Am J Physiol September 1993 PMID 8214047

Regulation of endogenous fat and carbohydrate metabolism in relation to exercise intensity and duration.

J A Romijn, E F Coyle, L S Sidossis, A Gastaldelli, J F Horowitz, E Endert, R R Wolfe

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What people are saying

Contributors frequently reference seminal research by Romijn and discuss how differences in exercise intensity affect substrate usage, with phrases like 'exercise biochemistry publication' and 'landmark study' showcasing the perceived significance of the findings. The tone varies from excited to critical, which illustrates the article's broad relevance in both athletic and academic contexts.

AgreementModerate agreement

Most discussions reflect a general agreement with the findings of the publication, though there are some opposing views regarding basic physiology.

InterestHigh interest

Participants express high interest in the article, often referencing past studies to contextualize the current findings.

EngagementModerate engagement

Many contributors engage with the material on a surface level, but a few delve deeper into specific methodologies and implications of the research.

ImpactHigh impact

Several discussions highlight the article's potential impact on understanding exercise metabolism, suggesting it could influence future research and practices.

Abstract in brief

  • The study used stable isotope tracers and indirect calorimetry to analyze how fat and glucose metabolism are controlled during different exercise intensities and durations.
  • At lower exercise intensities (25% of VO2max), fat breakdown was maximized, while glucose utilization increased with higher intensities (65%-85% of VO2max).
  • Recovery from high-intensity exercise saw a brief drop in lipolysis but an increase in fatty acid release from triglycerides, showing that carbohydrate metabolism responds directly to exercise intensity while fat metabolism is regulated more complexly.

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筋肉博士
@muscle_penguin_ · X

参考文献 https://t.co/FxZgPvMdPt https://t.co/LEwXlnUWd8 https://t.co/r46tLFrNoJ

Oct 14, 2024 · 140 likes · 59 shares · 35,624 followers View post →
Katsu Funai
@KatsuFunai · X

A landmark exercise biochemistry publication 26 years ago today by Ed Coyle and Bob Wolfe's group. "Exercise Warburg effect", how substrate preference changes with exercise intensity, especially between 65% and 85% VO2max. @LabrosSidossis https://t.co/JZIuGCOstp https://t.co/InX1LOOvJ2

Sep 1, 2019 · 81 likes · 25 shares · 3,885 followers View post →
Gorka Nuñez
@gorkanunez · X

Desde las primeras publicaciones de Romijn, en el 93, y en posteriores trabajos, sabemos que a diferentes intensidades, el tipo de substrato preferencial varía: https://t.co/oQ3ZP7WifN https://t.co/eXb9HaTeXQ

Jan 15, 2021 · 23 likes · 4 shares · 2,769 followers View post →
限界を越える犬
@7T6On4L9hD4AiB1 · X

体重83.7 前日比-0.8 反省 ここの維持とどれだけ増えるかが大事になってくるので、体重が増えた要因を追求すること。 丹田に力入れすぎて、筋肉痛だった。 point 運動強度によって使うエネルギーは違う。 安静にしてる→脂肪 散歩とか早歩き→脂肪と糖 ジョギング→糖質 https://t.co/fXklGT1sIw https://t.co/RABRA1NvRH

Jul 8, 2025 · 21 likes · 225 followers View post →
ใบหม่อนจะเฮลตี้
@baimonxhealthy · X

แปะ ref ka https://t.co/AHUDHlwJk6 https://t.co/NzVQhZnfe6 https://t.co/UOfLhCliQD

Apr 3, 2024 · 20 likes · 15 shares · 32,400 followers View post →
J-Shira
@Team_inspire · X

30分からボーナスタイムに入るなんて話がいつから登場したのかが疑問なんですよね。 https://t.co/el5qu1kGjj ↑の1993年の論文では変化が無いことを確認してますし。糖質の貯蔵量や運動強度に応じて時間は関係なく脂質と糖質の利用は変化しますので。 https://t.co/uvzJpmkum0

