N Engl J Med April 1974 PMID 4816961

Depression of plasma testosterone levels after chronic intensive marihuana use.

R C Kolodny, W H Masters, R M Kolodner, G Toro

Mentions

30
Peak: 4 in Aug 2023
across 4 sources since Apr 2015

Extended reach

761,989
potential audience

Total likes

15,209

Video views

545,076

Mentions per month

Apr 2015 – Sep 2025

Where it's discussed

  • X / Twitter17 posts
  • Reddit8 posts
  • Facebook3 posts
  • YouTube2 videos

AI synopsis

What people are saying

Comments range from dismissive remarks questioning the focus of the research to critical responses about its implications, with some posts sharing references and highlighting the study's relevance, but overall engagement remains shallow and divided in opinion.

AgreementLow agreement

The discussions show mixed opinions, with some dismissing the article or criticizing others' interpretations, indicating slight disagreement overall.

InterestModerate interest

There is moderate interest, as many posts reference the research and include some discussion on its implications, though some are superficial.

EngagementNeutral engagement

Engagement appears neutral; some users briefly comment or criticize, but few delve deeply into scientific details or broader impacts.

ImpactNeutral impact

The discussions do not demonstrate a strong belief in the article's immediate or broad societal impact, with some dismissive or neutral responses.

Abstract in brief

  • The study examines how long-term, intense use of marijuana can lead to a decrease in testosterone levels in the blood.
  • It suggests that chronic marijuana consumption may negatively impact male hormonal balance, potentially affecting reproductive health.
  • The research highlights the importance of understanding the hormonal effects of sustained marijuana use, especially for frequent users.]

Top posts

Most liked on X and Bluesky
Richard Chlad
@jh57496292 · X

@skrblik https://t.co/b3nBHkyrvr

Nov 28, 2024 · 19 likes · 376 followers View post →
Miloslav Šindelář
@Milosval1 · X

Aug 22, 2023 · 16 likes · 16,101 followers View post →
Chirag Barjatya
@chiragbarjatyaa · X

Just like few people take that “high” from lighting weights which provides you Health benefits. REFERENCES 1.Kolodny, R.C., et al., Depression of plasma testosterone levels after chronic intensive marihuana use. 1974. 290(16): p. 872-874.

Dec 8, 2022 · 10 likes · 99,358 followers View post →
Nutrition Detective
@NutriDetect · X

@orlandoacu Paper: Depression of plasma testosterone levels after chronic intensive marihuana use https://t.co/4u5Hm0xBtm “A reanalysis of existing data established that testosterone levels are depressed both after smoking one marijuana cigarette and after intravenous infusion of

Nov 1, 2024 · 5 likes · 37,244 followers View post →
Aureliano Stingi PhD
@AurelianoStingi · X

@AnnaK4202 https://t.co/Z4BTLyAnlC https://t.co/ObXXswzscs https://t.co/CruuG8bSYt

Feb 16, 2024 · 2 likes · 38,594 followers View post →
Martin Erlic
@SeloSlav · X

@IamLewisU Reduces testosterone and seems to be implicated in heart disease as well https://t.co/bIOav3dFyA

Jun 20, 2025 · 1 like · 17,638 followers View post →

All mentions

Martin Erlic
@SeloSlav · X

@IamLewisU Reduces testosterone and seems to be implicated in heart disease as well https://t.co/bIOav3dFyA

Jun 20, 2025 · 1 like · 17,638 followers View post →
Dr Vic, M.D. (ret)
@YouMayCallMeV1 · X

@christndominatr Kolodny 1974 didn't talk about homosexuality, you nincompoop. It was about low testosterone levels in straight men that used/abused cannabis. https://t.co/VFiv5tyG6r

Mar 26, 2025 · 2,405 followers View post →
Jared’s "Peace Plan" Failed
@JordanM10724168 · X

@JQRADIO247 https://t.co/S2DvWJVsWs

Jan 21, 2025 · 3,096 followers View post →
Richard Chlad
@jh57496292 · X

@skrblik https://t.co/b3nBHkyrvr

Nov 28, 2024 · 19 likes · 376 followers View post →
Nutrition Detective
@NutriDetect · X

@orlandoacu Paper: Depression of plasma testosterone levels after chronic intensive marihuana use https://t.co/4u5Hm0xBtm “A reanalysis of existing data established that testosterone levels are depressed both after smoking one marijuana cigarette and after intravenous infusion of

Nov 1, 2024 · 5 likes · 37,244 followers View post →
Senthes
@s3nthes · X

@FranklinCo33175 @Styx666Official https://t.co/eeLlbtbf1T https://t.co/j6v1cH5MUC

Sep 16, 2024 · 1 like · 114 followers View post →
Senthes
@s3nthes · X

@stewumd @AFpost https://t.co/eeLlbtbf1T https://t.co/j6v1cH5MUC https://t.co/3eHsA6v1hZ

Sep 13, 2024 · 114 followers View post →
renato
@vy4z_ · X

@henriqu3_valim @canabisbrasil https://t.co/34oA4NfPjz https://t.co/315XBlGJt9 https://t.co/bz2TS3epIe

Mar 12, 2024 · 228 followers View post →
Aureliano Stingi PhD
@AurelianoStingi · X

@AnnaK4202 https://t.co/Z4BTLyAnlC https://t.co/ObXXswzscs https://t.co/CruuG8bSYt

