N Engl J Med September 2025 PMID 40879434

Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction.

Udo Bavendiek, Anika Großhennig, Johannes Schwab, Dominik Berliner, Andreas Rieth, Lars S Maier, Thomas Gaspar, Nele Henrike Thomas, Xiaofei Liu, Sven Schallhorn, Eleonora Angelini, Samira Soltani, Fabian Rathje, Mircea-Andrei Sandu, Welf Geller

Mentions

215
Peak: 124 in Sep 2025
across 5 sources since Aug 2025

Extended reach

3,935,763
potential audience

Total likes

408

Video views

858

Mentions per month

Aug 2025 – Oct 2025

Where it's discussed

  • X / Twitter182 posts
  • News21 articles
  • Bluesky6 posts
  • YouTube4 videos
  • Blogs2 articles

AI synopsis

What people are saying

Numerous discussions highlight key findings from the study, such as 'Digitoxin reduces death and hospitalization risk in heart failure patients, outperforming placebo' which resonates strongly with healthcare professionals. The engagement level is amplified by phrases like 'fantastic finding' and inquiries about incorporating digitoxin into current therapies, showcasing a proactive approach to the material. The tone reflects a sense of urgency and excitement, indicating a collaborative spirit among users as they discuss possible shifts in treatment paradigms.

AgreementStrong agreement

The majority of discussions express strong support for the findings, emphasizing the effectiveness of digitoxin compared to placebo.

InterestHigh interest

Users show high curiosity regarding the implications of digitoxin treatment, reflecting on its potential role in clinical practice.

EngagementHigh engagement

Many posts delve into detailed analysis of the study's methodology and outcomes, creating a rich dialogue around its findings.

ImpactHigh impact

Contributors view the publication as having considerable influence on future heart failure treatment protocols, noting its potential to change clinical practices.

Abstract in brief

  • The study tested the effectiveness of digitoxin, a cardiac glycoside, in patients with chronic heart failure and reduced ejection fraction compared to a placebo.
  • Over the 36-month trial involving 1,212 patients, those receiving digitoxin experienced a lower rate of death or hospitalization for worsening heart failure.
  • While digitoxin was associated with fewer primary outcome events, it also had a higher incidence of serious adverse events compared to the placebo group.

Top posts

Most liked on X and Bluesky
NEJM
@NEJM · X

Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8mpwOpVo7U Editorial: Digitoxin — A Reminder for Digoxin https://t.co/oBEX3T6z8s #Cardiology https://t.co/RsSBar1xpL

Sep 26, 2025 · 117 likes · 32 shares · 935,883 followers View post →
NEJM
@NEJM · X

New in the September 25, 2025, issue of NEJM: Digitoxin in Heart Failure with Reduced EF (DIGIT-HF phase 4 trial) https://t.co/8mpwOpVo7U Apixaban for Provoked Venous Thromboembolism (HI-PRO trial) https://t.co/Epe4Q957pV Measurable Residual Disease–Guided Therapy for CLL https://t.co/8e5qUOXjY6

Sep 25, 2025 · 36 likes · 7 shares · 935,883 followers View post →
Robert Kalyesubula,MD, FISN(USA), PhD-FRCP(London)
@rkalyes1 · X

✍️ Digitoxin (not digoxin this time) still has a roll in HFrEF but you must keep that dose low! ✍️Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction | New England Journal of Medicine @ChefKarim02 @DrOribaDan @DrJNELLY95 https://t.co/Dlv3aEO5Ap?

Sep 28, 2025 · 33 likes · 9 shares · 18,867 followers View post →
真鍋晋@心臓外科医
@Susumu_Manabe · X

ガイドライン推奨薬を使用している低心機能、心不全患者に、 ジゴキシンを加えることで、総死亡、心不全入院が低下傾向となり、複合エンドポイントは有意に低下。1,240例を対象にした無作為化比較試験https://t.co/R4IVpTibZR

Sep 24, 2025 · 25 likes · 1 share · 2,326 followers View post →
Medical Xpress
@medical_xpress · X

Digitoxin, derived from red foxglove, significantly reduces mortality and hospitalizations in patients with advanced HFrEF, offering a safe and cost-effective treatment option—even with kidney impairment. @nejm https://t.co/aF3DT0CEbC https://t.co/4jBRQCe2gm

Aug 29, 2025 · 19 likes · 15 shares · 173,093 followers View post →
ACCP Cardiology PRN
@accpcardprn · X

#WNW Gotta talk about DIGIT-HF. In pts with HFrEF (EF ~29%, 67% class III) on GDMT (though <20% were on SGLT2i), adding digitoxin vs placebo lowered risk of all-cause death or 1st HFH (39.5% vs 44.1%) over 36 months. https://t.co/JHRx2mWr1E

Sep 10, 2025 · 17 likes · 3 shares · 9,295 followers View post →

All mentions

Revista MFAndalucia
@RevistaMFSamfyc · X

Digitoxina en pacientes con insuficiencia cardiaca y fracción de eyección reducida https://t.co/PtZqwcpFFa PMID 40879434

Oct 10, 2025 · 723 followers View post →
STITCHES Medicine - the Best of Medical Research
@medicine.stitches.today · Bluesky

Digitoxin reduces death and hospitalization risk in heart failure patients, outperforming placebo in a substantial clinical trial. by Bavendiek U, Großhennig A (...) Bauersachs J et 32 al. in N Engl J Med #MedSky

Oct 4, 2025 · 7 likes · 2 shares View post →
STITCHES Medicine - the Best of Medical Research
@STITCHESMed · X

Digitoxin reduces death and hospitalization risk in heart failure patients, outperforming placebo in a substantial clinical trial. by Bavendiek U, Großhennig A (...) Bauersachs J et 32 al. in N Engl J Med https://t.co/Kscsr0lse6 #MedX #MedResearch