Apr 30, 2020 · 18 likes · 1 share · 4,777 followers View post →

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限界を越える犬
@7T6On4L9hD4AiB1 · X

体重83.7 前日比-0.8 反省 ここの維持とどれだけ増えるかが大事になってくるので、体重が増えた要因を追求すること。 丹田に力入れすぎて、筋肉痛だった。 point 運動強度によって使うエネルギーは違う。 安静にしてる→脂肪 散歩とか早歩き→脂肪と糖 ジョギング→糖質 https://t.co/fXklGT1sIw https://t.co/RABRA1NvRH

Jul 8, 2025 · 21 likes · 225 followers View post →
joemiller1stO
@jmiller4252 · X

Carb metabolism directly affects fat oxidation. High carb intake increases insulin, which suppresses lipolysis (fat breakdown).

Jun 4, 2025 · 1 like · 90 followers View post →
David Yoshimura
@mmticpolyalloy · X

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Oct 16, 2024 · 59 shares · 498 followers View post →
3200Kelvin
@3200K · X

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てら~き(声:藤田淑子)バックアップ
@terra3_Gn8BU · X

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西国西京の室町人
@NuEk19D5GtH9N88 · X

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Oct 15, 2024 · 59 shares · 1,455 followers View post →
夢守雷樹@悲しみベーコン
@Raiju202 · X

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demio
@dzm_mzd · X

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奈月¥500 ギリギリで生きてた医
@michishirube_kk · X

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_kidn
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Kei Nishikawa
@KeiNishikawa3 · X

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Yasuko
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raki6104
@raki6104 · X

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Haruhiko Nagata
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第213機械室
@kikaisitsu · X

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クープクープ
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hisa
@hisa0001 · X

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ゆごさん
@yugosa_ja · X

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ものものものもの
@mononoken · X

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Shibuya, Nobuhiro
@nsh1960 · X

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ブチ
@taruto1224 · X

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はんぺん
@hanpensky · X

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時雨尚未知/makrone
@n_shigure · X

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月戌@相模国㌠
@_moondoggie · X

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星見当番@アストロお嬢様部活動日誌
@kaori_stargazer · X

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わーろっく
@tubuyakkuma · X

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アメジスト
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あきラバー
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うたまる神@穂むら
@utamaru_shin · X

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Simon.Zh
@TakuShinmin · X

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いわみこうぞう(
@MasaruKoga1975 · X

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味塩濃口
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シュリンプ
@ebichan19850512 · X

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海老カツ@疲労困憊
@ouiouivolbox · X

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ねふー
@nefu3 · X

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ab(エビ
@ab_c_san · X

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ウチダ勝晃
@uchida_katsuaki · X

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ヒサっち★入院中
@sayabasu2shin · X

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V子
@v_ko_ · X

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たてりく奈落天国
@KRNMSKY · X

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子供相談室
@out0724 · X

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もにお
@M0NI0 · X

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朝宮ひとみ
@HitomiDaisybell · X

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フルチン中年男性
@otakutokkai · X

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しのP⋈☀️9/7 コミトレ一般
@sino_p928 · X

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k_wakita 五月がステキなのは さんざしが咲くから(メイフラワー)♪
@k_wakita · X

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籠入猫
@trashcantiglets · X

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KirimiSakana/切身魚
@Kirimisakana · X

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ノーカウントP
@no_kan_ajikan · X

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一人なのに応援団
@kodomo_iryou135 · X

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アライさん
@JAPAN_Inflation · X

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みるふぃーゆ
@QF019 · X

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まー。
@s_mah · X

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クシネ
@hare_niji · X

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筋肉博士
@muscle_penguin_ · X

参考文献 https://t.co/FxZgPvMdPt https://t.co/LEwXlnUWd8 https://t.co/r46tLFrNoJ

Oct 14, 2024 · 140 likes · 59 shares · 35,624 followers View post →
p.29 ಥ⁠‿⁠ಥ
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วาวิเวียน_
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nothing but only me
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Meveole
@MeveoleJaYarr · X