Feb 16, 2024 · 2 likes · 38,594 followers View post →
Roland
@Ro1ad0 · X

@urbcody DOI:10.1056/NEJM197404182901602 doi: 10.1016/0022-5193(83)90255-2

Dec 6, 2023 · 108 followers View post →
Roland
@Ro1ad0 · X

@marwadi_bhavik @el_elmis33 @DejaRu22 https://t.co/xSnv83m5A7 https://t.co/Kub5lKh5qa DOI:10.1056/NEJM197404182901602 doi: 10.1016/0022-5193(83)90255-2

Dec 6, 2023 · 1 like · 108 followers View post →
Miloslav Šindelář
@Milosval1 · X

Aug 22, 2023 · 16 likes · 16,101 followers View post →
Dontee Wrenn
@DonteeLWrenn · X

https://t.co/rPVgHP2aiD

Jul 21, 2023 · 737 followers View post →
Dr. M. Sorrenti
@MSorrenti2 · X

@Seekerof1Truth @AlpacaAurelius https://t.co/1xTjzamNqT https://t.co/1XTm6L8H17 https://t.co/bl2Gw8APoK https://t.co/utTy1XuZmv Cannabis is an unbelievably powerful plant if you use it right. Being a stoner is using it in the shittiest most disrespectful way possible and that will be reflected in your life.

Jan 19, 2023 · 9 followers View post →
Chirag Barjatya
@chiragbarjatyaa · X

Just like few people take that “high” from lighting weights which provides you Health benefits. REFERENCES 1.Kolodny, R.C., et al., Depression of plasma testosterone levels after chronic intensive marihuana use. 1974. 290(16): p. 872-874.

Dec 8, 2022 · 10 likes · 99,358 followers View post →
Johnny Concheroo ✝️
@JC_4570 · X

RT @JC_4570: @youngwisezoe @Th3Melan8dGawd https://t.co/UabtNCIqHB https://t.co/VL1AtLVu23 https://t.co/RIBFTkGfWr

Apr 8, 2022 · 1 share · 285 followers View post →
Johnny Concheroo ✝️
@JC_4570 · X

@youngwisezoe @Th3Melan8dGawd https://t.co/UabtNCIqHB https://t.co/VL1AtLVu23 https://t.co/RIBFTkGfWr

Apr 8, 2022 · 1 share · 285 followers View post →
Alcohol consumption lowers testosterone levels
Facebook

org/doi/full/10.1056/NEJM197404182901602 These numbers would be much lower in todays times being that the 500 ng/dl range on now considered ...

Sep 28, 2025 View →
Traitement naturel pour l'amélioration de la sexualité masculine ...
Reddit

... et spécialisées dans le domaine ;. https://www.nejm.org/doi/full/10.1056/NEJM197404182901602 · Réponses supplémentaires · gio_sdboy.

Sep 4, 2023 View →
Natural treatment for male sexual enhancement (diets, exercises ...
Reddit

... study done by a reputable people specialized in the field;. https://www.nejm.org/doi/full/10.1056/NEJM197404182901602 · More replies · gio_sdboy.

Sep 3, 2023 View →
男性性能力增强的自然疗法(饮食、锻炼等) : r/HubermanLab
Reddit

... 没读。 他们的信息来自一个由该领域知名人士进行的可靠研究;. https://www.nejm.org/doi/full/10.1056/NEJM197404182901602 · 更多回复 · gio_sdboy.

Sep 3, 2023 View →
I thoroughly enjoy smoking weed. : r/Testosterone
Reddit

... Medicine, hope they're legitimate enough for you: https://www.nejm.org/doi/full/10.1056/NEJM197404182901602 · More replies · ImproveEveryday77.

Aug 3, 2023 View →
Ich rauche total gerne Gras. : r/Testosterone - Reddit
Reddit

... Medicine, ich hoffe, die sind legitim genug für dich: https://www.nejm.org/doi/full/10.1056/NEJM197404182901602 · Weitere Antworten.

Aug 3, 2023 View →
There have been a number of reports in recent years that THC can ...
Facebook

https://www.nejm. org/doi/full/10.1056/NEJM197404182901602 These numbers would be much lower in todays times being that the 500 ng/dl range ...

Jan 30, 2023 View →
'DAGGA'S GOOD FOR SPERM' FOR years dagga ... - Facebook
Facebook

org/doi/full/10.1056/NEJM197404182901602 These numbers would be much lower in todays times being that the 500 ng/dl range on now considered ...

Feb 17, 2019 View →
45 days. Does weed mess with testosterone levels? : r/leaves
Reddit

http://www.nejm.org/doi/pdf/10.1056/NEJM197404182901602 · http://www.sciencedirect.com/science/article/pii/0022519383902552 · http://www ...

Apr 15, 2016 View →
Thoughts on Movement and Cannabis? : r/bodyweightfitness
Reddit

http://www.nejm.org/doi/pdf/10.1056/NEJM197404182901602 · http://www.ukcia.org/research/EndocrineEffects.pdf · http://www.sciencedirect.com ...

Jan 26, 2016 View →
Prenatal drug exposure possible cause for being transgender : r ...
Reddit

Well one of the studies I linked suggests that it is not a piss poor anti-androgen. http://www.nejm.org/doi/pdf/10.1056/NEJM197404182901602 " ...

Apr 30, 2015 View →