The general tone of the discussions indicates strong agreement and interest, with users referencing specific aspects of the research such as genetic targeting and its effect on dementia, using words like 'impressive' and 'significant,' which reflect motivated engagement and acknowledgment of high impact. This collective sentiment underscores the perceived importance of the study's findings for health research.
AgreementStrong agreement
Most discussions strongly support the findings, emphasizing the positive link between lowering cholesterol and dementia risk reduction.
InterestHigh interest
Numerous posts highlight the importance of the study with phrases like 'impressive' and 'significant data,' indicating high engagement and curiosity.
EngagementHigh engagement
Posts reference specific research details, methods, and potential clinical implications, demonstrating deep involvement.
ImpactHigh impact
The tone suggests the findings could influence future medical practices and public health strategies, emphasizing their high relevance.
Top posts
Most liked on X and Bluesky
PS
Prof. Dr. Güner Sönmez
@DrGunerSonmez · X
Yeni Araştırma:
Kolesterol düşürücü ilaçlar, demans riskini azaltabilir.
https://t.co/5Ayt6NtJTn https://t.co/4RGR2mXzZo
Oct 25, 2025 · 194 likes · 14 shares · 512,726 followersView post →
TD
Thomas Dayspring
@Drlipid · X
Good news: except for those who think lowering cholesterol is averse to the brain health - lipid Rx lessens AD risk - https://t.co/aOABkRogrx @nationallipid @society_eas @ASPCardio @escardio @atherosociety @MenopauseOrg @FamilyHeartFdn @fhpatienteurope #dementia https://t.co/nge57FHLDM
Oct 8, 2025 · 142 likes · 32 shares · 44,055 followersView post →
C
Crémieux
@cremieuxrecueil · X
Lower that LDL!
Source: https://t.co/RBGI6cO0nC
Oct 26, 2025 · 46 likes · 281,554 followersView post →
BN
Borge G Nordestgaard
@BNordestgaard · X
Liv T Nordestgaard et al here show that genetic lowering of non-HDL cholesterol via HMGCR, NPC1L1, and
CETP reduces the risk of dementia - just published in Alzheimer's & Dementia:
https://t.co/ovluLKMox3
The totality of data to come to this conclusion is impressive: https://t.co/t6y3w3bdPu
Oct 8, 2025 · 20 likes · 8 shares · 1,604 followersView post →
J
Josh
@JoshJwageman · X
Worlds collide! The eminently venerable Nordestgaards, and the typically provocative topics of Mendelian Randomization, LLT and dementia all in one place! For your awareness: @ApoDudz @JohnKastelein @DrScottMurray @Drlipid @ethanjweiss x
https://t.co/JW0VFdjbRk
Oct 8, 2025 · 18 likes · 5 shares · 377 followersView post →
MX
Medical Xpress
@medical_xpress · X
Lowering blood cholesterol, whether through genetics or medication, is linked to a significantly reduced risk of developing #Dementia, according to analysis of over a million individuals across Europe. @alzassociation https://t.co/KNXLfc0LYc https://t.co/vABxter3Ic
Oct 13, 2025 · 17 likes · 9 shares · 172,874 followersView post →
Does lowering cholesterol reduce dementia risk? This video examines recent studies, clarifies what was actually tested, and explores how metabolic health impacts dementia, highlighting the importance of study context…
This video explores how statins impact cognition, including potential reversible impairment and dementia risk reduction. It discusses conflicting evidence from observational studies and RCTs, emphasizing the importance…
Researchers found that people with genetic traits that mimic the effects of cholesterol-lowering drugs (like statins and ezetimibe) showed up to an 80% lower risk of dementia.
https://t.co/NhPeb10JcP
#Dementia #Alzheimers #Cholesterol #HeartHealth #Genetics #HealthResearch https://t.co/dQpmX9GNu6
Cholesterol-lowering drug targets reduce risk of dementia: Mendelian randomization and meta-analyses of 1 million individuals
https://t.co/fEr5USw92G https://t.co/ABQ9IPrzHW
Oct 24, 2025 · 14 likes · 5 shares · 43,794 followersView post →
RT @Drlipid: Good news: except for those who think lowering cholesterol is averse to the brain health - lipid Rx lessens AD risk - https://…
Oct 15, 2025 · 32 shares · 112 followersView post →
KM
Kate M.