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aikqueSUNG
@aikquesung · X

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Ellamora
@GL_221B · X

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punnattanan_|||♡
@punnattanan · X

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TheLittleKit lll
@TheLitt35335228 · X

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ใบหม่อนจะเฮลตี้
@baimonxhealthy · X

แปะ ref ka https://t.co/AHUDHlwJk6 https://t.co/NzVQhZnfe6 https://t.co/UOfLhCliQD

Apr 3, 2024 · 20 likes · 15 shares · 32,400 followers View post →
Aquiles
@Sapiensbici · X

RT @gorkanunez: Desde las primeras publicaciones de Romijn, en el 93, y en posteriores trabajos, sabemos que a diferentes intensidades, el…

Oct 20, 2023 · 4 shares · 163 followers View post →
Raúl Celdrán
@NTSAcademia · X

RT @RPuddick: @Nutradvance Lol. A complete misunderstanding of basic human physiology. @drandyphung please start by reading https://t.co/…

Jul 20, 2022 · 1 share · 3,025 followers View post →
Robbie Puddick (MSc, RNutr)
@RPuddick · X

@Nutradvance Lol. A complete misunderstanding of basic human physiology. @drandyphung please start by reading https://t.co/UJ6eD5JPs3 Then have a look at: https://t.co/1PdddyKXgM https://t.co/ziSKMx7jIb

Jul 19, 2022 · 4 likes · 1 share · 133 followers View post →
KirolXabi
@KirolXabi · X

RT @gorkanunez: Desde las primeras publicaciones de Romijn, en el 93, y en posteriores trabajos, sabemos que a diferentes intensidades, el…

Jun 10, 2021 · 4 shares · 1,071 followers View post →
reyna
@castilloreyna · X

RT @felipeisidro13: B) Tras la lipólisis localizada, la forma ideal de BETAOXIDAR los AG que hemos volcado a plasma es realizar un ejercici…

May 8, 2021 · 1 share · 1,347 followers View post →
Felipe Isidro
@felipeisidro13 · X

B) Tras la lipólisis localizada, la forma ideal de BETAOXIDAR los AG que hemos volcado a plasma es realizar un ejercicio cardiovascular de baja intensidad (50% VO2Max) https://t.co/Ctl2gzcLvb

May 8, 2021 · 15 likes · 1 share · 16,769 followers View post →
Teresa Ripoll
@TRipollDU · X

RT @gorkanunez: Desde las primeras publicaciones de Romijn, en el 93, y en posteriores trabajos, sabemos que a diferentes intensidades, el…

Feb 1, 2021 · 4 shares · 697 followers View post →
Karla Ziegler
@mariposatuitera · X

RT @gorkanunez: Desde las primeras publicaciones de Romijn, en el 93, y en posteriores trabajos, sabemos que a diferentes intensidades, el…

Jan 28, 2021 · 4 shares · 26,718 followers View post →
Gorka Nuñez
@gorkanunez · X

Desde las primeras publicaciones de Romijn, en el 93, y en posteriores trabajos, sabemos que a diferentes intensidades, el tipo de substrato preferencial varía: https://t.co/oQ3ZP7WifN https://t.co/eXb9HaTeXQ

Jan 15, 2021 · 23 likes · 4 shares · 2,769 followers View post →
Jamie Whitfield, PhD
@jwhitfie · X

@doctorinigo @GeorgeABrooks3 Also demonstrated by Romijn in 1993 https://t.co/yo8heqdcfL

Dec 9, 2020 · 5 likes · 2,341 followers View post →
イリエッティ
@irietty_tk · X

RT @Team_inspire: 30分からボーナスタイムに入るなんて話がいつから登場したのかが疑問なんですよね。 https://t.co/el5qu1kGjj ↑の1993年の論文では変化が無いことを確認してますし。糖質の貯蔵量や運動強度に応じて時間は関係なく脂質と糖…