Oct 4, 2025 · 85 followers View post →
prem choudhary
@premcho85486011 · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Oct 2, 2025 · 32 shares · 83 followers View post →
Javier Armendáriz
@javier_armz98 · X

Oct 2, 2025 · 127 followers View post →
Javier Armendáriz
@javier_armz98 · X

El ensayo DIGIT-HF publicado en NEJM demuestra que la digitoxina reduce el riesgo combinado de muerte o reingreso por IC con FEVI reducida. Viejo fármaco, ¿nueva oportunidad? DOI: 10.1056/NEJMoa2415471 https://t.co/K4r9WjgUfA

Oct 2, 2025 · 127 followers View post →
James J. Gillespie, PhD, JD, MPA, MS
@GillespiePhDJD · X

RT @bmorecardiology: So now what? should we start adding digoxin to our pillars of therapy for HFrEF? https://t.co/xlxge3DkD2 @NEJM @gcfmd…

Oct 1, 2025 · 1 share · 449 followers View post →
NEJM.org
@nejm.org · Bluesky

DIGIT-HF phase 4 trial: In patients with heart failure and reduced ejection fraction, the efficacy of cardiac glycosides when added to contemporary therapies is unclear. Research findings on the safety and efficacy of digitoxin are summarized in a new Quick Take video. nej.md/3IgL4wO

Oct 1, 2025 · 2 likes View post →
Mohammad Keykhaei, MD, MPH
@m_keykhaei · X

RT @drbennisahmed: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction Treatment with digitoxin led to a lower combined…

Sep 30, 2025 · 1 share · 2,014 followers View post →
Jeremy S. Pollock
@bmorecardiology · X

So now what? should we start adding digoxin to our pillars of therapy for HFrEF? https://t.co/xlxge3DkD2 @NEJM @gcfmd @HFSA @drjohnm

Sep 30, 2025 · 8 likes · 1 share · 1,625 followers View post →
Takuya Kishi @ねこ好き循環器内科医
@tkishi_cardiol · X

RT @yumino_medical: 【DrゆみのWeekly Journal Scan】 *収縮機能低下した心不全患者へのジギトキシンの効果 from NEJM* https://t.co/CqvspXj0nE DIGIT-HF試験は、標準治療下におけるジギトキシンの有効性…

Sep 30, 2025 · 1 share · 14,701 followers View post →
医療法人社団ゆみの
@yumino_medical · X

【DrゆみのWeekly Journal Scan】 *収縮機能低下した心不全患者へのジギトキシンの効果 from NEJM* https://t.co/CqvspXj0nE DIGIT-HF試験は、標準治療下におけるジギトキシンの有効性を検証した無作為化二重盲検試験。対象は心不全(HFrEF)患者1212例(LVEF≤40%かつNYHA

Sep 30, 2025 · 7 likes · 1 share · 1,241 followers View post →
Ahmed Bennis MD
@drbennisahmed · X

Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction Treatment with digitoxin led to a lower combined risk of death from any cause or hospital admission for worsening heart failure than placebo among patients with heart failure and reduced ejection fraction who https://t.co/wQwqtM2GEK

Sep 30, 2025 · 10 likes · 1 share · 2,695 followers View post →
東北大学 循環器内科
@cardio_tu · X

2 min cardiology(臨床、担当:千葉直貴) Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction U Bavendiek et al. NEJM Aug 29, 2025 https://t.co/dgZRZf0vrv →

Sep 30, 2025 · 1 like · 1,321 followers View post →
Blessing Muponda
@BMuponda · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 29, 2025 · 32 shares · 101 followers View post →
Pascal Meier,MD
@DrPascalMeier · X

RT @DrPascalMeier: In HFrEF patients on guideline-directed therapy, digitoxin reduced death or HF hospitalization vs placebo. DIGIT-HF (Pha…

Sep 29, 2025 · 1 share · 110,814 followers View post →
Julian P Villacastin
@jvillacastin · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 29, 2025 · 32 shares · 23,327 followers View post →
Odokonyero, MD
@Odokonyero10 · X

RT @rkalyes1: ✍️ Digitoxin (not digoxin this time) still has a roll in HFrEF but you must keep that dose low! ✍️Digitoxin in Patients with…

Sep 29, 2025 · 9 shares · 263 followers View post →
SØÝÈKWØ
@SCHESANGKEN · X

RT @rkalyes1: ✍️ Digitoxin (not digoxin this time) still has a roll in HFrEF but you must keep that dose low! ✍️Digitoxin in Patients with…

Sep 28, 2025 · 9 shares · 633 followers View post →
Michele Emdin
@MicheleEmdin · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 28, 2025 · 32 shares · 1,016 followers View post →
Dr. med. Logan James Yilmaz
@med_yilmaz · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 28, 2025 · 32 shares · 93 followers View post →
Dr. Michael Alexander
@MichaelAlexandp · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 28, 2025 · 32 shares · 843 followers View post →
Pascal Meier,MD
@DrPascalMeier · X

In HFrEF patients on guideline-directed therapy, digitoxin reduced death or HF hospitalization vs placebo. DIGIT-HF (Phase 4, n=1212) now published in @NEJM Another old drug showing new value.

