N Engl J Med March 1995 PMID 7632212

Changes in energy expenditure resulting from altered body weight.

R L Leibel, M Rosenbaum, J Hirsch

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Mentions

137
Peak: 1 in Feb 2019
across 5 sources since Feb 2019

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Feb 2019 – Sep 2025

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AI synopsis

What people are saying

The discussions demonstrate moderate interest and engagement by referencing specific studies and clinical questions, such as why obesity correlates with poverty and how metabolic responses are consistent across individuals. Participants use technical language and suggest practical solutions like increasing satiety, reflecting a thoughtful engagement with the publication's findings and broader implications.

AgreementModerate agreement

A majority of the discussions acknowledge the research's validity and mention supporting data, such as the reference to Leibel et al. (1995).

InterestModerate interest

Participants show curiosity about metabolic mechanisms and implications, with some suggesting practical applications like increasing satiety.

EngagementModerate engagement

The discussions include specific questions and references, indicating active engagement with the topic and related studies.

ImpactModerate impact

The conversations highlight the study's importance in understanding body weight and energy expenditure, which could influence future research and treatments.

Abstract in brief

  • Changes in body weight, whether gained or lost, significantly impact energy expenditure, with both obese and non-obese individuals showing similar metabolic responses.
  • Weight loss of 10% or more results in a decrease in total, resting, and nonresting energy expenditure by approximately 3 to 8 kcal per kilogram of fat-free mass per day, while weight gain produces an increase of similar magnitude.
  • These metabolic adjustments, including the thermic effect of feeding and nonresting energy expenditure, are consistent across different levels of obesity and are independent of gender, suggesting inherent metabolic responses to body weight changes.]

Top posts

Most liked on X and Bluesky
Harmless Frog
@FrogHarmless · X

@DrNadolsky Probably because we don't care to measure it. Who puts starving Africans or Indians in metabolic chambers to assess them for deviation from expected metabolic parameters? OTOH, we *do* have published experiments of this sort. https://t.co/uUNHi1KbH7 https://t.co/awjJJRotbu

Mar 26, 2021 · 6 likes · 503 followers View post →
HighSatiety Diet
@HighSatietydiet · X

Evidence indicates that appetite increases 100kcal for every 1kg of weight loss and energy expenditure may drop 15% for a 10% decrease in body weight. So what does this look like in practice! Increasing #satiety has to be the answer https://t.co/pTVSXJzo35 https://t.co/pUQYTzXuMT https://t.co/8gmbZ75o8F

Aug 29, 2023 · 1 like · 1,256 followers View post →
Nick Vardavas
@vardavas · X

² Leibel RL, Rosenbaum M, Hirsch J (1995). Changes in energy expenditure resulting from altered body weight. New England Journal of Medicine, 332:621-628.

Aug 28, 2024 · 134 followers View post →
Susie スージー(30kg減。睡眠1番大事ver.)
@susie_diet · X

Changes in energy expenditure resulting from altered body weight. - PubMed - NCBI https://t.co/JPwMP34v2j

Jun 15, 2019 · 104 followers View post →
Mlk
@Desideratamer · X

@GoldenGummo @random09871234 https://t.co/VwPvsTjfCp Pour l'étude,vous pouvez vous plonger dans celle-ci. Si vous avez besoin d'un résumé n'hésitez pas

Apr 30, 2024 · 87 followers View post →
ketaset999
@ketaset999 · X

@jayber__crow @horizontalescal @growing_daniel Why is obesity correlated with poverty? Why don’t gastrin (saity hormone) mimics work like glps do? Why do fecal transplants between non-obese and obese patients cause weight loss? Why do calories needed to lose the same weight differ between obese and non?https://t.co/YE40F6CRNk

May 21, 2025 · 22 followers View post →

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ketaset999
@ketaset999 · X

@jayber__crow @horizontalescal @growing_daniel Why is obesity correlated with poverty? Why don’t gastrin (saity hormone) mimics work like glps do? Why do fecal transplants between non-obese and obese patients cause weight loss? Why do calories needed to lose the same weight differ between obese and non?https://t.co/YE40F6CRNk

May 21, 2025 · 22 followers View post →
Nick Vardavas
@vardavas · X

² Leibel RL, Rosenbaum M, Hirsch J (1995). Changes in energy expenditure resulting from altered body weight. New England Journal of Medicine, 332:621-628.

Aug 28, 2024 · 134 followers View post →
Mlk
@Desideratamer · X

@GoldenGummo @random09871234 https://t.co/VwPvsTjfCp Pour l'étude,vous pouvez vous plonger dans celle-ci. Si vous avez besoin d'un résumé n'hésitez pas

Apr 30, 2024 · 87 followers View post →
HighSatiety Diet
@HighSatietydiet · X

Evidence indicates that appetite increases 100kcal for every 1kg of weight loss and energy expenditure may drop 15% for a 10% decrease in body weight. So what does this look like in practice! Increasing #satiety has to be the answer https://t.co/pTVSXJzo35 https://t.co/pUQYTzXuMT https://t.co/8gmbZ75o8F

Aug 29, 2023 · 1 like · 1,256 followers View post →
Harmless Frog
@FrogHarmless · X

@DrNadolsky Probably because we don't care to measure it. Who puts starving Africans or Indians in metabolic chambers to assess them for deviation from expected metabolic parameters? OTOH, we *do* have published experiments of this sort. https://t.co/uUNHi1KbH7 https://t.co/awjJJRotbu

Mar 26, 2021 · 6 likes · 503 followers View post →
Susie スージー(30kg減。睡眠1番大事ver.)
@susie_diet · X

Changes in energy expenditure resulting from altered body weight. - PubMed - NCBI https://t.co/JPwMP34v2j

Jun 15, 2019 · 104 followers View post →