Apr 30, 2020 · 1 share · 1,700 followers View post →
J-Shira
@Team_inspire · X

30分からボーナスタイムに入るなんて話がいつから登場したのかが疑問なんですよね。 https://t.co/el5qu1kGjj ↑の1993年の論文では変化が無いことを確認してますし。糖質の貯蔵量や運動強度に応じて時間は関係なく脂質と糖質の利用は変化しますので。 https://t.co/uvzJpmkum0

Apr 30, 2020 · 18 likes · 1 share · 4,777 followers View post →
Teppei Fujikawa 藤川哲兵
@TFUJIK · X

RT @KatsuFunai: A landmark exercise biochemistry publication 26 years ago today by Ed Coyle and Bob Wolfe's group. "Exercise Warburg effect…

Sep 6, 2019 · 25 shares · 431 followers View post →
University of Utah Center for Metabolic Health
@UtahCMH · X

RT @KatsuFunai: A landmark exercise biochemistry publication 26 years ago today by Ed Coyle and Bob Wolfe's group. "Exercise Warburg effect…

Sep 4, 2019 · 25 shares · 1,096 followers View post →
Herman Pontzer
@HermanPontzer · X

RT @KatsuFunai: A landmark exercise biochemistry publication 26 years ago today by Ed Coyle and Bob Wolfe's group. "Exercise Warburg effect…

Sep 4, 2019 · 25 shares · 12,040 followers View post →
Gordon Simpson
@ggsimpsonrun · X

RT @KatsuFunai: A landmark exercise biochemistry publication 26 years ago today by Ed Coyle and Bob Wolfe's group. "Exercise Warburg effect…

Sep 4, 2019 · 25 shares · 205 followers View post →
Raul
@RaulM06 · X

RT @KatsuFunai: A landmark exercise biochemistry publication 26 years ago today by Ed Coyle and Bob Wolfe's group. "Exercise Warburg effect…

Sep 3, 2019 · 25 shares · 855 followers View post →
Emme
@FindlingMary · X

RT @KatsuFunai: A landmark exercise biochemistry publication 26 years ago today by Ed Coyle and Bob Wolfe's group. "Exercise Warburg effect…

Sep 3, 2019 · 25 shares · 188 followers View post →
Tony Wolf
@tony__wolf · X

RT @KatsuFunai: A landmark exercise biochemistry publication 26 years ago today by Ed Coyle and Bob Wolfe's group. "Exercise Warburg effect…

Sep 3, 2019 · 25 shares · 666 followers View post →
Javier Gonzalez
@Gonzalez_JT · X

RT @KatsuFunai: A landmark exercise biochemistry publication 26 years ago today by Ed Coyle and Bob Wolfe's group. "Exercise Warburg effect…

Sep 3, 2019 · 25 shares · 10,172 followers View post →
Davide Malatesta
@DvDMalatesta · X

RT @KatsuFunai: A landmark exercise biochemistry publication 26 years ago today by Ed Coyle and Bob Wolfe's group. "Exercise Warburg effect…

Sep 3, 2019 · 25 shares · 497 followers View post →
Jan Flavanautemas
@jarnosine · X

RT @KatsuFunai: A landmark exercise biochemistry publication 26 years ago today by Ed Coyle and Bob Wolfe's group. "Exercise Warburg effect…

Sep 3, 2019 · 25 shares · 191 followers View post →
Jani Vaara
@JaniVaara · X

RT @KatsuFunai: A landmark exercise biochemistry publication 26 years ago today by Ed Coyle and Bob Wolfe's group. "Exercise Warburg effect…

Sep 3, 2019 · 25 shares · 597 followers View post →
APS Publications
@APSPublications · X

RT @KatsuFunai: A landmark exercise biochemistry publication 26 years ago today by Ed Coyle and Bob Wolfe's group. "Exercise Warburg effect…