Sep 28, 2025 · 5 likes · 1 share · 110,814 followers View post →
NEJM.org
@nejm.org · Bluesky

In patients with heart failure and reduced ejection fraction who were receiving guideline-directed medical therapy, digitoxin lowered the risk of death or hospitalization for heart failure as compared with placebo. Full DIGIT-HF phase 4 trial results and Research Summary: nej.md/3HQHLfj

Sep 28, 2025 · 9 likes · 1 share View post →
ChefKarim02
@ChefKarim02 · X

RT @rkalyes1: ✍️ Digitoxin (not digoxin this time) still has a roll in HFrEF but you must keep that dose low! ✍️Digitoxin in Patients with…

Sep 28, 2025 · 9 shares · 1,806 followers View post →
Dr J NELSON OKEMA, MD
@DrJNELLY95 · X

RT @rkalyes1: ✍️ Digitoxin (not digoxin this time) still has a roll in HFrEF but you must keep that dose low! ✍️Digitoxin in Patients with…

Sep 28, 2025 · 9 shares · 1,984 followers View post →
VICTOR AINEBYOONA
@victorAinebyona · X

RT @rkalyes1: ✍️ Digitoxin (not digoxin this time) still has a roll in HFrEF but you must keep that dose low! ✍️Digitoxin in Patients with…

Sep 28, 2025 · 9 shares · 1,748 followers View post →
Arcadian Vybz♉
@gabomwe · X

RT @rkalyes1: ✍️ Digitoxin (not digoxin this time) still has a roll in HFrEF but you must keep that dose low! ✍️Digitoxin in Patients with…

Sep 28, 2025 · 9 shares · 1,444 followers View post →
Mohammad Elidy
@elidyynwa · X

RT @rkalyes1: ✍️ Digitoxin (not digoxin this time) still has a roll in HFrEF but you must keep that dose low! ✍️Digitoxin in Patients with…

Sep 28, 2025 · 9 shares · 624 followers View post →
Abdul M. Ssekandi, MBChB, MSc., M.A.P.S
@JC_by_AMS · X

RT @rkalyes1: ✍️ Digitoxin (not digoxin this time) still has a roll in HFrEF but you must keep that dose low! ✍️Digitoxin in Patients with…

Sep 28, 2025 · 9 shares · 1,170 followers View post →
Dr. Oriba Dan Langoya
@DrOribaDan · X

RT @rkalyes1: ✍️ Digitoxin (not digoxin this time) still has a roll in HFrEF but you must keep that dose low! ✍️Digitoxin in Patients with…

Sep 28, 2025 · 9 shares · 23,010 followers View post →
Robert Kalyesubula,MD, FISN(USA), PhD-FRCP(London)
@rkalyes1 · X

✍️ Digitoxin (not digoxin this time) still has a roll in HFrEF but you must keep that dose low! ✍️Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction | New England Journal of Medicine @ChefKarim02 @DrOribaDan @DrJNELLY95 https://t.co/Dlv3aEO5Ap?

Sep 28, 2025 · 33 likes · 9 shares · 18,867 followers View post →
Mark
@headass_deadass · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 27, 2025 · 32 shares · 769 followers View post →
Dr.Dipak Agrawal
@drdiagrawal · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 27, 2025 · 32 shares · 67 followers View post →
Dr.Ezhil Mugunthan
@Ezhil_mugunthan · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 27, 2025 · 32 shares · 57 followers View post →
薬剤師×陶芸 ハシモト
@hayakuhantou · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 27, 2025 · 32 shares · 243 followers View post →
Sac-a:lait
@SAC_A_LAIT · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 27, 2025 · 32 shares · 396 followers View post →
PAT latimer brock
@BrockLatimer · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 27, 2025 · 32 shares · 537 followers View post →
Sandeep Gautam
@gautamsand · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 27, 2025 · 32 shares · 4,402 followers View post →
Pedro Graziano Sanchez
@wikimagen · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 27, 2025 · 32 shares · 7,149 followers View post →
我闯入猫的城镇
@scarlett_viven · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 27, 2025 · 32 shares · 53 followers View post →
Umair Khalid
@Umair2017 · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 27, 2025 · 32 shares · 4,009 followers View post →
Dr.AMiT JAiSWAL
@aadvikmedics · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 27, 2025 · 32 shares · 55 followers View post →
Abdelhamid Hamdy
@abdelhamed012 · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 27, 2025 · 32 shares · 3,356 followers View post →
jabar
@turilrh · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 27, 2025 · 32 shares · 1,464 followers View post →
AngryPhDstudent❗️❗️❗️
@ONNESHA092 · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 27, 2025 · 32 shares · 183 followers View post →
MYATHUZAR
@MYATHUZAR11 · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 27, 2025 · 32 shares · 369 followers View post →
mrspotechi
@mrspotechi77 · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 27, 2025 · 32 shares · 1 followers View post →
darcy darnoc
@darcydarnoc · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 27, 2025 · 32 shares · 3,142 followers View post →
Mohammad Aleidi
@aleidimed · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 27, 2025 · 32 shares · 308 followers View post →
Mark Anderson
@delanceydaily · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 26, 2025 · 32 shares · 2,005 followers View post →
John P Erwin III MD MBA MACC (#BigPoppy )
@HeartOTXHeartMD · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 26, 2025 · 32 shares · 39,651 followers View post →
Dr. Shashank Joshi
@AskDrShashank · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 26, 2025 · 32 shares · 32,513 followers View post →
Herbs and Havoc
@HerbsAndHavoc · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 26, 2025 · 32 shares · 324 followers View post →
Wimen
@1a31551c566e43d · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 26, 2025 · 32 shares · 670 followers View post →
Jose Daniel Mosquera Lozano
@jdmosqueral · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 26, 2025 · 32 shares · 233 followers View post →
MedEd Global Solutions
@global_meded · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 26, 2025 · 32 shares · 247 followers View post →
NEJM
@NEJM · X

Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8mpwOpVo7U Editorial: Digitoxin — A Reminder for Digoxin https://t.co/oBEX3T6z8s #Cardiology https://t.co/RsSBar1xpL

Sep 26, 2025 · 117 likes · 32 shares · 935,883 followers View post →
Truthoverdishonesty
@Nigelj08223326 · X

Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction @NEJM https://t.co/3CJBZii1L9 treatment with digitoxin led to a

Sep 26, 2025 · 1 like · 1,607 followers View post →
Wei-Guo Ma, MD
@Dr_Ma_of_PUMC · X