@KateM000000 · X
RT @medical_xpress: Lowering blood cholesterol, whether through genetics or medication, is linked to a significantly reduced risk of develo…
Oct 13, 2025 · 9 shares · 157 followersView post →
MX
Medical Xpress
@medical_xpress · X
Lowering blood cholesterol, whether through genetics or medication, is linked to a significantly reduced risk of developing #Dementia, according to analysis of over a million individuals across Europe. @alzassociation https://t.co/KNXLfc0LYc https://t.co/vABxter3Ic
Oct 13, 2025 · 17 likes · 9 shares · 172,874 followersView post →
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nfkb
@nfkb · X
@woelkchen123456 @nntaleb Cholesterol‐lowering drug targets reduce risk of dementia: Mendelian randomization and meta‐analyses of 1 million individuals - Nordestgaard - 2025 - Alzheimer's & Dementia - Wiley Online Library https://t.co/VFyOnMganh
Oct 13, 2025 · 1 like · 4,009 followersView post →
SB
Simon Hill MSc, BSc
@theproof · X
RT @Drlipid: Good news: except for those who think lowering cholesterol is averse to the brain health - lipid Rx lessens AD risk - https://…
Oct 12, 2025 · 32 shares · 34,363 followersView post →
JS
John Patrick Stein
@JPSwcpmc · X
RT @JoshJwageman: Worlds collide! The eminently venerable Nordestgaards, and the typically provocative topics of Mendelian Randomization,…
Oct 12, 2025 · 5 shares · 554 followersView post →
F
FTM
@followthemotive · X
RT @BNordestgaard: Liv T Nordestgaard et al here show that genetic lowering of non-HDL cholesterol via HMGCR, NPC1L1, and
CETP reduces the…
Oct 11, 2025 · 8 shares · 160 followersView post →
RL
Rx Readmore Livemore
@SopitaSirirata1 · X
RT @BNordestgaard: Liv T Nordestgaard et al here show that genetic lowering of non-HDL cholesterol via HMGCR, NPC1L1, and
CETP reduces the…
Oct 11, 2025 · 8 shares · 181 followersView post →
MM
Marilyn Mann
@MarilynMann · X
RT @BNordestgaard: Liv T Nordestgaard et al here show that genetic lowering of non-HDL cholesterol via HMGCR, NPC1L1, and
CETP reduces the…
Oct 10, 2025 · 8 shares · 2,773 followersView post →
MM
Marilyn Mann
@MarilynMann · X
RT @drjorfer: Cholesterol‐lowering drug targets reduce risk of dementia: Mendelian randomization and meta‐analyses of 1 million individuals…
Oct 10, 2025 · 1 share · 2,773 followersView post →
DM
Dr Scott W Murray
@DrScottMurray · X
RT @JoshJwageman: Worlds collide! The eminently venerable Nordestgaards, and the typically provocative topics of Mendelian Randomization,…
Oct 10, 2025 · 5 shares · 6,160 followersView post →
CB
Christie Ballantyne
@CBallantyneMD · X
RT @JoshJwageman: Worlds collide! The eminently venerable Nordestgaards, and the typically provocative topics of Mendelian Randomization,…
Oct 10, 2025 · 5 shares · 4,774 followersView post →
DK
Dr Meral Kayikcioglu
@MeralKayikcoglu · X
RT @BNordestgaard: Liv T Nordestgaard et al here show that genetic lowering of non-HDL cholesterol via HMGCR, NPC1L1, and
CETP reduces the…
Oct 10, 2025 · 8 shares · 4,363 followersView post →
GD
Gary Deed
@garydeed · X
RT @Drlipid: Good news: except for those who think lowering cholesterol is averse to the brain health - lipid Rx lessens AD risk - https://…
Oct 10, 2025 · 32 shares · 114 followersView post →
RR
Rene Rodriguez
@renecardio4 · X
RT @Drlipid: Good news: except for those who think lowering cholesterol is averse to the brain health - lipid Rx lessens AD risk - https://…
Oct 10, 2025 · 32 shares · 1,168 followersView post →
JF
JORGE FERNANDEZ
@drjorfer · X
Cholesterol‐lowering drug targets reduce risk of dementia: Mendelian randomization and meta‐analyses of 1 million individuals - Nordestgaard - 2025 - Alzheimer's & Dementia - Wiley Online Library
Oct 9, 2025 · 1 share · 1,024 followersView post →
JM
John Maraganore
@JMaraganore · X
RT @Drlipid: Good news: except for those who think lowering cholesterol is averse to the brain health - lipid Rx lessens AD risk - https://…
Oct 9, 2025 · 32 shares · 15,898 followersView post →
RB
Roger Blumenthal
@rblument1 · X
RT @Drlipid: Good news: except for those who think lowering cholesterol is averse to the brain health - lipid Rx lessens AD risk - https://…
Oct 9, 2025 · 32 shares · 8,924 followersView post →
JS
John Patrick Stein
@JPSwcpmc · X
More information that helps clarify the message of safety and benefit. https://t.co/FPdA2eF5tQ
Las personas con predisposición genética a niveles más bajos de colesterol desarrollan menos enf. cardiovasculares y menos demencia. Este estudio sugiere que reducir tus niveles de colesterol pronto en la vida te protegería de demencia después https://t.co/AaE0xFvrnP