Sep 3, 2019 · 25 shares · 7,352 followers View post →
Roberta Anding
@RobertaAnding · X

RT @KatsuFunai: A landmark exercise biochemistry publication 26 years ago today by Ed Coyle and Bob Wolfe's group. "Exercise Warburg effect…

Sep 3, 2019 · 25 shares · 5,996 followers View post →
Jose Antonio PhD
@JoseAntonioPhD · X

RT @KatsuFunai: A landmark exercise biochemistry publication 26 years ago today by Ed Coyle and Bob Wolfe's group. "Exercise Warburg effect…

Sep 3, 2019 · 25 shares · 22,168 followers View post →
GloNua
@GeraldByrne1 · X

RT @KatsuFunai: A landmark exercise biochemistry publication 26 years ago today by Ed Coyle and Bob Wolfe's group. "Exercise Warburg effect…

Sep 3, 2019 · 25 shares · 338 followers View post →
Bingfeng Wan, CSCS RSCC MA
@wanbingfeng · X

RT @KatsuFunai: A landmark exercise biochemistry publication 26 years ago today by Ed Coyle and Bob Wolfe's group. "Exercise Warburg effect…

Sep 3, 2019 · 25 shares · 144 followers View post →
Raúl Celdrán
@NTSAcademia · X

RT @KatsuFunai: A landmark exercise biochemistry publication 26 years ago today by Ed Coyle and Bob Wolfe's group. "Exercise Warburg effect…

Sep 3, 2019 · 25 shares · 3,025 followers View post →
Jhonny Diaz
@Jhonny_Diaz_ · X

RT @KatsuFunai: A landmark exercise biochemistry publication 26 years ago today by Ed Coyle and Bob Wolfe's group. "Exercise Warburg effect…

Sep 2, 2019 · 25 shares · 648 followers View post →
Dr. Carolyn Cummins
@CarolynLCummins · X

RT @KatsuFunai: A landmark exercise biochemistry publication 26 years ago today by Ed Coyle and Bob Wolfe's group. "Exercise Warburg effect…

Sep 2, 2019 · 25 shares · 801 followers View post →
Ayesha Saleem, PhD
@asaleem_ · X

RT @KatsuFunai: A landmark exercise biochemistry publication 26 years ago today by Ed Coyle and Bob Wolfe's group. "Exercise Warburg effect…

Sep 2, 2019 · 25 shares · 1,187 followers View post →
Ragul Selvamoorthy
@ragul_95 · X

RT @KatsuFunai: A landmark exercise biochemistry publication 26 years ago today by Ed Coyle and Bob Wolfe's group. "Exercise Warburg effect…

Sep 2, 2019 · 25 shares · 383 followers View post →
Bryan Jasker PT, DPT
@oval_MetFlex · X

RT @KatsuFunai: A landmark exercise biochemistry publication 26 years ago today by Ed Coyle and Bob Wolfe's group. "Exercise Warburg effect…

Sep 2, 2019 · 25 shares · 608 followers View post →
Nutrition 630
@Nutrition630 · X

RT @KatsuFunai: A landmark exercise biochemistry publication 26 years ago today by Ed Coyle and Bob Wolfe's group. "Exercise Warburg effect…

Sep 2, 2019 · 25 shares · 59 followers View post →
Peter Crawford
@ketonemics · X

RT @KatsuFunai: A landmark exercise biochemistry publication 26 years ago today by Ed Coyle and Bob Wolfe's group. "Exercise Warburg effect…

Sep 1, 2019 · 25 shares · 1,690 followers View post →
Katsu Funai
@KatsuFunai · X

A landmark exercise biochemistry publication 26 years ago today by Ed Coyle and Bob Wolfe's group. "Exercise Warburg effect", how substrate preference changes with exercise intensity, especially between 65% and 85% VO2max. @LabrosSidossis https://t.co/JZIuGCOstp https://t.co/InX1LOOvJ2

Sep 1, 2019 · 81 likes · 25 shares · 3,885 followers View post →