RT @NEJM: New in the September 25, 2025, issue of NEJM: Digitoxin in Heart Failure with Reduced EF (DIGIT-HF phase 4 trial) https://t.co…

Sep 26, 2025 · 7 shares · 2,370 followers View post →
enigma4ever
@watergatesummer · X

RT @NEJM: New in the September 25, 2025, issue of NEJM: Digitoxin in Heart Failure with Reduced EF (DIGIT-HF phase 4 trial) https://t.co…

Sep 26, 2025 · 7 shares · 8,080 followers View post →
Eugenio Cingolani, MD
@EugenioCingolan · X

Déjà vu ! Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction | New England Journal of Medicine https://t.co/vv61muTISN

Sep 26, 2025 · 1 like · 3,354 followers View post →
Ham (BMI 26)
@dokinoe · X

RT @NEJM: New in the September 25, 2025, issue of NEJM: Digitoxin in Heart Failure with Reduced EF (DIGIT-HF phase 4 trial) https://t.co…

Sep 25, 2025 · 7 shares · 252 followers View post →
旅人 tabito
@tabibito250 · X

Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction | New England Journal of Medicine https://t.co/3BhbmmLnP2

Sep 25, 2025 · 1,073 followers View post →
5Jtas
@5_juntas · X

RT @Carcos2: "El tratamiento con digitoxina⬇️el riesgo de muerte por cualquier causa o ingreso hospitalario por agravamiento de la IC vs.…

Sep 25, 2025 · 1 share · 6 followers View post →
Mark Anderson
@delanceydaily · X

RT @NEJM: New in the September 25, 2025, issue of NEJM: Digitoxin in Heart Failure with Reduced EF (DIGIT-HF phase 4 trial) https://t.co…

Sep 25, 2025 · 7 shares · 2,005 followers View post →
Anum Gull
@Dranumgull · X

RT @NEJM: New in the September 25, 2025, issue of NEJM: Digitoxin in Heart Failure with Reduced EF (DIGIT-HF phase 4 trial) https://t.co…

Sep 25, 2025 · 7 shares · 91 followers View post →
NEJM
@NEJM · X

New in the September 25, 2025, issue of NEJM: Digitoxin in Heart Failure with Reduced EF (DIGIT-HF phase 4 trial) https://t.co/8mpwOpVo7U Apixaban for Provoked Venous Thromboembolism (HI-PRO trial) https://t.co/Epe4Q957pV Measurable Residual Disease–Guided Therapy for CLL https://t.co/8e5qUOXjY6

Sep 25, 2025 · 36 likes · 7 shares · 935,883 followers View post →
Shinya Goto
@sgoto4 · X

RT @sgoto4: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction | New England Journal of Medicine https://t.co/JqLgVDV0W…

Sep 25, 2025 · 2 shares · 322 followers View post →
抗血栓療法
@antithrombosis · X

RT @sgoto4: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction | New England Journal of Medicine https://t.co/JqLgVDV0W…

Sep 25, 2025 · 2 shares · 131 followers View post →
Parmariu17
@parmariu17 · X

Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction | New England Journal of Medicine https://t.co/JP4v7OArYC

Sep 25, 2025 · 102 followers View post →
Carlos Coscollar
@Carcos2 · X

"El tratamiento con digitoxina⬇️el riesgo de muerte por cualquier causa o ingreso hospitalario por agravamiento de la IC vs. placebo en pacientes con IC y⬇️FE que recibieron tto médico según las guías" No ganamos para sorpresas. Digitoxina, no digoxina https://t.co/OFbyhoynz9

Sep 25, 2025 · 1 like · 1 share · 1,144 followers View post →
Shinya Goto
@sgoto4 · X

Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction | New England Journal of Medicine https://t.co/JqLgVDV0WN 歴史的ジギタリスにはHFrEFの予後改善効果があるね!

Sep 24, 2025 · 3 likes · 2 shares · 322 followers View post →
Takuya Kishi @ねこ好き循環器内科医
@tkishi_cardiol · X

RT @Susumu_Manabe: ガイドライン推奨薬を使用している低心機能、心不全患者に、 ジゴキシンを加えることで、総死亡、心不全入院が低下傾向となり、複合エンドポイントは有意に低下。1,240例を対象にした無作為化比較試験https://t.co/R4IVpTibZR

Sep 24, 2025 · 1 share · 14,701 followers View post →
真鍋晋@心臓外科医
@Susumu_Manabe · X

ガイドライン推奨薬を使用している低心機能、心不全患者に、 ジゴキシンを加えることで、総死亡、心不全入院が低下傾向となり、複合エンドポイントは有意に低下。1,240例を対象にした無作為化比較試験https://t.co/R4IVpTibZR

Sep 24, 2025 · 25 likes · 1 share · 2,326 followers View post →
HealthBook
@HealthBook7 · X

RT @drbennisahmed: DIGIT-HF: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction #esccongress #WCCardio #CardioED #MedE…

Sep 24, 2025 · 35 shares · 20 followers View post →
トンヌラ
@37phoenix · X

標準治療が行われているHFrEF患者に対してジギトキシンは全死亡、心不全による入院の複合アウトカムが少なかった(HR0.82).DIGIT-HF trial. N Engl J Med. PMID: 40879493.https://t.co/oDDRgZdiJp

Sep 17, 2025 · 1 like · 2,053 followers View post →
Almansour
@malmansour81 · X

RT @drbennisahmed: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction Treatment with digitoxin led to a lower combined…

Sep 16, 2025 · 1 share · 211 followers View post →
Awatif Hafiz , PharmD , BCCP
@awatifhafiz · X

RT @accpcardprn: #WNW Gotta talk about DIGIT-HF. In pts with HFrEF (EF ~29%, 67% class III) on GDMT (though <20% were on SGLT2i), adding di…

Sep 15, 2025 · 3 shares · 413 followers View post →
Ahmed Bennis MD
@drbennisahmed · X

Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction Treatment with digitoxin led to a lower combined risk of death from any cause or hospital admission for worsening heart failure than placebo among patients with heart failure and reduced ejection fraction who https://t.co/2krqDmmRis

Sep 15, 2025 · 6 likes · 1 share · 2,695 followers View post →
Aurora Conti Gimignano
@AGimignano · X

RT @Derek_Leong_RPh: DIGIT-HF trial: In Pts with HFrEF, NYHA II-IV, on contemporary GDMT, digitoxin (dosed to target level 10.5-23.6 nmol/L…

Sep 13, 2025 · 1 share · 190 followers View post →
Derek Leong
@Derek_Leong_RPh · X

DIGIT-HF trial: In Pts with HFrEF, NYHA II-IV, on contemporary GDMT, digitoxin (dosed to target level 10.5-23.6 nmol/L) ⬇️ all-cause mortality/HF hospitalization vs. placebo (ARR 4.6% at 36 months). https://t.co/0A9RGayz7w https://t.co/zYVsFp5NY0

Sep 13, 2025 · 3 likes · 1 share · 1,562 followers View post →
JiaLiu
@kuldipchavda4 · X

RT @ChuckGartland1: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction | New England Journal of Medicine https://t.co/S…

Sep 11, 2025 · 1 share · 126 followers View post →
Satoru Mitsuboshi
@3stars67664378 · X

RT @pinacol: 【RCT】LVEF40%以下でNYHA分類IIIまたはIV、もしくはLVEF30%以下でNYHA分類IIの慢性心不全患者へのジギトキシンの投与は、プラセボの投与と比較して、全原因死亡、心不全悪化による入院の複合転帰を減少させた。 #ペ読 https:/…

Sep 11, 2025 · 1 share · 1,783 followers View post →
Laura Andino, PharmD, MPH
@Andinogliflozin · X

RT @accpcardprn: #WNW Gotta talk about DIGIT-HF. In pts with HFrEF (EF ~29%, 67% class III) on GDMT (though <20% were on SGLT2i), adding di…

Sep 10, 2025 · 3 shares · 185 followers View post →
Arden Barry
@ArdenBarry · X

RT @accpcardprn: #WNW Gotta talk about DIGIT-HF. In pts with HFrEF (EF ~29%, 67% class III) on GDMT (though <20% were on SGLT2i), adding di…

Sep 10, 2025 · 3 shares · 2,004 followers View post →
ACCP Cardiology PRN
@accpcardprn · X

#WNW Gotta talk about DIGIT-HF. In pts with HFrEF (EF ~29%, 67% class III) on GDMT (though <20% were on SGLT2i), adding digitoxin vs placebo lowered risk of all-cause death or 1st HFH (39.5% vs 44.1%) over 36 months. https://t.co/JHRx2mWr1E

Sep 10, 2025 · 17 likes · 3 shares · 9,295 followers View post →
Chuck Gartland
@ChuckGartland1 · X

Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction | New England Journal of Medicine https://t.co/S4gA23ASEU DIGITOXIN is not digoxin. I know because Dr. Eby made us memorize the similarities and differences in Pharmacognosy class Temple Pharm.

Sep 10, 2025 · 2 likes · 1 share · 1,466 followers View post →
rmohty
@rmohty · X

RT @AnilMakam: 3| DIGIT-HF Is GDMT for HF coming full circle? In a double-blind multicenter trial of advanced HFrEF, digitoxin—a safer di…

Sep 8, 2025 · 1 share · 613 followers View post →
Anil Makam
@AnilMakam · X

3| DIGIT-HF Is GDMT for HF coming full circle? In a double-blind multicenter trial of advanced HFrEF, digitoxin—a safer digoxin analog not available in the US—reduced mortality & hospitalizations A Dutch trial of digoxin is underway! https://t.co/n4pHqKdy2S

Sep 8, 2025 · 14 likes · 1 share · 6,847 followers View post →
AngryPhDstudent❗️❗️❗️
@ONNESHA092 · X

RT @drbennisahmed: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction Treatment with digitoxin led to a lower combined…

Sep 7, 2025 · 3 shares · 183 followers View post →
pinacol
@pinacol · X

【RCT】LVEF40%以下でNYHA分類IIIまたはIV、もしくはLVEF30%以下でNYHA分類IIの慢性心不全患者へのジギトキシンの投与は、プラセボの投与と比較して、全原因死亡、心不全悪化による入院の複合転帰を減少させた。 #ペ読 https://t.co/U1bLKLAod9

Sep 7, 2025 · 4 likes · 1 share · 1,615 followers View post →
Philipp Lopatka
@LopatkaPhilipp · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Sep 7, 2025 · 48 shares · 198 followers View post →
Dr. Omar
@DrOmarkhalil · X

RT @mzkhalil: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction | NEJM #ESCCongress Okay for Digitoxin in HFrEF… bu…

Sep 6, 2025 · 4 shares · 378 followers View post →
Dr.Rajiv Sankaranarayanan
@DrRajivsankar · X

RT @drbennisahmed: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction Treatment with digitoxin led to a lower combined…

Sep 6, 2025 · 3 shares · 3,983 followers View post →
Shelley Zieroth
@ShelleyZieroth · X

RT @drbennisahmed: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction Treatment with digitoxin led to a lower combined…

Sep 6, 2025 · 3 shares · 10,003 followers View post →
Ahmed Bennis MD
@drbennisahmed · X

Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction Treatment with digitoxin led to a lower combined risk of death from any cause or hospital admission for worsening heart failure than placebo among patients with heart failure and reduced ejection fraction who https://t.co/36ere8hcsl

Sep 6, 2025 · 17 likes · 3 shares · 2,695 followers View post →
Grupo Cardio SEFH
@cardio_sefh · X

