Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993). The paper that defined a field. A single mutation, in a single gene, doubles worm lifespan. There are genes that affect ageing rates and they can be altered. https://t.co/ht6UbayFX2
A C. elegans mutant that lives twice as long as wild type.
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Oct 2021 – Sep 2025Where it's discussed
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The collective discussions emphasize the groundbreaking nature of the 1993 discovery, with references to the original paper and subsequent advancements, such as new methods to manipulate longevity genes, illustrating sustained scholarly interest and perceived impact on aging research.
Most posts recognize and support the significance of the 1993 discovery by Kenyon and colleagues about gene mutations extending lifespan, indicating strong consensus on its importance.
Posts demonstrate high interest through references to foundational research, ongoing studies, and questions about implications for human aging, showing curiosity and engagement with the topic.
Many posts discuss the specifics of the research methods, historical context, and potential for future applications, reflecting deep involvement in understanding the science.
The discussions highlight how the research has shaped the field of aging, suggesting it has had a lasting influence on scientific understanding and future research directions.
Abstract in brief
- Mutations in the daf2 gene in *C. elegans* can nearly double their lifespan, and this longevity depends on the activity of another gene, daf16.
- Both daf2 and daf16 are involved in controlling the formation of dauer larvae, which are long-lived, developmentally arrested forms triggered by environmental stress.
- The research suggests that the increased lifespan is due to a specific longevity mechanism that can be separated from dauer formation, offering new insights into how lifespan can be regulated.]
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Most liked on X and BlueskyDay 24 "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993). https://t.co/9eQOoHzarh
A C. elegans mutant that lives twice as long as wild type (1993) Cynthia Kenyon's Letter to @Nature that inspired Joan Mannick's career: "Our findings raise the possibility that the longevity... results from a regulated lifespan extension mechanism."
sources https://t.co/wpkM2d1dKh https://t.co/6pVo4AYATk
Mutations in the daf-2 gene double the lifespan of C. elegans worms, but they have no effect on lifespan if the daf-16 gene is mutated. From Keyon et al. 1993. pubmed.ncbi.nlm.nih.gov/8247153/
A C. elegans mutant that lives twice as long as wild type (1993) Cynthia Kenyon & Ramon Tabtiang https://t.co/azHv109ohk
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Mutations in the daf-2 gene double the lifespan of C. elegans worms, but they have no effect on lifespan if the daf-16 gene is mutated. From Keyon et al. 1993. pubmed.ncbi.nlm.nih.gov/8247153/
sources https://t.co/wpkM2d1dKh https://t.co/6pVo4AYATk
In 1993 #scientist discovered that a single #gene #mutation can double the life of a #roundworm (C. Elegans). How many years will it take to double human's #lifespan? #research #science #immortality Source : https://t.co/qt7NRDUu2p
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993). https://t.co/9eQOoHzarh
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
Day 24 "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993). https://t.co/9eQOoHzarh
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
RT @NikoMcCarty: Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993).…
Day 24 of great biology papers. "A C. elegans mutant that lives twice as long as wild type," by Kenyon C. et al. (1993). The paper that defined a field. A single mutation, in a single gene, doubles worm lifespan. There are genes that affect ageing rates and they can be altered. https://t.co/ht6UbayFX2
RT @agingdoc1: A C. elegans mutant that lives twice as long as wild type (1993) Cynthia Kenyon's Letter to @Nature that inspired Joan Mann…
RT @agingdoc1: A C. elegans mutant that lives twice as long as wild type (1993) Cynthia Kenyon's Letter to @Nature that inspired Joan Mann…
A C. elegans mutant that lives twice as long as wild type (1993) Cynthia Kenyon's Letter to @Nature that inspired Joan Mannick's career: "Our findings raise the possibility that the longevity... results from a regulated lifespan extension mechanism."
@nir_eynon @HealthyLongeviT stupid question but: hasn't it been known for almost three decades? https://t.co/yWr7Ak3xr9
A C. elegans mutant that lives twice as long as wild type (1993) Cynthia Kenyon & Ramon Tabtiang https://t.co/azHv109ohk
@__JosephWilk A.1.3. BTW, after all these years, our lab just showed that degrading DAF-2 at the end of life is possible to double the lifespan. https://t.co/9jXAvYyU6m. A follow-up to Cynthia Kenyon’s original 1993 paper.
@__JosephWilk A.1.2. Of course, I read then the famous 1993 paper from Cynthia Kenyon (CK) about daf-2 doubling the lifespan of C. elegans https://t.co/9jXAvYyU6m. And begged a former post doc of CK, Joy Alcedo, who had a lab @FMIscience to take me on to do a masters working on aging.
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