.co/XWk4ZbfWGs
RT @ChrisStringer65: An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Scie…
RT @NeuroscienceNew: “An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility” by M…
An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Science Advances https://t.co/uW8lgxp1Qo
An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Science Advances https://t.co/3pGFKhv2pT
An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility “The genetic changes driving the evolution of humans since the human-chimpanzee split have been elusive. Here, we report a promising candidate…” https://t.co/A6NlQMRuPa
An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility https://t.co/160Ge6oaB3
RT @medical_xpress: #A specific human-accelerated region, HAR123, acts as a transcriptional enhancer influencing neural progenitor cell dev…
RT @medical_xpress: #A specific human-accelerated region, HAR123, acts as a transcriptional enhancer influencing neural progenitor cell dev…
#A specific human-accelerated region, HAR123, acts as a transcriptional enhancer influencing neural progenitor cell development and may underlie advanced cognitive flexibility unique to humans. @ucsandiego @ScienceAdvances https://t.co/kiKyCR9zhr https://t.co/D8Kr2JAwrm
RT @medical_xpress: #A specific human-accelerated region, HAR123, acts as a transcriptional enhancer influencing neural progenitor cell dev…
An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility. While present in all mammals, HAR123 has rapidly evolved since humans diverged from chimpanzees. www.science.org/doi/10.1126/...
Твит с неудавшимся комментарием не ушёл может и к лучшему там просто ссылку https://t.co/t3vdbbN6js
An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Science Advances https://t.co/YDYa9gW2q1
“An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility” by Miles Wilkinson et al. Science Advances https://t.co/M0dgcwJ7cj
An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility | Science Advances https://t.co/wKTgHYOkOQ
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