Kidney Int August 1994 PMID 7967350

Intracellular glutathione influences collagen generation by mesangial cells.

Z Shan, D Tan, J Satriano, S Silbiger, D Schlondorff

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Mentions

5
Peak: 2 in Aug 2023
across 2 sources since Aug 2023

Extended reach

20,363
potential audience

Total likes

24

Video views

3,977

Mentions per month

Aug 2023 – May 2024

Where it's discussed

  • X / Twitter3 posts
  • YouTube2 videos

AI synopsis

What people are saying

The discussions reflect a basic understanding that intracellular GSH and redox states influence collagen generation, with posters questioning the effectiveness of collagen powders if cellular redox is compromised. The tone suggests curiosity and consideration of health implications, but without detailed analysis or strong opinions, indicating moderate interest and engagement.

AgreementNeither agree nor disagree

The posts acknowledge the importance of cellular redox states and GSH in collagen synthesis but do not explicitly endorse or oppose the findings, indicating a neutral stance overall.

InterestModerate interest

The discussion hints at relevance to health and DIY collagen supplementation, showing some curiosity but not deep exploration.

EngagementModerate engagement

Comments like emphasizing the connection between redox, ATP, and collagen reflect a moderate level of engagement, attempting to interpret the research implications.

ImpactModerate impact

The focus on how redox status influences collagen production suggests recognition of potential implications for health and dietary supplements, though the discussion remains superficial.

Abstract in brief

  • Intracellular glutathione (GSH) affects how mesangial cells produce collagen, which is important for kidney health, especially in conditions like diabetes.
  • Increasing GSH with N-acetylcysteine boosts collagen production and related gene activity, while decreasing GSH with BSO reduces collagen synthesis, indicating GSH's role in regulating gene expression.
  • The study suggests that the redox state of a cell, controlled by GSH levels, influences the transcription of genes related to collagen and TGF-beta, which could help explain changes in kidney tissue during injury.]

Top posts

Most liked on X and Bluesky
Live Vitae
@livevitaeuk · X

Turns out your collagen powders do not mean much if your redox is low and you're not making ATP + H302 inside your cells https://t.co/7Zn1ZvxwD2

May 2, 2024 · 24 likes · 1 share · 13,151 followers View post →
plantbhai - 3bdu Al-Hakim
@HakimBGZ · X

RT @livevitaeuk: Turns out your collagen powders do not mean much if your redox is low and you're not making ATP + H302 inside your cells…

May 3, 2024 · 1 share · 2,796 followers View post →

All mentions

Role of Glutathione in Cell Aging and Stem Cell Function

This video explores the anti-aging effects of glutathione and its impact on stem cell health, highlighting the importance of high glutathione levels for maintaining stem cell functions like migration and stemness, which…

VEITA · Aug 3, 2023 1,440 views
plantbhai - 3bdu Al-Hakim
@HakimBGZ · X

RT @livevitaeuk: Turns out your collagen powders do not mean much if your redox is low and you're not making ATP + H302 inside your cells…

May 3, 2024 · 1 share · 2,796 followers View post →
Live Vitae
@livevitaeuk · X

Turns out your collagen powders do not mean much if your redox is low and you're not making ATP + H302 inside your cells https://t.co/7Zn1ZvxwD2

May 2, 2024 · 24 likes · 1 share · 13,151 followers View post →
Yadira Tapia
@YadiraTapiaM · X

@DrMauricioGon https://t.co/9bOeiU8XH0

Nov 3, 2023 · 436 followers View post →