RT @Drlipid: Good news: except for those who think lowering cholesterol is averse to the brain health - lipid Rx lessens AD risk - https://…
Oct 8, 2025 · 32 shares · 354 followersView post →
PC
Prof Derek Connolly
@DrDerekConnolly · X
RT @Drlipid: Good news: except for those who think lowering cholesterol is averse to the brain health - lipid Rx lessens AD risk - https://…
Oct 8, 2025 · 32 shares · 3,955 followersView post →
PB
Prof. Dr. Sanjeev Bagai
@BagaiDr · X
Cholesterol‐lowering drug targets⬇️risk of dementia:randomization meta‐analyses of 1 million-2025;Alzheimer's & Dementia.OR/ 1 mmol/L (39 mg/dL) ⬇️ non-HDL-C was 0.24 for HMGCR, 0.18 for NPC1L1, 0.97 for PCSK9, 1.66 for ANGPTL4, 1.41 for LPL, 0.30 for CETP https://t.co/Fba0bc1ZDI
Oct 8, 2025 · 1 share · 34,648 followersView post →
Aب
Abdulmohsen bakhsh د .عبدالمحسن بخش
@amohsenbakhsh · X
@Altebainawi Meta-analysis شمل مليون شخص يؤكد اخبار سارة
باستثناء من يعتقدون ان خفض الكوليسترول يضر بصحة الدماغ فإن الحقيقة انه يقلل من خطر الإصابة بالخرف
https://t.co/YNtsIb3mzK
Oct 8, 2025 · 14 likes · 1 share · 2,041 followersView post →
JH
Juhana Harju
@JuhanaHarju · X
RT @Drlipid: Good news: except for those who think lowering cholesterol is averse to the brain health - lipid Rx lessens AD risk - https://…
Oct 8, 2025 · 32 shares · 1,688 followersView post →
DS
Dr. Luiz Silva
@DrLuizSilva1 · X
RT @Drlipid: Good news: except for those who think lowering cholesterol is averse to the brain health - lipid Rx lessens AD risk - https://…
Oct 8, 2025 · 32 shares · 397 followersView post →
JF
Joel "Heart Prevention" Kahn MD, FACC
@drjkahn · X
RT @Drlipid: Good news: except for those who think lowering cholesterol is averse to the brain health - lipid Rx lessens AD risk - https://…
Oct 8, 2025 · 32 shares · 32,192 followersView post →
HR
Hany Ragy
@Hragy · X
RT @Drlipid: Good news: except for those who think lowering cholesterol is averse to the brain health - lipid Rx lessens AD risk - https://…
Oct 8, 2025 · 32 shares · 80,662 followersView post →
DG
Dr. Robert Glatter
@DrRobertGlatter · X
RT @Drlipid: Good news: except for those who think lowering cholesterol is averse to the brain health - lipid Rx lessens AD risk - https://…
Oct 8, 2025 · 32 shares · 5,909 followersView post →
DP
Dr. Swapneil Parikh
@swapneilparikh · X
RT @Drlipid: Good news: except for those who think lowering cholesterol is averse to the brain health - lipid Rx lessens AD risk - https://…
Oct 8, 2025 · 32 shares · 6,493 followersView post →
TD
Thomas Dayspring
@Drlipid · X
Good news: except for those who think lowering cholesterol is averse to the brain health - lipid Rx lessens AD risk - https://t.co/aOABkRogrx @nationallipid @society_eas @ASPCardio @escardio @atherosociety @MenopauseOrg @FamilyHeartFdn @fhpatienteurope #dementia https://t.co/nge57FHLDM
Oct 8, 2025 · 142 likes · 32 shares · 44,055 followersView post →
J
Josh
@JoshJwageman · X
Worlds collide! The eminently venerable Nordestgaards, and the typically provocative topics of Mendelian Randomization, LLT and dementia all in one place! For your awareness: @ApoDudz @JohnKastelein @DrScottMurray @Drlipid @ethanjweiss x
https://t.co/JW0VFdjbRk
Oct 8, 2025 · 18 likes · 5 shares · 377 followersView post →
BN
Borge G Nordestgaard
@BNordestgaard · X
Liv T Nordestgaard et al here show that genetic lowering of non-HDL cholesterol via HMGCR, NPC1L1, and
CETP reduces the risk of dementia - just published in Alzheimer's & Dementia:
https://t.co/ovluLKMox3
The totality of data to come to this conclusion is impressive: https://t.co/t6y3w3bdPu
Oct 8, 2025 · 20 likes · 8 shares · 1,604 followersView post →
F
**COMBO OF CARDIOVASCULAR DRUGS REDUCE RISK OF ...
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#diabetessuck https://alz-journals.onlinelibrary.wiley. com/doi/10.1002/alz.70638. May be an image of text that says 'ALZHEIMER 피과지 DEMENTIA CARE. Beni ...
2011;70:638-641. 10:3970-3976. 120. Mayorandan S, Meyer U, Hartmann H ... https://doi.org/10.1002/jimd.12223. Benzoate treatment and the glycine index ...
It's Alzheimer's awareness month so I thought it would be a great ...
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MORE ON LOW CHOLESTEROL AND DEMENTIA RISK: A massive ...
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... 10.1002/alz.70638. Log in · MORE ON LOW CHOLESTEROL AND DEMENTIA RISK: ... OCR: ALZHEIMER'S ASSOCIATION Alzheimer's &Dementia® THE JOURNAL OF THE ...