Y si quieres leer el ensayo completo, este es el link: https://t.co/MWwqJ5wlkA ➡️3-year follow-up: primary outcome event of all-cause death or first hospitalization for #heartfailure occurred in 39.5% of patients in the #digitoxin group vs 44.1% placebo. RAR=4,6% (NNT=22) #HFrEF https://t.co/Wa8KTTBMDL

Sep 6, 2025 · 119 followers View post →
Diegos holguines
@Diegoho32788292 · X

RT @ffaviles: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction | New England Journal of Medicine https://t.co/h553faz…

Sep 4, 2025 · 1 share · 210 followers View post →
David GGlez
@DavidGGlezFarm · X

RT @BITNavarra: Digitoxina en pacientes con insuficiencia cardiaca y fracción de eyección reducida

Sep 4, 2025 · 2 shares · 139 followers View post →
Hany Ragy
@Hragy · X

RT @drraviele: https://t.co/i7IcQao8Oo

Sep 4, 2025 · 1 share · 80,454 followers View post →
Raviele Antonio
@drraviele · X

https://t.co/i7IcQao8Oo

Sep 4, 2025 · 1 like · 1 share · 23,407 followers View post →
Jose Luis Quintana
@JoseLuisQ · X

RT @BITNavarra: Digitoxina en pacientes con insuficiencia cardiaca y fracción de eyección reducida

Sep 4, 2025 · 2 shares · 2,875 followers View post →
BIT Navarra
@BITNavarra · X

Digitoxina en pacientes con insuficiencia cardiaca y fracción de eyección reducida

Sep 4, 2025 · 5 likes · 2 shares · 6,010 followers View post →
Isaura R. Penin
@irodriguezpenin · X

Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction | New England Journal of Medicine https://t.co/3PeYXCNwDZ

Sep 4, 2025 · 623 followers View post →
Bryan Cotton
@bryanacotton1 · X

Dig again for the win. In pts with HF and ⬇️ E.F, digitoxin led to ⬇️ ☠️ from any cause or hospitalization for worsening HF compared to placebo. Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction | New England Journal of Medicine https://t.co/PPZcx2JCSB

Sep 4, 2025 · 6 likes · 5,038 followers View post →
南郷 栄秀/Eishu NANGO, MD, PhD
@enango · X

HFrEF患者1240人を対象とした国際RCT(DIGIT-HF)では,digitoxinはプラセボより総死亡または心不全増悪入院を減らした(39.5%対44.1%,HR 0.82,0.69~0.98).総死亡(HR 0.86)や入院(HR 0.85)は単独では有意に減らなかった. https://t.co/k9JX8MsCxL

Sep 3, 2025 · 3,018 followers View post →
Naomi Niznick, MD FRCPC
@NaomiNiznick · X

https://t.co/XgHBo21Jqr ❤️ #digoxin

Sep 3, 2025 · 2 likes · 434 followers View post →
Jaime Larre Guerra
@jalarreg97 · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 3, 2025 · 50 shares · 90 followers View post →
Miguel Angel Samaniego
@MiguelSama1007 · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Sep 3, 2025 · 48 shares · 26 followers View post →
Jeremy S. Pollock
@bmorecardiology · X

Can we get Digitoxin in the USA? Not sure I would use digoxin from these results.. although compelling.. https://t.co/xlxge3DkD2 #DIGITHF @NEJM @gcfmd @HFSA @drjohnm

Sep 2, 2025 · 1,625 followers View post →
Blanca A Serrano Moreno
@BlancaASer34709 · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Sep 2, 2025 · 48 shares · 16 followers View post →
Tom Hsiung
@TomHsiung · X

Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction | New England Journal of Medicine https://t.co/L6tXYLtZgd

Sep 2, 2025 · 463 followers View post →
Dr. Milton Milton Montaño H. Cardiólogo
@Genio20cardio · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Sep 2, 2025 · 48 shares · 1,077 followers View post →
Gabriel Largaespada Pérez
@largaesEP · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Sep 2, 2025 · 48 shares · 162 followers View post →
抗血栓療法
@antithrombosis · X

RT @antithrombosis: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction | New England Journal of Medicine https://t.co/a…

Sep 2, 2025 · 1 share · 131 followers View post →
抗血栓療法
@antithrombosis · X

Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction | New England Journal of Medicine https://t.co/aDVQVZMA3W ジギタリス、意外によかったね!驚きでした!

Sep 1, 2025 · 2 likes · 1 share · 131 followers View post →
Marcio Leite Rodrigues
@Marcio_Cardio · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Sep 1, 2025 · 48 shares · 41 followers View post →
Gabriela GuzmánCleto
@GabyGuzmanCleto · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Sep 1, 2025 · 48 shares · 216 followers View post →
Dr Ronak Javia
@RonakJavia27 · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Sep 1, 2025 · 48 shares · 269 followers View post →
Vladyslav Kavalerchyk
@echo_stepbystep · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Sep 1, 2025 · 48 shares · 18,155 followers View post →
Will Watson
@DrWillWatson · X

Catching up on the ESC (I was away... more later) and excited to read the Digit-HF study and @drjohnm 's digest of it. Cardiac glycosides do have a role in HFrEF, with digitoxin additive to contemporary HF management in reducing death/hospitalisation https://t.co/bw3HBPN3EN

Sep 1, 2025 · 3 likes · 3,325 followers View post →
Daniel Barrera M
@dabarreram · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Sep 1, 2025 · 48 shares · 152 followers View post →
Syed Shahrul Naz
@drshahrul80 · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Sep 1, 2025 · 48 shares · 6,927 followers View post →
☫кептагоп™Я☫
@kentaron1971 · X

今日実習生に教えたこと

Sep 1, 2025 · 2 likes · 12,442 followers View post →
Abdallah Al-Mohammad
@AAlMohammad87 · X

A fantastic finding #DIGIT_HF trial @NEJM adding #Digitoxin to #GDMT for #HFrEF reduces all cause mortality + HFHospitalisation @BSHeartFailure @BritishCardioSo @SheffieldHosp @sheffielduni #CardioTwitter @TheresaMcDonag3 https://t.co/eeJFpoeQzA

Sep 1, 2025 · 930 followers View post →
Jaymin S Shah
@JayminSShah1 · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Sep 1, 2025 · 48 shares · 260 followers View post →
Suriya Prausmüller
@prausmuller · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Sep 1, 2025 · 50 shares · 28 followers View post →
N
@NCKAR1999 · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Sep 1, 2025 · 48 shares · 14 followers View post →
Shankaragouda B H, DM FSCAI
@sbh0012 · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Sep 1, 2025 · 48 shares · 91 followers View post →
Paul Ξlung'ata®, RN
@PElungata · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Aug 31, 2025 · 48 shares · 588 followers View post →
Leejiasheng
@jiashenglee · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Aug 31, 2025 · 48 shares · 21 followers View post →
EOLO MORANDI JR.
@eolojr · X

RT @mzkhalil: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction | NEJM #ESCCongress Okay for Digitoxin in HFrEF… bu…

Aug 31, 2025 · 4 shares · 539 followers View post →
Mario092
@Mario0921170302 · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Aug 31, 2025 · 48 shares · 3 followers View post →
Aaysha Cader
@aayshacader · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Aug 31, 2025 · 48 shares · 9,067 followers View post →
Ganesan
@ganesh48205798 · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Aug 31, 2025 · 48 shares · 35 followers View post →
Sirin Auepojjanasirin
@auepojjanasirin · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Aug 31, 2025 · 48 shares · 148 followers View post →
Natsir Ramadhan
@natsiradhan · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Aug 31, 2025 · 48 shares · 562 followers View post →
TEE Fan
@TEE_Fan · X

RT @mzkhalil: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction | NEJM #ESCCongress Okay for Digitoxin in HFrEF… bu…

Aug 31, 2025 · 4 shares · 620 followers View post →
Mehmet K. Aktaş MD, MBA
@mkaktas · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Aug 31, 2025 · 48 shares · 161 followers View post →
El6Pollo
@El6Pollo · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Aug 31, 2025 · 50 shares · 47 followers View post →
Deni Setiawan Anggai
@anotherdeni · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Aug 31, 2025 · 48 shares · 83 followers View post →
AngryPhDstudent❗️❗️❗️
@ONNESHA092 · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Aug 31, 2025 · 48 shares · 183 followers View post →
SrivatsaNagachandan
@Srivatsa34 · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Aug 31, 2025 · 48 shares · 2,249 followers View post →
Bhuwan Thapa, MD
@Drthapa12 · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Aug 31, 2025 · 48 shares · 35 followers View post →
Karl Dujardin
@KDujardin · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Aug 31, 2025 · 48 shares · 644 followers View post →
Agbadaola Seun
@AgbadaolaSeun · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Aug 31, 2025 · 48 shares · 339 followers View post →
Onofre Casas Castro
@onofre_casas · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Aug 31, 2025 · 48 shares · 109 followers View post →
Mark Luedde
@LuddeMark · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Aug 31, 2025 · 48 shares · 233 followers View post →
Fungiydad
@fungiydad · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Aug 31, 2025 · 48 shares · 118 followers View post →
BiigNaJaa
@BiigNaJaa · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Aug 31, 2025 · 48 shares · 529 followers View post →
Mohammad Aleidi
@aleidimed · X

RT @DrDamluji: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction: @NEJM

Aug 31, 2025 · 48 shares · 308 followers View post →
Gabi LS
@erudainthur · X

RT @FormigaFrancesc: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction | New England Journal of Medicine https://t.co/…

Aug 31, 2025 · 4 shares · 50 followers View post →
Dr.Vaibhav Triapthi MD
@DrVaibhav1992 · X

RT @mzkhalil: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction | NEJM #ESCCongress Okay for Digitoxin in HFrEF… bu…

Aug 31, 2025 · 4 shares · 190 followers View post →
Professor M Z Khalil
@mzkhalil · X

Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction | NEJM #ESCCongress Okay for Digitoxin in HFrEF… but wait  The only available ARNI is sacubitril/valsartan (ARNI+ARB) yet they manage to recruit 40% ARNI & 18% ARB..!! Analyze

Aug 31, 2025 · 11 likes · 4 shares · 2,856 followers View post →
Oscar Cingolani, MD
@cingolani_oscar · X

Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction | New England Journal of Medicine https://t.co/56reWx7nhc

Aug 30, 2025 · 1 like · 27,646 followers View post →
【公式】自治医科大学附属さいたま医療センター 麻酔科・集中治療部
@jichisaitamaicu · X

HFpEFへのジゴキシン、composite(死亡+初回心不全入院)改善。サブグループはEF<30や血圧低下に特に有効。KMが3ヶ月で重なるのが気になります https://t.co/eyYrWS0bCP ランドマークのDIG試験は二重盲検してなく、そこから数十年あいていた。予定より少なく終了しており、現在走ってるRCTに期待です https://t.co/VUhVG1mAqJ

Aug 30, 2025 · 5 likes · 2,624 followers View post →
Dr. Sou
@SwissHeartDoc · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Aug 30, 2025 · 50 shares · 884 followers View post →
Jean francis MD,FASN
@jeanfrancis72 · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Aug 30, 2025 · 50 shares · 557 followers View post →
strawberry
@strawberry88122 · X

RT @medical_xpress: Digitoxin, derived from red foxglove, significantly reduces mortality and hospitalizations in patients with advanced HF…

Aug 30, 2025 · 15 shares · 1,090 followers View post →
Z Rana
@Dr_ZRana · X

Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction | New England Journal of Medicine. Revisiting a classic. Results: very surprising! https://t.co/J8r1tH7OOz

Aug 30, 2025 · 21 followers View post →
Ashish Aneja MD FACC FAHA FASE FSCMR
@ash71us · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Aug 30, 2025 · 50 shares · 4,932 followers View post →
Ahmed K. Mahmoud
@AhmedMahmoud_MD · X

DIGIT-HF trial An old drug might be added to GDMT?! The study drug was digitoxin—not digoxin. They’re different molecular profiles. When HF hospitalisations were analysed alone, there was no improvement. Waiting for Digoxin trial “DECISION trial” https://t.co/9jZjwOqS2H

Aug 30, 2025 · 4 likes · 893 followers View post →
Antonella degani
@Antonelladegan3 · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Aug 30, 2025 · 50 shares · 757 followers View post →
Powell Kafwanka, MBChB, MSc
@PowellKafwanka · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Aug 30, 2025 · 50 shares · 93 followers View post →
RONAK GANDHI
@drronakmgandhi · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Aug 30, 2025 · 50 shares · 260 followers View post →
Neo_ID เป็นพ่อมดสัตว์จิ๋ว
@1IDCNMI · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Aug 30, 2025 · 50 shares · 29,168 followers View post →
Javier Gomez-Valencia MD
@InkedHeartDoc · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Aug 30, 2025 · 50 shares · 540 followers View post →
Lorenzo Fácila
@mi_cardiologo · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Aug 30, 2025 · 50 shares · 7,939 followers View post →
Lilia
@Cookie_2025521 · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Aug 30, 2025 · 50 shares · 209 followers View post →
John P Erwin III MD MBA MACC (#BigPoppy )
@HeartOTXHeartMD · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Aug 30, 2025 · 50 shares · 39,651 followers View post →
EOLO MORANDI JR.
@eolojr · X

RT @FormigaFrancesc: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction | New England Journal of Medicine https://t.co/…

Aug 30, 2025 · 4 shares · 539 followers View post →
Reza Ghanavati, MD.
@Ghanavati_r · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Aug 30, 2025 · 50 shares · 326 followers View post →
Zorba Blázquez Bermejo
@ZorbaBlazquez · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Aug 30, 2025 · 50 shares · 1,142 followers View post →
Dr Stephen T Webb
@stephen_t_webb · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Aug 30, 2025 · 50 shares · 8,543 followers View post →
Jose Rivas Rios, MD, FACC, FNLA
@joshep_r · X

RT @NEJM: Original Article: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF phase 4 trial) https://t.co/8m…

Aug 30, 2025 · 50 shares · 351 followers View post →
serrgv
@serrgv · X

RT @medical_xpress: Digitoxin, derived from red foxglove, significantly reduces mortality and hospitalizations in patients with advanced HF…

Aug 30, 2025 · 15 shares · 147 followers View post →
Rene Sugar
@renesugar · X

RT @medical_xpress: Digitoxin, derived from red foxglove, significantly reduces mortality and hospitalizations in patients with advanced HF…

Aug 30, 2025 · 15 shares · 3,971 followers View post →
Luis Alberto Luengo
@luengo1958 · X

RT @medical_xpress: Digitoxin, derived from red foxglove, significantly reduces mortality and hospitalizations in patients with advanced HF…

Aug 30, 2025 · 15 shares · 17,812 followers View post →
NP AGARWAL世界一フォローを目指しますAiming best in world.
@np_grwl · X

RT @medical_xpress: Digitoxin, derived from red foxglove, significantly reduces mortality and hospitalizations in patients with advanced HF…

Aug 30, 2025 · 15 shares · 1,786 followers View post →
Natugardener
@natugardener · X

RT @medical_xpress: Digitoxin, derived from red foxglove, significantly reduces mortality and hospitalizations in patients with advanced HF…

Aug 30, 2025 · 15 shares · 1,518 followers View post →
Ordo Fraterna Fibonacci
@ordofibonacci.bsky.social · Bluesky

Hot Line 1 – DIGIT-HF: Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction European Society of Cardiology youtu.be/dd6dF81KyhE?...

Aug 30, 2025 View post →
Tim Hulse
@timhulse · X

RT @medical_xpress: Digitoxin, derived from red foxglove, significantly reduces mortality and hospitalizations in patients with advanced HF…

Aug 29, 2025 · 15 shares · 553 followers View post →
syawal™ シ
@syawal · X

RT @medical_xpress: Digitoxin, derived from red foxglove, significantly reduces mortality and hospitalizations in patients with advanced HF…

Aug 29, 2025 · 15 shares · 3,185 followers View post →
Phys.org
@physorg_com · X

RT @medical_xpress: Digitoxin, derived from red foxglove, significantly reduces mortality and hospitalizations in patients with advanced HF…

Aug 29, 2025 · 15 shares · 1,024,102 followers View post →
Medical Xpress
@medical_xpress · X

Digitoxin, derived from red foxglove, significantly reduces mortality and hospitalizations in patients with advanced HFrEF, offering a safe and cost-effective treatment option—even with kidney impairment. @nejm https://t.co/aF3DT0CEbC https://t.co/4jBRQCe2gm

Aug 29, 2025 · 19 likes · 15 shares · 173,093 followers View post →
BaladoCritique : club de lecture médical
@baladocritique.bsky.social · Bluesky

"Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction." Présenté ce jour à l' #ESCCongress et publié dans le @nejm.org. #MedSky #CardioSky www.nejm.org/doi/full/10....

Aug 29, 2025 · 1 like View post →
NEJM.org
@nejm.org · Bluesky

Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (DIGIT-HF Phase 4 trial) nej.md/3HQHLfj Multidomain Rehabilitation for Older Patients with Myocardial Infarction (PIpELINe trial) nej.md/4fRsuYh

Aug 29, 2025 · 2 likes View post →